Stanford Neurosciences Institute
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Gregory W. Albers, MD
The Coyote Foundation Professor and Professor, by courtesy, of Neurosurgery at the Stanford University Medical Center
Current Research and Scholarly InterestsOur group's research focus is the acute treatment and prevention of cerebrovascular disorders. Our primary interest is the use of advanced imaging techniques to expand the treatment window for ischemic stroke. We are also conducting clinical studies of both neuroprotective and thrombolytic strategies for the treatment of acute stroke and investigating new antithrombotic strategies for stroke prevention.
Professor of Neurology at the Stanford University Medical Center
Current Research and Scholarly InterestsOur research focuses on understanding how immune responses initiate and accelerate synaptic and neuronal injury in age-related neurodegeneration, including models of Alzheimer's disease and Parkinson's disease. We also focus on the role of immune responses in aggravating brain injury in models of stroke. Our goal is the identification of critical immune pathways that function in neurologic disorders and that can be targeted to elicit disease modifying effects.
Ann M. Arvin
Lucile Salter Packard Professor of Pediatrics and Professor of Microbiology and Immunology
Current Research and Scholarly InterestsOur laboratory investigates the pathogenesis of varicella zoster virus (VZV) infection, focusing on the functional roles of particular viral gene products in pathogenesis and virus-cell interactions in differentiated human cells in humans and in Scid-hu mouse models of VZV cell tropisms in vivo, and the immunobiology of VZV infections.
K. K. Lee Professor in the School of Engineering, Senior Fellow at the Precourt Institute for Energy and Professor, by courtesy, of Materials Science and Engineering and of Chemistry
BioZhenan Bao joined Stanford University in 2004. She is currently a K.K. Lee Professor in Chemical Engineering, and with courtesy appointments in Chemistry and Material Science and Engineering. She is a member of the National Academy of Engineering and National Academy of Inventors. She founded the Stanford Wearable Electronics Initiative (eWEAR) and is the current faculty director. She is also an affiliated faculty member of Precourt Institute, Woods Institute, ChEM-H and Bio-X. Professor Bao received her Ph.D. degree in Chemistry from The University of Chicago in 1995 and joined the Materials Research Department of Bell Labs, Lucent Technologies. She became a Distinguished Member of Technical Staff in 2001. Professor Bao currently has more than 400 refereed publications and more than 60 US patents. She served as a member of Executive Board of Directors for the Materials Research Society and Executive Committee Member for the Polymer Materials Science and Engineering division of the American Chemical Society. She was an Associate Editor for the Royal Society of Chemistry journal Chemical Science, Polymer Reviews and Synthetic Metals. She serves on the international advisory board for Advanced Materials, Advanced Energy Materials, ACS Nano, Accounts of Chemical Reviews, Advanced Functional Materials, Chemistry of Materials, Chemical Communications, Journal of American Chemical Society, Nature Asian Materials, Materials Horizon and Materials Today. She is one of the Founders and currently sits on the Board of Directors of C3 Nano Co. and PyrAmes, bot are silicon valley venture funded companies. She is Fellow of AAAS, ACS, MRS, SPIE, ACS POLY and ACS PMSE. She was a recipient of the L'Oreal UNESCO Women in Science Award in 2017. She was awarded the ACS Applied Polymer Science Award in 2017, ACS Creative Polymer Chemistry Award in 2013 ACS Cope Scholar Award in 2011, and was selected by Phoenix TV, China as 2010 Most influential Chinese in the World-Science and Technology Category. She is a recipient of the Royal Society of Chemistry Beilby Medal and Prize in 2009, IUPAC Creativity in Applied Polymer Science Prize in 2008, American Chemical Society Team Innovation Award 2001, R&D 100 Award, and R&D Magazine Editors Choice Best of the Best new technology for 2001. She has been selected in 2002 by the American Chemical Society Women Chemists Committee as one of the twelve Outstanding Young Woman Scientist who is expected to make a substantial impact in chemistry during this century. She is also selected by MIT Technology Review magazine in 2003 as one of the top 100 young innovators for this century. She has been selected as one of the recipients of Stanford Terman Fellow and has been appointed as the Robert Noyce Faculty Scholar, Finmeccanica Faculty Scholar and David Filo and Jerry Yang Faculty Scholar.
