School of Medicine
Showing 21-40 of 49 Results
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Nasim Sabery Khavari
Clinical Associate Professor, Pediatrics - Gastroenterology
Current Research and Scholarly InterestsPediatric Gastroenterology, Celiac Disease, Nutrition in Celiac Disease
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Paul A. Khavari, MD, PhD
Carl J. Herzog Professor of Dermatology in the School of Medicine
Current Research and Scholarly InterestsWe work in epithelial tissue as a model system to study stem cell biology, cancer and new molecular therapeutics. Epithelia cover external and internal body surfaces and undergo constant self-renewal while responding to diverse environmental stimuli. Epithelial homeostasis precisely balances stem cell-sustained proliferation and differentiation-associated cell death, a balance which is lost in many human diseases, including cancer, 90% of which arise in epithelial tissues.
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Chaitan Khosla
Wells H. Rauser and Harold M. Petiprin Professor and Professor of Chemistry and, by courtesy, of Biochemistry
Current Research and Scholarly InterestsResearch in this laboratory focuses on problems where deep insights into enzymology and metabolism can be harnessed to improve human health.
For the past two decades, we have studied and engineered enzymatic assembly lines called polyketide synthases that catalyze the biosynthesis of structurally complex and medicinally fascinating antibiotics in bacteria. An example of such an assembly line is found in the erythromycin biosynthetic pathway. Our current focus is on understanding the structure and mechanism of this polyketide synthase. At the same time, we are developing methods to decode the vast and growing number of orphan polyketide assembly lines in the sequence databases.
For more than a decade, we have also investigated the pathogenesis of celiac disease, an autoimmune disorder of the small intestine, with the goal of discovering therapies and related management tools for this widespread but overlooked disease. Ongoing efforts focus on understanding the pivotal role of transglutaminase 2 in triggering the inflammatory response to dietary gluten in the celiac intestine. -
Peter S. Kim
Virginia and D. K. Ludwig Professor of Biochemistry
On Partial Leave from 09/01/2023 To 06/30/2024Current Research and Scholarly InterestsWe are studying the mechanism of viral membrane fusion and its inhibition by drugs and antibodies. We use the HIV envelope protein (gp120/gp41) as a model system. Some of our studies are aimed at creating an HIV vaccine. We are also characterizing protein surfaces that are referred to as "non-druggable". These surfaces are defined empirically based on failure to identify small, drug-like molecules that bind to them with high affinity and specificity.
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Seung K. Kim M.D., Ph.D.
KM Mulberry Professor, Professor of Developmental Biology, of Medicine (Endocrinology) and, by courtesy, of Pediatrics (Endocrinology)
Current Research and Scholarly InterestsWe study the development of pancreatic islet cells using molecular, embryologic and genetic methods in several model systems, including mice, pigs, human pancreas, embryonic stem cells, and Drosophila. Our work suggests that critical factors required for islet development are also needed to maintain essential functions of the mature islet. These approaches have informed efforts to generate replacement islets from renewable sources for diabetes.
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Alaina Kipps
Clinical Professor, Pediatrics - Cardiology
BioDr. Kipps grew up in Santa Cruz, California and completed her medical degree at Harvard Medical School in 2003. After general pediatrics residency at Stanford, she completed pediatric cardiology fellowship at Boston Children’s Hospital from 2006 to 2009. Having concentrated her final year of fellowship on echocardiography, she came west to practice at University of California, San Francisco until 2012. She was recruited back to Stanford in 2012 to become the medical director for acute care cardiology and she remained active in the echocardiography laboratory until 2016. In 2014 she co-founded the PAC³ network with Nicolas Madsen and co-directs this today. Her academic focus is in clinical effectiveness and quality improvement science, and she completed her Masters of Science in Epidemiology at Harvard School of Public Health in 2016. Her other significant interest is in teaching; she co-directs the pediatric residency cardiology rotation at Stanford.
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Varvara A. Kirchner
Associate Professor of Surgery (Abdominal Transplantation) and, by courtesy, of Pediatrics
BioDr. Kirchner completed her medical school, surgical residency and multi-organ transplant fellowship in adult and pediatric liver, pancreas, kidney transplantation and total pancreatectomy with islet auto-transplantation at the University of Minnesota. She underwent further training in living donor liver transplantation and hepatobiliary surgery at the Asan Medical Center, Seoul, South Korea. Her clinical practice involves living and deceased donor liver and kidney transplantation in adult and pediatric patients as well as total pancreatectomy with islet auto-transplantation for patients with chronic and acute recurrent pancreatitis. She currently serves as Surgical Director of the Islet Cell Auto-Transplant at Stanford Children’s and Associate Director of the Living Donor Liver Transplant Program at the Division of Abdominal Transplantation. Dr. Kirchner’s research focuses on the biology of aging, cellular and solid organ transplantation. Her specific interests are in auto-islet transplantation, iPSC-derived hepatocyte therapies and liver regeneration. Dr. Kirchner's research on the impact of donor age on generation of iPSC-derived hepatocyte-like cells is supported by the NIA K08 Faculty Development Award. She is an active member of the American Society of Transplant Surgeons and the International Liver Transplantation Society.
