School of Medicine


Showing 41-51 of 51 Results

  • David Drover

    David Drover

    Professor of Anesthesiology, Perioperative and Pain Medicine (MSD)
    On Partial Leave from 05/01/2024 To 01/31/2025

    Current Research and Scholarly InterestsField of clinical pharmacology. This involves analysis of what the body does to a drug (pharmacokinetics) and how exactly a specific drug affects the body (pharmacodynamics). His research starts at the level of new drug development with detailed analysis of the pharmacokinetics and pharmacodynamics of a medication.

  • Maurice L. Druzin

    Maurice L. Druzin

    Professor of Obstetrics and Gynecology (Maternal Fetal Medicine and Obstetrics) and, by courtesy, of Pediatrics

    Current Research and Scholarly InterestsAntepartum and intrapartum fetal monitoring Prenatal diagnosis Medical complications of pregnancy, particularly: SLE, hypertension, diabetes, malignancy A.

  • Justin Du Bois

    Justin Du Bois

    Henry Dreyfus Professor of Chemistry and Professor, by courtesy, of Chemical and Systems Biology

    BioResearch and Scholarship

    Research in the Du Bois laboratory spans reaction methods development, natural product synthesis, and chemical biology, and draws on expertise in molecular design, molecular recognition, and physical organic chemistry. An outstanding goal of our program has been to develop C–H bond functionalization processes as general methods for organic chemistry, and to demonstrate how such tools can impact the logic of chemical synthesis. A second area of interest focuses on the role of ion channels in electrical conduction and the specific involvement of channel subtypes in the sensation of pain. This work is enabled in part through the advent of small molecule modulators of channel function.

    The Du Bois group has described new tactics for the selective conversion of saturated C–H to C–N and C–O bonds. These methods have general utility in synthesis, making possible the single-step incorporation of nitrogen and oxygen functional groups and thus simplifying the process of assembling complex molecules. To date, lab members have employed these versatile oxidation technologies to prepare natural products that include manzacidin A and C, agelastatin, tetrodotoxin, and saxitoxin. Detailed mechanistic studies of metal-catalyzed C–H functionalization reactions are performed in parallel with process development and chemical synthesis. These efforts ultimately give way to advances in catalyst design. A long-standing goal of this program is to identify robust catalyst systems that afford absolute control of reaction selectivity.

    In a second program area, the Du Bois group is exploring voltage-gated ion channel structure and function using the tools of chemistry in combination with those of molecular biology, electrophysiology, microscopy and mass spectrometry. Much of this work has focused on studies of eukaryotic Na and Cl ion channels. The Du Bois lab is interested in understanding the biochemical mechanisms that underlie channel subtype regulation and how such processes may be altered following nerve injury. Small molecule toxins serve as lead compounds for the design of isoform-selective channel modulators, affinity reagents, and fluorescence imaging probes. Access to toxins and modified forms thereof (including saxitoxin, gonyautoxin, batrachotoxin, and veratridine) through de novo synthesis drives studies to elucidate toxin-receptor interactions and to develop new pharmacologic tools to study ion channel function in primary cells and murine pain models.

  • Dawn Duane

    Dawn Duane

    Clinical Professor, Neurology
    Clinical Professor (By courtesy), Pediatrics

    Current Research and Scholarly InterestsI am a general pediatric neurologist. My interest is in clinical diagnosis and treatment of common neurologic diseases in pediatric patients and teaching feature doctors, neurologists and pediatric neurologists about pediatric neurology.

  • Anne Dubin

    Anne Dubin

    Endowed Professor of Pediatric Cardiology

    Current Research and Scholarly InterestsArrhythmia management in pediatric heart failure, especially resynchronization therapy in congenital heart disease,Radio frequency catheter ablation of pediatric arrhythmias,

  • Alexander Dunn

    Alexander Dunn

    Professor of Chemical Engineering

    Current Research and Scholarly InterestsMy lab is deeply interested in uncovering the physical principles that underlie the construction of complex, multicellular animal life.

  • James Dunn

    James Dunn

    Professor of Surgery (Pediatric Surgery) and, by courtesy, of Bioengineering

    Current Research and Scholarly InterestsIntestinal lengthening for short bowel syndrome
    Intestinal stem cell therapy for intestinal failure
    Skin derived precursor cell therapy for enteric neuromuscular dysfunction
    Intestinal tissue engineering

  • Ram S Duriseti

    Ram S Duriseti

    Clinical Associate Professor, Emergency Medicine

    BioRam's Doctoral background and academic interests are in the computational modeling of complex decisions, algorithm design and implementation, and data driven decision making. Outside of clinical work, his main competencies in this regard are software development, algorithm design and implementation, cost-effectiveness analysis, and decision analysis through computational models. He has also collaborated with industry to create and deploy operation specific software involving statistical computing and reasoning under inference. He has been practicing clinical Emergency Medicine in both community and academic settings for over 20 years.

    https://www.shiftgen.com/about
    https://www.linkedin.com/in/ram-duriseti-991614/

  • Gozde Durmus

    Gozde Durmus

    Assistant Professor (Research) of Radiology (Molecular Imaging Program at Stanford)

    Current Research and Scholarly InterestsDr. Durmus' research focuses on applying micro/nano-technologies to investigate cellular heterogeneity for single-cell analysis and personalized medicine. At Stanford, she is developing platform technologies for sorting and monitoring cells at the single-cell resolution. This magnetic levitation-based technology is used for wide range of applications in medicine, such as, label-free detection of circulating tumor cells (CTCs) from blood; high-throughput drug screening; and rapid detection and monitoring of antibiotic resistance in real-time. During her PhD, she has engineered nanoparticles and nanostructured surfaces to decrease antibiotic-resistant infections.