School of Engineering
Showing 51-100 of 101 Results
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Jin Hyung Lee
Associate Professor of Neurology (Neurology Research Faculty), of Neurosurgery and of Bioengineering and, by courtesy, of Electrical Engineering
Current Research and Scholarly InterestsIn vivo visualization and control of neural circuits
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Craig Levin
Professor of Radiology (Molecular Imaging Program at Stanford/Nuclear Medicine) and, by courtesy, of Physics, of Electrical Engineering and of Bioengineering
Current Research and Scholarly InterestsMolecular Imaging Instrumentation
Laboratory
Our research interests involve the development of novel instrumentation and software algorithms for in vivo imaging of cellular and molecular signatures of disease in humans and small laboratory animal subjects. -
Michael Lin
Associate Professor of Neurobiology, of Bioengineering and, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly InterestsOur lab applies biochemical and engineering principles to the development of protein-based tools for investigating biology in living animals. Topics of investigation include fluorescent protein-based voltage indicators, synthetic light-controllable proteins, bioluminescent reporters, and applications to studying animal models of disease.
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Joshua Makower
Yock Family Professor and Professor of Bioengineering
Current Research and Scholarly InterestsDr. Josh Makower is the Boston Scientific Applied Bioengineering Professor of Medicine and of Bioengineering at the Stanford University Schools of Medicine and Engineering and the Director of the Stanford Byers Center for Biodesign, the program he co-founded with Dr. Paul Yock twenty years ago. Josh helped create the fundamental structure of the Center’s core curriculum and is the chief architect of what is now called “The Biodesign Process.” Over the past 20 years since Josh and Paul founded Biodesign, this curriculum and the associated textbook has been used at Stanford and across the world to train hundreds of thousands of students, faculty and industry leaders on the Biodesign process towards the advancement of medical innovation for the improvement of patient care. Josh has practiced these same techniques directly as the Founder & Executive Chairman of ExploraMed, a medical device incubator, creating 9 companies since 1995. Transactions from the ExploraMed portfolio include NeoTract, acquired by Teleflex, Acclarent, acquired by J&J, EndoMatrix, acquired by C.R. Bard & TransVascular, acquired by Medtronic. Other ExploraMed/NEA ventures include Moximed, NC8 and Willow. Josh is also a Special Partner at NEA where he supports the healthcare team and medtech/healthtech investing practice. Josh serves on the boards of Allay Therapeutics, Revelle Aesthetics, Setpoint Medical, DOTS Technologies, Eargo, ExploraMed, Intrinsic Therapeutics, Moximed, Willow and Coravin. Josh holds over 300 patents and patent applications. He received an MBA from Columbia University, an MD from the NYU School of Medicine, a bachelor’s degree in Mechanical Engineering from MIT. Josh is a Member of the National Academy of Engineering and the College of Fellows of The American Institute for Medical and Biological Engineering and was awarded the Coulter Award for Healthcare Innovation by the Biomedical Engineering Society in 2018.
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Alison Marsden
Douglass M. and Nola Leishman Professor of Cardiovascular Diseases, Professor of Pediatrics (Cardiology) and of Bioengineering and, by courtesy, of Mechanical Engineering
Current Research and Scholarly InterestsThe Cardiovascular Biomechanics Computation Lab at Stanford develops novel computational methods for the study of cardiovascular disease progression, surgical methods, and medical devices. We have a particular interest in pediatric cardiology, and use virtual surgery to design novel surgical concepts for children born with heart defects.
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Michaëlle Ntala Mayalu
Assistant Professor of Mechanical Engineering and, by courtesy, of Bioengineering
BioDr. Michaëlle N. Mayalu is an Assistant Professor of Mechanical Engineering. She received her Ph.D., M.S., and B.S., degrees in Mechanical Engineering at the Massachusetts Institute of Technology. She was a postdoctoral scholar at the California Institute of Technology in the Computing and Mathematical Sciences Department. She was a 2017 California Alliance Postdoctoral Fellowship Program recipient and a 2019 Burroughs Wellcome Fund Postdoctoral Enrichment Program award recipient. She is also a 2023 Hypothesis Fund Grantee.
Dr. Michaëlle N. Mayalu's area of expertise is in mathematical modeling and control theory of synthetic biological and biomedical systems. She is interested in the development of control theoretic tools for understanding, controlling, and predicting biological function at the molecular, cellular, and organismal levels to optimize therapeutic intervention.
