School of Engineering


Showing 1-72 of 72 Results

  • Russ B. Altman

    Russ B. Altman

    Kenneth Fong Professor and Professor of Bioengineering, of Genetics, of Medicine (General Medical Discipline), of Biomedical Data Science and, by courtesy, of Computer Science

    Current Research and Scholarly InterestsI refer you to my web page for detailed list of interests, projects and publications. In addition to pressing the link here, you can search "Russ Altman" on http://www.google.com/

  • Annelise E. Barron

    Annelise E. Barron

    Associate Professor of Bioengineering

    Current Research and Scholarly InterestsBiophysical mechanisms of host defense peptides (a.k.a. antimicrobial peptides) and their peptoid mimics; also, molecular and cellular biophysics of human innate immune responses.

  • Lacramioara Bintu

    Lacramioara Bintu

    Assistant Professor of Bioengineering

    BioLacra Bintu is an Assistant Professor in the Bioengineering Department at Stanford. Her lab performs single-cell measurements of chromatin and gene regulation dynamics, and uses these data to develop predictive models of basic biological processes and improve mammalian cell engineering.

    Lacra started working on the theory of gene regulation as an undergraduate with Jané Kondev from Brandeis University and Rob Phillips from Caltech. As a Physics PhD student in the lab of Carlos Bustamante at U.C. Berkeley, she used single-molecule methods to tease apart the molecular mechanisms of transcription through nucleosomes. She transitioned to studying the dynamics of epigenetic regulation in live cells during her postdoctoral fellowship with Michael Elowitz at Caltech. She started her own interdisciplinary lab at Stanford in January 2017.

  • Kwabena Boahen

    Kwabena Boahen

    Professor of Bioengineering, of Electrical Engineering and, by courtesy, of Computer Science

    Current Research and Scholarly InterestsLarge-scale models of sensory, perceptual and motor systems

  • Zev Bryant

    Zev Bryant

    Associate Professor of Bioengineering and, by courtesy, of Structural Biology

    Current Research and Scholarly InterestsMolecular motors lie at the heart of biological processes from DNA replication to vesicle transport. My laboratory seeks to understand the physical mechanisms by which these nanoscale machines convert chemical energy into mechanical work.

  • David Camarillo

    David Camarillo

    Associate Professor of Bioengineering
    On Leave from 10/01/2020 To 12/31/2020

    BioDavid B. Camarillo is Assistant Professor of Bioengineering, (by courtesy) Mechanical Engineering and Neurosurgery at Stanford University. Dr. Camarillo holds a B.S.E in Mechanical and Aerospace Engineering from Princeton University, a Ph.D. in Mechanical Engineering from Stanford University and completed postdoctoral fellowships in Biophysics at the UCSF and Biodesign Innovation at Stanford. Dr. Camarillo worked in the surgical robotics industry at Intuitive Surgical and Hansen Medical, before launching his laboratory at Stanford in 2012. His current research focuses on precision human measurement for multiple clinical and physiological areas including the brain, heart, lungs, and reproductive system. Dr. Camarillo has been awarded the Hellman Fellowship, the Office of Naval Research Young Investigator Program award, among other honors including multiple best paper awards in brain injury and robotic surgery. His research has been funded by the NIH, NSF, DoD, as well as corporations and private philanthropy. His lab’s research has been featured on NPR, the New York Times, The Washington Post, Science News, ESPN, and TED.com as well as other media outlets aimed at education of the public.

  • Wah Chiu

    Wah Chiu

    Wallenberg-Bienenstock Professor and Professor of Bioengineering and of Microbiology and Immunology

    Current Research and Scholarly InterestsMy research includes methodology improvements in single particle cryo-EM for atomic resolution structure determination of molecules and molecular machines, as well as in cryo-ET of cells and organelles towards subnanometer resolutions. We collaborate with many researchers around the country and outside the USA on understanding biological processes such as protein folding, virus assembly and disassembly, pathogen-host interactions, signal transduction, and transport across cytosol and membranes.