Assistant Professor of Genetics
Current Research and Scholarly InterestsMy laboratory is focused on (1) the development of new technologies for high-throughput functional genomics using the CRISPR/Cas9 system, and (2) application of these tools to study the cellular response to drugs and endocytic pathogens (such as bacteria, viruses, and protein toxins). Fascinating in themselves, these pathogens also help illuminate basic cell biology. A complementary interest is in the identification of new drug targets and combinations to combat cancer and neurodegeneration.
Associate Professor of Developmental Biology, of Computer Science, of Biomedical Data Science and of Pediatrics (Genetics)
Current Research and Scholarly InterestsDr. Bejerano, co-discoverer of ultraconserved elements, studies the Human Genome. His research focuses on genome sequence and function in both humans and related primate, mammalian and vertebrate species. He is deeply interested in mapping both coding and non-coding genome sequence variation to phenotype differences, and in extracting specific genetic insights from high throughput sequencing measurements, in the contexts of development and developmental abnormalities.
Assistant Professor (Research) of Pathology
Current Research and Scholarly InterestsOur goal is to understand the mechanisms regulating the development of human systems. Drawing on both pluripotent stem cell biology, hematopoiesis, and immunology, combined with novel high-content single-cell analysis (CyTOF – Mass Cytometry) and imagining (MIBI-Multiplexed Ion Beam Imaging) we are creating templates of ‘normal’ human cellular behavior to both discover novel regulatory events and cell populations as well as understand dysfunctional processes such as cancer.
Denning Family Provostial Professor
BioJonathan Berger is the Denning Family Provostial Professor in Music at Stanford University, where he teaches composition, music theory, and cognition at the Center for Computer Research in Music and Acoustics (CCRMA).
Jonathan is a 2017 Guggenheim Fellow and a 2016 winner of the Rome Prize.
He was the founding co-director of the Stanford Institute for Creativity and the Arts (SICA, now the Stanford Arts Institute) and founding director of Yale University’s Center for Studies in Music Technology
Described as “gripping” by both the New York Times and the Chicago Tribune, “poignant”, “richly evocative” (San Francisco Chronicle), “taut, and hauntingly beautiful” (NY Times), Jonathan Berger’s recent works deal with both consciousness and conscience. The Kronos Quartet toured recent monodrama, My Lai internationally. Thrice commissioned by The National Endowment for the Arts, Berger’a recent commissions include The Mellon and Rockefeller Foundations, Chamber Music Society, Lincoln Center, and Chamber Music America. Upcoming commissions include an oratorio entitled The Ritual of Breath, and Leonardo, for baritone and chamber orchestra.
In addition to composition, Berger is an active researcher with over 80 publications in a wide range of fields relating to music, science and technology and has held research grants from DARPA, the Wallenberg Foundation, The National Academy of Sciences, the Keck Foundation, and others.
Assistant Professor of Psychiatry and Behavioral Sciences (Public Mental Health and Population Sciences)
BioDr. Bernert is Founding Director of the Suicide Prevention Research Laboratory, and Co-Chairs a special departmental initiative to develop a Center for Premature Mortality and Suicide Prevention. She is a suicidologist, with subspecialty expertise in suicide prevention clinical trials, standardized suicide risk assessment and best practice management, and the epidemiology of self-directed violence. She has subspecialty training in behavioral sleep medicine, with a background in sleep and circadian physiology. Her program utilizes cognitive, biologic (e.g., fMRI), and behavioral testing paradigms, with an emphasis on translational therapeutics. Dr. Bernert has collaborated with NIH, DOD, DARPA, SAMHSA, and CDC on suicide prevention initiatives; and recently served as a content expert for the White House 2015 Open Data and Innovation for Suicide Prevention #Hackathon. She has also contributed to the development of clinical practice parameters, including the 2013 VA/DOD Clinical Practice Guidelines for the Assessment and Management of Suicide Risk, with current work underway focused on investigating medical education training in suicide risk assessment and management. Her research focuses on the identification of novel therapeutic targets for suicide prevention across the lifespan, particularly those aiming to reduce stigma and enhance access to care. A specific focus of this work emphasizes the use of rapid-action, low-risk treatment approaches for the prevention of suicide. Dr. Bernert has several suicide prevention trials underway, funded by NIH and DOD, testing the preliminary efficacy of a non pharmacological insomnia treatment on suicidal behaviors. She also has several grants focused on the development of a data monitoring system for the study of local suicide clusters and emergency department based protocols to improve risk detection within pediatric suicide prevention. Our aim is to delineate transdiagnostic risk factors and biomarkers of clinical response that may inform the pathogenesis of risk and treatment innovation. An overarching mission is to harness new technologies within suicide prevention, including artificial intelligence (AI) and mobile health applications, to enhance risk detection and multidisciplinary frameworks. Advisory and advocacy work, and the way in which research guides health policy, dissemination, and national strategies for suicide prevention, represents an extension of this work. This includes recent initiatives to establish national and local guidelines for lethal means restriction and calls for advanced technology use in suicide prevention research and strategy. Last, Dr. Bernert has several pilot projects underway focused on inclusive practices in faculty diversity and development, and the way in which family-friendly policies impact faculty recruitment and retention in academic medicine.
