Bio-X


Showing 21-40 of 52 Results

  • Mark Pegram

    Mark Pegram

    Susy Yuan-Huey Hung Professor

    Current Research and Scholarly InterestsMolecular mechanisms of targeted therapy resistance in breast and other cancers

  • Norbert Pelc

    Norbert Pelc

    Boston Scientific Applied Biomedical Engineering Professor and Professor of Radiology, Emeritus

    Current Research and Scholarly InterestsBroadly, Dr. Pelc is interested in the physics, engineering and mathematics of medical imaging, especially computed tomography, digital x-ray imaging, magnetic resonance imaging, and hybrid multimodality systems. His current research is concentrated in the development of computed tomography systems with higher image quality and dose efficiency, in the characterization of system performance, and in the development and validation of new clinical applications.

  • Gary Peltz

    Gary Peltz

    Professor of Anesthesiology, Perioperative and Pain Medicine

    Current Research and Scholarly InterestsThe laboratory develops and uses state of the art genomic methods to identify genetic factors affecting disease susceptibility, and to translate these findings into new treatments. We have developed a more efficient method for performing mouse genetic analysis, which has been used to analyze the genetic basis for 16 different biomedical traits. We are developing novel methods, and have developed a novel experimental platform that replaces mouse liver with functioning human liver tissue.

  • Jon-Paul Pepper

    Jon-Paul Pepper

    Assistant Professor of Otolaryngology (Facial Plastic and Reconstructive Surgery) at the Stanford University Medical Center

    Current Research and Scholarly InterestsFacial paralysis is a debilitating condition that affects thousands of people. Despite excellent surgical technique, we are currently limited by the regenerative capacity of the body. The mission of our research is to identify new treatments that improve current facial paralysis treatments. We do this by exploring the regenerative cues that the body uses to restore tissue after nerve injury, in particular through pathways of neurogenesis and nerve repair in small mammals.

  • Dmitri Petrov

    Dmitri Petrov

    Michelle and Kevin Douglas Professor in the School of Humanities and Sciences

    Current Research and Scholarly InterestsEvolution of genomes and population genomics of adaptation and variation

  • Suzanne Pfeffer

    Suzanne Pfeffer

    Emma Pfeiffer Merner Professor in the Medical Sciences

    Current Research and Scholarly InterestsThe major focuses of our research is to understand the molecular basis of inherited Parkinson's Disease (PD) and to elucidate the molecular mechanisms by which proteins and cholesterol are transported between specific membrane compartments. We focus on the LRRK2 kinase that is inappropriately activated in PD and how it phosphorylates Rab GTPases, blocking the formation of primary cilia in culture and specific regions of the brain.

  • Adolf Pfefferbaum

    Adolf Pfefferbaum

    Professor of Psychiatry and Behavioral Sciences, Emeritus

    Current Research and Scholarly InterestsDevelopment and application of magnetic resonance imaging approaches for in vivo studies of human and animal brain integrity in neurodegenerative conditions, including alcoholism, HIV infection, Alzheimer's disease, and normal aging

  • Benjamin Pinsky

    Benjamin Pinsky

    Associate Professor of Pathology and of Medicine (Infectious Diseases) and, by courtesy, of Pediatrics (Infectious Diseases) at the Stanford University Medical Center

    Current Research and Scholarly InterestsDevelopment and application of molecular assays for the diagnosis and management of infectious diseases.

  • Peter Pinsky

    Peter Pinsky

    Professor of Mechanical Engineering, Emeritus

    BioPinsky works in the theory and practice of computational mechanics with a particular interest in multiphysics problems in biomechanics. His work uses the close coupling of techniques for molecular, statistical and continuum mechanics with biology, chemistry and clinical science. Areas of current interest include the mechanics of human vision (ocular mechanics) and the mechanics of hearing. Topics in the mechanics of vision include the mechanics of transparency, which investigates the mechanisms by which corneal tissue self-organizes at the molecular scale using collagen-proteoglycan-ion interactions to explain the mechanical resilience and almost perfect transparency of the tissue and to provide a theoretical framework for engineered corneal tissue replacement. At the macroscopic scale, advanced imaging data is used to create detailed models of the 3-D organization of collagen fibrils and the results used to predict outcomes of clinical techniques for improving vision as well as how diseased tissue mechanically degrades. Theories for mass transport and reaction are being developed to model metabolic processes and swelling in tissue. Current topics in the hearing research arena include multiscale modeling of hair-cell mechanics in the inner ear including physical mechanisms for the activation of mechanically-gated ion channels. Supporting research addresses the mechanics of lipid bilayer cell membranes and their interaction with the cytoskeleton. Recent past research topics include computational acoustics for exterior, multifrequency and inverse problems; and multiscale modeling of transdermal drug delivery. Professor Pinsky currently serves as Chair of the Mechanics and Computation Group within the Department of Mechanical Engineering at Stanford.