  • Jennifer R. Cochran

    Jennifer R. Cochran

    Shriram Chair of Bioengineering, Professor of Bioengineering and, by courtesy, of Chemical Engineering

    Current Research and Scholarly InterestsMolecular Engineering, Protein Biochemistry, Biotechnology, Cell and Tissue Engineering, Molecular Imaging, Chemical Biology

  • Markus Covert

    Markus Covert

    Professor of Bioengineering and, by courtesy, of Chemical and Systems Biology

    Current Research and Scholarly InterestsOur focus is on building computational models of complex biological processes, and using them to guide an experimental program. Such an approach leads to a relatively rapid identification and validation of previously unknown components and interactions. Biological systems of interest include metabolic, regulatory and signaling networks as well as cell-cell interactions. Current research involves the dynamic behavior of NF-kappaB, an important family of transcription factors.

  • Bruce Daniel

    Bruce Daniel

    Professor of Radiology (Body Imaging) and, by courtesy, of Bioengineering

    Current Research and Scholarly Interests1. MRI of Breast Cancer, particularly new techniques. Currently being explored are techniques including ultra high spatial resolution MRI and contrast-agent-free detection of breast tumors.

    2. MRI-guided interventions, especially MRI-compatible remote manipulation and haptics

    3. Medical Mixed Reality. Currently being explored are methods of fusing patients and their images to potentially improve breast conserving surgery, and other conditions.

  • Karl Deisseroth

    Karl Deisseroth

    D. H. Chen Professor, Professor of Bioengineering and of Psychiatry and Behavioral Sciences

    Current Research and Scholarly InterestsResearch in Dr. Deisseroth's laboratory focuses on developing optical, molecular and cellular tools to observe, perturb, and re-engineer brain circuits. His laboratory is based in the James H. Clark Center at Stanford and has developed optogenetic and tissue engineering methods, employing techniques spanning electrophysiology, molecular biology, optics, neural activity imaging, animal behavior, and computational neural network modeling.

  • Scott L. Delp, Ph.D.

    Scott L. Delp, Ph.D.

    James H. Clark Professor in the School of Engineering, Professor of Bioengineering, of Mechanical Engineering and, by courtesy, of Orthopaedic Surgery

    Current Research and Scholarly InterestsExperimental and computational approaches to study human movement. Development of biomechanical models to analyze muscle function, study movement abnormalities, design new medical products, and guide surgery. Imaging technology development including MRI and microendoscopy. Biomedical technology development.

  • Drew Endy

    Drew Endy

    Associate Professor of Bioengineering

    Current Research and Scholarly InterestsWe work to strengthen the foundations and expand the frontiers of synthetic biology. Our foundational work includes (i) advancing reliable reuse of bio-measurements and -materials via standards that enable coordination of labor, and (ii) developing and integrating measurement and modeling tools for representing and analyzing living matter at whole-cell scales. Our work beyond the frontiers of current practice includes (iii) bootstrapping biotechnology tools in unconventional organisms (e.g., mealworms, wood fungus, skin microbes), and (iv) exploring the limits of whole-genome recoding and building cells from scratch. We also support strategy and policy work related to bio-safety, security, economy, equity, justice, and leadership.

  • Jeffrey A. Feinstein, MD, MPH

    Jeffrey A. Feinstein, MD, MPH

    Dunlevie Family Professor of Pulmonary Vascular Disease and Professor, by courtesy, of Bioengineering at the Lucile Salter Packard Children's Hospital

    Current Research and Scholarly InterestsResearch interests include (1) computer simulation and modeling of cardiovascular physiology with specific attention paid to congenital heart disease and its treatment, (2) the evaluation and treatment of pulmonary hypertension/pulmonary vascular diseases, and (3) development and testing of medical devices/therapies for the treatment of congenital heart disease and pulmonary vascular diseases.