Anne T. and Robert M. Bass Professor in the School of Humanities and Sciences and Professor, by courtesy, of Radiology and of Chemical and Systems Biology
BioProfessor Carolyn Bertozzi's research interests span the disciplines of chemistry and biology with an emphasis on studies of cell surface sugars important to human health and disease. Her research group profiles changes in cell surface glycosylation associated with cancer, inflammation and bacterial infection, and uses this information to develop new diagnostic and therapeutic approaches, most recently in the area of immuno-oncology.
Dr. Bertozzi completed her undergraduate degree in Chemistry at Harvard University and her Ph.D. at UC Berkeley, focusing on the chemical synthesis of oligosaccharide analogs. During postdoctoral work at UC San Francisco, she studied the activity of endothelial oligosaccharides in promoting cell adhesion at sites of inflammation. She joined the UC Berkeley faculty in 1996. A Howard Hughes Medical Institute Investigator since 2000, she came to Stanford University in June 2015, among the first faculty to join the interdisciplinary institute ChEM-H (Chemistry, Engineering & Medicine for Human Health). Named a MacArthur Fellow in 1999, Dr. Bertozzi has received many awards for her dedication to chemistry, and to training a new generation of scientists fluent in both chemistry and biology. She has been elected to the Institute of Medicine, National Academy of Sciences, and American Academy of Arts and Sciences; and received the Lemelson-MIT Prize, the Heinrich Wieland Prize, and the ACS Award in Pure Chemistry, among many others. Her efforts in undergraduate education have earned the UC Berkeley Distinguished Teaching Award and the Donald Sterling Noyce Prize for Excellence in Undergraduate Teaching.
Today, the Bertozzi Group at Stanford studies the glycobiology underlying diseases such as cancer, inflammatory disorders such as arthritis, and infectious diseases such as tuberculosis. The work has advanced understanding of cell surface oligosaccharides involved in cell recognition and inter-cellular communication.
Dr. Bertozzi's lab also develops new methods to perform controlled chemical reactions within living systems. The group has developed new tools for studying glycans in living systems, and more recently nanotechnologies for probing biological systems. Such "bioorthoganol" chemistries enable manipulation of biomolecules in their living environment.
Several of the technologies developed in the Bertozzi lab have been adapted for commercial use. Actively engaged with several biotechnology start-ups, Dr. Bertozzi founded Redwood Bioscience of Emeryville, California, and has served on the research advisory board of GlaxoSmithKline.
Sandip Biswal, MD
Associate Professor of Radiology (Musculoskeletal Imaging) at the Stanford University Medical Center
Current Research and Scholarly InterestsThe management of individuals suffering from chronic pain is unfortunately limited by poor diagnostic tests and therapies. Our research group is interested in 'imaging pain' by using novel imaging techniques to study peripheral nociception and inflammation with the goal of accurately identifying the location of pain generators. We are developing new approaches with positron emission tomography (PET) and magnetic resonance imaging (MRI) (PET/MRI) and are currently in clinical trials.
Helen M. Blau
The Donald E. and Delia B. Baxter Foundation Professor and Director, Baxter Laboratory for Stem Cell Biology
Current Research and Scholarly InterestsProf. Helen Blau's research area is regenerative medicine with a focus on stem cells. Her research on nuclear reprogramming and demonstrating the plasticity of cell fate using cell fusion is well known and her laboratory has also pioneered the design of biomaterials to mimic the in vivo microenvironment and direct stem cell fate. Current findings are leading to more efficient iPS generation, cell based therapies by dedifferentiation a la newts, and discovery of novel molecules and therapies.
