Wu Tsai Human Performance Alliance
Showing 111-120 of 287 Results
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Ngan F. Huang
Associate Professor of Cardiothoracic Surgery (Cardiothoracic Surgery Research) and, by courtesy, of Chemical Engineering
Current Research and Scholarly InterestsDr. Huang's laboratory aims to understand the chemical and mechanical interactions between extracellular matrix (ECM) proteins and pluripotent stem cells that regulate vascular and myogenic differentiation. The fundamental insights of cell-matrix interactions are applied towards stem cell-based therapies with respect to improving cell survival and regenerative capacity, as well as engineered vascularized tissues for therapeutic transplantation.
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Andrew D. Huberman
Associate Professor of Neurobiology and, by courtesy, of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsIn 2017, we developed a virtual reality platform to investigate the neural and autonomic mechanisms contributing to fear and anxiety. That involved capturing 360-degree videos of various fear-provoking situations in real life for in-lab VR movies, such as heights and claustrophobia, as well as unusual scenarios like swimming in open water with great white sharks. The primary objective of our VR platform is to develop new tools to help people better manage stress, anxiety and phobias in real-time, as an augment to in-clinic therapies.
In May 2018, we reported the discovery of two novel mammalian brain circuits as a Research Article published in Nature. One circuit promotes fear and anxiety-induced paralysis, while the other fosters confrontational reactions to threats. This led to ongoing research into the involvement of these brain regions in anxiety-related disorders such as phobias and generalized anxiety in humans.
In 2020, we embarked on a collaborative effort with Dr. David Spiegel's laboratory in the Stanford Department of Psychiatry and Behavioral Sciences, aimed to explore how specific respiration patterns synergize with the visual system to influence autonomic arousal and stress, and other brain states, including sleep.
In 2023, the first results of that collaboration were published as a randomized controlled trial in Cell Reports Medicine, demonstrating that specific brief patterns of deliberate respiration are particularly effective in alleviating stress and enhancing mood, and improving sleep.
In a 2021, our collaboration with Dr. Edward Chang, professor and chair of the Department of Neurological Surgery at the University of California, San Francisco (UCSF), was published in Current Biology, revealing that specific patterns of insular cortex neural activity may be linked to, and potentially predict, anxiety responses. -
Gentaro Ikeda
Instructor, Medicine - Cardiovascular Medicine
BioDr. Ikeda is a physician-scientist who develops innovative diagnostic and therapeutic modalities for patients with cardiovascular disease. Based on his clinical experience as a cardiologist, he has become aware of major clinical shortcomings, specifically in the current pharmaceutical therapies for myocardial infarction (MI) and chronic heart failure (HF). Some evidence-based drug therapies, including β-blockers, ivabradine, and renin-angiotensin-aldosterone antagonists are difficult to apply to critical patients due to adverse side effects. Drugs that have shown efficacy in basic animal experiments have failed to show significant benefits in clinical trials. To address these problems, he moved to academia to conduct translational research. During his graduate training in the Egashira Lab, he focused on drug delivery systems (DDS) that target mitochondria in animal models of MI. He obtained advanced skills in molecular biology, mitochondrial bioenergetics, and animal surgery. He realized the importance of translational research and the great potential of DDS to overcome many clinical problems. He developed nanoparticle-mediated DDS containing cyclosporine for the treatment of patients with MI. He published a first-author paper and received academic awards for his novel science. Since becoming a postdoctoral fellow in the Yang Lab, he has continued to build upon his previous training in translational research. He is currently developing an innovative therapy, namely, extracellular vesicles-mediated mitochondrial transfer for mitochondria-related diseases such as heart failure and mitochondrial disease.
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Doug James
Professor of Computer Science and, by courtesy, of Music
Current Research and Scholarly InterestsComputer graphics & animation, physics-based sound synthesis, computational physics, haptics, reduced-order modeling
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Deborah Kado
Professor of Medicine (Primary Care and Population Health) and, by courtesy, of Epidemiology and Population Health
BioDr. Kado is a board-certified, fellowship-trained doctor specializing in geriatrics. She serves as co-director of the Stanford Longevity Center. She is a professor of medicine and chief of research for the Geriatrics Section in the Department of Medicine, Division of Primary Care and Population Health. She is also the Director of the Geriatric Research, Education, and Clinical Center (GRECC) at VA Palo Alto Health Care System.
For each patient, Dr. Kado prepares a personalized care plan. Her objective is to help all individuals maintain the best possible health and quality of life as they age.
A special interest of Dr. Kado is bone health. She has conducted extensive research focused on osteoporosis and the related disorder hyperkyphosis.
Since joining the UCLA faculty in 2000, she has received continuous funding for her research from the National Institutes of Health (NIH).
She has over 100 peer-reviewed publications of her research findings in the Journal of Bone and Mineral Research, Osteoporosis International, Journal of Gerontology and Medical Sciences, Journal of Geriatric Oncology, Nature Communications, and other peer-reviewed journals.
