Showing 1-8 of 8 Results
Jin Hyung Lee
Associate Professor of Neurology, of Neurosurgery and of Bioengineering and, by courtesy, of Electrical Engineering
Current Research and Scholarly InterestsIn vivo visualization and control of neural circuits
Associate Professor of Neurobiology, of Bioengineering and, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly InterestsOur lab applies biochemical and engineering principles to the development of protein-based tools for molecular imaging and gene therapy. Topics of investigation include fluorescent proteins structure and biophysics, fluorescent protein-based biosensors, spatiotemporal analysis of protein translation pathways, chemical control of protein translation, and light-responsive proteins.
Jonathan Z. Long
Assistant Professor of Pathology
Current Research and Scholarly InterestsMy laboratory uses a multidisciplinary approach combining synthetic chemistry, biochemistry, mass spectrometry, and genetics to mine uncharted biochemical space and to discover new metabolite signaling pathways. Our goal is to understand how these new bioactive metabolite pathways control metabolic homeostasis and mammalian physiology. In recent years, we have mapped entire branches of previously unknown bioactive metabolites and identified their functions. These discoveries include a circulating PM20D1/N-acyl amino acid pathway in blood and a MAGL-controlled lipid signaling pathway in the brain. Ultimately, we hope to translate these findings into pharmacologically tractable opportunities (e.g., enzyme inhibitors, transporter antagonists, or receptor modulators) for therapeutic intervention in human disease.
Sharon R. Long
William C. Steere, Jr. - Pfizer Inc. Professor in Biological Sciences and Professor, by courtesy, of Biochemistry
Current Research and Scholarly InterestsBiochemistry, genetics and cell biology of plant-bacterial symbiosis
Deane P. and Louise Mitchell Professor in the School of Medicine and Professor, by courtesy, of Materials Science and Engineering
Current Research and Scholarly InterestsWe have six main areas of current interest: 1) Cranial Suture Developmental Biology, 2)Distraction Osteogenesis, 3) Cleft Palate and Lip Biology, 4)Keloid and Hypertrophic Scar Biology, 5) Scarless Fetal Wound Healing, 6) Novel Gene and Stem Cell Therapeutic Approaches.
Anson Lowe, MD
Associate Professor of Medicine (Gastroenterology and Hepatology)
Current Research and Scholarly InterestsThe laboratory is focused on the relationship between injury, wound healing, and cancer. Esophageal, gastric, and pancreatic cancers are a focus. We are particularly interested in the regulation of cell signaling by EGFR, the EGF receptor. In addition to cancer pathogenesis, active projects include the development of new diagnostic assays and drugs.