Nikolas Blevins, MD
Larry and Sharon Malcolmson Professor in the School of Medicine and Professor, by courtesy, of Neurosurgery at the Stanford University Medical Center
Current Research and Scholarly InterestsInner ear microendoscopy -- Developing techniques for minimally-invasive imaging of inner ear microanatomy and neural pysiology. Applications include improved cochlear implant development, inner ear regenerative techniques, inner ear surgery, and auditory physiology.
Microsurgical robotics -- Developing scalable microsurgical instrumentation and robotic techniques for use in head and neck surgery.
Surgical Simulation -- Immersive environment for temporal bone surgical simulation.
Professor of Bioengineering and of Electrical Engineering
Current Research and Scholarly InterestsLarge-scale models of sensory, perceptual and motor systems
Assistant Professor of Psychiatry and Behavioral Sciences (Child and Adolescent Psychiatry and Development) at the Stanford University Medical Center
Current Research and Scholarly InterestsMy research interests have focused on the neural bases of eating disorders and obesity. I am particularly interested in the way emotion and reward is processed in the brain and how that may contribute to eating behavior and food restriction. I hope to eventually translate biological research findings into treatments.
Assistant Professor of Medicine (Infectious Diseases) and of Microbiology and Immunology
Current Research and Scholarly InterestsOur lab studies how immune responses are regulated within chronically inflamed or infected tissues. In particular, we study how the extracellular matrix influences local immunity and why these responses are dysregulated in autoimmune diseases, poorly healing wounds, and chronic infections.
We welcome research students with interests in immunology, structural biology, and microbiology.
Steven G. Boxer
Camille Dreyfus Professor of Chemistry
Current Research and Scholarly InterestsPlease visit my website for complete information:
Professor of Materials Science and Engineering and, by courtesy, of Applied Physics
BioMark Brongersma is a Professor in the Department of Materials Science and Engineering at Stanford University. He received his PhD in Materials Science from the FOM Institute in Amsterdam, The Netherlands, in 1998. From 1998-2001 he was a postdoctoral research fellow at the California Institute of Technology. During this time, he coined the term “Plasmonics” for a new device technology that exploits the unique optical properties of nanoscale metallic structures to route and manipulate light at the nanoscale. His current research is directed towards the development and physical analysis of nanostructured materials that find application in nanoscale electronic and photonic devices. Brongersma received a National Science Foundation Career Award, the Walter J. Gores Award for Excellence in Teaching, the International Raymond and Beverly Sackler Prize in the Physical Sciences (Physics) for his work on plasmonics, and is a Fellow of the Optical Society of America, the SPIE, and the American Physical Society.
Helen Bronte-Stewart, MD, MS
John E. Cahill Family Professor, Professor of Neurology and, by courtesy, of Neurosurgery at the Stanford University Medical Center
Current Research and Scholarly InterestsMy research focus is human motor control and brain pathophysiology in movement disorders. Our overall goal is to understand the role of the basal ganglia electrical activity in the pathogenesis of movement disorders. We have developed novel computerized technology to measure fine, limb and postural movement. With these we are measuring local field potentials in basal ganglia nuclei in patients with Parkinson's disease and dystonian and correlating brain signalling with motor behavior.
Michele and Timothy Barakett Endowed Professor
Current Research and Scholarly InterestsOur lab studies the molecular basis of longevity. We are interested in the mechanism of action of known longevity genes, including FOXO and SIRT, in the mammalian nervous system. We are particularly interested in the role of these longevity genes in neural stem cells. We are also discovering novel genes and processes involved in aging using two short-lived model systems, the invertebrate C. elegans and an extremely short-lived vertebrate, the African killifish N. furzeri.
Professor of Molecular and Cellular Physiology, of Neurology, of Photon Science and, by courtesy, of Structural Biology
Current Research and Scholarly InterestsOne of Axel Brunger's major goals is to decipher the molecular mechanisms of synaptic neurotransmitter release by conducting imaging and single-molecule/particle reconstitution experiments, combined with near-atomic resolution structural studies of the synaptic vesicle fusion machinery.
