School of Medicine

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  Suzanne Pfeffer

  Emma Pfeiffer Merner Professor of Medical Sciences
  

  Current Research and Scholarly InterestsThe major focus of our research is to understand the molecular basis of inherited Parkinson's Disease (PD). We focus on the LRRK2 kinase that is inappropriately activated in PD and how it phosphorylates Rab GTPases, blocking the formation of primary cilia in specific regions of the brain. The absence of primary cilia renders cells unable to carry out Hedgehog signaling that is critical for neuroprotective pathways that sustain dopamine neurons.

  • Contact Info

    • Beckman Center Room B413
    • 279 Campus Drive
    • Stanford, California 94305-5307

    Mail Code: 5307

    • (650) 725-5130 (office)

    pfeffer@stanford.edu

  • Web page:

    http://pfeffer.stanford.edu/