She is the director of the Mayalu Lab whose research objective is to investigate how to optimize biomedical therapeutic designs using theoretical and computational approaches coupled with experiments. Initial project concepts include: i) theoretical and experimental design of bacterial "microrobots" for preemptive and targeted therapeutic intervention, ii) system-level multi-scale modeling of gut associated skin disorders for virtual evaluation and optimization of therapy, iii) theoretical and experimental design of "microrobotic" swarms of engineered bacteria with sophisticated centralized and decentralized control schemes to explore possible mechanisms of pattern formation. The experimental projects in the Mayalu Lab utilize established techniques borrowed from the field of synthetic biology to develop synthetic genetic circuits in E. coli to make bacterial "microrobots". Ultimately the Mayalu Lab aims to develop accurate and efficient modeling frameworks that incorporate computation, dynamical systems, and control theory that will become more widespread and impactful in the design of electro-mechanical and biological therapeutic machines. -
Lloyd B. Minor, MD
The Carl and Elizabeth Naumann Dean of the School of Medicine, Vice President for Medical Affairs, Stanford University, Professor of Otolaryngology - Head and Neck Surgery and Professor of Neurobiology and of Bioengineering, by courtesy
Current Research and Scholarly InterestsThrough neurophysiological investigations of eye movements and neuronal pathways, Dr. Minor has identified adaptive mechanisms responsible for compensation to vestibular injury in a model system for studies of motor learning. Following his discovery of superior canal dehiscence, he published a description of the disorder’s clinical manifestations and related its cause to an opening in the bone covering of the superior canal. He subsequently developed a surgical procedure to correct the problem.
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Paul Nuyujukian
Assistant Professor of Bioengineering and of Neurosurgery and, by courtesy, of Electrical Engineering
Current Research and Scholarly InterestsOur group explores neuroengineering and its application to both basic and clinical neuroscience. Our goal is to develop brain-machine interfaces as a platform technology for a variety of brain-related medical conditions including stroke and epilepsy.
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Daniel J O'Shea
Research Engineer
Current Research and Scholarly InterestsI study the neural mechanisms that control movement, and more broadly, how neural populations spanning interconnected brain regions perform the distributed computations that drive skilled behavior. I develop experimental and computational tools to understand the neural population dynamics that establish speed and dexterity.
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Kim Butts Pauly
Professor of Radiology (Radiological Sciences Lab) and, by courtesy, of Electrical Engineering and of Bioengineering
Current Research and Scholarly InterestsWe are investigating and developing, and applying focused ultrasound in neuromodulation, blood brain barrier opening, and ablation for both neuro and body applications.
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Matthew Petrucci
Research Engineer
BioMatt is the Scientific Program Manager for the Mobilize and Restore Centers at Stanford University. He is interested in developing digital health tools that optimize human mobility and performance. His previous research has focused on cross-sectional, longitudinal, translational, and feasibility studies in people with Parkinson’s disease, people with multiple sclerosis, and firefighters. These studies included evaluating objective biomarkers of disease or performance, optimizing and evaluating novel treatments and interventions, developing real-time closed-loop algorithms, and clinical trials. He helps run the various scientific outreach and training programs of the Mobilize and Restore Centers.
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Grigore Pintilie
Research Scientist
BioYork University, B.Sc. 1995-1999, Computer Science - Computer Graphics, HCI
University of Toronto, M.Sc. 1999-2001, Computer Science, Computer Graphics
Blueprint Initiative, 2001-2005 - Bioinformatics Research
MIT, Ph.D. 2005-2011 - Electrical Engineering and Computer Science, Biology - CryoEM map segmentation and fitting of atomic models
Baylor College of Medicine 2011-2017 - Scientific Programmer - Cryo-EM map analysis and atomic modeling
Stanford University 2017-present - Research Scientist - Cryo-EM map analysis and atomic modeling -
Gordon Pipa
Visiting Professor, Bioengineering
BioGordon Pipa is a visiting Professor at Stanford. His research is focused on understanding the principles of neuronal coding and learning in spiking recurrent neuronal networks with the goal to enable building future neuromorphic AI systems. A main focus is on understanding the dendritic information processing in the context of the large spiking neuronal networks. In the past, he held position at the Max-Planck for Brain Research (Wolf Singer), MIT (Emery Brown), TU Berlin (Klaus Obermayer).
