School of Medicine
Showing 41-60 of 74 Results
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Nicholas Melosh
Professor of Materials Science and Engineering
BioThe Melosh group explores how to apply new methods from the semiconductor and self-assembly fields to important problems in biology, materials, and energy. We think about how to rationally design engineered interfaces to enhance communication with biological cells and tissues, or to improve energy conversion and materials synthesis. In particular, we are interested in seamlessly integrating inorganic structures together with biology for improved cell transfection and therapies, and designing new materials, often using diamondoid molecules as building blocks.
My group is very interested in how to design new inorganic structures that will seamless integrate with biological systems to address problems that are not feasible by other means. This involves both fundamental work such as to deeply understand how lipid membranes interact with inorganic surfaces, electrokinetic phenomena in biologically relevant solutions, and applying this knowledge into new device designs. Examples of this include “nanostraw” drug delivery platforms for direct delivery or extraction of material through the cell wall using a biomimetic gap-junction made using nanoscale semiconductor processing techniques. We also engineer materials and structures for neural interfaces and electronics pertinent to highly parallel data acquisition and recording. For instance, we have created inorganic electrodes that mimic the hydrophobic banding of natural transmembrane proteins, allowing them to ‘fuse’ into the cell wall, providing a tight electrical junction for solid-state patch clamping. In addition to significant efforts at engineering surfaces at the molecular level, we also work on ‘bridge’ projects that span between engineering and biological/clinical needs. My long history with nano- and microfabrication techniques and their interactions with biological constructs provide the skills necessary to fabricate and analyze new bio-electronic systems.
Research Interests:
Bio-inorganic Interface
Molecular materials at interfaces
Self-Assembly and Nucleation and Growth -
Fernando S. Mendoza
Associate Dean of Minority Advising and Programs and Professor of Pediatrics (General Pediatrics) at the Lucile Salter Packard Children's Hospital, Emeritus
Current Research and Scholarly InterestsI have two research interests: childhood health disparities and workforce diversity. My research on childhood health disparities centers on Latino and immigrant children with a focus on early childhood health and development. My work in workforce diversity examines the pipeline for diversity in academic pediatrics, with special attention on the pipeline for underrepresent minorities.
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Vinod Menon
Rachael L. and Walter F. Nichols, MD, Professor and Professor, by courtesy, of Education and of Neurology and Neurological Sciences
Current Research and Scholarly InterestsEXPERIMENTAL, CLINICAL AND THEORETICAL SYSTEMS NEUROSCIENCE
Cognitive neuroscience; Systems neuroscience; Cognitive development; Psychiatric neuroscience; Functional brain imaging; Dynamical basis of brain function; Nonlinear dynamics of neural systems. -
Mark Mercola
Professor of Medicine (Cardiovascular) and, by courtesy, of Chemical and Systems Biology
BioDr. Mercola is Professor of Medicine and Professor in the Stanford Cardiovascular Institute. He completed postdoctoral training at the Dana-Farber Cancer Institute and Harvard Medical School, was on the faculty in the Department of Cell Biology at Harvard Medical School for 12 years, and later at the Sanford-Burnham-Prebys Institute and Department of Bioengineering at the University of California, San Diego before relocating to Stanford in 2015.
Prof. Mercola is known for identifying many of the factors that are responsible for inducing and forming the heart, including the discovery that Wnt inhibition is a critical step in cardiogenesis that provided the conceptual basis and reagents for the large-scale production of cardiovascular tissues from pluripotent stem cells. He has collaborated with medicinal chemists, optical engineers and software developers to pioneer the use of patient iPSC-cardiomyocytes for disease modeling, safety pharmacology and drug development. His academic research is focused on developing and using quantitative high throughput assays of patient-specific cardiomyocyte function to discover druggable targets for preserving contractile function in heart failure and promoting regeneration following ischemic injury. He co-established drug screening and assay development at the Conrad Prebys Drug Discovery Center (San Diego), which operated as one of 4 large screening centers of the US National Institutes of Health (NIH) Molecular Libraries screening initiative and continues as one of the largest academic drug screening centers.
Prof. Mercola received an NIH MERIT award for his work on heart formation. He holds numerous patents, including describing the invention of the first engineered dominant negative protein and small molecules for stem cell and cancer applications. He serves on multiple editorial and advisory boards, including Vala Sciences, Regencor, The Ted Rogers Centre for Heart Research and the Human Biomolecular Research Institute. His laboratory is funded by the National Institutes of Health (NIH), California Institute for Regenerative Medicine, Phospholamban Foundation and Fondation Leducq. -
Everett Meyer
Associate Professor of Medicine (Blood and Marrow Transplantation and Cellular Therapy), of Pediatrics (Stem Cell Transplantation) and, by courtesy, of Surgery (Abdominal Transplantation)
Current Research and Scholarly InterestsResearch focus in T cell immunotherapy and T cell immune monitoring using high-throughput sequencing and genomic approaches, with an emphasis on hematopoietic stem cell transplantation, the treatment of graft-versus-host disease and immune tolerance induction.
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Timothy Meyer
Stanford University Professor of Nephrology, Emeritus
Current Research and Scholarly InterestsInadequate removal of uremic solutes contributes to widespread illness in the more than 500,000 Americans maintained on dialysis. But we know remarkably little about these solutes. Dr. Meyer's research efforts are focused on identifying which uremic solutes are toxic, how these solutes are made, and how their production could be decreased or their removal could be increased. We should be able to improve treatment if we knew more about what we are trying to remove.
