Bio-X


Showing 1-20 of 43 Results

  • Ryann Fame, PhD

    Ryann Fame, PhD

    Assistant Professor of Neurosurgery

    Current Research and Scholarly InterestsEarly neural progenitors respond to extrinsic cues that maintain and support their potency. These stem/ progenitor cells are in direct contact with the cerebrospinal fluid (CSF), which acts as part of their niche. Our research program encompasses the early neural stem cell niche, neural tube closure, CSF, metabolism, and cortical neuronal development. We are dedicated to broad collaboration focused on translating an understanding of neurodevelopment and CSF biology into regenerative strategies.

  • Alice C. Fan

    Alice C. Fan

    Associate Professor of Medicine (Oncology) and, by courtesy, of Urology

    Current Research and Scholarly InterestsDr. Fan is a physician scientist who studies how turning off oncogenes (cancer genes) can cause tumor regression in preclinical and clinical translational studies. Based on her findings, she has initiated clinical trials studying how targeted therapies affect cancer signals in kidney cancer and low grade lymphoma. In the laboratory, she uses new nanotechnology strategies for tumor diagnosis and treatment to define biomarkers for personalized therapy.

  • Jonathan Fan

    Jonathan Fan

    Associate Professor of Electrical Engineering

    Current Research and Scholarly InterestsOptical engineering plays a major role in imaging, communications, energy harvesting, and quantum technologies. We are exploring the next frontier of optical engineering on three fronts. The first is new materials development in the growth of crystalline plasmonic materials and assembly of nanomaterials. The second is novel methods for nanofabrication. The third is new inverse design concepts based on optimization and machine learning.

  • Shanhui Fan

    Shanhui Fan

    Joseph and Hon Mai Goodman Professor of the School of Engineering and Professor, by courtesy, of Applied Physics

    BioFan's research interests are in fundamental studies of nanophotonic structures, especially photonic crystals and meta-materials, and applications of these structures in energy and information technology applications

  • C. Garrison Fathman

    C. Garrison Fathman

    Professor of Medicine (Immunology and Rheumatology), Emeritus

    Current Research and Scholarly InterestsMy lab of molecular and cellular immunology is interested in research in the general field of T cell activation and autoimmunity. We have identified and characterized a gene (GRAIL) that seems to control regulatory T cell (Treg) responsiveness by inhibiting the Treg IL-2 receptor desensitization. We have characterized a gene (Deaf1) that plays a major role in peripheral tolerance in T1D. Using PBC gene expression, we have provisionally identified a signature of risk and progression in T1D.

  • Michael Fayer

    Michael Fayer

    David Mulvane Ehrsam and Edward Curtis Franklin Professor of Chemistry

    BioMy research group studies complex molecular systems by using ultrafast multi-dimensional infrared and non-linear UV/Vis methods. A basic theme is to understand the role of mesoscopic structure on the properties of molecular systems. Many systems have structure on length scales large compare to molecules but small compared to macroscopic dimensions. The mesoscopic structures occur on distance scales of a few nanometers to a few tens of nanometers. The properties of systems, such as water in nanoscopic environments, room temperature ionic liquids, functionalized surfaces, liquid crystals, metal organic frameworks, water and other liquids in nanoporous silica, polyelectrolyte fuel cell membranes, vesicles, and micelles depend on molecular level dynamics and intermolecular interactions. Our ultrafast measurements provide direct observables for understanding the relationships among dynamics, structure, and intermolecular interactions.

    Bulk properties are frequently a very poor guide to understanding the molecular level details that determine the nature of a chemical process and its dynamics. Because molecules are small, molecular motions are inherently very fast. Recent advances in methodology developed in our labs make it possible for us to observe important processes as they occur. These measurements act like stop-action photography. To focus on a particular aspect of a time evolving system, we employ sequences of ultrashort pulses of light as the basis for non-linear methods such as ultrafast infrared two dimensional vibrational echoes, optical Kerr effect methods, and ultrafast IR transient absorption experiments.

    We are using ultrafast 2D IR vibrational echo spectroscopy and other multi-dimensional IR methods, which we have pioneered, to study dynamics of molecular complexes, water confined on nm lengths scales with a variety of topographies, molecules bound to surfaces, ionic liquids, and materials such as metal organic frameworks and porous silica. We can probe the dynamic structures these systems. The methods are somewhat akin to multidimensional NMR, but they probe molecular structural evolution in real time on the relevant fast time scales, eight to ten orders of magnitude faster than NMR. We are obtaining direct information on how nanoscopic confinement of water changes its properties, a topic of great importance in chemistry, biology, geology, and materials. For the first time, we are observing the motions of molecular bound to surfaces. In biological membranes, we are using the vibrational echo methods to study dynamics and the relationship among dynamics, structure, and function. We are also developing and applying theory to these problems frequently in collaboration with top theoreticians.

    We are studying dynamics in complex liquids, in particular room temperature ionic liquids, liquid crystals, supercooled liquids, as well as in influence of small quantities of water on liquid dynamics. Using ultrafast optical heterodyne detected optical Kerr effect methods, we can follow processes from tens of femtoseconds to ten microseconds. Our ability to look over such a wide range of time scales is unprecedented. The change in molecular dynamics when a system undergoes a phase change is of fundamental and practical importance. We are developing detailed theory as the companion to the experiments.

