Bio-X


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  • Yan Xia

    Yan Xia

    Associate Professor of Chemistry

    Current Research and Scholarly InterestsPolymer Chemistry, Microporous Polymer Membranes, Responsive Polymers, Degradable Polymers, Polymers with Unique Mechanical Behaviors, Polymer Networks, Organic Electronic Materials

  • Haopeng Xiao

    Haopeng Xiao

    Assistant Professor of Biochemistry

    BioUnderstanding mechanisms of metabolic regulation in physiology and disease forms the basis for developing therapies to treat diseases in which metabolism is perturbed. We devise novel mass spectrometry (MS)-based proteomics technologies, combined with data science, to systematically discover mechanisms of metabolic regulation over protein function. Our strategies established the first tissue-specific landscape of protein cysteine redox regulation during aging, elucidating mechanisms of redox signaling in physiology that remained elusive for decades. We also leverage the genetic diversity of outbred populations to systematically annotate protein function and protein-metabolite co-regulation. The aim of our research program is to develop next-generation MS-based strategies to understand mechanisms of metabolic regulation in aging, metabolic disease, and cancer, and to use this knowledge as a basis to develop translational therapeutics.

  • Lei Xing

    Lei Xing

    Jacob Haimson and Sarah S. Donaldson Professor and Professor, by courtesy, of Electrical Engineering

    Current Research and Scholarly Interestsartificial intelligence in medicine, medical imaging, Image-guided intervention, molecular imaging, biology guided radiation therapy (BGRT), treatment plan optimization