  • Michael Fischbach

    Michael Fischbach

    Associate Professor of Bioengineering and of Medicine (Microbiology and Immunology)

    BioMichael Fischbach is an Associate Professor in the Department of Bioengineering at Stanford University, an institute scholar of Stanford ChEM-H, and the director of the Stanford Microbiome Therapies Initiative. Fischbach is a recipient of the NIH Director's Pioneer and New Innovator Awards, an HHMI-Simons Faculty Scholars Award, a Fellowship for Science and Engineering from the David and Lucille Packard Foundation, a Medical Research Award from the W.M. Keck Foundation, a Burroughs Wellcome Fund Investigators in the Pathogenesis of Infectious Disease award, and a Glenn Award for Research in Biological Mechanisms of Aging. His laboratory uses a combination of genomics and chemistry to identify and characterize small molecules from microbes, with an emphasis on the human microbiome. Fischbach received his Ph.D. as a John and Fannie Hertz Foundation Fellow in chemistry from Harvard in 2007, where he studied the role of iron acquisition in bacterial pathogenesis and the biosynthesis of antibiotics. After two years as an independent fellow at Massachusetts General Hospital, Fischbach joined the faculty at UCSF, where he founded his lab before moving to Stanford in 2017. Fischbach is a co-founder and director of Federation Bio, a co-founder of Revolution Medicines, and a member of the scientific advisory board of NGM Biopharmaceuticals.

  • Polly Fordyce

    Polly Fordyce

    Assistant Professor of Bioengineering and of Genetics

    Current Research and Scholarly InterestsThe Fordyce Lab is focused on developing new instrumentation and assays for making quantitative, systems-scale biophysical measurements of molecular interactions. Current research in the lab is focused on three main platforms: (1) arrays of valved reaction chambers for high-throughput protein expression and characterization, (2) spectrally encoded beads for multiplexed bioassays, and (3) sortable droplets and microwells for single-cell assays.

  • Stuart Goodman, MD, PhD

    Stuart Goodman, MD, PhD

    The Robert L. and Mary Ellenburg Professor in Surgery and Professor, by courtesy, of Bioengineering

    Current Research and Scholarly InterestsAs an academic orthopaedic surgeon, my interests center on adult reconstructive surgery, arthritis surgery, joint replacement, biomaterials, biocompatibility, tissue engineering, mesenchymal stem cells. Collaborative clinical, applied and basic research studies are ongoing.

  • Brian A. Hargreaves

    Brian A. Hargreaves

    Professor of Radiology (Radiological Sciences Laboratory) and, by courtesy, of Electrical Engineering and of Bioengineering

    Current Research and Scholarly InterestsI am interested in magnetic resonance imaging (MRI) applications and augmented reality applications in medicine. These include abdominal, breast and musculoskeletal imaging, which require development of faster, quantitative, and more efficient MRI methods that provide improved diagnostic contrast compared with current methods. My work includes novel excitation schemes, efficient imaging methods and reconstruction tools and augmented reality in medicine.

  • Sarah Heilshorn

    Sarah Heilshorn

    Professor of Materials Science and Engineering and, by courtesy, of Bioengineering and of Chemical Engineering

    Current Research and Scholarly InterestsProtein engineering
    Tissue engineering
    Regenerative medicine
    Biomaterials

  • KC Huang

    KC Huang

    Professor of Bioengineering and of Microbiology and Immunology

    Current Research and Scholarly InterestsHow do cells determine their shape and grow?
    How do molecules inside cells get to the right place at the right time?

    Our group tries to answer these questions using a systems biology approach, in which we integrate interacting networks of protein and lipids with the physical forces determined by the spatial geometry of the cell. We use theoretical and computational techniques to make predictions that we can verify experimentally using synthetic, chemical, or genetic perturbations.

  • Possu Huang

    Possu Huang

    Assistant Professor of Bioengineering

    Current Research and Scholarly InterestsProtein design: molecular engineering, method development and novel therapeutics

  • Amit Kaushal

    Amit Kaushal

    Adjunct Professor

    BioAmit Kaushal, MD, PhD is Clinical Assistant Professor of Medicine (Stanford-VA) and Adjunct Professor of Bioengineering at Stanford University. Dr. Kaushal's work spans clinical medicine, teaching, research, and industry.