    We are studying photo-induced proton transfer in nanoscopic water environments such as polyelectrolyte fuel cell membranes, using ultrafast UV/Vis fluorescence and multidimensional IR measurements to understand the proton transfer and other processes and how they are influenced by nanoscopic confinement. We want to understand the role of the solvent and the systems topology on proton transfer dynamics.

  • Ron Fedkiw

    Ron Fedkiw

    Canon Professor in the School of Engineering

    BioFedkiw's research is focused on the design of new computational algorithms for a variety of applications including computational fluid dynamics, computer graphics, and biomechanics.

  • Vivian Feig

    Vivian Feig

    Assistant Professor of Mechanical Engineering and, by courtesy, of Materials Science and Engineering

    BioThe Feig lab aims to develop low-cost, noninvasive, and widely-accessible medical technologies that integrate seamlessly with the human body. We accomplish this by developing functional materials and devices with dynamic mechanical properties, leveraging chemistry and physics insights to engineer novel systems at multiple length scales. In pursuit of our goals, we maintain a strong emphasis on integrity and diversity, while nurturing the intellectual curiosity and holistic growth of our team members as researchers, communicators, and leaders.

  • Carl Feinstein

    Carl Feinstein

    Professor of Psychiatry and Behavioral Sciences at the Stanford University Medical Center, Emeritus

    Current Research and Scholarly InterestsAutism and Asperger's Disorder.

    Genetically-based neurodevelopmental disorder, including Velocardiofacial Syndrome, Smith-Magenis Syndrome, Williams Syndrome, and Fragile X Syndrome.

    Intellectual Disability (mental retardation) and psychiatric disorders.

    Developmental Language Disorder and Learning Disabilities.

    Sensory impairment in children, including visual and hearing impairment.

    Psychiatric aspects of medical illness and disability in children.

  • Jeffrey A. Feinstein, MD, MPH

    Jeffrey A. Feinstein, MD, MPH

    Dunlevie Family Professor of Pulmonary Vascular Disease and Professor, by courtesy, of Bioengineering

    Current Research and Scholarly InterestsResearch interests include (1) computer simulation and modeling of cardiovascular physiology with specific attention paid to congenital heart disease and its treatment, (2) the evaluation and treatment of pulmonary hypertension/pulmonary vascular diseases, and (3) development and testing of medical devices/therapies for the treatment of congenital heart disease and pulmonary vascular diseases.

  • Jessica Feldman

    Jessica Feldman

    Associate Professor of Biology

    Current Research and Scholarly InterestsCell differentiation requires cells to polarize, translating developmental information into cell-type specific arrangements of intracellular structures. The major goal of the research in my laboratory is to understand how cells build these functional intracellular patterns during development, specifically focusing on the molecules and mechanisms that build microtubules at cell-type specific locations and the polarity cues that guide this patterning in epithelial cells.

  • Marcus Feldman

    Marcus Feldman

    Burnet C. and Mildred Finley Wohlford Professor

    Current Research and Scholarly InterestsHuman genetic and cultural evolution, mathematical biology, demography of China

  • Dean W. Felsher

    Dean W. Felsher

    Professor of Medicine (Oncology) and of Pathology

    Current Research and Scholarly InterestsMy laboratory studies the molecular basis of cancer with a focus on understanding when cancer can be reversed through targeted oncogene inactivation.

  • Stephen Felt, DVM, MPH

    Stephen Felt, DVM, MPH

    Professor of Comparative Medicine

    Current Research and Scholarly InterestsHis research interests include infectious diseases, particularly zoonoses, and exploring techniques which promote the health and welfare of laboratory animals.

  • Liang Feng

    Liang Feng

    Associate Professor of Molecular and Cellular Physiology

    Current Research and Scholarly InterestsWe are interested in the structure, dynamics and function of eukaryotic transport proteins mediating ions and major nutrients crossing the membrane, the kinetics and regulation of transport processes, the catalytic mechanism of membrane embedded enzymes and the development of small molecule modulators based on the structure and function of membrane proteins.

  • Russell D. Fernald

    Russell D. Fernald

    Benjamin Scott Crocker Professor of Human Biology, Emeritus

    Current Research and Scholarly InterestsIn the course of evolution,two of the strongest selective forces in nature,light and sex, have left their mark on living organisms. I am interested in how the development and function of the nervous system reflects these events. We use the reproductive system to understand how social behavior influences the main system of reproductive action controlled by a collection of cells in the brain containing gonodotropin releasing hormone(GnRH)

  • Katherine Ferrara

    Katherine Ferrara

    Professor of Radiology (Molecular Imaging Program at Stanford)

    Current Research and Scholarly InterestsMy focus is image-guided drug and gene delivery and I am engaged in the design of imaging devices, molecularly-targeted imaging probes and engineered delivery vehicles, drawing upon my education in biology and imaging physics and more than 20 years of experience with the synthesis and labeling of therapeutic particles. My laboratory has unique resources for and substantial experience in synthetic chemistry and ultrasound, CT, MR and PET imaging.

  • James Ferrell

    James Ferrell

    Professor of Chemical and Systems Biology and of Biochemistry

    Current Research and Scholarly InterestsMy lab has two main goals: to understand the regulation of mitosis and to understand the systems-level logic of simple signaling circuits. We often make use of Xenopus laevis oocytes, eggs, and cell-free extracts for both sorts of study. We also carry out single-cell fluorescence imaging studies on mammalian cell lines. Our experimental work is complemented by computational and theoretical studies aimed at understanding the design principles and recurring themes of regulatory circuits.