School of Medicine
Showing 21-30 of 44 Results
Baker Family Director of Stanford ChEM-H, Anne T. and Robert M. Bass Professor in the School of Humanities and Sciences and Professor, by courtesy, of Chemical and Systems Biology and of Radiology
BioProfessor Carolyn Bertozzi's research interests span the disciplines of chemistry and biology with an emphasis on studies of cell surface sugars important to human health and disease. Her research group profiles changes in cell surface glycosylation associated with cancer, inflammation and bacterial infection, and uses this information to develop new diagnostic and therapeutic approaches, most recently in the area of immuno-oncology.
Dr. Bertozzi completed her undergraduate degree in Chemistry at Harvard University and her Ph.D. at UC Berkeley, focusing on the chemical synthesis of oligosaccharide analogs. During postdoctoral work at UC San Francisco, she studied the activity of endothelial oligosaccharides in promoting cell adhesion at sites of inflammation. She joined the UC Berkeley faculty in 1996. A Howard Hughes Medical Institute Investigator since 2000, she came to Stanford University in June 2015, among the first faculty to join the interdisciplinary institute ChEM-H (Chemistry, Engineering & Medicine for Human Health). She is now the Baker Family Director of Stanford ChEM-H.
Named a MacArthur Fellow in 1999, Dr. Bertozzi has received many awards for her dedication to chemistry, and to training a new generation of scientists fluent in both chemistry and biology. She has been elected to the Institute of Medicine, National Academy of Sciences, and American Academy of Arts and Sciences; and received the Lemelson-MIT Prize, the Heinrich Wieland Prize, the ACS Award in Pure Chemistry, and the Chemistry of the Future Solvay Prize, among others.
The Bertozzi Group develops chemical tools to study the glycobiology underlying diseases such as cancer, inflammation, tuberculosis and most recently COVID-19. She is the inventor of "bioorthogonal chemistry", a class of chemical reactions compatible with living systems that enable molecular imaging and drug targeting. Her group also developed new therapeutic modalities for targeted degradation of extracellular biomolecules, such as antibody-enzyme conjugates and Lysosome Targeting Chimeras (LYTACs). As well, her group studies NGly1 deficiency, a rare genetic disease characterized by loss of the human N-glycanase.
Several of the technologies developed in the Bertozzi lab have been adapted for commercial use. Actively engaged with several biotechnology start-ups, Dr. Bertozzi cofounded Redwood Bioscience, Enable Biosciences, Palleon Pharmaceuticals, InterVenn Bio, OliLux Bio, Grace Science LLC and Lycia Therapeutics. She is also a member of the Board of Directors of Lilly.
Postdoctoral Scholar, Radiology
Current Research and Scholarly InterestsMy current research interests include medical image processing and multimodal data fusion and analysis for disease diagnosis.
Sandip Biswal, MD
Associate Professor of Radiology (Musculoskeletal Imaging)On Partial Leave from 08/25/2021 To 05/31/2022
Current Research and Scholarly InterestsThe management of individuals suffering from chronic pain is unfortunately limited by poor diagnostic tests and therapies. Our research group is interested in 'imaging pain' by using novel imaging techniques to study peripheral nociception and inflammation with the goal of accurately identifying the location of pain generators. We are developing new approaches with positron emission tomography (PET) and magnetic resonance imaging (MRI) (PET/MRI) and are currently in clinical trials.
Sr Res Scientist-Physical, Rad/Body MRI
Current Role at Stanford•Original research focusing on applications of MR guided Focused Ultrasound (MRgFUS) for ablative treatments of cancer and trans-cranial neurosurgical treatment of tremor.
•Developing new MRI imaging strategies and pulse sequence development of non-ablative applications of focused ultrasound, including MR Acoustic Radiation Force Imaging.
•Medical Physicist including ultrasound treatment planning and MRI imaging specialist of multiple ongoing human clinical trials, as well as clinical treatments at SHC, to image, treat, and monitor MRgFUS of bone metastases, soft tissue tumors of the extremities, uterine fibroids, and trans-cranial MRgFUS treatment of essential tremor.
•Bridge technical and clinical communication as a go between in collaborations with clinicians, interventional radiologists, imaging technologists, medical device companies, and research scientists, graduate students, and faculty.
Postdoctoral Scholar, Radiological Sciences Laboratory
BioDr. Marianne Black is a Postdoctoral Fellow in Radiology in the IMMERS (Incubator for Medical Mixed and Extended Reality), BMR (Body Magnetic Resonance) and JOINT (Joint and Osteoarthritis Imaging with Novel Technology) groups. Dr. Black currently works with with Drs. Brian Hargreaves, Bruce Daniel and Garry Gold. Her postdoctoral research is focused on imaging to detect and treat musculoskeletal disease. She is developing immersive mixed reality tools to improve surgical outcomes in orthopaedics.
Dr. Black’s PhD research under Drs. Marc Levenston, Brian Hargreaves and Garry Gold focused on the application and development of novel methods and analysis techniques for quantitative knee imaging using MRI and CT. Her work included leading a study measuring quantitative MRI parameters of ACL-injured subjects, and her analysis methods that built upon Dr. Hargreaves group’s previous analysis methods showed the ability to differentiate ACL-injured and healthy cartilage as early as 3-months post-surgery. Prior to attending Stanford, she completed her MASc at the University of British Columbia in Biomedical Engineering under Dr. Dave Wilson. Dr. Black's research studied the effect of wedge and slope in medical opening high tibial osteotomy on joint kinematics and tibiofemoral joint contact pressure. She also co-founded Arbutus Medical during this time, which develops orthopaedic medical devices for low-resource hospitals.
Associate Professor of Radiology (Pediatric Radiology) and, by courtesy, of Pediatrics
Current Research and Scholarly InterestsStudies on apoptotic cell death in vivo using the H MRS phenomenon.