Associate Professor of Bioengineering and, by courtesy, of Structural Biology
Current Research and Scholarly InterestsMolecular motors lie at the heart of biological processes from DNA replication to vesicle transport. My laboratory seeks to understand the physical mechanisms by which these nanoscale machines convert chemical energy into mechanical work.
Paul Buckmaster, DVM, PhD
Professor of Comparative Medicine and of Neurology
Current Research and Scholarly InterestsMechanisms of epilepsy, especially temporal lobe epilepsy.
Marion S. Buckwalter, MD, PhD
Associate Professor of Neurology and of Neurosurgery at the Stanford University Medical Center
Current Research and Scholarly InterestsThe goal of the Buckwalter Lab is to improve how people recover after a stroke. We use basic research to understand the cells, proteins, and genes that lead to successful recovery of function, and also how complications develop that impact quality of life after stroke. Ongoing projects are focused on understanding how inflammatory responses are regulated after a stroke and how to make recovery faster and better after stroke.
Klaus Bensch Professor in Pathology
Current Research and Scholarly InterestsOur interests include:
1) The physiology and function of lymphocyte homing in local and systemic immunity;
2) Biochemical and genetic studies of molecules that direct leukocyte recruitment;
3) Chemotactic mechanisms and receptors in vascular and immune biology;
4) Vascular control of normal and pathologic inflammation and immunity;
5) Systems biology of immune cell trafficking and programming in tumor immunity.
Assistant Professor of Bioengineering and, by courtesy, of Neurosurgery and of Mechanical Engineering
Current Research and Scholarly InterestsThe Camarillo Lab is currently instrumenting Stanford athletes with inertial sensors to investigate the mechanism of concussion. Additionally, the lab is researching cell mechanics for regenerative medicine. We are developing a quantitative, noninvasive and early measure of viability in order to allow clinicians to transfer the single most viable embryo. Other research area is in medical instrumentation as it pertains to robotic catheterization for curing cardiac arrhythmia.
Victor G. Carrion
John A. Turner Endowed Professor for Child and Adolescent Psychiatry
Current Research and Scholarly InterestsExamines the interplay between brain development and stress vulnerability via a multi-method approach that includes psychophysiology, neuroimaging, neuroendocrinology and phenomenology. Treatment development that focuses on individual and community-based interventions for stress related conditions in children and adolescents that experience traumatic stress.
Director, Stanford Center on Longevity and the Fairleigh S. Dickinson, Jr. Professor in Public Policy
BioLaura L. Carstensen is Professor of Psychology at Stanford University where she is the Fairleigh S. Dickinson Jr. Professor in Public Policy and founding director of the Stanford Center on Longevity. For more than twenty-five years her research has been supported by the National Institute on Aging and during that period she was honored with two MERIT awards. Her most current empirical research focuses on ways in which motivational changes influence cognitive processing. Dr. Carstensen is a fellow in the Association for Psychological Science, the American Psychological Association and the Gerontological Society of America. She was a member of the MacArthur Foundation’s Research Network on an Aging Society and served on the National Advisory Council on Aging to National Institute on Aging. Carstensen has won numerous awards, including the Kleemeier Award, The Richard Kalish Award for Innovative Research and the Distinguished Mentorship Award from the Gerontological Society of America, as well as the Master Mentor Award from the American Psychological Association. She was selected as a Guggenheim Fellow in 2003 and in 2016 was inducted into the National Academy of Medicine. In 2011, she authored A Long Bright Future: Happiness, Health, and Financial Security in an Age of Increased Longevity. Carstensen received her B.S. from the University of Rochester and her Ph.D. in Clinical Psychology from West Virginia University. She holds an honorary doctorate from the Katholieke Universiteit Leuven, Belgium.
Duca Family Professor
BioChris Chafe is a composer, improvisor and cellist, developing much of his music alongside computer-based research. He is Director of Stanford University's Center for Computer Research in Music and Acoustics (CCRMA). At IRCAM (Paris) and The Banff Centre (Alberta), he pursued methods for digital synthesis, music performance and real-time internet collaboration. CCRMA's SoundWIRE project involves live concertizing with musicians the world over. Online collaboration software including jacktrip and research into latency factors continue to evolve. An active performer either on the net or physically present, his music reaches audiences in dozens of countries and sometimes at novel venues. A simultaneous five-country concert was hosted at the United Nations in 2009. Chafe's works are available from Centaur Records and various online media. Gallery and museum music installations are into their second decade with "musifications" resulting from collaborations with artists, scientists and MD's. Recent works include Tomato Quintet for the transLife:media Festival at the National Art Museum of China, Phasor for contrabass and Sun Shot played by the horns of large ships in the port of St. Johns, Newfoundland. Chafe premiered DiPietro's concerto, Finale, for electric cello and orchestra in 2012.
