School of Medicine
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Assistant Professor of Cardiothoracic Surgery
Current Research and Scholarly InterestsOur lab aims to understand the biomechanics that govern a wide spectrum of congenital heart defects, and how those biomechanics change with contemporary operative repair strategies. We simulate operations virtually via CFD, and in ex vivo and in vivo animal models, and analyze how the changes we make alter fluid flow, pressure, and stresses throughout the system. We hope that these experiments can impact and optimize existing techniques that translate quickly to the operating room.
Professor of Pediatrics (Endocrinology) and, by courtesy, of Epidemiology and Population Health
BioDr David M. Maahs is Professor of Pediatrics and Division Chief of Pediatric Endocrinology at Stanford University and the Lucile Packard Children’s Hospital. He earned his MD followed by Pediatric Residency at the University of New Mexico. After 3 years on New Mexico’s faculty, Dr. Maahs completed a Pediatric Endocrinology fellowship and a concurrent PhD in Epidemiology at the University of Colorado. He remained on Colorado’s faculty for 10 years, advancing to Professor of Pediatrics before moving to Stanford. Prior to his medical career, Dr. Maahs received a BA and MA in English from the University of Kansas and was inspired to pursue a medical career after serving in the Peace Corps with assignments in Tunisia and the Central African Republic.
Dr. Maahs’ leadership experiences include being a past co-Chair (2013-16) for Protocols and Publications with the Type 1 Diabetes Exchange for which he continues as a Steering Committee member and Director of International Collaborations. This complements his role as Secretary-General for the International Society of Pediatric and Adolescent Diabetes (ISPAD, 2016-20) and Editor-in-Chief for the 2018 ISPAD Clinical Practice Consensus Guidelines. He currently serves on the Professional Practice Committee for the American Diabetes Association (ADA, 2016-18), which writes the annual ADA Standards of Care. Previously, he served on the ADA Scientific Sessions committee representing the Council on Youth. He has also served on national committees for the American Heart Association, the Pediatric Endocrine Society, and multiple journal editorial boards and review committees.
His scholarly interest is improving care and preventing complications in people with type 1 diabetes (T1D). Along with Dr Peter Chase, he is author of the 12th and 13th editions of Understanding Diabetes, or ‘Pink Panther,’ which are the most widely used educational books for children newly diagnosed with T1D, distributed internationally by the Juvenile Diabetes Research Fund (JDRF). More specifically, he has conducted epidemiologic studies that help generate hypotheses for clinical studies, including trials to develop artificial pancreas systems to improve glucose control, lower disease burden, and prevent diabetic complications. He is author or co-author of over 300 research publications. His multi-disciplinary research has been funded by the JDRF, the National Institutes of Diabetes and Digestive and Kidney Diseases (NIDDK), the Helmsley Charitable Trust, and the National Science Foundation (NSF).
Dr Maahs is Associate Director for the recently formed and NIDDK P30 funded Stanford University Diabetes Research Center (https://sdrc.stanford.edu). His collaborations extend to his role as Principal Investigator (PI) or steering committee member for NIH funded multi-center clinical trials including the FLEX, PERL, and ACTION studies as well as multiple Artificial Pancreas clinical trials. Education, mentorship, and training leadership includes being Program Director with Dr. Georgeanna Klingensmith on the Barbara Davis Center T32 and K12 training grants in Pediatric Endocrinology while at the University of Colorado. He is the PI on the Stanford NIH funded K12 "Training Research Leaders in Type 1 Diabetes.'
While in the Peace Corps, David met his wife, Christine Walravens, who is also a Pediatrician at Stanford. They enjoy outdoor activities and traveling with their children, Nicholas (22) and Natalia (16).
Ernest and Amelia Gallo Family Professor and Professor of Pediatrics and of Medicine
Current Research and Scholarly InterestsRecent clinical studies, by us and others, have demonstrated that genetically engineered T cells can eradicate cancers resistant to all other therapies. We are identifying new targets for these therapeutics, exploring pathways of resistance to current cell therapies and creating next generation platforms to overcome therapeutic resistance. We have discovered novel insights into the biology of human T cell exhaustion and developed approaches to prevent and reverse this phenomenon.
Professor (Research) of Microbiology and Immunology
Current Research and Scholarly InterestsI'm interested in immune monitoring of T cell responses to chronic pathogens and cancer, and the correlation of T cell response signatures with disease protection.
Assistant Professor of Neurosurgery
BioDr. Mahaney is a Pediatric Neurosurgeon with clinical interest in Hydrocephalus, Craniovertebral Junction abnormalities, Spasticity, Spinal dysraphism and Myelomeningocele, Central Nervous System tumors, and Pediatric Epilepsy surgery. She completed residency training at the University of Iowa Hospitals and Clinics and subspecialty Pediatric Neurosurgery training at The Hospital for Sick Children in Toronto and the Barrow Neurologic Institute at Phoenix Children's Hospital. She is interested in advancing Neuro-endoscopic techniques in Pediatric Neurosurgical practice. Dr. Mahaney's research focuses on delineating the role of iron in the development of post-hemorrhagic hydrocephalus.
