School of Medicine
Showing 1-4 of 4 Results
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Stephen J. Galli, MD
Mary Hewitt Loveless, MD, Professor in the School of Medicine and Professor of Pathology and of Microbiology and Immunology
On Partial Leave from 10/01/2024 To 12/05/2024Current Research and Scholarly InterestsThe goals of Dr. Galli's laboratory are to understand the regulation of mast cell and basophil development and function, and to develop and use genetic approaches to elucidate the roles of these cells in health and disease. We study both the roles of mast cells, basophils, and IgE in normal physiology and host defense, e.g., in responses to parasites and in enhancing resistance to venoms, and also their roles in pathology, e.g., anaphylaxis, food allergy, and asthma, both in mice and humans.
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Leonor García-Bayona
Assistant Professor of Microbiology and Immunology
Current Research and Scholarly InterestsThe human microbiome is evolving rapidly (i.e. over our lifetimes) following changes in modern lifestyles, especially in industrialized countries. The García-Bayona lab seeks to understand how horizontal gene transfer shapes interactions within the human intestinal microbiota and what the implications of this widespread phenomenon are for community properties relevant to human health (for example, the ability of the gut community to recover after antibiotic treatment). There is currently only a superficial understanding of the different cellular roles of most exchanged genes, the mechanisms governing their spread and their effect community dynamics. Our lab works on bridging the existing gap between the current systems-level observational studies and a mechanistic understanding through bacterial genetics and physiology. We take a bottom-up approach (from genes to communities), incorporating genetics, metagenomics, population analyses and experimental evolution in tractable bacterial consortia.
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Matthias Garten
Assistant Professor of Microbiology and Immunology and of Bioengineering
BioMatthias Garten, Ph.D., is an assistant professor in the department of Immunology and Microbiology and the department of Bioengineering. He is a membrane biophysicist who is driven by the question of how the malaria parasite interfaces with its host-red blood cell, how we can use the unique mechanisms of the parasite to treat malaria and to re-engineer cells for biomedical applications.
He obtained a physics master's degree from the Dresden University of Technology, Germany with a thesis in the laboratory of Dr. Petra Schwille and his Ph.D. life sciences from the University Paris Diderot, France through his work in the lab of Dr. Patricia Bassereau (Insitut Curie) investigating electrical properties of lipid membranes and protein - membrane interactions using biomimetic model systems, giant liposomes and planar lipid membranes.
In his post-doctoral work at the National Institutes of Health, Bethesda in the laboratory of Dr. Joshua Zimmerberg, he used molecular, biophysical and quantitative approaches to research the malaria parasite. His work led to the discovery of structure-function relationships that govern the host cell – parasite interface, opening research avenues to understand how the parasite connects to and controls its host cell. -
Jeffrey S. Glenn, M.D., Ph.D.
Joseph D. Grant Professor and Professor of Microbiology and Immunology
Current Research and Scholarly InterestsDr. Glenn's primary interest is in molecular virology, with a strong emphasis on translating this knowledge into novel antiviral therapies. Other interests include exploitation of hepatic stem cells, engineered human liver tissues, liver cancer, and new biodefense antiviral strategies.