Bio-X


Showing 81-100 of 114 Results

  • George Somero

    George Somero

    David and Lucile Packard Professor in Marine Science, Emeritus

    Current Research and Scholarly InterestsWe examine two aspects of organism-environment interactions: How does stress from physical (e.g., temperature) and chemical (oxygen levels, pH) factors perturb organisms and how do organisms respond, adaptively, to cope with this stress? We examine evolutionary adaptation and phenotypic acclimatization using a wide variety of marine animals, including Antarctic fishes and invertebrates from intertidal habitats on the coastlines of temperate and tropical seas.

  • Geoffrey Sonn

    Geoffrey Sonn

    Associate Professor of Urology and, by courtesy, of Radiology (Body MRI)

    Current Research and Scholarly InterestsMy interest is in improving prostate cancer diagnosis through MRI and image-targeted prostate biopsy. In collaboration with radiologists at Stanford, we are working to define the optimal role of MRI in prostate cancer. We hope to improve cancer imaging to the point that some men with elevated PSA may safely avoid prostate biopsy. For those who need biopsy, we are evaluating novel MRI-US fusion targeted biopsy, a technique that greatly improves upon the conventional biopsy method.

  • Justin L. Sonnenburg

    Justin L. Sonnenburg

    Alex and Susie Algard Endowed Professor

    Current Research and Scholarly InterestsThe goals of the Sonnenburg Lab research program are to (i) elucidate the basic mechanisms that underlie dynamics within the gut microbiota and (ii) devise and implement strategies to prevent and treat disease in humans via the gut microbiota. We investigate the principles that govern gut microbial community function and interaction with the host using a broad range of experimental approaches including studies of microbiomes in diverse human cohorts.

  • Erik Sperling

    Erik Sperling

    Associate Professor of Earth and Planetary Sciences and Senior Fellow at the Woods Institute for the Environment
    On Leave from 01/01/2024 To 08/31/2024

    Current Research and Scholarly InterestsThe research interests in the Sperling Lab are Earth history and the evolution of life, and the interactions between the biosphere and the geosphere. As such this research can generally be considered paleontology, insofar as paleontology encompasses all aspects of the history of life.

    Consequently, we define our research agenda by the questions we are interested in, rather than the tools used. This research incorporates multiple lines of evidence, and multiple tools, to investigate questions in the history of life. These lines of evidence include fossil data, molecular phylogenetics, sedimentary geochemistry, and developmental and ecological data from modern organisms. Ultimately, the goal is to link environmental change with organismal and ecological response through the lens of physiology.

    Our field research takes place all over the world--current areas include:

    -NW Canada (Yukon and Northwest Territories): Research has been conducted on the early Neoproterozoic Fifteenmile Group, Cryogenian and Ediacaran Windermere Supergroup, and on the Ordovician-Devonian Road River Group in the southern Richardson Mountains
    -Southern Canadian Cordillera: Work here has focused on the early Cambrian Mural Formation and its soft-bodied fauna.
    -England and Wales: Cambrian-Silurian successions in the Welsh Basin
    -Namibia: Ediacaran Nama Group
    -Upwelling zones: We study the oxygen minimum zone offshore California as an analogue for ancient low-oxygen oceans.

  • Edda Spiekerkoetter

    Edda Spiekerkoetter

    Associate Professor of Medicine (Pulmonary and Critical Care Medicine)

    Current Research and Scholarly InterestsPulmonary Arterial Hypertension
    Pulmonary Vascular Remodeling
    Modulation of BMPR, ENG, ACVRL1 (ALK1), SMAD signaling
    Structural and molecular programs governing right ventricular adaptation and failure
    Hereditary Hemorrhagic Telangiectasia
    Pulmonary Arteriovenous malformations
    Computational Drug Prediction and Repurposing
    Deep Tissue Confocal Imaging

  • Daniel Spielman

    Daniel Spielman

    Professor of Radiology (Radiological Sciences Lab) and, by courtesy, of Electrical Engineering

    Current Research and Scholarly InterestsMy research interests are in the field of medical imaging, particularly magnetic resonance imaging and in vivo spectroscopy. Current projects include MRI and MRS at high magnetic fields and metabolic imaging using hyperpolarized 13C-labeled MRS.

  • Alfred M. Spormann

    Alfred M. Spormann

    Professor of Civil and Environmental Engineering and of Chemical Engineering, Emeritus

    Current Research and Scholarly InterestsMetabolism of anaerobic microbes in diseases, bioenergy, and bioremediation

  • James Spudich

    James Spudich

    Douglass M. and Nola Leishman Professor of Cardiovascular Disease, Emeritus

    Current Research and Scholarly InterestsThe general research interest of this laboratory is the molecular basis of cell motility, with a current emphasis on power output by the human heart. We have three specific research interests, the molecular basis of energy transduction that leads to ATP-driven myosin movement on actin, the biochemical basis of the regulation of actin and myosin interaction and their assembly states, and the roles these proteins play in vivo, in cell movement, changes in cell shape and muscle contraction.

