School of Medicine
Showing 1-10 of 41 Results
Associate Professor of Materials Science and Engineering and of Photon Science
BioMelosh's research is focused on developing methods to detect and control chemical processes on the nanoscale, to create materials that are responsive to their local environment. The research goal incorporates many of the hallmarks of biological adaptability, based on feedback control between cellular receptors and protein expression. Similar artificial networks may be achieved by fabricating arrays of nanoscale devices that can detect and influence their local surroundings through ionic potential, temperature, mechanical motion, capacitance, or electrochemistry. These devices are particularly suited as smart biomaterials, where multiple surface-cell interactions must be monitored and adjusted simultaneously for optimal cell adhesion and growth. Other interests include precise control over self-assembled materials, and potential methods to monitor the diagnostics of complicated chemical systems, such as the effect of drug treatments within patients.
Molecular materials at interfaces
Directed dynamic self-assembly
Controlling molecular or biomolecular assembly and behavior
Influence of local electronic, optical or thermal stimuli
Denise M. Monack
Professor of Microbiology and Immunology
Current Research and Scholarly InterestsThe primary focus of my research is to understand the genetic and molecular mechanisms of intracellular bacterial pathogenesis. We use several model systems to study complex host-pathogen interactions in the gut and in immune cells such as macrophages and dendritic cells. Ultimately we would like to understand how Salmonella persists within certain hosts for years in the face of a robust immune response.
Assistant Professor of Biology
Current Research and Scholarly InterestsOur research interests are to elucidate the contribution of chromatin to mechanisms that promote genomic integrity.
Professor of Pediatrics (Endocrinology) at the Lucile Salter Packard Children's Hospital and at the Stanford University Medical Center
BioIn 2016 I moved to become Professor of Pediatrics and Division Chief of Pediatric Endocrinology at Stanford University. My research interest is to improve care and prevent complications in people with type 1 diabetes (T1D). I was co-author with Dr Peter Chase on the 12th and 13th editions of Understanding Diabetes, or Pink Panther education books. Specifically, my research has extended from epidemiologic studies identifying targets to development of clinical trials to test interventions. My NIDDK sponsored K23 “Cardiovascular Disease in Type 1 Diabetes Mellitus: Young Adults to Adolescents” focused on cardiovascular and kidney complications in young adults with T1D. I continued this work as part of the Coronary Artery Calcification in Type 1 Diabetes (CACTI) Study with Drs. Marian Rewers and Janet Snell-Bergeon and in the pediatric population with Dr. Paul Wadwa and as investigator with the Search for Diabetes in Youth study. I am a past co-Chair for Protocols and Publications with the Type 1 Diabetes Exchange and continue as a Steering Committee member and director of international collaborations which complements my role as Secretary-General for ISPAD. While in Colorado I was local PI on PERL, an RCT to prevent early kidney function decline with Drs Michael Mauer (UMinnesota) and Alessandro Doria (Joslin) as PIs. I am a PI on FL3X, an innovative behavioral intervention for adolescents with T1D with Drs. Elizabeth Mayer-Davis (UNC) and Michael Seid (Cincinnati). As a logical extension of this research to prevent T1D complications, my research has increasingly focused on the development of the artificial pancreas as improved glucose control is the best proven method to prevent T1D complications. In Colorado I was the local PI on 3 UC4 funded artificial pancreas studies and I continue this research at Stanford with Drs Bruce Buckingham and Korey Hood. I work with clinical and engineering collaborators at RPI, JAEB, Sansum/UCSB, Yale, UVa, Cambridge, Boston University, and UC-Boulder on JDRF, NIDDK, and NSF funded studies as listed below. I was co-PI with Dr. Klingensmith on the Barbara Davis Center T32 and K12 training grants in Pediatric Endocrinology. I am Associate Director of the Stanford University Diabetes Research Center with Drs Seung Kim (Director) and Frederic Kraemer https://sdrc.stanford.edu .
Professor of Pediatrics (Hematology/Oncology) and of Medicine
Current Research and Scholarly InterestsRecent clinical studies, by us and others, have demonstrated unequivocally that T cell based immunotherapy can eradicate cancers resistant to all other available therapies. Our program is focused on using genetically engineered T cells to treat cancer. We link the bench with the bedside, developing novel therapies for early phase testing in clinical trials, as well as conducting intensive studies on clinical samples obtained from patients treated on immunotherapy trials.
Professor (Research) of Microbiology and Immunology
Current Research and Scholarly InterestsI'm interested in immune monitoring of T cell responses to chronic pathogens such as CMV, and the correlation of T cell response signatures with disease protection.
Ravi Majeti MD, PhD
Associate Professor of Medicine (Hematology)
Current Research and Scholarly InterestsThe Majeti lab focuses on the molecular/genomic characterization and therapeutic targeting of leukemia stem cells in human hematologic malignancies, particularly acute myeloid leukemia (AML). Our lab uses experimental hematology methods, stem cell assays, genome editing, and bioinformatics to define and investigate drivers of leukemia stem cell behavior. As part of these studies, we have led the development and application of robust xenotransplantation assays for human hematopoietic cells.
Senior Associate Dean, Faculty Development and Diversity and Professor of Pediatrics (Infectious Diseases)
Current Research and Scholarly InterestsMy research focuses on epidemiologic aspects of viral vaccines and perinatal HIV infection. This includes the molecular epidemiology of factors affecting the immunogenicity of oral polio vaccine (OPV) in developing areas of the world, and now the epidemiology of transmission and circulation of vaccine derived polioviruses in order to assist in global eradication of polio. I also work in development of methods to prevent breastfeeding transmission of HIV in Africa.
Sanjay V. Malhotra, PhD, FRSC
Associate Professor (Research) of Radiation Oncology (Radiation and Cancer Biology) and of Radiology (Molecular Imaging Program at Stanford)
Current Research and Scholarly InterestsMy research interests focus on the design and discovery of synthetic, and natural product inspired small molecules which can be used as probes for developing understanding of biological phenomena, including protein-protein interactions and modulation of signal transduction pathways. My laboratory employs the tools of synthetic medicinal chemistry, molecular modeling and chemical biology for translational research in drug discovery, development, imaging and radiation.