School of Medicine


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  • William Nelson

    William Nelson

    Rudy J. and Daphne Donohue Munzer Professor in the School of Medicine, Emeritus

    Current Research and Scholarly InterestsOur research objectives are to understand the cellular mechanisms involved in the development and maintenance of epithelial cell polarity. Polarized epithelial cells play fundamental roles in the ontogeny and function of a variety of tissues and organs.

  • Roeland Nusse

    Roeland Nusse

    Virginia and Daniel K. Ludwig Professor of Cancer Research

    Current Research and Scholarly InterestsOur laboratory studies Wnt signaling in development and disease. We found recently that Wnt proteins are unusual growth factors, because they are lipid-modified. We discovered that Wnt proteins promote the proliferation of stem cells of various origins. Current work is directed at understanding the function of the lipid on the Wnt, using Wnt proteins as factors the expand stem cells and on understanding Wnt signaling during repair and regeneration after tissue injury.