School of Engineering
Showing 51-81 of 81 Results
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Anja Redecker, MD
Postdoctoral Scholar, Chemical Engineering
BioAnja Redecker attended medical school in Germany (RWTH Aachen). For her doctoral thesis - under the guidance of Univ.-Prof. Dr. rer. nat. Lüscher – she studied the functions of a protein called ASH2L, which plays a role in tumorigenesis. She analyzed the effects of ASH2L domain deletion mutants on cell growth and histone trimethylation as well as targeted ASH2L fused to dCas9 to specific promoters and examined its effects on transcription activation.
Her current research in the Swartz Lab at Stanford University focusses on engineering Hepatitis B core virus-like particles (HBc VLP) for targeted delivery of chemotherapeutics and for vaccines. The envisioned targeting delivery system allows loading the HBc VLPs with chemotherapeutics and attaching targeting ligands like single chain antibody fragments to the HBc VLP surface. This would increase targeted accumulation of the chemotherapeutic at the tumor site and decrease therapy-limiting side effects by minimizing off-target effects. To combat any new pandemic efficiently, vaccines need to be engineered and produced quickly. This fast response can be made possible by using pre-produced HBc VLPs to which the antigen of the new circulating pathogen can be attached. This technology has the potential to curb the outbreak of a new pandemic. -
Laura Rijns
Postdoctoral Scholar, Chemical Engineering
BioDr. Laura Rijns was born in the Netherlands (Nov 10, 1996) and is currently a postdoc at Stanford University with prof. Zhenan Bao in close collaboration with prof. Karl Deisseroth, focussed on improving the communication between electronic materials and living tissue. Control on the cellular side (through genetic modification) is combined with control on the material side (through molecular engineering) to manipulate neural circuit activity both in-vitro in living neurons and in-vivo in living animals.
Laura obtained her PhD (2023) in Biomedical Engineering “cum laude” from Eindhoven University of Technology (TU/e) with prof. Patricia Dankers and prof. E.W. (Bert) Meijer. Supramolecular hydrogels as mimics of the extracellular matrix were developed for cell and organoid culture.
Prior to graduate school, Laura received her BSc (2017) and MSc (2019) in Biomedical Engineering at TU/e in the lab of prof. E.W. (Bert) Meijer, focused on supramolecular assemblies. During her undergraduate studies, she was the Lab Captain of the iGEM TU/e 2016 team, studying regulatable scaffold proteins. In 2017, she worked at UC Santa Barbara in the group of prof. Songi Han, studying liquid-liquid phase separated coacervate polymers. In 2019 and 2023, she worked at EPFL (Switzerland) with prof. Maartje Bastings, studying multivalent interactions using DNA origami. -
Johanna Schroeder
Postdoctoral Scholar, Chemical Engineering
BioSince July 2023: Postdoc.Mobility Fellow of Swiss National Science Foundation (SNSF)
April 2022 - June 2023: Postdic Fellow of German National Academy of Sciences Leopoldina -
Carlos Vera
Postdoctoral Scholar, Cardiovascular Institute
Postdoctoral Scholar, Chemical EngineeringBioCarlos obtained his B.S. in Industrial Biotechnology from the University of Puerto Rico at Mayaguez. He received his PhD from the University of Colorado at Boulder working with Dr. Leslie Leinwand on myosin myopathies. His dissertation focused on analyzing the effects on myosin's cross-bridge cycle from mutations associated to Hypertrophic (HCM) and Dilated (DCM) cardiomyopathies. For his postdoc he will focus on disease mechanisms that can influence severity.
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Kindle Williams
Postdoctoral Scholar, Chemical Engineering
Current Research and Scholarly InterestsKindle is a postdoctoral researcher in Prof. William Tarpeh's group. She studies nutrient recovery from wastewaters, with a particular focus on electrochemical techniques for the conversion and recovery of inorganic nitrogen species. She is interested in translating technologies for nutrient recovery to practice.
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熊剑 (Jian Xiong)
Postdoctoral Scholar, Chemical Engineering
BioI thrive to understand the roles of lysosomes in physiological and pathological conditions. Lysosomes are both degradation compartment and metabolic controlling hub, and dysregulation of lysosomal functions are frequently implicated in a vast number of diseases including neurodegenerative diseases, however, the systematic knowledge of the molecular mechanism by which lysosomal contributes to these diseases is lacking. Ion channels are the primary mediators of neuronal activity, defects in neuronal ion channel activity are linked with many kinds of neurodegenerative diseases. Interestingly, besides typical ion channels that are involved in the neuronal activity, defects in lysosomal ion channels, such as TRPML1, CLN7 and CLC-7 are also implicated in neuropathy. My previous work as Ph.D student in University of Texas MD Anderson Cancer Center focused on regulation of lysosomal function by ion channels and metabolites. I discovered a mechanism of lysosomal Na+ channel regulate mTORC1 activation by regulating lysosomal amino acid accumulation. I also discovered role of glutamine in controlling lysosomal degradation capacity. In the meantime, I developed novel methods to isolate organelles. My ultimate research goal is to understand the key developmental pathways and how alterations in gene sequences and expression contribute to human disease, therefore, I am pursuing independent academic researcher as my career goal. Starting Feb 2022, I work with Dr. Monther Abu-Remaileh at Stanford University on role of lysosomes in neurodegenerative diseases. I use genetics, chemical biology and omics approaches to study lysosome function under various physiological and pathological conditions, especially age-associated neurodegenerative disorders, and monogenic neurodegenerative lysosome storage diseases. In Stanford, I aim to integrate ionic regulation, metabolomic regulation and functional proteomic regulation to systematically understand the biology of lysosome in physiological conditions and pathological conditions.