  • Sharon Pitteri

    Sharon Pitteri

    Associate Professor (Research) of Radiology (Cancer Early Detection-Canary Center)

    Current Research and Scholarly InterestsThe Pitteri laboratory is focused on the discovery and validation of proteins that can be used as molecular indicators of risk, diagnosis, progression, and recurrence of cancer. Proteomic technologies, predominantly mass spectrometry, are used to identify proteins in the blood that are differentially regulated and/or post-translationally modified with disease state. Using human plasma samples, tumor tissue, cancer cell lines, and genetically engineered mouse models, the origins of these proteins are being investigated. A major goal of this research is to define novel molecular signatures for breast and ovarian cancers, including particular sub-types of these diseases. This laboratory is also focused on the identification of proteins with expression restricted to the surface of cancer cells which can be used as novel targets for molecular imaging technologies.

  • Giles W Plant

    Giles W Plant

    Associate Professor of Neurosurgery

    Current Research and Scholarly InterestsOur research focuses on the repair of the injured spinal cord. We investigate the following areas:
    - Spinal cord injury (SCI): Axonal regeneration, myelination and gene therapy
    - Stem cell transplantation (adult, embryonic and iPS)
    - Endogenous stem cell activity after SCI

  • Sylvia K. Plevritis, PhD

    Sylvia K. Plevritis, PhD

    Professor of Biomedical Data Science and of Radiology (Integrative Biomedical Imaging Informatics at Stanford)

    Current Research and Scholarly InterestsMy research program focuses on computational modeling of cancer biology and cancer outcomes. My laboratory develops stochastic models of the natural history of cancer based on clinical research data. We estimate population-level outcomes under differing screening and treatment interventions. We also analyze genomic and proteomic cancer data in order to identify molecular networks that are perturbed in cancer initiation and progression and relate these perturbations to patient outcomes.

  • Jim Plummer

    Jim Plummer

    John M. Fluke Professor of Electrical Engineering and Professor, by courtesy, of Materials Science and Engineering

    Current Research and Scholarly InterestsGenerally studies the governing physics and fabrication technology of silicon integrated circuits, including the scaling limits of silicon technology, and the application of silicon technology outside traditional integrated circuits, including power switching devices such as IGBTs. Process simulation tools like SUPREM for simulating fabrication. Recent work has focused on wide bandgap semiconductor materials, particularly SiC and GaN, for power control devices.

  • Kilian M Pohl

    Kilian M Pohl

    Associate Professor (Research) of Psychiatry and Behavioral Sciences (Public Mental Health and Population Sciences)

    Current Research and Scholarly InterestsThe foundation of the laboratory of Associate Professor Kilian M. Pohl, PhD, is computational science aimed at identifying biomedical phenotypes improving the mechanistic understanding, diagnosis, and treatment of neuropsychiatric disorders. The biomedical phenotypes are discovered by unbiased, machine learning-based searches across biological, neuroimaging, and neuropsychological data. This data-driven discovery currently supports the adolescent brain research of the NIH-funded National Consortium on Alcohol and NeuroDevelopment in Adolescence (NCANDA) and the Adolescent Brain Cognitive Development (ABCD), the largest long-term study of brain development and child health in the US. The laboratory also investigates brain patterns specific to alcohol use disorder and the human immunodeficiency virus (HIV) across the adult age range, and have advanced the understanding of a variety of brain diseases including schizophrenia, Alzheimer’s disease, glioma, and aging.

  • Mary Polan

    Mary Polan

    Katharine Dexter McCormick and Stanley McCormick Memorial Professor in the School of Medicine, Emerita

    Current Research and Scholarly InterestsDr. Polan's research has centered around ovarian function during both the follicular and luteal phases. Studies of steroidogenesis, LH receptor synthesis, and the involvement of the plasminogen activator system in ovarian events have been performed.

  • Russell Poldrack

    Russell Poldrack

    Albert Ray Lang Professor of Psychology and Professor, by courtesy, of Computer Science

    Current Research and Scholarly InterestsOur lab uses the tools of cognitive neuroscience to understand how decision making, executive control, and learning and memory are implemented in the human brain. We also develop neuroinformatics tools and resources to help researchers make better sense of data.

  • Jonathan Pollack

    Jonathan Pollack

    Professor of Pathology

    Current Research and Scholarly InterestsResearch in the Pollack lab centers on translational genomics, with a focus on human cancer. The lab employs next-generation sequencing, single-cell genomics, genome editing, and cell/tissue-based modeling to uncover disease mechanisms, biomarkers and therapeutic targets. Current areas of emphasis include diseases of the prostate (prostate cancer and benign prostatic hyperplasia), as well as odontogenic neoplasms.

  • Ada Poon

    Ada Poon

    Associate Professor of Electrical Engineering

    Current Research and Scholarly InterestsOur research focuses on providing theoretical foundations and engineering platforms for realizing electronics that seamlessly integrate with the body. Such systems will allow precise recording or modulation of physiological activity, for advancing basic scientific discovery and for restoring or augmenting biological functions for clinical applications.

  • Richard Popp

    Richard Popp

    Professor of Medicine (Cardiovascular Medicine), Emeritus

    Current Research and Scholarly InterestsAcademic-Industrial relations; Ethics of invention.