Showing 51-74 of 74 Results
D. Craig Miller, M.D.
Thelma and Henry Doelger Professor of Cardiovascular Surgery, Emeritus
Current Research and Scholarly InterestsCardiac and heart valve disease with experimental laboratory large animal projects focused on the investigation of left ventricular and cardiac mechanics, bioenergetics, and LV and mitral valve physiology and pathophysiology. Current thrust is aimed at understanding the mitral valve and subvalvular mitral apparatus and transmural LV wall strains, thickening, and myolaminar fiber-sheet mechanics.
Clinical research interests include thoracic aortic diseases (aortic dissection, aneurysm) and cardiac valvular disease, including surgical treatment, endovascular thoracic aortic stent-graft repair, mitral valve repair, and valve-sparing aortic root replacement.
Professor of Civil and Environmental Engineering
BioBill Mitch received a B.A. in Anthropology (Archaeology) from Harvard University in 1993. During his studies, he excavated at Mayan sites in Belize and surveyed sites dating from 2,000 B.C. in Louisiana. He switched fields by receiving a M.S. degree in Civil and Environmental Engineering at UC Berkeley. He worked for 3 years in environmental consulting, receiving his P.E. license in Civil Engineering in California. Returning to UC Berkeley in 2000, he received his PhD in Civil and Environmental Engineering in 2003. He moved to Yale as an assistant professor after graduation. His dissertation received the AEESP Outstanding Doctoral Dissertation Award in 2004. At Yale, he serves as the faculty advisor for the Yale Student Chapter of Engineers without Borders. In 2007, he won a NSF CAREER Award. He moved to Stanford University as an associate professor in 2013.
Employing a fundamental understanding of organic chemical reaction pathways, his research explores links between public health, engineering and sustainability. Topics of current interest include:
Public Health and Emerging Carcinogens: Recent changes to the disinfection processes fundamental to drinking and recreational water safety are creating a host of highly toxic byproducts linked to bladder cancer. We seek to understand how these compounds form so we can adjust the disinfection process to prevent their formation.
Global Warming and Oceanography: Oceanic dissolved organic matter is an important global carbon component, and has important impacts on the net flux of CO2 between the ocean and atmosphere. We seek to understand some of the important abiotic chemical reaction pathways responsible for carbon turnover.
Sustainability and Persistant Organic Pollutants (POPs): While PCBs have been banned in the US, we continue to produce a host of structurally similar chemicals. We seem to understand important chemical pathways responsible for POP destruction in the environment, so we can design less persistent and problematic chemicals in the future.
Engineering for Sustainable Wastewater Recycling: The shortage of clean water represents a critical challenge for the next century, and has necessitated the recycling of wastewater. We seek to understand ways of engineer this process in ways to minimize harmful byproduct formation.
Carbon Sequestration: We are evaluating the formation of nitrosamine and nitraminecarcinogens from amine-based carbon capture, as well as techniques to destroy any of these byproducts that form.
George D. Smith Professor of Translational Medicine
Current Research and Scholarly InterestsTwo areas: 1. Using rationally-designed peptide inhibitors to study protein-protein interactions in cell signaling. Focus: protein kinase C in heart and large GTPases regulating mitochondrial dynamics in neurodegdenration. 2. Using small molecules (identified in a high throughput screens and synthetic chemistry) as activators and inhibitors of aldehyde dehydrogenases, a family of detoxifying enzymes, and glucose-6-phoshate dehydrogenase, in normal cells and in models of human diseases.
W. E. Moerner
Harry S. Mosher Professor and Professor, by courtesy, of Applied Physics
Current Research and Scholarly InterestsLaser spectroscopy and microscopy of single molecules to probe biological systems, one biomolecule at a time. Primary thrusts: fluorescence microscopy far beyond the optical diffraction limit (PALM/STORM/STED), methods for 3D optical microscopy in cells, and trapping of single biomolecules in solution for extended study. We explore protein localization patterns in bacteria, structures of amyloid aggregates in cells, signaling proteins in the primary cilium, and dynamics of DNA and RNA.
Denise M. Monack
Professor of Microbiology and Immunology
Current Research and Scholarly InterestsThe primary focus of my research is to understand the genetic and molecular mechanisms of intracellular bacterial pathogenesis. We use several model systems to study complex host-pathogen interactions in the gut and in immune cells such as macrophages and dendritic cells. Ultimately we would like to understand how Salmonella persists within certain hosts for years in the face of a robust immune response.
Obayashi Professor in the School of Engineering
Current Research and Scholarly InterestsHydrodynamics of lakes, estuaries, coral reefs, kelp forests and the coastal ocean
Associate Professor of Neurology and, by courtesy, of Neurosurgery, of Pediatrics, of Pathology and of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsThe Monje Lab studies the molecular and cellular mechanisms of postnatal neurodevelopment. This includes microenvironmental influences on neural precursor cell fate choice in normal neurodevelopment and in disease states.
