School of Medicine
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Seunggu J Han
Clinical Associate Professor, Neurosurgery
BioDr. Seunggu Jude Han is a Clinical Associate Professor in Neurological Surgery and the Chief of Neurosurgery at the Palo Alto VA. He completed his undergraduate studies at University of California, Los Angeles, and received his medical degree from University of California, San Francisco (UCSF). Dr. Han completed his residency training in Neurosurgery at UCSF, as well as a fellowship in Neuro-Oncology at UCSF.
Dr. Han joins Stanford from Oregon Health and Science University (OHSU), where he served as an assistant professor of Neurological Surgery, the Associate Program Director of the Neurosurgery residency training program, and Surgical Director of Neuro-Oncology at the Knight Cancer Institute.
He remains passionate about underserved care and medical education. His clinical and academic interests include brain tumors, brain mapping, and quality improvement. Dr. Han has published over 100 peer-reviewed articles.
Associate Professor (Research) of Neurosurgery, of Medicine (Biomedical Informatics) and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly InterestsMy current research focuses on understanding the genetic and environmental etiology of complex disease and developing and evaluating efficient screening strategies based on etiological understanding. The areas of my research interests include statistical genetics, molecular epidemiology, cancer screening, health policy modeling, and risk prediction modeling. I have developed various statistical methods to analyze high-dimensional data to identify genetic and environmental risk factors and their interactions for complex disease.
Ciara Harraher, MD
Clinical Professor, Neurosurgery
Current Research and Scholarly InterestsI am interested in medical education and I am an Associate in the Practice of Medicine and doctoring with CARE ( E4C) Program. I am also interested in surgical outcomes research and I am involved in clinical trials studying brain tumors and stroke. I have also presented internationally on issues related to improving diversity in Neurosurgery.
Odette Harris, MD, MPH
Paralyzed Veterans of America Professor of Spinal Cord Injury Medicine
Current Research and Scholarly InterestsTraumatic brain injury with a focus on epidemiology and outcomes.
Melanie Hayden Gephart
Professor of Neurosurgery and, by courtesy, of Neurology
BioI am a brain tumor neurosurgeon, treating patients with primary and metastatic brain tumors. I treat patients with malignant and benign tumors, including glioma, brain metastases, meningioma, and vestibular schwannomas. I direct the Stanford Brain Tumor Center and the Stanford Brain Metastasis Consortium, collaborative unions of physicians and scientists looking to improve our understanding and treatment of brain tumors. My laboratory seeks greater understanding of the mechanisms driving tumorigenesis and disease progression in malignant brain tumors. We study how rare cancer cell populations survive and migrate in the brain, inadvertently supported by native brain cells. We develop novel cell free nucleic acid biomarkers to track brain cancer treatment response, relapse, and neurotoxicity. Our bedside-to-bench-to-bedside research model builds on a foundation of generously donated patient samples, where we test mechanisms of brain cancer growth, develop novel pre-clinical models that reliably recapitulate the human disease, and facilitate clinical trials of new treatments for patients with brain cancer.
Jeremy J. Heit, MD, PhD
Associate Professor of Radiology (Neuroimaging and Neurointervention) and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsOur research seeks to advance our understanding of cerebrovascular disease and to develop new minimally invasive treatments for these diseases. We study ischemic and hemorrhagic stroke, cerebral aneurysms, delayed cerebral ischemia, cerebral arteriovenous malformations (AVMs), dural arteriovenous fistulae, and other vascular diseases of the brain. We use state-of-the-art neuroimaging techniques to non-invasively study these diseases, and we are developing future endovascular technologies to advance neurointerventional surgery.
Jaimie Henderson, MD
John and Jene Blume - Robert and Ruth Halperin Professor, Professor of Neurosurgery and, by courtesy, of Neurology
Current Research and Scholarly InterestsMy research interests encompass several areas of stereotactic and functional neurosurgery, including frameless stereotactic approaches for therapy delivery to deep brain nuclei; cortical physiology and its relationship to normal and pathological movement; brain-computer interfaces; and the development of novel neuromodulatory techniques for the treatment of movement disorders, epilepsy, pain, and other neurological diseases.
Karen G. Hirsch, MD
Associate Professor of Neurology and, by courtesy, of Neurosurgery
Current Research and Scholarly InterestsDr. Karen G. Hirsch cares for critically ill patients with neurologic disorders in the intensive care unit. Dr. Hirsch's research focuses on using continuous and discrete multi-modal data to develop phenotypes and identify signatures of treatment responsiveness in patients with coma after cardiac arrest. She is the Co-PI of PRECICECAP (PRecision Care In Cardiac ArrEst - ICECAP, NINDS R01 NS119825-01) and works closely with collaborators in data science at Stanford and with industry partners to apply machine learning analyses to the complex multi-modal ICU data. Dr. Hirsch also studies neuro-imaging in post-cardiac arrest coma and traumatic brain injury.
Additional research interests include a broad array of topics and Dr. Hirsch greatly appreciates the importance of team science and collaboration. Along with colleagues in Biomedical Ethics, Dr. Hirsch studies brain death and organ donation with a focus on ethical challenges and prediction models. Along with colleagues in Cardiac Anesthesia and Cardiothoracic Surgery, Dr. Hirsch studies neurologic outcomes in patients on mechanical circulatory support including ECMO.
Dr. Hirsch is broadly interested in improving neurologic outcomes after acute brain injury and identifying early phenotypes to guide precision medicine in neurocritical care, especially in patients with post-cardiac arrest brain injury.
Yusuke Hori, MD
Clinical Instructor, Neurosurgery
BioDr. Hori received his MD from Sapporo Medical University, Japan, and during that time he served as a Medical Student Research Fellow in the Department of Pharmacology. He explored the functional role of the SIRT1 gene, a longevity-associated gene, and its association with various conditions such as muscular dystrophy. He also completed a Visiting Student Research Fellowship at the Health Sciences University of Hokkaido and participated in Human Genetics projects focusing on an association between the 27-bp deletion and 538G>A mutation in the ABCC11 Gene.
After graduating from medical school, Dr. Hori completed a neurosurgery residency at National Hospital Organization Okayama Medical Center in Japan. Subsequently, he completed a Stereotactic and Functional Neurosurgery Fellowship and then a Neurosurgical Oncology and Radiosurgery Fellowship at The Cleveland Clinic. He also completed an International Neurosurgery Fellowship at Boston Children's Hospital, Harvard Medical School. In 2022, he moved to Stanford University as a postdoctoral fellow, and under the supervision of Dr. Anca Pasca, he participated in brain organoid research focusing on hypoxic brain injuries.
Since July 2023, Dr. Hori has been working as a Clinical Instructor (Neurosurgical Oncology and Radiosurgery) in the Department of Neurosurgery at Stanford under the supervision of Dr. Steven D. Chang. His clinical interests include malignant brain and spine tumors in both adult and pediatric patients. His clinical research focuses on the application of minimally invasive treatments such as laser interstitial thermal therapy, focused ultrasound, and radiosurgery to treat various neurosurgical conditions. His current lab research aims to develop an organoid model for radiation-induced brain injuries and a high-throughput screening platform to identify novel therapeutic compounds, for which he received a Clinician Educator Grant from Stanford University Maternal and Child Health Research Institute. Outside of medicine, he enjoys playing music including guitar and drums.