School of Medicine
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Ragini Adams
Clinical Assistant Professor, Pediatrics - Hematology & Oncology
Current Research and Scholarly InterestsCirculating tumor DNA (ctDNA) is DNA that is released by tumor cells into the blood of the host; it is a fraction of all the cell free DNA (cfDNA) that is present. Because ctDNA contains the mutations of the original tumor, it is detectable using next generation sequencing and is an accurate surrogate measure of tumor burden. Therefore, ctDNA is an emerging biomarker in Hodgkin Lymphoma (HL) that is specific, quantifiable, and can be measured by noninvasive means. Using ctDNA to explore the genetic landscape of pediatric HL and monitor the response of these patients to therapy has never been done before and is my current focus of study.
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Catherine Aftandilian
Clinical Associate Professor, Pediatrics - Hematology & Oncology
Current Research and Scholarly InterestsI conduct clinical research on the prevention, early diagnosis, and treatment of infectious complications in pediatric patients with leukemia.