He currently holds the following positions: Visiting Professor at Stanford, Bioengineering, Chair of the Neuroinformatics Dep., Institute of Cognitive Science at the Osnabrück University (Germany), Director of the Institute of Cognitive Science at the Osnabrück University (Germany), Fellow at the Frankfurt Institute of Advanced Studies (Germany) -
Manu Prakash
Associate Professor of Bioengineering, Senior Fellow at the Woods Institute for the Environment and Associate Professor, by courtesy, of Oceans and of Biology
BioWe use interdisciplinary approaches including theory and experiments to understand how computation is embodied in biological matter. Examples include cognition in single cell protists and morphological computing in animals with no neurons and origins of complex behavior in multi-cellular systems. Broadly, we invent new tools for studying non-model organisms with significant focus on life in the ocean - addressing fundamental questions such as how do cells sense pressure or gravity? Finally, we are dedicated towards inventing and distributing “frugal science” tools to democratize access to science (previous inventions used worldwide: Foldscope, Abuzz), diagnostics of deadly diseases like malaria and convening global citizen science communities to tackle planetary scale environmental challenges such as mosquito surveillance or plankton surveillance by citizen sailors mapping the ocean in the age of Anthropocene.
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Patrick Lee Purdon
Professor of Anesthesiology, Perioperative and Pain Medicine and, by courtesy, of Bioengineering
BioMy research integrates neuroimaging, biomedical signal processing, and the systems neuroscience of general anesthesia and sedation.
My group conducts human studies of anesthesia-induced unconsciousness, using a variety of techniques including multimodal neuroimaging, high-density EEG, and invasive neurophysiological recordings used to diagnose medically refractory epilepsy. We also develop novel methods in neuroimaging and biomedical signal processing to support these studies, as well as methods for monitoring level of consciousness under general anesthesia using EEG. -
Lei (Stanley) Qi
Associate Professor of Bioengineering
BioDr. Lei (Stanley) Qi is Associate Professor of Bioengineering, Sarafan ChEM-H, and a Chan Zuckerberg Biohub Investigator. Dr. Qi is a principal contributor to the development of CRISPR technologies for genome engineering beyond gene editing. His lab created the first nuclease-deactivated Cas9 (dCas9) for targeted gene regulation in cells. His lab has invented a CRISPR toolbox for engineering the epigenome, including CRISPRi and CRISPRa for targeted gene repression and activation, epigenome editing, LiveFISH for real-time DNA/RNA imaging, CRISPR-GO for 3D genome manipulation, CasMINI as a compact CRISPR system for gene therapy, hyperCas12a for multi-gene engineering, and CRISPR antivirals aimed at treating broad RNA viruses.
Dr. Qi obtained B.S. in Physics and Math from Tsinghua University in 2005, and Ph.D. in Bioengineering from the University of California, Berkeley in 2012. He was a Systems Biology Faculty Fellow at UCSF between 2012-2014, and joined Stanford faculty in 2014. His research focuses on mammalian synthetic biology, epigenetic engineering, immune cell engineering, directed evolution, and novel approaches for gene therapy. -
Stephen Quake
Lee Otterson Professor in the School of Engineering and Professor of Bioengineering, of Applied Physics and, by courtesy, of Physics
Current Research and Scholarly InterestsSingle molecule biophysics, precision force measurement, micro and nano fabrication with soft materials, integrated microfluidics and large scale biological automation.
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Peter L. Santa Maria, MBBS, PhD
Associate Professor of Otolaryngology - Head & Neck Surgery (OHNS) and, by courtesy, of Bioengineering
On Partial Leave from 08/01/2023 To 07/14/2024Current Research and Scholarly InterestsWe study chronic suppurative otitis media, a chronic biofilm infection of the middle ear predominantly involving pseudomonas and staph aureus. We are investigating mechanisms of sensory hearing loss, host microbe interactions and trialling novel therapeutics.
Our work in tympanic membrane regeneration has entered clinical trials.
Novel treatments for wound healing in intra oral wounds with potential applications to prevent post tonsillectomy wound healing and oral mucositis. -
Luise Avelina Seeker
Basic Life Research Scientist
BioLuise Seeker is a trained vet from Berlin, Germany with a strong interest in researching ageing at a cellular level. She obtained a PhD in Genomics from the University of Edinburgh in 2018 for studying telomeres, their heritability and their power to predict lifespan (supervised by Profs. Georgios Banos, Dan Nussey, Mike Coffey and Bruce Whitelaw). She joined Prof. Anna Williams' lab at the University of Edinburgh as a postdoc and investigated transcriptional changes with ageing in the human central nervous system.