Pak H. Chan
The James R. Doty Professor in Neurosurgery and Neurosciences, Emeritus
Current Research and Scholarly InterestsNeuronal death and regeneration after strokeand neural injury
Howard Y. Chang, MD PhD
Virginia and D. K. Ludwig Professor of Cancer Genomics and of Genetics
Current Research and Scholarly InterestsOur research is focused on how the activities of hundreds or even thousands of genes (gene parties) are coordinated to achieve biological meaning. We have pioneered methods to predict, dissect, and control large-scale gene regulatory programs; these methods have provided insights into human development, cancer, and aging.
Professor of Otolaryngology - Head and Neck Surgery (Pediatrics) at the Stanford University Medical Center and, by courtesy, of Pediatrics at the Lucile Salter Packard Children's Hospital
Current Research and Scholarly Interestshttp://med.stanford.edu/ohns/research/labs_chang.html
Steven D. Chang, MD
Robert C. and Jeannette Powell Neurosciences Professor and, by courtesy, of Otolaryngology-Head and Neck Surgery
Current Research and Scholarly InterestsClinical research includes studies in the treatment of cerebrovascular disorders, such as aneurysms and AVMs, as well as the use of radiosurgery to treat tumors and vascular malformations of the brain and spine.
Dr. Chang is C0-Director of the Cyberknife Radiosurgery Program.
Dr. Chang is also the head of the The Stanford Neuromolecular Innovation Program with the goal of developing new technologies to improve the diagnosis and treatment of patients affected by neurological conditions.
James K. Chen
Professor of Chemical and Systems Biology and of Developmental Biology and, by courtesy, of Chemistry
Current Research and Scholarly InterestsOur laboratory combines synthetic chemistry and developmental biology to investigate the molecular events that regulate embryonic patterning, tissue regeneration, and tumorigenesis. We are currently using genetic and small-molecule approaches to study the molecular mechanisms of Hedgehog signaling, and we are developing chemical technologies to perturb and observe the genetic programs that underlie vertebrate development.
Professor of Neurosurgery and of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsWhat distinguishes us humans from other animals is our ability to undergo complex behavior. The synapses are the structural connection between neurons that mediates the communication between neurons, which underlies our various cognitive function. My research program aims to understand the cellular and molecular mechanisms that underlie synapse function during behavior in the developing and mature brain, and how synapse function is altered during mental retardation.
Assistant Professor of Biology
Current Research and Scholarly InterestsOur goal is to understand how brain circuits mediate motivated behaviors, and how maladaptive changes in these circuits cause mood disorders. To achieve this goal, we focus on studying the neural circuits for pain and addiction, as both trigger highly motivated behaviors, whereas, transitioning from acute to chronic pain or from recreational to compulsive drug use involves maladaptive changes of the underlying neuronal circuitry.
Alan G. Cheng
Associate Professor of Otolaryngology - Head and Neck Surgery (Pediatrics) and, by courtesy, of Pediatrics
Current Research and Scholarly InterestsActive Wnt signaling maintains somatic stem cells in many organ systems. Using Wnt target genes as markers, we have characterized distinct cell populations with stem cell behavior in the inner ear, an organ thought to be terminally differentiated. Ongoing work focuses on delineating the developing significance of these putative stem/progenitor cells and their behavior after damage.
John R. Adler Professor, Professor of Neurosurgery and of Ophthalmology and, by courtesy, of Electrical Engineering
Current Research and Scholarly InterestsFunctional circuitry of the retina and design of retinal prostheses
Frederick T. Chin, Ph.D.
Assistant Professor (Research) of Radiology (Molecular Imaging)
Current Research and Scholarly InterestsOur group's primary objectives are:
1) Novel radioligand and radiotracer development.
