School of Humanities and Sciences
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Professor of Physics, Emeritus
Current Research and Scholarly InterestsProbes (accretion disks, ...) of black holes, sources and detectors of gravitational radiation, theories of gravitation, anthropic cosmological principle.
Professor of Biology
Current Research and Scholarly InterestsOur current focus is on maize anther development to understand how cell fate is specified. We discovered that hypoxia triggers specification of the archesporial (pre-meiotic) cells, and that these cells secrete a small protein MAC1 that patterns the adjacent soma to differentiate as endothecial and secondary parietal cell types. We also discovered a novel class of small RNA: 21-nt and 24-nt phasiRNAs that are exceptionally abundant in anthers and exhibit strict spatiotemporal dynamics.
Professor of Statistics
BioGuenther Walther studied mathematics, economics, and computer science at the University of Karlsruhe in Germany and received his Ph.D. in Statistics from UC Berkeley in 1994.
His research has focused on statistical methodology for detection problems, shape-restricted inference, and mixture analysis, and on statistical problems in astrophysics and in flow cytometry.
He received a Terman fellowship, a NSF CAREER award, and the Distinguished Teaching Award of the Dean of Humanities and Sciences at Stanford. He has served on the editorial boards of the Journal of Computational and Graphical Statistics, the Journal of the Royal Statistical Society, the Annals of Statistics, the Annals of Applied Statistics, and Statistical Science. He was program co-chair of the 2006 Annual Meeting of the Institute of Mathematical Statistics and served on the executive committee of IMS from 1998 to 2012.
Dr. Zhiyong Wang
Professor (By Courtesy), Biology
BioDr. Wang is the acting director of the Department of Plant Biology, Carnegie Institution for Science, and a professor by courtesy of the Department of Biology, Stanford University. He is currently an associate editor of Molecular Cellular Proteomics, and editorial board member of Molecular Plant. He is a Fellow of the American Association for the Advancement of Science (AAAS) and recipient of the Humboldt Research Prize.
Dr. Wang obtained his Ph.D. in 1998 from UCLA, where he cloned the plant circadian clock gene CCA1. He did his postdoctoral research at the Salk Institute, where he studied the brassinosteroid signaling mechanism mediated by the BRI1 receptor kinase. Since joining Carnegie in 2001, his research has illustrated the receptor kinase signaling pathway that links the BRI1 receptor kinase to the BZR1 transcription factor and brassinosteroid-responsive genes in the Arabidopsis genome. He further demonstrated how the steroid signaling pathway integrates at the molecular level with other hormonal pathways, light signaling pathways, nutrient-sensing pathways, immunity pathways, and the circadian clock, to coordinately regulate plant growth and development. His lab uses combinations of genomic and proteomic approaches to understand how cellular signals are transduced and integrated through posttranslational modifications (e.g. phosphorylation and O-Glycosylation) and protein-protein interactions. His studies are elucidating the molecular mechanisms that control plant growth and mediate responses to environmental changes.
Professor of Biology, Emeritus
Current Research and Scholarly InterestsEvolutionary adaptive mechanisms, molecules to ecosystems
Robert Eckles Swain Professor of Chemistry and Professor, by courtesy, of Chemical EngineeringOn Leave from 01/01/2022 To 12/31/2022
BioRobert Eckles Swain Professor in Chemistry Robert Waymouth investigates new catalytic strategies to create useful new molecules, including bioactive polymers, synthetic fuels, and sustainable plastics. In one such breakthrough, Professor Waymouth and Professor Wender developed a new class of gene delivery agents.
Born in 1960 in Warner Robins, Georgia, Robert Waymouth studied chemistry and mathematics at Washington and Lee University in Lexington, Virginia (B.S. and B.A., respectively, both summa cum laude, 1982). He developed an interest in synthetic and mechanistic organometallic chemistry during his doctoral studies in chemistry at the California Institute of Technology under Professor R.H. Grubbs (Ph.D., 1987). His postdoctoral research with Professor Piero Pino at the Institut fur Polymere, ETH Zurich, Switzerland, focused on catalytic hydrogenation with chiral metallocene catalysts. He joined the Stanford University faculty as assistant professor in 1988, becoming full professor in 1997 and in 2000 the Robert Eckles Swain Professor of Chemistry.
Today, the Waymouth Group applies mechanistic principles to develop new concepts in catalysis, with particular focus on the development of organometallic and organic catalysts for the synthesis of complex macromolecular architectures. In organometallic catalysis, the group devised a highly selective alcohol oxidation catalyst that selectively oxidizes unprotected polyols and carbohydrates to alpha-hyroxyketones. In collaboration with Dr. James Hedrick of IBM, we have developed a platform of highly active organic catalysts and continuous flow reactors that provide access to polymer architectures that are difficult to access by conventional approaches.
The Waymouth group has devised selective organocatalytic strategies for the synthesis of functional degradable polymers and oligomers that function as "molecular transporters" to deliver genes, drugs and probes into cells and live animals. These advances led to the joint discovery with the Wender group of a general, safe, and remarkably effective concept for RNA delivery based on a new class of synthetic cationic materials, Charge-Altering Releasable Transporters (CARTs). This technology has been shown to be effective for mRNA based cancer vaccines.
Francis W. Bergstrom Professor and Professor, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly InterestsMolecular imaging, therapeutics, drug delivery, drug mode of action, synthesis
Professor of Biological Sciences and Dean of the School of Humanities and Sciences, Emeritus
Current Research and Scholarly InterestsAnnual survey of rainbow and brown trout in northern lakes on the North Island of New Zealand. !995-2018, et seq.