Stephen B. Montgomery
Associate Professor of Pathology, of Genetics and, by courtesy, of Computer Science
Current Research and Scholarly InterestsWe focus on understanding the effects of genome variation on cellular phenotypes and cellular modeling of disease through genomic approaches such as next generation RNA sequencing in combination with developing and utilizing state-of-the-art bioinformatics and statistical genetics approaches. See our website at http://montgomerylab.stanford.edu/
Thomas Montine, MD, PhD
Stanford Medicine Professor of Pathology
BioDr. Montine received his education at Columbia University (BA in Chemistry), the University of Rochester (PhD in Pharmacology), and McGill University (MD and CM). His postgraduate medical training was at Duke University, and he was junior faculty at Vanderbilt University where he was awarded the Thorne Professorship in Pathology. In 2002, Dr. Montine was appointed as the Alvord Endowed Professor in Neuropathology and Director of the Division of Neuropathology at the University of Washington. He was Director of the University of Washington Alzheimer’s Disease Research Center, one of the original 10 Centers in the US, and passed that responsibility to able colleagues. In 2010, Dr. Montine was appointed Chair of the Department of Pathology at the University of Washington. In 2016, Dr. Montine was appointed Chair of the Department of Pathology at Stanford University where he is the Stanford Medicine Endowed Professor in Pathology.
Dr. Montine is the founding Director of the Pacific Udall Center, one of 9 NINDS-funded Morris K. Udall Centers of Excellence for Parkinson’s Disease Research. Our center performs basic, translational, and clinical research focused on cognitive impairment in Parkinson’s disease. The Pacific Udall Center emphasizes a vision for precision health that comprises functional genomics, development of surveillance tools for pre-clinical detection, and discovery of molecularly tailored therapies.
Dr. Montine is among the top recipients of NIH funding for all Department of Pathology faculty in the United States. He was the 2015 President of the American Association of Neuropathologists, and led or co-led recent NIH initiatives to revise diagnostic guidelines for Alzheimer’s disease (NIA), develop research priorities for the National Alzheimer’s Plan (NINDS and NIA), and develop research priorities for Parkinson’s Disease (NINDS).
The focus of the Montine Laboratory is on the structural and molecular bases of cognitive impairment with the goal of defining key pathogenic steps and thereby new therapeutic targets. The Montine Laboratory addresses these prevalent, unmet medical needs through a combination of neuropathology, biomarker development and application early in the course of disease, and experimental studies that test hypotheses concerning specific mechanisms of neuron injury and approaches to neuroprotection. PubMed lists 579 publications for Dr. Montine. Google Scholar estimates Dr. Montine’s citations as > 38,000, his i-10 index as 355, and his H-Index as 98. NIH iCite calculates (1995 to 2017) Dr. Montine’s weighted relative citation ratio as 2041.
Professor of Neurobiology
Current Research and Scholarly InterestsWe study neural mechanisms of visual-motor integration and the neural basis of cognition (e.g. attention). We study the activity of single neurons in visual and motor structures within the brain, examine how perturbing that activity affects neurons in other brain structures, and also how it affects the perceptual and
Associate Professor of Biology and Senior Fellow at the Woods Institute for the Environment
Current Research and Scholarly InterestsOur research focuses on the ecology of infectious disease. We are interested in how climate, species interactions, and global change drive infectious disease dynamics in humans and natural ecosystems. This research combines mathematical modeling and empirical work. Our main study systems include vector-borne diseases in humans and fungal pathogens in California grasses.
Assistant Professor (Research) of Neurology
BioDr. Beth Mormino completed a PhD in Neuroscience at UC Berkeley in the laboratory of Dr. William Jagust, where she performed some of the initial studies applying Amyloid PET with the tracer PIB to clinically normal older individuals. This initial work provided evidence that the pathophysiological processes of Alzheimer’s disease begin years before clinical symptoms and are associated with subtle changes to brain regions critical for memory. During her postdoctoral fellowship with Drs. Reisa Sperling and Keith Johnson at Massachusetts General Hospital she used multimodal imaging techniques to understand longitudinal cognitive changes among individuals classified as preclinical AD. In 2017, Dr. Mormino joined the faculty at Stanford University in the department of Neurology and Neurological Sciences. Her research program focuses on combining imaging and genetics to predict cognitive trajectories over time, and the integration of novel PET scans to better understand human aging and neurodegenerative diseases.
Associate Professor of Biology
Current Research and Scholarly InterestsOur research interests are to elucidate the contribution of chromatin to mechanisms that promote genomic integrity.