We will develop novel PET (Positron Emission Tomography) imaging agents with MIPS and Stanford faculty as well as other outside collaborations including academia and pharmaceutical industry. Although my personal research interests will be to discover and design of candidate probes that target molecular targets in the brain, our group focus will primarily be on cancer biology and gene therapy. In conjunction with our state-of-the-art imaging facility, promising candidates will be evaluated by PET-CT/MR imaging in small animals and primates. Successful radioligands and/or radiotracers will be extended towards future human clinical applications.
2) Designing new radiolabeling techniques and methodologies.
We will aim to design new radiolabeling techniques and methodologies that may have utility for future radiopharmaceutical development in our lab and the general radiochemistry community.
3) Radiochemistry production of routine clinical tracers.
Since we also have many interests with many Stanford faculty and outside collaborators, our efforts will also include the routine radiochemistry production of many existing radiotracers for human and non-human use. Our routine clinical tracers will be synthesized in custom-made or commercial synthetic modules (i.e. GE TRACERlab modules) housed in lead-shielded cells and be distributed manually or automatically (i.e. Comecer Dorothea) to our imagers.
Professor of Photon Science, Bioengineering and of Microbiology and Immunology
Current Research and Scholarly InterestsMy research include methodology improvements in single particle cryo-EM for atomic resolution structure determination of molecules and molecular machines, as well as in cryo-ET of cells and organelles towards subnanometer resolutions. We have collaborations with many researchers around the country and outside USA on understanding biological processes such as protein folding, virus assembly and disassembly, pathogen-host interactions, signal transduction, transport across cytosol and membrane.
William R. Kenan Jr. Professor and Professor of Molecular and Cellular Physiology
Current Research and Scholarly InterestsSynthesis, functionalization and applications of nanoparticle bioprobes for molecular cellular in vivo imaging in biology and biomedicine. Linear and nonlinear difference frequency mixing ultrasound imaging. Lithium metal-sulfur batteries, new approaches to electrochemical splitting of water. CO2 reduction, lithium extraction from salt water
Shooter Family Professor
Current Research and Scholarly InterestsThe Clandinin lab focuses on understanding how neuronal circuits assemble and function to perform specific computations and guide behavior. Taking advantage of a rich armamentarium of genetic tools available in the fruit fly, combined with imaging, physiology and analytical techniques drawn from systems neuroscience, we examine a variety of visual circuits.
Professor of Anesthesiology, Perioperative and Pain Medicine at the Palo Alto Veterans Affairs Health Care System
BioAfter completion of training I came to Stanford University in 1998. Since that time I have been involved in a number of clinical and research activities. I oversee the Pain Service at the Palo Alto VA hospital where I am involved in the care of patients with both acute and chronic pain. I am active both in the clinic and on a number of committees dedicated to improving pain management for veterans. Much of my remaining time is spent supervising a research laboratory. There we are pursuing several projects related to the questions of why pain sometimes becomes chronic after injuries and why opioids lose their effectiveness over time when used to treat chronic pain. We would like to find ways to maximize functional recovery after surgery and other forms of trauma while minimizing the risks of analgesic use. This work involves local, national and international collaborations.
Richard Lyman Professor in the Humanities, Emerita
BioI am interested in first language acquisition, the acquisition of meaning, acquisitional principles in word-formation compared across children and languages, and general semantic and pragmatic issues in the lexicon and in language use. I am currently working on the kinds of pragmatic information adults offer small children as they talk to them, and on children's ability to make use of this information as they make inferences about unfamiliar meanings and about the relations between familiar and unfamiliar words. I am interested in the inferences children make about where to 'place' unfamiliar words, how they identify the relevant semantic domains, and what they can learn about conventional ways to say things based on adult responses to child errors during acquisition. All of these 'activities' involve children and adults placing information in common ground as they interact. Another current interest of mine is the construction of verb paradigms: how do children go from using a single verb form to using forms that contrast in meaning -- on such dimensions as person, number, and tense? How do they learn to distinguish the meanings of homophones? To what extent do they make use of adult input to discern the underlying structure of the system?
Jennifer R. Cochran
Shriram Chair of Bioengineering, Professor of Bioengineering and, by courtesy, of Chemical Engineering
Current Research and Scholarly InterestsMolecular Engineering, Protein Biochemistry, Biotechnology, Cell and Tissue Engineering, Molecular Imaging, Chemical Biology