School of Medicine
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Angelle Desiree LaBeaud
Associate Professor of Pediatrics (Infectious Diseases) and, by courtesy, of Health Research and Policy (Epidemiology) at the Lucile Salter Packard Children's Hospital
Current Research and Scholarly InterestsArthropod-borne viruses are emerging and re-emerging infections that are spreading throughout the world. Our laboratory investigates the epidemiology of arboviral infections, focusing on the burden of disease and the long-term complications on human health. In particular, Dr. LaBeaud investigates dengue, chikungunya, and Rift Valley fever viruses in Kenya, where outbreaks cause fever, arthritis, retinitis, encephalitis, and hemorrhagic fever. Our main research questions focus on the risk factors for arboviral infections, the development of diagnostic tests that can be administered in the field to quickly determine what kind of arboviral infection a person has, and the genetic and immunologic investigation of why different people respond differently to the same infection. Our long-term goals are to contribute to a deeper understanding of arboviral infections and their long-term health consequences and to optimize control strategies to prevent these emerging infections. Our laboratory also investigates the effects of antenatal and postnatal parasitic infections on vaccine responses, growth, and development of Kenyan children.
My lab at Stanford supports the field work that is ongoing in Kenya, but we also have several projects that are based locally. We strive to improve diagnostics of arboviral infections and are using Luminex technology to build a new screening assay. We also have created a Luminex based platform to assess vaccine responses against multiple pathogens.
Eileen B. Leary
Ph.D. Student in Epidemiology and Clinical Research, admitted Autumn 2017
Senior Manager of Clinical Research, Psych/Sleep Medicine
Current Role at StanfordSenior Manager of Clinical Research
Responsibilities included leading technical initiatives, writing grants/proposals, performing statistical analysis and power calculations for grant applications/publications, designing research studies/clinical trials, developing budgets, negotiating contracts, and actively building successful collaborations with internal and third party organizations.
•Project Director for the Stanford Technology Analytics and Genomics in Sleep (STAGES) study: a prospective study that will sleep related data on 30,000 sleep clinic patients (age 13 and up) including genetic and phenotypic data. Managed the study at the strategic level to ensure that the project progresses on time and on budget. Chair the Operations Committee, coordinated the development of the data management portal, provided high-level oversight for data collection, and managed the databases and servers for and secure storage and sharing.
• Helped department secure >40 million dollars in funding by directing the submission of 15 grant applications. Grants included an 18 million dollar family foundation grant to build a prospective cohort of 30k sleep clinic patients and a 7.85 million dollar NIH P01 grant to research the genetic, neurobiological, and immunological basis of type 1 narcolepsy.
• Project Director for the Alliance Sleep Questionnaire (ASQ): an online questionnaire that uses complex, branching logic to identify potential sleep disorders. Partnered with stakeholders from 5 sites to develop the ASQ’s content, conducted the pilot study, managed deployment, and integrated the new tool into the core workflow at Stanford’s Sleep Clinic. Responsible for the ongoing management of the ASQ (monitoring data acquisition and integrity, assessing data quality, developing scoring algorithms, and performing data analysis). To date, the ASQ has been completed by over 10,000 people, is critical for >10 research studies (including STAGES, Google baseline pilot), and has become standard of care at the Stanford Sleep Medicine Center.
• Database Architect/Administrator for the Stanford Sleep Cohort and Narcolepsy Cohort. Created system to link clinical, research, and sleep study data on >40,000 individuals including biological data on >5,000 narcolepsy cases and >15,000 controls. Optimized data security and operational effectiveness by providing technical expertise and developing both the schema and data dictionaries.
• Implemented and managed Stanford’s Multi-site PSG Triple Re-Score Project. Authored manual of operations for the Stanford Site, developed a partnership with Philips Respironics to streamline data-export of >500 studies, hired/managed scoring techs, produced final dataset, and provided regular updates to the project’s steering committee.
• Program and Technical Director of Stanford’s Accredited Sleep Technologist Education Program. Developed A-STEP’s course curriculum (including speakers and materials), managed all administrative requirements (enrollment and record keeping), and presented lectures on various topics ranging from sleep scoring to patient hook ups.
• Provided operational oversight for 8 clinical studies with sample sizes ranging from 40 to over 8,000.
• Authored/co-authored 30 manuscripts and abstracts published in scientific journals.
• Composed/managed >40 department active IRB protocols (involved updates/renewals, adherence to regulations, and coordination of inter institutional agreements with >25 collaborators).
Associate Professor of Medicine (Endocrinology) and, by courtesy, of Health Research and Policy (Epidemiology) at the Palo Alto Veterans Affairs Health Care System
Current Research and Scholarly InterestsI am a clinical scientist (PhD epidemiology), endocrinologist, and CMO at VAPA Cooperative Studies Program Coordinating Center . My group does pattern and prediction mapping along the life-course of interventions/outcomes and how healthcare system can positively impact health longitudinally. We use novel molecular epi, 'big' data like EHRs with advanced new designs/methods/technologies. These interests cut across multiple complex chronic diseases, aging, & critical lifespan stages.
Mary Leonard, M.D., M.S.C.E., Arline and Pete Harman Professor and Chair, Department of Pediatrics
Arline and Pete Harman Professor and Professor of Medicine (Nephrology) and, by courtesy, of Health Research and Policy (Epidemiology)
Current Research and Scholarly InterestsMy multidisciplinary research program is focused on (1) the detrimental effects of glucocorticoids, sarcopenia and inflammation on bone development in pediatric diseases, (2) the long-term effects of childhood cancer on bone and muscle quality, (3) the assessment of renal osteodystrophy using novel micro-imaging techniques, (4) the effects of vitamin D deficiency on physical function and cardiovascular disease, and (5) the evaluation of biomechanical interventions as anabolic bone therapies.
MD Student with Scholarly Concentration in Clinical Research, expected graduation Spring 2019
Masters Student in Epidemiology and Clinical Research, admitted Autumn 2017
BioBen is a fourth-year medical student completing a dual degree MD/MS in Epidemiology and Clinical Research. His major clinical interests are cardiology and hematology-oncology, while his primary academic interests lie in clinical outcomes research, global health, and medical education. Ben's current research examines how clinicians can better predict post-operative mortality in heart failure patients undergoing non-cardiac surgery. He also works with the Digital Medical Education International Collaborative (Digital MEdIC), a Stanford-led platform building a digital curriculum for medical schools around the world.
MD Student with Scholarly Concentration in Health Services & Policy Research, expected graduation Spring 2019
Ph.D. Student in Epidemiology and Clinical Research with Scholarly Concentration in Health Services & Policy Research, admitted Autumn 2016
BioI am an MD/PhD (Epidemiology) candidate, infectious diseases epidemiologist, and global health policy scientist. My work draws upon diverse quantitative methodologies to inform policy in global infectious diseases.
Professor of Biomedical Data Science and, by courtesy, of Radiology (Molecular Imaging) and of Health Research and Policy (Epidemiology)
Current Research and Scholarly InterestsBiostatistics, clinical trials, statistical evaluation of medical diagnostic tests, radiology, osteoporosis, meta-analysis, medical decisoin making