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Emmanuel Mignot, MD, PhD
Craig Reynolds Professor of Sleep Medicine and Professor, by courtesy, of Genetics and of Neurology and Neurological Sciences
Current Research and Scholarly InterestsThe research focus of the laboratory is the study of sleep and sleep disorders such as narcolepsy and Kleine Levin syndrome. We also study the neurobiological and genetic basis of the EEG and develop new tools to study sleep using nocturnal polysomnography. Approaches mostly involve human genetic studies (GWAS, sequencing), EEG signal analysis (deep learning), and immunology (narcolepsy is an autoimmune disease of the brain). We also work on autoimmune encephalitis.
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Carlos Milla
Professor of Pediatrics (Pulmonary Medicine) and, by courtesy, of Medicine (Pulmonary and Critical Care Medicine)
Current Research and Scholarly InterestsAt Stanford University I developed and currently direct the CF Translational Research Center. The overarching goal of the center is to provide the groundwork to streamline, accelerate, and promote the translation of basic discoveries into effective therapies and interventions to benefit patients affected by cystic fibrosis. My laboratory group currently has three main lines of investigation: respiratory cell biology in CF; remote biochemical monitoring; and lung physiology in young children.
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Alicia Mirza
Clinical Assistant Professor, Medicine - Pulmonary, Allergy & Critical Care Medicine
BioDr. Alicia Mirza is quadruple board-certified in Internal Medicine, Pediatrics, Pulmonary Medicine, and Critical Care Medicine. She is now an Assistant Professor in the Division of Pulmonary, Allergy, and Critical Care Medicine (PACCM) at Stanford, where she serves as Associate Director of the Adult Cystic Fibrosis (CF) Program.
She has expertise across a breadth of pulmonary and intensive care domains, with her clinical and research interests centering on CF and bronchiectasis. She is a CF Foundation (CFF) Program for Adult Care Excellence grant awardee. She has worked on quality improvement projects in adult CF care, including initiatives in advanced care planning, pediatric to adult transitions, primary care utilization, and remote monitoring. She is involved in clinical trials as well as registry-based research in both CF and non-CF bronchiectasis.
Nationally, Dr. Mirza was elected to the CHEST Bronchiectasis Network, where she collaborates with experts across the country to expand education in bronchiectasis through podcasts, training modules, and lectures. An active educator, Dr. Mirza teaches Stanford medical students, residents, and fellows. She is engaged both locally and internationally through conference presentations at CHEST, California Thoracic Society, and the North American CF Conference.
She also serves as Co-director of Wellbeing for Stanford PACCM, where she is committed to advancing faculty wellness and fostering a culture of professional fulfillment. In both her clinical and academic work, she emphasizes a holistic approach to supporting patients and colleagues alike, with attention to the whole person and the systems that sustain their health and wellbeing. -
Maneesh Kumar Misra
Clinical Associate Professor, Pathology
Current Research and Scholarly InterestsMy research goal is to utilize the cutting edge of stat of art histocompatibility testing to better understand the humoral and cellular responses in clinical transplantation, and to translate this knowledge into improved treatment, and transplant outcome.
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Daria Mochly-Rosen
George D. Smith Professor of Translational Medicine
Current Research and Scholarly InterestsTwo areas: 1. Using rationally-designed peptide inhibitors to study protein-protein interactions in cell signaling. Focus: protein kinase C in heart and large GTPases regulating mitochondrial dynamics in neurodegdenration. 2. Using small molecules (identified in a high throughput screens and synthetic chemistry) as activators and inhibitors of aldehyde dehydrogenases, a family of detoxifying enzymes, and glucose-6-phoshate dehydrogenase, in normal cells and in models of human diseases.
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Everett J. Moding, MD, PhD
Assistant Professor of Radiation Oncology (Radiation Therapy)
Current Research and Scholarly InterestsMy laboratory performs translational research using analysis of human samples to identify critical mediators of treatment resistance that can be validated in preclinical models and targeted to enhance the efficacy of cancer therapy.
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Matteo Amitaba Mole'
Assistant Professor of Obstetrics and Gynecology (Reproductive, Perinatal & Stem Cell Biology Research)
Current Research and Scholarly InterestsWe study how the human embryo implants inside the maternal uterine tissue to establish a healthy pregnancy and the underlying maternal-embryo communication.
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Denise M. Monack
Martha Meier Weiland Professor in the School of Medicine
Current Research and Scholarly InterestsThe primary focus of my research is to understand the genetic and molecular mechanisms of intracellular bacterial pathogenesis. We use several model systems to study complex host-pathogen interactions in the gut and in immune cells such as macrophages and dendritic cells. Ultimately we would like to understand how Salmonella persists within certain hosts for years in the face of a robust immune response.
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Michelle Monje
Milan Gambhir Professor of Pediatric Neuro-Oncology and Professor, by courtesy, of Neurosurgery, of Pediatrics, of Pathology and of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsThe Monje Lab studies the molecular and cellular mechanisms of postnatal neurodevelopment. This includes microenvironmental influences on neural precursor cell fate choice in normal neurodevelopment and in disease states.
