School of Medicine
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Allyson Rosen, Ph.D., ABPP-CN
Clinical Professor (Affiliated), Psych/Public Mental Health & Population Sciences
Staff, Psychiatry and Behavioral Sciences
Translational cognitive neuroscience of aging and dementia. Neuroethics.
Dr. Rosen is board certified in clinical neuropsychology with a geriatric focus. She completed college at Brown University, a clinical psychology Ph.D. from Case Western Reserve University, clinical neuropsychology internship at the Long Island Jewish Hospital in New York, and clinical neuropsychology postdoctoral fellowship at the Medical College of Wisconsin. Dr. Rosen completed specialty research fellowship training at the National Institute on Aging (Intramural Research Training Award) and Stanford (NRSA F32, K01) in functional imaging and noninvasive brain stimulation with support from NIA.
CLINICAL AND RESEARCH ACTIVITIES
Dr. Rosen is Director of Dementia Education at the Mental Illness Research Education and Clinical Center at the Palo Alto VAHCS. She is also a neuropsychologist and part of the consensus clinical group and education core at the Stanford’s Alzheimer’s Disease Research Center (NIA). Dr. Rosen’s funded research has focused on applying cognitive neuroscience of aging to improve clinical practice in older adults by using cognitive measures, brain imaging, and noninvasive brain stimulation such as TMS. Studies include using fMRI as an outcome measure for cognitive training, studying how to improve the accuracy of transcranial magnetic stimulation targeting with and without image guidance, and using structural MRI to avoid postoperative cognitive decline and improve outcome from carotid vascular procedures. She has a longstanding commitment to neuroethics and leads a feature in the Journal of Alzheimer Disease that focuses on ethical issues in new and emerging AD applications.
ETHICS EDITOR, JOURNAL OF ALZHEIMER'S DISEASE
MIRECC DEMENTIA EDUCATION
Craig S. Rosen, Ph.D.
Professor of Psychiatry and Behavioral Sciences (Public Mental Health and Population Sciences)
Current Research and Scholarly InterestsMy research aims at improving processes and outcomes of mental health care for veterans other people suffering from post-traumatic stress and other mental disorders.
My primary focus is improving access to evidence-based treatments PTSD and other psychiatric disorders. My second emphasis is using telemedicine technologies to expand access to effective care. My third interest is measurement-based care, using ongoing data on patient progress to inform patients' and clinicians' decisions.
Associate Professor of Medicine (Pulmonary and Critical Care Medicine), Emeritus
Current Research and Scholarly InterestsOur laboratory examines apoptotic and cell signaling pathways in cancer and lung disease. We are studying signaling pathways that regulate oxidative stress responses and cancer cell growth. Part of these studies focus on analysis of non-canonical transcription regulatory functions of the TERC and Tert components of telomerase in lung disease and cancer.
Michael J Rosen, MD, MSCI
Stanford University Endowed Professor for Pediatric IBD and Celiac Disease
BioI am a pediatric gastroenterologist and physician scientist, who has been devoted to inflammatory bowel disease (IBD) research since beginning medical training over 20 years ago. I am also Director of the Stanford Center for Pediatric IBD and Celiac Disease. I have expertise crossing mucosal immunology and epithelial biology, formal training and experience in clinical and translational investigation with human biospecimens, and direct insight regarding the important clinical challenges caring for children with complicated IBD. My translational research program focuses on how the immune system regulates epithelial function in chronic intestinal inflammation as it relates to IBD. My clinical research program has focused on optimization of anti-TNF therapy in pediatric IBD, and in particular acute severe ulcerative colitis (ASUC). My laboratory has demonstrated a protective role for IL33, a cytokine that induces type 2 cytokines from T cells an innate lymphoid cells (ILCs), in acute oxazolone colitis through preservation of epithelial goblet cells and barrier function. In line with this finding, we have also shown in a large prospective patient cohort that mucosal expression of type 2 and type 17 immune response genes distinguishes ulcerative colitis (UC) from colon-only Crohn’s disease, and that type 2 gene expression is associated with superior clinical outcome in pediatric UC. We have now developed an organoid-immune cell in vitro culture system to demonstrate the ILC2-dependent mechanism through which IL33 induces goblet cell differentiation in the intestinal epithelium. I led the multicenter study Anti-TNF for Refractory Colitis in Hospitalized Children (ARCH) Study, which aims to establish determinants of anti-TNF response in pediatric ASUC and currently Co-Chair the Crohn's & Colitis Foundations Cohort for Pediatric Translational and Clinical Research in IBD (CAPTURE IBD) and PRO-KIIDS Pediatric IBD clinical research network.