    He helped launch Stanford School of Engineering's undergraduate major in Biomedical Computation (bmc.stanford.edu) and has served as long-time director of the major. The major has graduated over 70 students since inception and was recently featured in Nature (https://go.nature.com/2P2UnRu).

    His research interests are in utilizing health data in novel and ethical ways to improve the practice of medicine. He is a faculty executive member of Stanford's Partnership for AI-Assisted Care (aicare.stanford.edu). Recently, he has also been working with public health agencies to improve scale and speed of contact tracing for COVID-19.

    He has previously held executive and advisory roles at startups working at the interface of technology and healthcare.

    He continues to practice as an academic hospitalist.

    Dr. Kaushal completed his BS (Biomedical Computation), MD, PhD (Biomedical Informatics), and residency training at Stanford. He is board-certified in Internal Medicine and Clinical Informatics.

  • Lukasz Kidzinski

    Lukasz Kidzinski

    Research Engineer

    BioŁukasz Kidziński is a research associate in the Neuromuscular Biomechanics Lab at Stanford, applying state-of-the-art computer vision and reinforcement learning algorithms for broadening our understanding of human movement and performance. Previously he was a researcher in the CHILI group, Computer-Human Interaction in Learning and Instruction, at the EPFL in Switzerland, where he was developing methods for measuring and improving engagement of users in massive online open courses. He obtained a Ph.D. degree at Université Libre de Bruxelles in mathematical statistics, working on frequency domain methods for time series of functional data.

  • Ellen Kuhl

    Ellen Kuhl

    Robert Bosch Chair of Mechanical Engineering, Professor of Mechanical Engineering and, by courtesy, of Bioengineering

    Current Research and Scholarly Interestscomputaitonal simulation of brain development, cortical folding, computational simulation of cardiac disease, heart failure, left ventricular remodeling, electrophysiology, excitation-contraction coupling, computer-guided surgical planning, patient-specific simulation

  • Jin Hyung Lee

    Jin Hyung Lee

    Associate Professor of Neurology, of Neurosurgery and of Bioengineering and, by courtesy, of Electrical Engineering

    Current Research and Scholarly InterestsIn vivo visualization and control of neural circuits

  • Craig Levin

    Craig Levin

    Professor of Radiology (Molecular Imaging Program at Stanford/Nuclear Medicine) and, by courtesy, of Physics, of Electrical Engineering and of Bioengineering

    Current Research and Scholarly InterestsMolecular Imaging Instrumentation
    Laboratory

    Our research interests involve the development of novel instrumentation and software algorithms for in vivo imaging of cellular and molecular signatures of disease in humans and small laboratory animal subjects.

  • Michael Lin

    Michael Lin

    Associate Professor of Neurobiology, of Bioengineering and, by courtesy, of Chemical and Systems Biology

    Current Research and Scholarly InterestsOur lab applies biochemical and engineering principles to the development of protein-based tools for investigating biology in living animals. Topics of investigation include fluorescent protein-based voltage indicators, synthetic light-controllable proteins, bioluminescent reporters, and applications to studying animal models of disease.

  • Alison Marsden

    Alison Marsden

    Associate Professor of Pediatrics (Cardiology) and of Bioengineering

    Current Research and Scholarly InterestsThe Cardiovascular Biomechanics Computation Lab at Stanford develops novel computational methods for the study of cardiovascular disease progression, surgical methods, and medical devices. We have a particular interest in pediatric cardiology, and use virtual surgery to design novel surgical concepts for children born with heart defects.

  • Lloyd B. Minor, MD

    Lloyd B. Minor, MD

    The Carl and Elizabeth Naumann Professorship for the Dean of the School of Medicine, Professor of Otolaryngology—Head & Neck Surgery and, by courtesy, of Neurobiology and Bioengineering

    BioLloyd B. Minor, MD, is a scientist, surgeon, and academic leader. He is the Carl and Elizabeth Naumann Dean of the Stanford University School of Medicine, a position he has held since December 2012.