In 2007, she defined hyperkyphosis as a new geriatric syndrome. Her discoveries in this field were first featured in the American College or Physician’s premier internal medicine journal Annals of Internal Medicine. Later, they also appeared in a dedicated chapter in UpToDate, the electronic resource providing evidence-based clinical decision support for doctors worldwide.
Prior to coming to Stanford, Dr. Kado practiced at UC San Diego where she started a dedicated osteoporosis clinic for patient care and research. She later broadened her research interests beyond musculoskeletal aging to study other aging-related topics such as the gut microbiome in older men and the effects of cancer treatments on aging in newly diagnosed breast cancer patients.
Dr. Kado is a California native. She trained at UCSF and UCLA. She also earned a Master of Science degree in epidemiology at the UCLA School of Public Health, sponsored by the John Hartford Foundation.
She is a member of the American Geriatrics Society, American Society of Bone and Mineral Research, Gerontological Society of America, The Endocrine Society, and other professional organizations. She co-chairs the NIH National Institute on Aging Workshop for the American Society of Bone and Mineral Research. She also participates in the Bone Health Working Group of the Society for Women’s Health Research. -
Robin Kamal MD MBA
Associate Professor of Orthopaedic Surgery
Current Research and Scholarly InterestsWrist and Elbow Injuries and Quality Measures in Orthopaedic Surgery
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Daniel Katz
Assistant Professor of Medicine (BMIR)
BioDaniel Katz is an Assistant Professor of Medicine in the Stanford Center for Biomedical Informatics Research (BMIR) and the Cardiovascular Medicine Divisions. He practices as an Advanced Heart Failure and Transplant Cardiologist. He completed internal medicine residency at Massachusetts General Hospital, general cardiology training at Beth Israel Deaconess Medical Center, and then joined Stanford in 2021 for his advanced heart failure training. Since medical school, his research has focused on identifying the various pathophysiologic patterns and mechanisms that lead to the heterogeneous syndrome of heart failure. His efforts leverage high dimensional data in many forms including clinical phenotypes, plasma proteomics, metabolomics, and genetics. He is presently engaged in analysis of multi-omic data from the Molecular Transducers of Physical Activity Consortium (MoTrPAC) and the NHLBI Trans-Omics for Precision Medicine (TOPMed) Program. His clinical interests include advanced heart failure, transplant cardiology, and mechanical circulatory support.
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Monroe Kennedy III
Assistant Professor of Mechanical Engineering
Current Research and Scholarly InterestsMy research focus is to develop technology that improves everyday life by anticipating and acting on the needs of human counterparts. My research can be divided into the following sub-categories: robotic assistants, connected devices and intelligent wearables. My Assistive Robotics and Manipulation lab focuses heavily on both the analytical and experimental components of assistive technology design.
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Khizer Khaderi MD, MPH
Clinical Associate Professor, Ophthalmology
BioDr. Khizer Khaderi is a Clinical Associate Professor at the Byers Eye Institute at Stanford University. Khaderi is the Founding Director of the Stanford Human Perception Laboratory (HPL) and the Stanford Vision Performance Center (VPC). He also serves as faculty at the Stanford Institute for Human-Centered AI and the Wu Tsai Human Performance Alliance (HPA)
Khaderi is a renowned Neuro-Ophthalmic surgeon, technologist and futurist. Dr. Khaderi is pioneering the field of Symbiotics, defined as the convergence of human science + computer science. Khaderi developed the discipline of Symbiotics following initial interest from CS students interested in his research at the Stanford Human Perception Lab. Symbiotics involves a deep understanding in the principles of human systems and applying these principles computationally, to design and develop the next generation of human-centric technologies, where machines perceive, understand and respond to optimize the human experience. Dr. Khaderi envisions the application of Symbiotic principles as the key to unlocking ambient intelligence.
Khaderi has extensive domain expertise in artificial intelligence (AI), spatial computing (virtual reality (VR), augmented reality (AR), mixed reality (MxR)), wearables, gaming, IoT, Web3, applied neuroscience, human factors, and human-machine interfaces/interaction. His research interests include developing personalized human intelligent systems based on the human brain and sensory systems, developing technologies to optimize human performance, and combining biological and computational principles to expand our capabilities in research, clinical practice, and everyday life. Dr. Khaderi's approach to advance research interests and develop practical applications for everyday use is building technology, companies and collaborative partnerships across academia and industry.
Dr. Khaderi’s experience across industry sectors include consumer electronics, gaming, retail, life science, sports/Esports health care, Pharma, e-commerce, to name a few. He has developed novel technologies in these areas, and generated multiple invention patents. Selected as a “40 under 40”, he contributed to President Obama’s Council of Advisors on Science and Technology regarding vision technology and the aging population. He also advises multiple companies, venture firms and organizations including the Global Esports Federation, Magic Leap, Riot Games, Intel, Activision, Unity, Epic Games, Google, FB, Microsoft, Apple, NBA, Aerie Pharma, the World Health Organization, and the World Bank.