School of Medicine
Showing 311-320 of 347 Results
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Anne Brunet
Michele and Timothy Barakett Endowed Professor
Current Research and Scholarly InterestsOur lab studies the molecular basis of longevity. We are interested in the mechanism of action of known longevity genes, including FOXO and SIRT, in the mammalian nervous system. We are particularly interested in the role of these longevity genes in neural stem cells. We are also discovering novel genes and processes involved in aging using two short-lived model systems, the invertebrate C. elegans and an extremely short-lived vertebrate, the African killifish N. furzeri.
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Axel Brunger
Professor of Molecular and Cellular Physiology, of Neurology and Neurological Sciences, of Photon Science and, by courtesy, of Structural Biology
Current Research and Scholarly InterestsOne of Axel Brunger's major goals is to decipher the molecular mechanisms of synaptic neurotransmitter release by conducting imaging and single-molecule/particle reconstitution experiments, combined with near-atomic resolution structural studies of the synaptic vesicle fusion machinery.
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Jennifer L. Bruno
Instructor, Psychiatry and Behavioral Sciences - Interdisciplinary Brain Sciences
Current Research and Scholarly InterestsDr. Bruno is a translational researcher at the interface of developmental cognitive neuropsychology and neurobiology. An overarching goal of her work is to understand developmental windows of vulnerability—periods of risk for falling off the trajectory of typical brain development. Her research utilizes genetics, brain imaging, and deep behavioral phenotyping to bridge computational science with clinical knowledge, translating cutting-edge science to solve problems of great clinical need.
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Douglas L. Brutlag
Professor of Biochemistry, Emeritus
Current Research and Scholarly InterestsMy primary interest is to understand the flow of information from the genome to the phenotype of an organism. This interest includes predicting the structure and function of genes and proteins from their primary sequence, predicting function from structure simulating protein folding and ligand docking, and predicitng disease from genome variations. These goals are the same as the goals of molecular biology, however, we use primarily computational approaches.
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Zev Bryant
Associate Professor of Bioengineering and, by courtesy, of Structural Biology
Current Research and Scholarly InterestsMolecular motors lie at the heart of biological processes from DNA replication to vesicle transport. My laboratory seeks to understand the physical mechanisms by which these nanoscale machines convert chemical energy into mechanical work.
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Vivek P. Buch, MD
Assistant Professor of Neurosurgery
BioDr. Buch is a neurosurgeon with fellowship training in epilepsy, functional, and minimally invasive neurosurgery. He is an Assistant Professor of Neurosurgery, and Christina and Hamid Moghadam Faculty Scholar at Stanford University.
Dr. Buch focuses his expertise on the open and minimally invasive treatment of epilepsy, low grade brain tumors, movement and neuropsychiatric disorders, facial and body pain syndromes, and other complex neurological conditions. He uses advanced and innovative techniques to treat both adult and pediatric patients. For each patient, he develops a personalized care plan that is designed to be both comprehensive and compassionate.
Dr. Buch has conducted extensive research. His career goal is to develop restorative bioengineering approaches for complex neurocognitive, neurodevelopmental, and neuropsychiatric disorders. He is creating network-neuroprosthetics and focused ultrasound delivery mechanisms for precision cellular, gene, and molecular therapies to restore abnormal brain circuit function in these vulnerable patient populations. He is further pioneering novel intraoperative technologies including personalized network-based targeting, holographic mixed reality, and artificial intelligence platforms for minimally invasive cranial surgery.
He has co-authored articles on his research discoveries in Nature Medicine, Neuron, Brain, Annals of Surgery, Frontiers in Neuroscience, Epilepsia, Brain Stimulation, Stereotactic and Functional Neurosurgery, Surgical Innovation, Frontiers in Surgery, Journal of Neurosurgery, and many other journals. Articles focus on developing novel network control theory applications to human brain functions and new techniques and technologies to enhance neurosurgical effectiveness and patient outcomes.
He is the Section Editor for NEUROSURGERY, and a guest editor for Surgical Innovation and Brain Sciences. He also has co-authored chapters in the books Neurosurgical Atlas, Operative Techniques in Epilepsy Surgery, Deep Brain Stimulation, and The Encyclopedia of Medical Robotics.
Dr. Buch has presented the findings of his research at the national conferences of numerous professional associations. Among them are the American Association of Neurological Surgeons, Society for Neuroscience, Congress of Neurological Surgeons, and Society for Imaging Informatics in Medicine. Topics include understanding network mechanisms of cognitive control and advances in the use of augmented reality technology to enhance neurosurgical approaches.
For his clinical, research, and academic achievements. Dr. Buch has earned many honors. He has won awards from the American Association of Neurological Surgeons, American Roentgen Ray Society, Congress of Neurological Surgeons, and National Institutes of Health.
Dr. Buch is a member of the American Association of Neurological Surgeons, Congress of Neurological Surgeons, World Society for Stereotactic and Functional Neurosurgery, American Association of Stereotactic and Functional Neurosurgery, and Alpha Omega Alpha Medical Honor Society.
He holds patents on such topics as artificial intelligence systems designed to help guide surgery and neural control signals for behavioral modification and closed-loop stimulation therapy.
Essential tremor patient story: https://www.youtube.com/watch?v=fV6BzyU9b3c
Parkinson's disease patient story: https://www.youtube.com/watch?v=vAKP7SRKs08
Epilepsy patient story: https://www.youtube.com/watch?v=HXy-gXg0t94&t=3s
Deep brain stimulation treatment: https://www.youtube.com/watch?v=xLgEcb447gA&t=1s
Laser interstitial thermal therapy treatment: https://www.youtube.com/watch?v=z-nRUMbs2kY&t=2s
MR-guided focused ultrasound treatment: https://www.youtube.com/watch?v=3Bwq2YxD9eU