  • Randall Stafford

    Randall Stafford

    Professor of Medicine (Stanford Center for Research in Disease Prevention)

    Current Research and Scholarly InterestsAs Director of the SPRC Program on Prevention Outcomes and Practices, my work focuses on cardiovascular disease treatment and prevention, the adoption of new technology and practices, and patterns of physician practice, particularly medication prescribing. Specific interests include measuring and improving the quality of outpatient care, disparities in health care by race, gender, age and socioeconomic status, and interventions to improve prevention outcomes.

  • Konstantina M. Stankovic, MD, PhD, FACS

    Konstantina M. Stankovic, MD, PhD, FACS

    Bertarelli Foundation Professor and Professor of Otolaryngology - Head & Neck Surgery (OHNS) and, by courtesy, of Neurosurgery

    Current Research and Scholarly InterestsOur investigative efforts are organized along 3 research thrusts:
    1. Vestibular schwannoma: uncovering mechanisms of sensorineural hearing loss (SNHL) and identifying better therapies;
    2. High-resolution imaging of the inner ear;
    3. Novel sensing of and therapies for SNHL.
    Given the complex, multifaceted nature of these problems, our approach to them involves domain-specific customization and fusion of tools from molecular biology, systems neuroscience, biotechnology and otologic surgery.

  • Creed Stary

    Creed Stary

    Associate Professor of Anesthesiology, Perioperative and Pain Medicine (Adult MSD) and, by courtesy, of Ophthalmology

    Current Research and Scholarly InterestsMechanisms promoting neuronal survival following cerebral ischemia-reperfusion injury; utilizing microRNA's to target multiple pathways to promote mitochondrial homeostasis and cell survival; anesthetic neurotoxicity; astrocyte-neuronal interaction

  • Kristan Staudenmayer, MD, MS, FACS

    Kristan Staudenmayer, MD, MS, FACS

    Associate Professor of Surgery (General Surgery)

    Current Research and Scholarly InterestsDefining the Impact of Injuries in the Elderly

  • Tim Stearns

    Tim Stearns

    Professor of Biology

    Current Research and Scholarly InterestsWe use the tools of genetics, microscopy, and biochemistry to understand fundamental questions of cell biology: How are cells organized by the cytoskeleton? How do the centrosome and cilium control cell control cell signaling? How is cell division coordinated with duplication of the centrosome, and what goes wrong in cancer cells defective in this coordination?

  • Gary K. Steinberg, MD, PhD

    Gary K. Steinberg, MD, PhD

    Bernard and Ronni Lacroute-William Randolph Hearst Professor of Neurosurgery and Neurosciences and Professor, by courtesy, of Neurology

    Current Research and Scholarly InterestsOur laboratory investigates the pathophysiology and treatment of cerebral ischemia, and methods to restore neurologic function after stroke. Treatment strategies include brain hypothermia, stem cell transplantation and optogenetic stimulation. Our clinical research develops innovative surgical, endovascular and radiosurgical approaches for treating difficult intracranial aneurysms, complex vascular malformations and occlusive disease, including Moyamoya disease, as well as stem cell transplant.

  • Lawrence Steinman, MD

    Lawrence Steinman, MD

    George A. Zimmermann Professor and Professor of Pediatrics

    Current Research and Scholarly InterestsOur laboratory is dedicated to understanding the pathogenesis of autoimmune diseases, particularly multiple sclerosis. We have developed several new therapies for autoimmunity, including some in Phase 2 clinical trials, as well as one approved drug, natalizumab. We have developed microarray technology for detecting autoantibodies to myelin proteins and lipids. We employ a diverse range of molecular and celluar approaches to trying to understand multiple sclerosis.

  • Lars Steinmetz

    Lars Steinmetz

    Dieter Schwarz Foundation Endowed Professor and Professor of Genetics

    Current Research and Scholarly InterestsWe apply diverse genomic approaches to understand how genetic variation affects health and disease by: 1) functional and mechanistic analyses of gene regulation, 2) studies of meiotic recombination and inheritance, 3) analyses of genetic and environmental interactions, and 4) characterization of diseases in human cells and model organisms. We integrate wet lab and computational genomic, transcriptomic, proteomic and metabolic approaches, and develop technologies to enable personalized medicine.

  • David A. Stevens

    David A. Stevens

    Professor of Medicine, Emeritus

    Current Research and Scholarly InterestsImmunology and chemotherapy of human fungal diseases, particularly coccidioidomycosis (Valley Fever) in California and aspergillosis, and the parasitic disease, trypanosomiasis.

  • David Stevenson

    David Stevenson

    Professor of Pediatrics (Genetics)

    Current Research and Scholarly InterestsMy research focuses on disorders of the RAS/MAPK pathway (eg. NF1, Noonan, CFC, and Costello syndrome). I am working on understanding the impact of RAS signaling on the musculoskeletal system. I use genomic approaches to identify somatic events and modifiers in the RASopathies. I am also involved in identifying outcome measures for use in clinical trials for the associated orthopedic manifestations. Other areas of research involve vascular anomalies, Prader-Willi syndrome, and hypophosphatasia.