    As dean, Dr. Minor plays an integral role in setting strategy for the clinical enterprise of Stanford Medicine, an academic medical center that includes the Stanford University School of Medicine, Stanford Health Care, and Stanford Children’s Health and Lucile Packard Children’s Hospital Stanford. He also oversees the quality of Stanford Medicine’s physician practices and growing clinical networks.

    With Dr. Minor’s leadership, Stanford Medicine has established a strategic vision to lead the biomedical revolution in Precision Health. The next generation of health care, Precision Health is focused on keeping people healthy and providing care that is tailored to individual variations. It’s predictive, proactive, preemptive, personalized, and patient-centered.

    An advocate for innovation, Dr. Minor has provided significant support for fundamental science and for clinical and translational research at Stanford. Through bold initiatives in medical education and increased support for PhD students, Dr. Minor is committed to inspiring and training future leaders.

    Among other accomplishments Dr. Minor has led the development and implementation of an innovative model for cancer research and patient care delivery at Stanford Medicine and has launched an initiative in biomedical data science to harness the power of big data and create a learning health care system. Committed to diversity, he has increased student financial aid and expanded faculty leadership opportunities.

    Before coming to Stanford, Dr. Minor was provost and senior vice president for academic affairs of The Johns Hopkins University. During his time as provost, Dr. Minor launched many university-wide initiatives such as the Gateway Sciences Initiative to support pedagogical innovation, and the Doctor of Philosophy Board to promote excellence in PhD education. He worked with others around the university and health system to coordinate the Individualized Health Initiative, which aimed to use genetic information to transform health care.

    Prior to his appointment as provost in 2009, Dr. Minor served as the Andelot Professor and director (chair) of the Department of Otolaryngology–Head and Neck Surgery in the Johns Hopkins University School of Medicine and otolaryngologist-in-chief of The Johns Hopkins Hospital. During his six-year tenure, he expanded annual research funding by more than half and increased clinical activity by more than 30 percent, while strengthening teaching efforts and student training.

    With more than 140 published articles and chapters, Dr. Minor is an expert in balance and inner ear disorders. Through neurophysiological investigations of eye movements and neuronal pathways, his work has identified adaptive mechanisms responsible for compensation to vestibular injury in a model system for studies of motor learning (the vestibulo-ocular reflex). The synergies between this basic research and clinical studies have led to improved methods for the diagnosis and treatment of balance disorders. In recognition of his work in refining a treatment for Ménière’s disease, Dr. Minor received the Prosper Ménière Society’s gold medal in 2010.

    In the medical community, Dr. Minor is perhaps best known for his discovery of superior canal dehiscence syndrome, a debilitating disorder characterized by sound- or pressure-induced dizziness. In 1998 Dr. Minor and colleagues published a description of the clinical manifestations of the syndrome and related its cause to an opening (dehiscence) in the bone covering the superior canal. He subsequently developed a surgical procedure that corrects the problem and alleviates symptoms.

    In 2012, Dr. Minor was elected to the National Academy of Medicine, formerly the Institute of Medicine.

  • Paul Nuyujukian

    Paul Nuyujukian

    Assistant Professor of Bioengineering and of Neurosurgery and, by courtesy, of Electrical Engineering

    Current Research and Scholarly InterestsOur group explores neuroengineering and its application to both basic and clinical neuroscience. Our goal is to develop brain-machine interfaces as a platform technology for a variety of brain-related medical conditions including stroke and epilepsy.

  • Kim Butts Pauly

    Kim Butts Pauly

    Professor of Radiology (Radiological Sciences Lab) and, by courtesy, of Electrical Engineering and of Bioengineering

    Current Research and Scholarly InterestsWe are investigating and developing, and applying focused ultrasound in neuromodulation, blood brain barrier opening, and ablation for both neuro and body applications.

