School of Medicine
Showing 281-290 of 341 Results
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Francesca Briganti
Instructor, Cardiovascular Institute
Current Research and Scholarly InterestsOne gene can lead to the production of many different RNA isoforms via mechanisms such as alternative promoter usage, splicing, and polyadenylation. The functional significance of many of these isoforms, their impact on cell physiology, and their regulation remain mostly controversial. Understanding the functional consequences of transcript heterogeneity will improve our understanding of gene expression regulation, broadening our ability to intervene when mutations that interfere with this regulation cause human disease.
My goal is to become an independent researcher leading an academic lab that focuses on better understanding human tissue-specific post-transcriptional regulation of gene expression and developing mechanism-based therapeutics. My general strategy is to study the function of regulatory genes and their deregulation in human disease. My specific approach is to understand the molecular mechanisms by which disease-causing mutations alter the gene function and lead to human disease. My hypothesis is that a detailed understanding of the relationship between the gene's molecular function and the disease mechanism will allow the development of first-in-class, personalized therapeutic strategies that target the disease mechanisms rather than manage symptoms independently of disease etiology. -
John Brock-Utne
Professor (Clinical) of Anesthesia, Emeritus
Current Research and Scholarly InterestsA large variety of clinical research including new non-invasive warming technology, temperature measurement during anesthesia, new non-pulsetile oximetry, monitoring of systemic ischemia, new technology to be used in anesthesia, airway management, and operating room waste
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Jay B. Brodsky
Professor (Clinical) of Anesthesiology, Perioperative and Pain Medicine, Emeritus
Current Research and Scholarly InterestsClinical aspects of anesthesia for non-cardiac thoracic surgery including lung separation techniques, management of one-lung ventilation and post-thoracotomy analgesia.
Anesthesia for the morbidly obese patient' bariatric surgery -
Jessica Brodt
Clinical Associate Professor, Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly InterestsClinical Education
Regional Anesthesia for Cardiothoracic Enhanced Recovery (RACER)
Anesthesia for transcatheter and electrophyiology procedures -
Laura Brodzinsky
Clinical Associate Professor, Obstetrics & Gynecology - Maternal Fetal Medicine
Current Research and Scholarly InterestsSpecial interest in women with vulvodynia and other genital pain disorders.
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Helen Bronte-Stewart, MD, MS
John E. Cahill Family Professor, Professor of Neurology (Adult Neurology) and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsMy research focus is human motor control and brain pathophysiology in movement disorders. Our overall goal is to understand the role of the basal ganglia electrical activity in the pathogenesis of movement disorders. We have developed novel computerized technology to measure fine, limb and postural movement. With these we are measuring local field potentials in basal ganglia nuclei in patients with Parkinson's disease and dystonian and correlating brain signalling with motor behavior.
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James D. Brooks
Keith and Jan Hurlbut Professor
Current Research and Scholarly InterestsWe use genomic approaches to identify disease biomarkers. We are most interested in translating biomarkers into clinical practice in urological diseases with a particular focus in cancer.
