School of Medicine
Showing 1,551-1,560 of 5,029 Results
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Natalia Gomez-Ospina
Assistant Professor of Pediatrics (Genetics)
Current Research and Scholarly InterestsDr. Gomez-Ospina is a physician scientist and medical geneticist with a strong interest in the diagnosis and management of genetic diseases.
1) Lysosomal storage diseases:
Her research program is on developing better therapies for a large class of neurodegenerative diseases in children known as lysosomal storage disorders. Her current focus is on developing genome editing of hematopoietic stem cells as a therapeutic approach for these diseases beginning with Mucopolysaccharidosis type 1 and Gaucher disease. She established a genetic approach where therapeutic proteins can be targeted to a single well-characterized place in the genome known as a safe harbor. This approach constitutes a flexible, “one size fits all” approach that is independent of specific genes and mutations. This strategy, in which the hematopoietic system is commandeered to express and deliver therapeutic proteins to the brain can potentially change the current approaches to treating childhood neurodegenerative diseases and pave the way for alternative therapies for adult neurodegenerative disorders such as Alzheimer’s and Parkinson’s disease
2) Point of care ammonia testing
She also works in collaboration with other researchers at Stanford to develop point-of-care testing for serum ammonia levels. Such device will greatly improve the quality of life of children and families with metabolic disorders with hyperammonemia.
3) Gene discovery
Dr Gomez-Ospina lead a multi-institutional collaboration resulting in the discovery of a novel genetic cause of neonatal and infantile cholestatic liver disease. She collaborated in the description of two novel neurologic syndromes caused by mutations in DYRK1 and CHD4.
For more information go to our website:
https://www.gomezospina.com/ -
Julie Good, MD
Clinical Professor, Anesthesiology, Perioperative and Pain Medicine
Clinical Professor (By courtesy), PediatricsCurrent Research and Scholarly InterestsJulie's academic interests include pediatric palliative care, pain and symptom management for children with life-threatening illness, medical acupuncture, and meaning in medicine (the humanistic side of doctoring)
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Zinaida Good, Ph.D.
Assistant Professor of Medicine (Immunology and Rheumatology)
Current Research and Scholarly InterestsOur laboratory integrates cutting-edge synthetic biology, immunology, and machine learning to engineer T cell therapies for cancer and autoimmune diseases. We have 3 research areas:
- Analysis of clinical single-cell and spatial transcriptomics datasets from T cell therapy trials to identify mechanisms of resistance
- Building AI systems to generate T cell designs predicted to improve patient outcomes
- Genetic screens of novel T cell designs in models that mimic key mechanisms of resistance -
Alex J Goodell
Clinical Assistant Professor, Anesthesiology, Perioperative and Pain Medicine
BioAnesthesiologist and internist interested in artificial intelligence and large language models in medicine. Currently, my primary focus is on developing and evaluating applications of large language models to improve the "user experience" of patients (who spend too much time fighting the system that is tasked with healing them) and doctors (who spend too much time fighting the system that is supposed to help them heal others).
Interests:
- Benchmarking LLMs as clinical calculators
- Medical summarization by LLMs
- Agentic /tool-using language models
- GenerativeAI for Medical Education and Simulation
- Data equity in LLMs
- Novel benchmarks for clinical LLMs, including simulation
- Participatory research, open-source software
I'm a Clinical Scholar in the Dept of Anesthesiology and a Post-Doctoral Fellow in Anesthesiology / Biomedical Data Science in the lab of Nima Aghaeepour.
I completed medical school at the UC Berkeley - UCSF Joint Medical Program, followed by the Combined Internal Medicine/Anesthesiology Residency at the Stanford School of Medicine, and a fellowship in Anesthesia Informatics at the Stanford AIM Lab. -
Miriam B. Goodman
Mrs. George A. Winzer Professor of Cell Biology
Current Research and Scholarly InterestsWe study the molecular events that give rise to the sensation of touch and chemical stressors that compromise touch sensation in C. elegans. To do this, we use a combination of quantitative behavioral analysis, genetics, in vivo electrophysiology, and heterologous expression of ion channels. We collaborate with physicists and other physiologist to expand our experimental research.
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Steven Goodman
Professor of Epidemiology and Population Health, of Medicine (Primary Care and Population Health) and, by courtesy, of Health Policy
Current Research and Scholarly InterestsI study issues relating to the representation and measurement of evidence in medical research and determinants of the reliability of biomedical research findings. I also do work in evidence synthesis, comparative effectiveness research, and the ethics of clinical research.
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Stuart Goodman, MD, PhD
The Robert L. and Mary Ellenburg Professor of Surgery and Professor, by courtesy, of Bioengineering
Current Research and Scholarly InterestsAs an academic orthopaedic surgeon, my interests center on adult reconstructive surgery, arthritis surgery, joint replacement, biomaterials, biocompatibility, tissue engineering, mesenchymal stem cells. Collaborative clinical, applied and basic research studies are ongoing.
