Professional Education


  • Doctor of Philosophy, Institute of Bioorganic Chemistry PAS, Chemistry/Biochemistry (2013)
  • Master of Science/Engineer, Poznań University of Life Sciences, Biotechnology (2008)
  • Master of Science/Engineer, Poznań University of Economics, Commodity of Science (2006)

Stanford Advisors


All Publications


  • Chemical and structural effects of base modifications in messenger RNA. Nature Harcourt, E. M., Kietrys, A. M., Kool, E. T. 2017; 541 (7637): 339-346

    Abstract

    A growing number of nucleobase modifications in messenger RNA have been revealed through advances in detection and RNA sequencing. Although some of the biochemical pathways that involve modified bases have been identified, research into the world of RNA modification - the epitranscriptome - is still in an early phase. A variety of chemical tools are being used to characterize base modifications, and the structural effects of known base modifications on RNA pairing, thermodynamics and folding are being determined in relation to their putative biological roles.

    View details for DOI 10.1038/nature21351

    View details for PubMedID 28102265