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Jonathan D Klein
Marron and Mary Elizabeth Kendrick Professor of Pediatrics
Current Research and Scholarly InterestsMy studies address:
1. Confidentiality and Access to Care studies of confidential time during well-visits and policy analyses addressing quality of care and health systems capacity for adolescents and young adults in the US and globally; and,
2, Tobacco, nicotine, and second-hand smoke studies of primary care counseling to reduce nicotine addiction in adolescents and programs to engage medical specialty groups in secondhand smoke clinical and policy interventions. -
Teri Klein
Professor (Research) of Biomedical Data Science, of Medicine (BMIR) and, by courtesy, of Genetics
Current Research and Scholarly InterestsCo-founder, Pacific Symposium on Biocomputing
NIEHS, Site Visit Reviewer
NIH, Study Section Reviewer -
Joshua W. Knowles
Associate Professor of Medicine (Cardiovascular Medicine)
Current Research and Scholarly InterestsGenetic basis of coronary disease
Genetic basis of insulin resistance
Familial Hypercholesterolemia (FH) -
Juliet Klasing Knowles
Assistant Professor of Neurology (pediatric Neurology) and of Pediatrics
Current Research and Scholarly InterestsThe Knowles lab studies how white matter structure changes in different forms of epilepsy, and how aberrant white matter structure, in turn, shapes neuronal network function. In mouse models, we use a variety of innovative tools including neurophysiology, quantitative EEG, behavior, histological measures of white matter structure and MR imaging. We also conduct clinical research to study white matter abnormalities in children with epilepsy.
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Justin M Ko, MD, MBA
Clinical Professor, Dermatology
BioDr. Ko joined Stanford Medicine in 2012 and serves as Director and Chief of Medical Dermatology for Stanford Health Care (SHC) while also spearheading the dermatology department's efforts around network development, digital health, quality/safety/performance improvement, and value-based care. He is active in a number of leadership roles within the organization including as an Associate Chief Quality Officer and physician dyadic partner to the Chief Experience Offer, as well as co-chair of the Clinic Advisory Council, a forum of medical and executive leaders of Stanford Health Care’s Ambulatory clinics.
His passion for melanoma, early cancer detection, and improving care delivery drives his efforts and research around leveraging advances in machine learning and artifical intelligence to increase the breadth of populations that can be reached. He developed and runs a digital care delivery program at SHC, providing virtual visits for patients and remote consultations for referring clinicians. He conducts research on and engages in collaborations around interventions that layer advances in machine learning on digital health capabilities to enhance access, quality and value of dermatologic care and is a founder and leader of the Stanford Translational AI in Dermatology (TRAIND) group. He chairs the American Academy of Dermatology's Committee on Augmented Intelligence.
Dr. Ko has also been driven to find new treatments for alopecia areata, an immune-mediated condition that can progress to total hair loss through various clinical trials and translational research efforts. He sits on the clinical research advisory board of the National Alopecia Areata Foundation and is a founder and co-director of the Skin Innovation and Interventional Research Group (SIIRG) which conducts clinical and translational research on skin disease.
He graduated magna cum laude from Harvard University and worked in investment banking; mergers and acquisitions at JP Morgan before going on to earn a combined medical and business degree at Tufts University. During medical school, he was a member of the Alpha Omega Alpha honor society. Dr. Ko then performed his residency at the Harvard Dermatology Residency Training Program where he served as chief resident. -
Brian Kobilka
Hélène Irwin Fagan Chair of Cardiology
Current Research and Scholarly InterestsStructure, function and physiology of adrenergic receptors.
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Eric Kool
George A. and Hilda M. Daubert Professor of Chemistry
Current Research and Scholarly Interests• Design of cell-permeable reagents for profiling, modifying, and controlling RNAs
• Developing fluorescent probes of DNA repair pathways, with applications in cancer, aging, and neurodegenerative disease
• Discovery and development of small-molecule modulators of DNA repair enzymes, with focus on cancer and inflammation -
Ron Kopito
Professor of Biology
Current Research and Scholarly InterestsOur laboratory use state-of-the-art cell biological, genetic and systems-level approaches to understand how proteins are correctly synthesized, folded and assembled in the mammalian secretory pathway, how errors in this process are detected and how abnormal proteins are destroyed by the ubiquitin-proteasome system.
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Sheri Krams
Senior Associate Dean, Graduate Education and Postdoctoral Affairs and Professor of Surgery (Abdominal Transplantation)
Current Research and Scholarly InterestsResearch Interests: 1) NK Cell Responses to EBV, 2) Exosomes in Immune Responses, 3) Plasmacytoid Dendritic Cell-Mediated Graft Prolongation, 4)Transplant Immunology
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Elliot J. Krane
Professor of Anesthesiology, Perioperative and Pain Medicine (Pediatric Anesthesia) at the Stanford University Medical Center, Emeritus
Current Research and Scholarly InterestsThe management of pain in children using intraspinal opioids, regional anesthetics, and novel analgesic agents; cerebral and osmolar complications of diabetic ketoacidosis in children.