Clinical Professor, Medicine - Primary Care and Population Health
Current Research and Scholarly InterestsStanford Primary Care delivers innovative, high-quality, personalized and holistic care for patients and families throughout their lives. We are leading the shift from a health care system focused on medical care for individual patients toward an integrated health system focused on health and wellness of a population. Stanford Primary Care partners with multiple stakeholders across Stanford Health Care and Stanford University to achieve the quadruple aim.
Ravindra Majeti MD, PhD
RZ Cao Professor
Current Research and Scholarly InterestsThe Majeti lab focuses on the molecular/genomic characterization and therapeutic targeting of leukemia stem cells in human hematologic malignancies, particularly acute myeloid leukemia (AML). Our lab uses experimental hematology methods, stem cell assays, genome editing, and bioinformatics to define and investigate drivers of leukemia stem cell behavior. As part of these studies, we have led the development and application of robust xenotransplantation assays for human hematopoietic cells.
Senior Associate Dean, Faculty Development and Diversity, Taube Professor of Global Health and Infectious Diseases, Professor of Pediatrics (Infectious Diseases) and of Epidemiology and Population Health
Current Research and Scholarly InterestsMy research focuses on epidemiologic aspects of viral vaccines and perinatal HIV infection. This includes the molecular epidemiology of factors affecting the immunogenicity of oral polio vaccine (OPV) in developing areas of the world, and now the epidemiology of transmission and circulation of vaccine derived polioviruses in order to assist in global eradication of polio. I also work in development of methods to prevent breastfeeding transmission of HIV in Africa.
M. Peter Marinkovich, MD
Associate Professor of Dermatology
Current Research and Scholarly InterestsThe Marinkovich lab studies the function of epithelial extracellular matrix molecules, including integrins, collagens and laminins in epithelial development and carcinoma progression. We apply our discoveries in this area towards development of molecular therapies for carcinomas, hair disease and inherited epithelial adhesive disorders.
John D. Mark
Clinical Professor, Pediatrics - Pulmonary Medicine
BioDr. Mark received his medical degree from the University of Kansas and completed his residency in pediatrics at Children’s Mercy Hospital in Kansas City, Missouri. He then completed a fellowship in pediatric pulmonary medicine at the University of Rochester, Rochester, New York. In 1999, Dr. Mark completed the first fellowship in Pediatric Integrative Medicine at the University of Arizona. He practices at Packard Children’s Hospital where he utilizes non-conventional approaches with patients who have chronic illnesses such asthma and cystic fibrosis. He is interested in nutrition and the mind/body approach to healing in an effort to decrease dependence on medication.
Dr. Mark is the Program Director for the Pediatric Pulmonary fellowship program, Associate Director for the Pediatric residency program and the Medical Director for the Coordinating and Optimizing Resources Effectively (CORE) Program at Packard Children’s Hospital, Stanford University. This innovative program assists with care coordination and communication with all health care providers for children with complex medical needs.
Senior Associate Dean for the Social Sciences and the Lewis M. Terman ProfessorOn Leave from 04/01/2021 To 06/30/2021
BioMarkman’s research interests include the relationship between language and thought; early word learning; categorization and induction; theory of mind and pragmatics; implicit theories and conceptual change, and how theory-based explanations can be effective interventions in health domains.
Professor of Pediatrics (Cardiology) and of Bioengineering
Current Research and Scholarly InterestsThe Cardiovascular Biomechanics Computation Lab at Stanford develops novel computational methods for the study of cardiovascular disease progression, surgical methods, and medical devices. We have a particular interest in pediatric cardiology, and use virtual surgery to design novel surgical concepts for children born with heart defects.
Professor of Surgery (Abdominal Transplantation)
Current Research and Scholarly InterestsHost-Pathogen interactions; EBV B cell lymphomas; pathways of immune evasion in the growth and survival of EBV B cell lymphomas; mechanisms of graft rejection and tolerance induction; stem cell and solid organ transplantation.
Instructor, Pediatrics - Stem Cell Transplantation
BioI am a physician scientist at Stanford University/Lucile Packard Children’s Hospital, with a clinical and research focus in stem cell transplantation. Prior training includes earning MD and PhD degrees through the combined program at Saint Louis University School of Medicine, where I investigated the role of the cyclin dependent kinase inhibitor p21 in suppression of inflammatory cytokine production and treating inflammatory diseases. This project led to the publication of two first-author peer-reviewed articles, several middle-author publications, and a significant review article. I subsequently completed Pediatrics residency at the University of California Los Angeles/Mattel Children's Hospital and Pediatric Hematology/Oncology Fellowship at Stanford. Currently I'm an Instructor of Pediatrics in the division of Stem Cell Transplantation and Regenerative Medicine.
My long-term career goal is to develop a research program focusing on immune tolerance in stem cell transplantation and become a leader in the development of improved therapies for preventing or treating graft-versus-host disease. As such, I am excited about my ongoing work in the laboratory of Dr. Robert Negrin, focusing on the expansion and functional enhancement of regulatory T cells and invariant natural killer T cells. This work is currently supported by a St. Baldrick’s Foundation Fellowship, and has previously received funding from the Stanford Child Health Research Institute.