School of Medicine
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Professor of Pediatrics (Endocrinology) at the Lucile Salter Packard Children's Hospital and at the Stanford University Medical Center
BioIn 2016 I moved to become Professor of Pediatrics and Division Chief of Pediatric Endocrinology at Stanford University. My research interest is to improve care and prevent complications in people with type 1 diabetes (T1D). I was co-author with Dr Peter Chase on the 12th and 13th editions of Understanding Diabetes, or Pink Panther education books. Specifically, my research has extended from epidemiologic studies identifying targets to development of clinical trials to test interventions. My NIDDK sponsored K23 “Cardiovascular Disease in Type 1 Diabetes Mellitus: Young Adults to Adolescents” focused on cardiovascular and kidney complications in young adults with T1D. I continued this work as part of the Coronary Artery Calcification in Type 1 Diabetes (CACTI) Study with Drs. Marian Rewers and Janet Snell-Bergeon and in the pediatric population with Dr. Paul Wadwa and as investigator with the Search for Diabetes in Youth study. I am a past co-Chair for Protocols and Publications with the Type 1 Diabetes Exchange and continue as a Steering Committee member and director of international collaborations which complements my role as Secretary-General for ISPAD. While in Colorado I was local PI on PERL, an RCT to prevent early kidney function decline with Drs Michael Mauer (UMinnesota) and Alessandro Doria (Joslin) as PIs. I am a PI on FL3X, an innovative behavioral intervention for adolescents with T1D with Drs. Elizabeth Mayer-Davis (UNC) and Michael Seid (Cincinnati). As a logical extension of this research to prevent T1D complications, my research has increasingly focused on the development of the artificial pancreas as improved glucose control is the best proven method to prevent T1D complications. In Colorado I was the local PI on 3 UC4 funded artificial pancreas studies and I continue this research at Stanford with Drs Bruce Buckingham and Korey Hood. I work with clinical and engineering collaborators at RPI, JAEB, Sansum/UCSB, Yale, UVa, Cambridge, Boston University, and UC-Boulder on JDRF, NIDDK, and NSF funded studies as listed below. I was co-PI with Dr. Klingensmith on the Barbara Davis Center T32 and K12 training grants in Pediatric Endocrinology. I am Associate Director of the Stanford University Diabetes Research Center with Drs Seung Kim (Director) and Frederic Kraemer https://sdrc.stanford.edu .
Professor of Pediatrics (Hematology/Oncology) and of Medicine
Current Research and Scholarly InterestsRecent clinical studies, by us and others, have demonstrated that T cell based immunotherapy can eradicate cancers resistant to all other available therapies. Our program is focused on using genetically engineered T cells to treat cancer. We link the bench with the bedside, developing novel therapies for early phase testing in clinical trials, will simultaneously conducting intensive studies on clinical samples obtained from patients treated on immunotherapy trials.
Professor (Research) of Microbiology and Immunology
Current Research and Scholarly InterestsI'm interested in immune monitoring of T cell responses to chronic pathogens such as CMV, and the correlation of T cell response signatures with disease protection.
Ravi Majeti MD, PhD
Associate Professor of Medicine (Hematology)
Current Research and Scholarly InterestsThe Majeti lab focuses on the molecular/genomic characterization and therapeutic targeting of leukemia stem cells in human hematologic malignancies, particularly acute myeloid leukemia (AML). Our lab uses experimental hematology methods, stem cell assays, genome editing, and bioinformatics to define and investigate drivers of leukemia stem cell behavior. As part of these studies, we have led the development and application of robust xenotransplantation assays for human hematopoietic cells.
Senior Associate Dean, Faculty Development and Diversity and Professor of Pediatrics (Infectious Diseases)
Current Research and Scholarly InterestsMy research focuses on epidemiologic aspects of viral vaccines and perinatal HIV infection. This includes the molecular epidemiology of factors affecting the immunogenicity of oral polio vaccine (OPV) in developing areas of the world, and now the epidemiology of transmission and circulation of vaccine derived polioviruses in order to assist in global eradication of polio. I also work in development of methods to prevent breastfeeding transmission of HIV in Africa.
Sanjay V. Malhotra, PhD, FRSC
Associate Professor (Research) of Radiation Oncology (Radiation and Cancer Biology) and of Radiology (Molecular Imaging Program at Stanford)
Current Research and Scholarly InterestsMy research interests focus on the design and discovery of synthetic, and natural product inspired small molecules which can be used as probes for developing understanding of biological phenomena, including protein-protein interactions and modulation of signal transduction pathways. My laboratory employs the tools of synthetic medicinal chemistry, molecular modeling and chemical biology for translational research in drug discovery, development, imaging and radiation.
M. Peter Marinkovich, MD
Associate Professor of Dermatology
Current Research and Scholarly InterestsThe Marinkovich lab studies the function of epithelial extracellular matrix molecules, including integrins, collagens and laminins in epithelial development and carcinoma progression. We apply our discoveries in this area towards development of molecular therapies for carcinomas, hair disease and inherited epithelial adhesive disorders.
John D. Mark
Clinical Professor, Pediatrics - Pulmonary Medicine
BioDr. Mark received his medical degree from the University of Kansas and completed his residency in pediatrics at Children’s Mercy Hospital in Kansas City, Missouri. He then completed a fellowship in pediatric pulmonary medicine at the University of Rochester, Rochester, New York. In 1999, Dr. Mark completed the first fellowship in Pediatric Integrative Medicine at the University of Arizona. He practices at Packard Children’s Hospital where he utilizes non-conventional approaches with patients who have chronic illnesses such asthma and cystic fibrosis. He is interested in nutrition and the mind/body approach to healing in an effort to decrease dependence on medication.
Dr. Mark is the Program Director for the Pediatric Pulmonary fellowship program, Associate Director for the Pediatric residency program and the Medical Director for the Coordinating and Optimizing Resources Effectively (CORE) Program at Packard Children’s Hospital, Stanford University. This innovative program assists with care coordination and communication with all health care providers for children with complex medical needs.