School of Medicine
Showing 1-9 of 9 Results
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Michael Edward Palmer
Affiliate, Genetics
Visiting Scholar, GeneticsBioI'm visiting the Marc Feldman Lab while writing my book, "Clade Thinking: The Macroevolution of Recursive Clades and the Evolution of Evolvability". The motivating question of the book is, "Can macroevolution be reduced to merely the repeated iteration of microevolution?" (Short answer: no, you would be missing some fundamental evolutionary dynamics.)
For the past three years, I've taught a short course called "The Evolution of Evolvability" on the same topic as my book.
I'm also doing some machine learning (ML) applied to genomics with the Fraser Lab, related to the evolution of cis-regulatory elements (CREs), which have been involved in a lot of recent/rapid evolution in mammals. We are doing what we call "in silico genome transplants": placing DNA variants from one species into the (ML-modeled) cellular environment of another species (or cell type, or individual with some pathology, etc.). We analyze variation in gene expression to detect various modes of selection on CREs.
I got my B.S. in Physics at Yale, and my Ph.D. in Computer Science at the California Institute of Technology. In my career, I've gone back and forth between academia (computational biology) and the tech industry in Silicon Valley. -
John R. Pringle
Professor of Genetics, Emeritus
Current Research and Scholarly InterestsMuch of our research exploits the power of yeast as an experimentally tractable model eukaryote to investigate fundamental problems in cell and developmental biology such as the mechanisms of cell polarization and cytokinesis. In another project, we are developing the small sea anemone Aiptasia as a model system for study of the molecular and cellular biology of dinoflagellate-cnidarian symbiosis, which is critical for the survival of most corals but still very poorly understood.
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Jonathan Pritchard
Bing Professor of Population Studies, Professor of Genetics and Biology
Current Research and Scholarly InterestsWe are interested in a broad range of problems at the interface of genomics and evolutionary biology. One current focus of the lab is in understanding how genetic variation impacts gene regulation and complex traits. We also have long-term interests in using genetic data to learn about population structure, history and adaptation, especially in humans.
FOR UP-TO-DATE DETAILS ON MY LAB AND RESEARCH, PLEASE SEE: http://pritchardlab.stanford.edu