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Hyongsok Tom Soh
Professor of Radiology (Early Detection), of Electrical Engineering, of Bioengineering and, by courtesy, of Chemical Engineering
BioDr. Soh received his B.S. with a double major in Mechanical Engineering and Materials Science with Distinction from Cornell University and his Ph.D. in Electrical Engineering from Stanford University. From 1999 to 2003, Dr. Soh served as the technical manager of MEMS Device Research Group at Bell Laboratories and Agere Systems. He was a faculty member at UCSB before joining Stanford in 2015. His current research interests are in analytical biotechnology, especially in high-throughput screening, directed evolution, and integrated biosensors.
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James Swartz
James H. Clark Professor in the School of Engineering and Professor of Chemical Engineering and of Bioengineering
Current Research and Scholarly InterestsProgram Overview
The world we enjoy, including the oxygen we breathe, has been beneficially created by biological systems. Consequently, we believe that innovative biotechnologies can also serve to help correct a natural world that non-natural technologies have pushed out of balance. We must work together to provide a sustainable world system capable of equitably improving the lives of over 10 billion people.
Toward that objective, our program focuses on human health as well as planet health. To address particularly difficult challenges, we seek to synergistically combine: 1) the design and evolution of complex protein-based nanoparticles and enzymatic systems with 2) innovative, uniquely capable cell-free production technologies.
To advance human health we focus on: a) achieving the 120 year-old dream of producing “magic bullets”; smart nanoparticles that deliver therapeutics or genetic therapies only to specific cells in our bodies; b) precisely designing and efficiently producing vaccines that mimic viruses to stimulate safe and protective immune responses; and c) providing a rapid point-of-care liquid biopsy that will count and harvest circulating tumor cells.
To address planet health we are pursuing biotechnologies to: a) inexpensively use atmospheric CO2 to produce commodity biochemicals as the basis for a new carbon negative chemical industry, and b) mitigate the intermittency challenges of photovoltaic and wind produced electricity by producing hydrogen either from biomass sugars or directly from sunlight.
More than 25 years ago, Professor Swartz began his pioneering work to develop cell-free biotechnologies. The new ability to precisely focus biological systems toward efficiently addressing new, “non-natural” objectives has proven tremendously useful as we seek to address the crucial and very difficult challenges listed above. Another critical feature of the program is the courage (or naivete) to approach important objectives that require the development and integration of several necessary-but- not-sufficient technology advances. -
Sindy Tang
Associate Professor of Mechanical Engineering, Senior Fellow at the Woods Institute for the Environment and Professor, by courtesy, of Radiology and of Bioengineering
On Leave from 04/01/2024 To 06/30/2024Current Research and Scholarly InterestsThe long-term goal of Dr. Tang's research program is to harness mass transport in microfluidic systems to accelerate precision medicine and material design for a future with better health and environmental sustainability.
Current research areas include: (I) Physics of droplets in microfluidic systems, (II) Interfacial mass transport and self-assembly, and (III) Applications in food allergy, single-cell wound repair, and the bottom-up construction of synthetic cell and tissues in close collaboration with clinicians and biochemists at the Stanford School of Medicine, UCSF, and University of Michigan.
For details see https://web.stanford.edu/group/tanglab/ -
Hawa Racine Thiam
Assistant Professor of Bioengineering and of Microbiology and Immunology
Current Research and Scholarly InterestsCellular Biophysical Mechanisms of Innate Immune Cells Functions
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Scott Uhlrich
Research Engineer
Current Research and Scholarly InterestsExperimental biomechanical analysis of healthy and pathological human movement. Real-time biofeedback to modify motor control and kinematics.
Musculoskeletal modeling and simulation for estimating unmeasurable quantities during movement, like joint forces in individuals with osteoarthritis. Predictive musculoskeletal simulations to design rehabilitation interventions.
Computer vision, wearable sensing, and machine learning to develop tools that democratize biomechanical analysis and translate biomechanical interventions into clinical practice.
Quantitative MRI for analyzing the effect of non-surgical treatments for osteoarthritis on cartilage health. PET-MRI for analyzing relationships between the mechanical loading of tissue metabolic activity. -
Ross Daniel Venook
Senior Lecturer of Bioengineering
BioRoss is a Senior Lecturer in the Bioengineering department and he is the Associate Director for Engineering at the Stanford Byers Center for Biodesign.
Ross primarily co-leads undergraduate laboratory courses at Stanford—an instrumentation lab (BIOE123) and an open-ended capstone design lab sequence (BIOE141A/B)—and he supports other courses and runs hands-on workshops in the areas of prototyping and systems engineering related to medical device innovation. He enjoys the unique challenges and constraints offered by biomedical engineering projects, and he delights in the opportunity for collaborative learning in a problem-solving environment.