  • Mr Ryan K Pierce

    Mr Ryan K Pierce

    Lecturer

    BioRyan Pierce is a Lecturer in Bioengineering, and Co-Founder and CEO of Nine, a neonatal/maternal health technology company. He has served as VP of Design and Innovation at Ventus Medical, VP of Business Development at Loma Vista Medical, a healthcare investor at De Novo Ventures, and a product designer at Concentric Medical and The Foundry/Zephyr Medical. He is currently an Entrepreneur-in-Residence at Rock Health, a digital health seed fund. An inventor on over two dozen U.S. patents, he holds mechanical engineering degrees from MIT and Stanford, and an MBA from Harvard Business School.

  • Manu Prakash

    Manu Prakash

    Associate Professor of Bioengineering and Senior Fellow at the Woods Institute for the Environment

    BioWe use interdisciplinary approaches including theory and experiments to understand how computation is embodied in biological matter. Examples include cognition in single cell protists and morphological computing in animals with no neurons and origins of complex behavior in multi-cellular systems. Broadly, we invent new tools for studying non-model organisms with significant focus on life in the ocean - addressing fundamental questions such as how do cells sense pressure or gravity? Finally, we are dedicated towards inventing and distributing “frugal science” tools to democratize access to science (previous inventions used worldwide: Foldscope, Abuzz), diagnostics of deadly diseases like malaria and convening global citizen science communities to tackle planetary scale environmental challenges such as mosquito surveillance or plankton surveillance by citizen sailors mapping the ocean in the age of Anthropocene.

  • Lei Stanley Qi

    Lei Stanley Qi

    Assistant Professor of Bioengineering and of Chemical and Systems Biology

    BioDr. Lei Stanley Qi is Assistant Professor in the Department of Bioengineering, Department of Chemical and Systems Biology, and a faculty fellow in Stanford ChEM-H. He is one of major contributors to the CRISPR technology development for genome engineering. He demonstrated the first use of the nuclease-deactivated Cas9 (dCas9) for genome targeting in cells. Using dCas9, His lab developed the CRISPR interference (CRISPRi) and CRISPR activation (CRISPRa) technologies for gene expression regulation, which is broadly used for high-throughput study of genomics in different organisms. He co-developed the CRISPR application for chromatin imaging in living cells. His lab greatly expanded the CRISPR toolbox for engineering the genome and epigenome, including multiplexed epigenome editing, programmable 3D genome manipulation (CRISPR-GO), live-cell imaging (LiveFISH), and CRISPR antivirals for targeting RNA viruses (PAC-MAN). He obtained B.S. in Physics from Tsinghua University, and Ph.D. in Bioengineering from the University of California Berkeley in 2012. He joined UCSF as Systems Biology Faculty Fellow between 2012 to 2014, and joined the faculty at Stanford University since 2014. His lab combines genome engineering with synthetic biology to understand the function of mammalian genomes and develop gene therapy.

  • Stephen Quake

    Stephen Quake

    Lee Otterson Professor in the School of Engineering and Professor of Bioengineering, of Applied Physics and, by courtesy, of Physics

    Current Research and Scholarly InterestsSingle molecule biophysics, precision force measurement, micro and nano fabrication with soft materials, integrated microfluidics and large scale biological automation.

  • Krishna Shenoy

    Krishna Shenoy

    Hong Seh and Vivian W. M. Lim Professor in the School of Engineering and Professor, by courtesy, of Neurobiology and of Bioengineering

    Current Research and Scholarly InterestsWe conduct neuroscience, neuroengineering and translational research to better understand how the brain controls movement, and to design medical systems to assist people with paralysis. These medical systems are referred to as brain-machine interfaces (BMIs), brain-computer interfaces (BCIs) and intra-cortical neural prostheses. We conduct this research as part of our Neural Prosthetic Systems Lab (NPSL) and our Neural Prosthetics Translational Lab (NPTL).

  • Christina Smolke

    Christina Smolke

    Adjunct Professor

    BioProfessor Smolke's research program focuses on developing modular genetic platforms for programming information processing and control functions in living systems, resulting in transformative technologies for engineering, manipulating, and probing biological systems. She has pioneered the design and application of a broad class of RNA molecules, called RNA devices, that process and transmit user-specified input signals to targeted protein outputs, thereby linking molecular computation to gene expression. This technology has been extended to efficiently construct multi-input devices exhibiting various higher-order information processing functions, demonstrating combinatorial assembly of many information processing, transduction, and control devices from a smaller number of components. Her laboratory is applying these technologies to addressing key challenges in cellular therapeutics, targeted molecular therapies, and green biosynthesis strategies.

