- Treading Through Twilight. Anesthesiology 2023
- Annals Graphic Medicine - Preparing for a Genomic Future. Annals of internal medicine 2023
- "That Was Terrible": Public Humiliation in Preclinical Education. Academic medicine : journal of the Association of American Medical Colleges 2023
- Sunsets. JAMA oncology 2023
- Annals Graphic Medicine - Dependence. Annals of internal medicine 2023: eG220051
- Matter. Palliative & supportive care 2023: 1-2
- Lost and Found in the ER. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2023
- Bearer of bad news. Canadian medical education journal 2023; 14 (3): 360
- Celebrating synergy. Canadian medical education journal 2023; 14 (3): 361
My first day in the ER: Should I be worried about.
Families, systems & health : the journal of collaborative family healthcare
2023; 41 (2): 282
In this poem, a medical resident describes his first day in the emergency room. He describes the patient bleeding and his plummeting pulse. The resident wonders if he worries too much or whether, when it truly matters, he will be enough. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
View details for DOI 10.1037/fsh0000746
View details for PubMedID 37338452
Five visits with Diane.
Families, systems & health : the journal of collaborative family healthcare
2023; 41 (2): 284-285
This brief article is based on a patient's experience the author witnessed as a medical oncology scribe. The article describes five visits with a cancer patient named Diane as she started chemotherapy. Mere months since Diane's first visit, she died. The doctor read a slip of paper on her desk and told the author with tears in her eyes. The author turned over the visits she had with Diane, trying to find solace in the comfort she had in the end. It had all gone so fast, though. Four visits and she was gone. (PsycInfo Database Record (c) 2023 APA, all rights reserved).
View details for DOI 10.1037/fsh0000775
View details for PubMedID 37338454
- Bonfire Abecedarian. The Journal of medical humanities 2023
- Falling apart. Canadian medical education journal 2023; 14 (2): 181
- Growth mindset. AEM education and training 2023; 7 (2): e10847
- Keeping UpToDate. AEM education and training 2023; 7 (2): e10826
- Greener Health Care Is a Necessity. AMA journal of ethics 2023; 25 (4): E294-298
- Indelible. AEM education and training 2023; 7 (2): e10866
- Rheumatology's Animal Kingdom: A Digital Art Series. The Journal of rheumatology 2023
Factors of transurethral incision effectiveness for ureteroceles in pediatric patients: A 28-year, single-institution retrospective review.
Journal of pediatric urology
As a congenital anomaly, ureteroceles occur in 1 in 4000 children, and are usually diagnosed prenatally. However, there remains a lack of definite consensus on the optimal management of congenital ureteroceles.We evaluated factors associated with success of primary transurethral incision (TUI) in ureterocele pediatric patients.Demographic and clinical information for 120 pediatric patients who were diagnosed with congenital ureterocele between 1993 and 2021 at our institution were obtained through retrospective chart review. Data were analyzed using Fisher's exact tests, t-tests, and logistic regression with a significance threshold of p < 0.05. The primary outcome of ureterocele management was TUI effectiveness, defined by no need for further surgical intervention.Of the 120 patients (39 boys, 81 girls) with ureteroceles, 75 patients (22 boys, 53 girls) met our inclusion criteria of undergoing initial TUI ureterocele. Initial TUI was effective in 51/75 patients (68.0%). We analyzed possible correlative factors for TUI efficacy. Simplex system was a significant predictor of primary TUI efficacy (85% effective in simplex systems, 62% in duplex systems). Prior urinary tract infection, prenatal diagnosis, and electrocautery technique were all associated with an increased risk of needing additional surgeries after primary TUI.The most significant predictors of effective primary TUI were simplex system and the absence of preoperative vesicoureteral reflux. Prenatal diagnosis, preoperative febrile urinary tract infection, higher preoperative hydronephrosis grade, and the use of electrocautery were all associated with decreased primary TUI efficacy. Study limitations include that it was a retrospective chart review, and cohort size was limited by incomplete urology follow-up and operative records.Initial TUI was an effective procedure for the majority of our pediatric ureterocele patients, a higher success rate compared to other cohorts. Patients with a simplex system were more likely to have an effective first TUI than patients with duplex systems, as were patients without preoperative reflux. Although not statistically significant, our data suggest prior UTI, prenatal diagnosis, higher preoperative hydronephrosis grade, and the use of electrocautery may be associated with having additional surgeries.
View details for DOI 10.1016/j.jpurol.2023.02.020
View details for PubMedID 37002026
- Limbo. American journal of kidney diseases : the official journal of the National Kidney Foundation 2023
- Side effects acrostic. Palliative & supportive care 2023: 1
- Moments That Matter. Academic medicine : journal of the Association of American Medical Colleges 2023
- Sunrise, Sunset FAMILY MEDICINE 2023; 55 (1): 59-60
- In Line. American journal of kidney diseases : the official journal of the National Kidney Foundation 2022
- Rusty and Wooden. The Journal of rheumatology 2022; 49 (12): 1398-1399
- Pulchritudo ex machina: Beauty from the machine. Palliative & supportive care 2022: 1-2
- Captive. Tuberculosis and respiratory diseases 2022
- Worth Bearing in Mind. Academic medicine : journal of the Association of American Medical Colleges 2022
- Heavy hangs the coat. AEM education and training 2022; 6 (5): e10807
- From books to bedsides AEM EDUCATION AND TRAINING 2022; 6 (5): e10811
- Deluge. Journal of the American Geriatrics Society 2022
- Bedbound PALLIATIVE & SUPPORTIVE CARE 2022
- Safety Net. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2022
- Code. Academic emergency medicine : official journal of the Society for Academic Emergency Medicine 2022
- On a scale from one to ten. Palliative & supportive care 2022: 1
- Induction. Anesthesiology 2022
Letter from a medical oncology scribe
Palliative & Supportive Care
View details for DOI 10.1017/S1478951522000281
- On Diction. JAMA oncology 2021
High-Parametric Evaluation of Human Invariant Natural Killer T Cells to Delineate Heterogeneity in Allo- and Autoimmunity.
Human invariant natural killer T cells (iNKTs) are a rare innate-like lymphocyte population that recognize glycolipids presented on CD1d. Studies in mice have shown that these cells are heterogenous and capable of enacting diverse functions, and the composition of iNKT subsets can alter disease outcomes. In contrast, far less is known about how heterogeneity in human iNKTs relates to disease. To address this, we use a high-dimensional, data-driven approach to devise a framework to parse human iNKT heterogeneity. Our data revealed novel and previously described iNKT phenotypes with distinct functions. In particular, we found two phenotypes of interest: 1) a population with Th1 function that was increased with iNKT activation characterized by HLA-II+CD161- expression, and 2) a population with enhanced cytotoxic function characterized by CD4-CD94+ expression. These populations, respectively, correlate with acute graft-versus-host disease after allogeneic hematopoietic stem cell transplantation and with new onset type 1 diabetes. Our study identifies human iNKT phenotypes associated with human disease that could aid in the development of biomarkers or therapeutics targeting iNKTs.
View details for DOI 10.1182/blood.2019001903
View details for PubMedID 31935280