An Electrical Engineer by training (Stanford BS, MS, PhD), Ross’ graduate work focused on building and applying new types of MRI hardware for interventional and device-related uses. Following a Biodesign Innovation fellowship, Ross helped to start the MRI safety program at Boston Scientific Neuromodulation, where he worked for 15 years to enable safe MRI access for patients with implanted medical devices--including collaboration across the MRI safety community to create and improve international standards. -
James Wall
Associate Professor of Surgery (Pediatric Surgery) and, by courtesy, of Bioengineering
On Partial Leave from 07/01/2023 To 06/30/2024Current Research and Scholarly InterestsHealth Technology Innovation
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Bo Wang
Assistant Professor of Bioengineering and, by courtesy, Developmental Biology
Current Research and Scholarly InterestsResearch interests:
(1) Systems biology of whole-body regeneration
(2) Cell type evolution through the lens of single-cell multiomic sequencing analysis
(3) Quantitative biology of brain regeneration
(4) Regeneration of animal-algal photosymbiotic systems -
Paul J. Wang, MD
John R. and Ai Giak L. Singleton Director, Professor of Medicine (Cardiovascular Medicine) and, by courtesy, of Bioengineering
Current Research and Scholarly InterestsDr. Wang's research centers on the development of innovative approaches to the treatment of arrhythmias, including more effective catheter ablation techniques, more reliable implantable devices, and less invasive treatments. Dr. Wang's clinical research interests include atrial fibrillation, ventricular tachycardia, syncope, and hypertrophic cardiomyopathy. Dr. Wang is committed to addressing disparities in care and is actively involved in increasing diversity in clinical trials.
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Rahel Woldeyes
Basic Life Research Scientist
BioThe goal of my current research is to use high-resolution imaging techniques to interrogate outstanding questions in cardiac cell biology, with a focus on the signaling pathways that trigger heart muscle contraction. I currently use cryo-electron tomography-based imaging approaches to connect the molecular and cellular scales of biology and accelerate our understanding of human health and disease.
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Joseph Woo, MD, FACS, FACC, FAHA
Norman E. Shumway Professor, Professor of Cardiothoracic Surgery and, by courtesy, of Bioengineering
BioDr. Woo is a nationally recognized surgeon, innovator, researcher, and educator in cardiothoracic surgery.
He chairs the Stanford Health Cardiothoracic Surgery Department. He is the Norman E. Shumway Professor of Cardiothoracic Surgery and holds a courtesy appointment in the Department of Bioengineering.
Dr. Woo is a board-certified, fellowship-trained heart surgeon with an active clinical practice of more than 300 pump cases per year. He focuses on complex mitral and aortic valve repair, thoracic aortic surgery, cardiopulmonary transplantation, and minimally invasive surgery.
He has advanced these fields by developing innovative surgical procedures. He serves as principal investigator on two studies funded by National Institutes of Health (NIH) grants. One explores stem cells, angiogenesis, tissue engineering, and valvular biomechanics. Dr. Woo has received NIH funding for this study continuously since 2004.
He has served as primary investigator for clinical device trials. He also has been the primary investigator for translational scientific clinical trials entailing administration of stem cells during coronary artery bypass grafting and left ventricular arterial device (LVAD) implantation.
Dr. Woo has co-authored more than 400 articles in peer-reviewed publications.
Dr. Woo serves on the board of directors of the American Association for Thoracic Surgery (AATS). He is the president of the AATS Cardiac Surgery Biology Club. He is a fellow of the American College of Surgeons, American College of Cardiology, and American Heart Association. He serves on the leadership committee of the American Heart Association’s Council on Cardiovascular Surgery and Anesthesia.
He is a member of the Society of Thoracic Surgeons, International Society for Minimally Invasive Cardiac Surgery, International Society for Heart & Lung Transplantation, International Society for Heart Research, and other professional societies. -
Fan Yang
Associate Professor of Orthopaedic Surgery and of Bioengineering
Current Research and Scholarly InterestsOur lab’s mission is to develop therapies for regenerating human tissues lost due to diseases or aging, and to build tissue engineered 3D models for understanding disease progression and informing drug discovery. We invent biomaterials and engineering tools to elucidate and modulate biology, and also use biology to inform materials and engineering design. Our work is highly interdisciplinary, and is driven by unmet clinical needs or key gaps in biology.