  • Hyongsok Tom  Soh

    Hyongsok Tom Soh

    Professor of Radiology (Early Detection), of Electrical Engineering and, by courtesy, of Chemical Engineering and of Bioengineering

    BioDr. Soh received his B.S. with a double major in Mechanical Engineering and Materials Science with Distinction from Cornell University and his Ph.D. in Electrical Engineering from Stanford University. From 1999 to 2003, Dr. Soh served as the technical manager of MEMS Device Research Group at Bell Laboratories and Agere Systems. He was a faculty member at UCSB before joining Stanford in 2015. His current research interests are in analytical biotechnology, especially in high-throughput screening, directed evolution, and integrated biosensors.

  • James Swartz

    James Swartz

    James H. Clark Professor in the School of Engineering and Professor of Chemical Engineering and of Bioengineering

    BioUsing and Understanding Cell-Free Biology

    Swartz Lab General Research Focus:

    The current and projected research in the Swartz lab balances basic research in microbial metabolism, protein expression, and protein folding with a strong emphasis on compelling applications. The power and versatility of cell-free methods coupled with careful evaluation and engineering of these new systems enables a whole new range of applications and scientific investigation. Fundamental research on: the mechanisms and kinetics of ribosomal function, fundamental bioenergetics, basic mechanisms of protein folding, functional genomics, and metabolic pathway analysis is motivated by a variety of near- and medium term applications spanning medicine, energy, and environmental needs.

    Swartz Lab Application Focus:

    In the medical area , current research addresses the need for patient-specific vaccines to treat cancer. Particularly for lymphomas, there is a strong need to be able to make a new cancer vaccine for each patient. Current technologies are not practical for this demanding task, but cell-free approaches are rapid and inexpensive. We have already demonstrated feasibility in mouse tumor challenge studies and are now expanding the range of applications and working to improve the relevant technologies. Experience with these vaccines has also suggested a new and exciting format for making inexpensive and very potent vaccines for general use.

    To address pressing needs for a new and cleaner energy source, we are working towards an organism that can efficiently capture solar energy and convert it into hydrogen. The first task is to develop an oxygen tolerant hydrogenase using cell-free technology to express libraries of mutated enzymes that can be rapidly screened for improved function. Even though these are very complex enzymes, we have produced active hydrogenases with our cell-free methods. We are now perfecting the screening methods for rapid and accurate identification of improved enzymes. After these new enzymes are identified, the project will progress toward metabolic engineering and bioreactor design research to achieve the scales and economies required.

    To address environmental needs, we are developing an improved water filters using an amazing membrane protein, Aquaporin Z. It has the ability to reject all other chemicals and ions except water. We have efficiently expressed the protein into lipid bilayer vesicles and are now working to cast these membranes on porous supports to complete the development of a new and powerful water purification technology. The same lessons will be applied toward the development of a new class of biosensors that brings high sensitivity and selectivity.

  • Joseph D. Towles

    Joseph D. Towles

    Lecturer

    BioJoseph Towles is a Lecturer jointly appointed in the Mechanical Engineering and Bioengineering Departments at Stanford University. Joe’s teaching interests are in the areas of solid mechanics, neuromuscular biomechanics, dynamical systems and control, and engineering design. His scholarship interest is in the area of engineering education. Specifically, Joe's engineering education activities include student-centric course and curricular development; assessment of student learning & engagement; and innovation in approaches to enhance student learning.

