Honors & Awards


  • Gina Finzi Fellow, Lupus Foundation of America (2017)
  • Goldwater Scholar, Barry M. Goldwater Scholarship & Excellence in Education Foundation (2015-2016)
  • Rose Hills Scholar, Rose Hills Foundation (2014-2016)
  • Wasserman Scholar, Edith & Lew Wasserman Foundation (2016)

Education & Certifications


  • Bachelor of Science, University of California Los Angeles, Microbio., Immuno., & Mol. Gen (2017)

Clerkships


  • 2020 Winter - NENS 301A Neurology Core Clerkship
  • 2020 Winter - OBGYN 300A Obstetrics and Gynecology Core Clerkship
  • 2020 Winter - OPHT 398A Elective in Ophthalmology
  • 2019 Autumn - MED 300A Internal Medicine Core Clerkship
  • 2019 Autumn - PEDS 300A Pediatrics Core Clerkship
  • 2019 Summer - PSYC 300A Psychiatry Core Clerkship

All Publications


  • TOPOGRAPHIC OPTICAL COHERENCE TOMOGRAPHY SEGMENTATION SHOWS LIMITED ELLIPSOID ZONE RECOVERY IN MILD HYDROXYCHLOROQUINE RETINOPATHY. Retinal cases & brief reports de Sisternes, L., Pham, B. H., Durbin, M., Marmor, M. F. 2020

    Abstract

    PURPOSE: Optical coherence tomography (OCT) cross-sections have shown limited ellipsoid zone (EZ) improvement in mild hydroxychloroquine (HCQ) retinopathy within a few years after drug cessation. However, the extent, functional significance, and stability of such changes over time remain unclear.METHODS: We created en face EZ maps using automated pixel-by-pixel segmentation for four patients with early-moderate HCQ toxicity followed for 6-8 years after drug cessation. These maps were compared with OCT cross-sections, fundus autofluorescence, and automated 10-2 visual fields.RESULTS: One patient had no EZ line loss; one had stable EZ loss throughout follow-up; two showed 30 to 40% reduction in the area of loss, largely in the first 2 years. This limited recovery mostly occurred in regions where the EZ line was only thinned or fragmented; other similar areas did not improve. Fundus autofluorescence hyperfluorescence and visual fields did not show consistent correlation with topography.CONCLUSION: Anatomic EZ recovery, when present, was restricted to regions of mild damage and did not correlate with fundus autofluorescence or improvement in visual fields. Topographic mapping seemed no more sensitive locally than cross-sectional OCT but may aid detection and longitudinal follow-up of toxicity by showing early damage or changes in the macula that could be missed with individual cross-sections.

    View details for DOI 10.1097/ICB.0000000000000993

    View details for PubMedID 32150114

  • The rapid N-wave as a potentially useful measure of the photopic negative response. Documenta ophthalmologica. Advances in ophthalmology Pham, B. H., Goldberg, J. L., Marmor, M. F. 2020

    Abstract

    The photopic negative response (PhNR) correlates with ganglion cell function and has previously been examined as an indicator of glaucomatous optic nerve damage. However, it is a prolonged response that is measured against baseline, and its clinical utility has been limited by extensive variability, poor repeatability, and baseline instability. We have observed a distinct brief negative wave ("N-wave") commonly present within the slow PhNR trough, which may provide practical and analytic advantages as a clinical measure.We reviewed data from an interventional trial of 59 glaucoma patients who had 4 exams over an 8-month period. The PhNR was recorded with standard ISCEV stimuli (1 Hz and in some cases 4 Hz stimulation), and N-waves were measured manually, relative to return to baseline.N-waves, when present, could be measured easily despite shifting baselines and a degree of background noise. The PhNR median amplitude centered around 18 μV, while the N-wave median centered around 7 μV, with a distribution of responses skewed toward low or zero amplitudes.The N-wave appears to be a component of the longer PhNR, though its exact origin and significance remain unclear. As a rapid waveform that is independent of baseline, the N-wave is in many ways easier to measure accurately than the slower PhNR, which is highly dependent on baseline stability. The N-wave may prove useful clinically if further studies can optimize its stimulation, show its behavior in normal individuals and find correlation with markers of optic nerve disease.

    View details for DOI 10.1007/s10633-020-09769-w

    View details for PubMedID 32507902

  • Topography Shows Limited Ellipsoid Zone Recovery from Mild Hydroxychloroquine Toxicity Pham, B., De Sisternes, L., Durbin, M. K., Marmor, M. F. ASSOC RESEARCH VISION OPHTHALMOLOGY INC. 2019
  • PhNR measurement independent of baseline (N-wave) for the clinical evaluation of glaucoma Marmor, M. F., Pham, B., Goldberg, J. L. ASSOC RESEARCH VISION OPHTHALMOLOGY INC. 2019
  • SEQUENTIAL CHANGES IN HYDROXYCHLOROQUINE RETINOPATHY UP TO 20 YEARS AFTER STOPPING THE DRUG Implications for Mild Versus Severe Toxicity RETINA-THE JOURNAL OF RETINAL AND VITREOUS DISEASES Pham, B. H., Marmor, M. F. 2019; 39 (3): 492–501
  • Unilateral retinitis pigmentosa in children. Journal of AAPOS : the official publication of the American Association for Pediatric Ophthalmology and Strabismus Mercado, C. L., Pham, B. H., Beres, S., Marmor, M. F., Lambert, S. R. 2018

    Abstract

    BACKGROUND: Retinitis pigmentosa (RP) is a group of rare inherited retinal disorders characterized by diffuse progressive degeneration of the retina that typically presents bilaterally. Unilateral RP has not often been reported in children. We present a series of cases that illustrate discrimination between unilateral and asymmetric disease and between dystrophy and acquired degeneration.METHODS: Four patients (9-15 years of age; 3 females) were referred to our institution for possible unilateral RP based on fundus appearance and unilateral symptoms. All underwent full-field electroretinography (ERG), spectral domain optical coherence tomography (SD-OCT), widefield and color fundus photography, and fundus autofluorescence (FAF) imaging. Genetic testing and a vitamin and essential fatty acids panel were also conducted in 1 patient.RESULTS: Unilateral retinal degeneration was confirmed in 2 patients, whose fellow eyes showed no abnormalities on ERG or imaging. The other 2 patients were found to have highly asymmetric retinal degeneration based on ERG, wide-angle images, and repeated examinations (range, 0.3-9.8 years). Genetic testing and blood testing in 1 unilateral case were negative.CONCLUSIONS: Childhood-onset "unilateral RP" remains a difficult and uncertain diagnosis. ERG testing and longitudinal and widefield fundus examination are necessary to exclude asymmetrical disease. Although unilateral degeneration may exist in some children, its inherited or acquired etiology remains poorly understood.

    View details for PubMedID 30243749

  • Long-term progression of hydroxychloroquine retinopathy off the drug Pham, B., Marmor, M. F. ASSOC RESEARCH VISION OPHTHALMOLOGY INC. 2018
  • Responsiveness to X-Linked Toll-like Receptors Differs Between Mice with XY and XX Sex Chromosome Complement, Regardless of the Gonadal Sex Pham, B., Valera, I., Singh, R. R. WILEY. 2016
  • Investigating mechanisms of sex bias in lung fibrosis using mice with sex chromosome complement Valera, I. C., Kafaja, S., Pham, B., Fishbein, M., Singh, R. R. AMER ASSOC IMMUNOLOGISTS. 2016