Professor of Radiology (Radiological Sciences Lab)
Current Research and Scholarly InterestsMR physics into tissue contrast mechanisms such as diffusion, perfusion, and functional imaging describes the research direction. Applications of cerebral stroke (brain attacks) and neurocognitive disorders are also being developed from these methods
Darius M. Moshfeghi, MD
Professor of Ophthalmology
Current Research and Scholarly InterestsDr. Moshfeghi leads the Stanford University Network for Diagnosis of Retinopathy of Prematurity (SUNDROP network). The SUNDROP network utilizes RetCam 3 cameras to provide remote screening of retinopathy of prematurity at outlying neonatal intensive care units. Active sites include Dominican Hospital, Santa Clara Valley Medical Center, and O'Connor Hospital.
Heather E. Moss, MD, PhD
Associate Professor of Ophthalmology and of Neurology
Current Research and Scholarly InterestsI am a clinician scientist with a background in engineering, epidemiology and neuro-ophthalmology. In my research, I combine tools from these disciplines with the goal of understanding and preventing vision loss from optic nerve diseases. My focus is on papilledema, the swelling of the optic nerve head due to elevation in intracranial pressure, which we are characterizing using electrophysiological and imaging techniques. Other areas of interest are peri-operative vision loss and optic neuritis.
Associate Professor (Research) of Psychiatry and Behavioral Sciences (Major Laboratories and Clinical Translational Neurosciences Incubator)
BioExpertise: Neurobiology, Sleep sciences, Molecular Genetics, Developmental Biology, Gene Silencing/Epigenetics
Methodology: Synapse Imaging (Two photon microscopy, Array Tomography), Calcium Imaging (Light Sheet Microscopy/SPIM, Light Field Microscopy), Optogenetics, CLARITY, Tol2 transgenesis, TALENs, CRISPR/Cas9, Video tracking and behavior computation.
Prithvi Mruthyunjaya, MD, MHS
Associate Professor of Ophthalmology
Current Research and Scholarly InterestsDr Mruthyunjaya has maintained a broad research interest with publications in both ocular oncology and retinal diseases.
His focus is on multi-modal imaging of ocular tumors and understanding imaging clues that may predict vision loss after ocular radiation therapy. He coordinates multi-center research on the role of genetic testing and outcomes of treatments of ocular melanoma.
In the field of retinal diseases, his interests are in intra-operative imaging to enhance surgical accuracy.
Mary Beth Mudgett
Senior Associate Dean for Undergraduate Educational Initiatives and Professor of Biology
Current Research and Scholarly InterestsMy laboratory investigates how bacterial pathogens employ proteins secreted by the type III secretion system (TTSS) to manipulate eukaryotic signaling to promote disease. We study TTSS effectors in the plant pathogen Xanthomonas euvesicatoria, the causal agent of bacterial spot disease of pepper and tomato. For these studies, we apply biochemical, cell biological, and genetic approaches using the natural hosts and model pathosystems.
Professor of Electrical EngineeringOn Partial Leave from 10/01/2021 To 03/31/2022
BioBoris Murmann is a Professor of Electrical Engineering at Stanford University. He joined Stanford in 2004 after completing his Ph.D. degree in electrical engineering at the University of California, Berkeley in 2003. From 1994 to 1997, he was with Neutron Microelectronics, Germany, where he developed low-power and smart-power ASICs in automotive CMOS technology. Since 2004, he has worked as a consultant with numerous Silicon Valley companies. Dr. Murmann’s research interests are in mixed-signal integrated circuit design, with special emphasis on sensor interfaces, data converters and custom circuits for machine learning. In 2008, he was a co-recipient of the Best Student Paper Award at the VLSI Circuits Symposium and a recipient of the Best Invited Paper Award at the IEEE Custom Integrated Circuits Conference (CICC). He received the Agilent Early Career Professor Award in 2009 and the Friedrich Wilhelm Bessel Research Award in 2012. He has served as an Associate Editor of the IEEE Journal of Solid-State Circuits, as well as the Data Converter Subcommittee Chair and the Technical Program Chair of the IEEE International Solid-State Circuits Conference (ISSCC). He is the founding faculty co-director of the Stanford SystemX Alliance and the faculty director of Stanford's System Prototyping Facility (SPF). He is a Fellow of the IEEE.
Professor of Medicine (Biomedical Informatics) and of Biomedical Data ScienceOn Partial Leave from 10/01/2020 To 03/31/2022
Current Research and Scholarly InterestsIt's important to ensuring that experimental data—and descriptions of the methods used to generate and analyze the data—are available online. Our laboratory studies methods for creating more comprehensive metadata descriptions both of data and of experiments that can be processed both by other scientists and by computers. We are also working to clean up legacy data and metadata to facilitate open science broadly. Other work focuses on management of knowledge using knowledge graphs.
David Myung, MD, PhD
Assistant Professor of Ophthalmology and, by courtesy, of Chemical Engineering
Current Research and Scholarly InterestsNovel biomaterials to reconstruct the wounded cornea
Mesenchymal stem cell therapy for corneal and ocular surface regeneration
Engineered biomolecule therapies for promote corneal wound healing
Telemedicine in ophthalmology