    A Mechanical Engineer by training, Joe earned his BS degree in Mechanical Engineering from the University of Maryland Baltimore County and his MS and PhD degrees both in Mechanical Engineering from Stanford University (1996-2003). Following graduate school, Joe was a research post-doctoral fellow and subsequently a research scientist and then a research assistant professor in neuromuscular biomechanics in the Sensory Motor Performance Program at the Rehabilitation Institute of Chicago and in the Physical Medicine and Rehabilitation Department at Northwestern University (2003-2012). Additionally, Joe was a research health scientist for the Rehabilitation R&D Service in the Department of Veterans Affairs (Hines, IL) during that time and later a scientist in the neuromuscular biomechanics lab in the Mechanical Engineering Department at the University of Wisconsin-Madison (2012-2014). At the time, Joe led projects that addressed the broad question of how to restore hand function (ability to grasp objects) following cervical spinal cord injury and hemiparetic stroke using experimental and computational techniques in biomechanics. As a complement to teaching within the undergraduate and graduate curricula in Biomedical Engineering at the University of Wisconsin-Madison (2014-2018), and now teaching broadly within the undergraduate curricula of Mechanical Engineering and Bioengineering at Stanford, Joe's current scholarship interest has shifted to engineering education.

  • Ross Daniel Venook

    Ross Daniel Venook

    Lecturer, Bioengineering
    Senior Lecturer, Bioengineering

    BioRoss is a Lecturer in the Bioengineering department and he directs Engineering at the Stanford Byers Center for Biodesign.

    Ross co-leads two undergraduate courses at Stanford—an instrumentation lab (BIOE123) and an open-ended capstone design lab sequence (BIOE141A/B)—and he supports other courses and runs hands-on workshops in the areas of prototyping and systems engineering related to medical device innovation. He enjoys the unique challenges and constraints offered by biomedical engineering projects, and he delights in the opportunity for collaborative learning in a problem-solving environment.

    An Electrical Engineer by training (Stanford BS, MS, PhD), Ross’ graduate work focused on building and applying new types of MRI hardware for interventional and device-related uses. Following a Biodesign Innovation fellowship, Ross helped to start the MRI safety program at Boston Scientific Neuromodulation, where he continues working across the MRI safety community to create and improve international standards and to enable safe MRI access for patients with implanted medical devices.

  • Bo Wang

    Bo Wang

    Assistant Professor of Bioengineering

    BioWe are a discovery-driven research group working at the interface between developmental biology, bioengineering, and statistical physics. We combine quantitative organism-wide fluorescence imaging ("deep imaging"), functional genomics ("deep sequencing"), and physical modeling to understand the fundamental rules that control collective cell behaviors to optimize tissue regeneration, adaptation, and evolution. We also seek for opportunities for applying these rules to improve multicellular engineering systems.

  • Paul  J. Wang, MD

    Paul J. Wang, MD

    Professor of Medicine (Cardiovascular Medicine) at the Stanford University Medical Center and, by courtesy, of Bioengineering

    Current Research and Scholarly InterestsDr. Wang's research centers on the development of innovative approaches to the treatment of arrhythmias, including more effective catheter ablation techniques, more reliable implantable devices, and less invasive treatments. Dr. Wang's clinical research interests include atrial fibrillation, ventricular tachycardia, syncope, and hypertrophic cardiomyopathy. Dr. Wang has active collaborations with Bioengineering, Mechanical Engineering, and Electrical Engineering Departments at Stanford.

  • Fan Yang

    Fan Yang

    Associate Professor of Orthopaedic Surgery and of Bioengineering

    Current Research and Scholarly InterestsOur research seeks to understand how microenvironmental cues regulate stem cell fate, and to develop novel biomaterials and stem cell-based therapeutics for tissue engineering and regenerative medicine. Our work spans from fundamental science, technology development, to translational research.We are particularly interested in developing better therapies for treating musculoskeletal diseases, cardiovascular diseases and cancer.

  • Paul Yock, MD

    Paul Yock, MD

    The Martha Meier Weiland Professor in the School of Medicine, Professor of Bioengineering and, by courtesy, of Mechanical Engineering

    Current Research and Scholarly InterestsHealth technology innovation using the Biodesign process: a systematic approach to the design of biomedical technologies based on detailed clinical and economic needs characterization. New approaches for interdisciplinary training of health technology innovators, including processes for identifying value opportunities in creating new technology-based approaches to health care.