School of Medicine
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Nazish Sayed MD, PhD
Assistant Professor (Research) of Surgery (Vascular Surgery) and at the Stanford Cardiovascular Institute
Current Research and Scholarly InterestsThe Sayed Laboratory is focused on the development of novel technologies that drive innovation in regenerative medicine, disease modeling, and drug testing in vascular biology. The lab conducts translational research in vascular biology and aims to understand the role of the vasculature in the development of cardiac diseases, including those due to inherited genetic variants or environmental insults such as type 2 diabetes or hypertension. The lab employs the human induced pluripotent stem cell (iPSC) technology to generate patient-specific vascular cells (endothelial and vascular smooth muscle cells) as an alternative to animal models providing a human tissue surrogate for research that is scalable and sustainable. By employing this unique platform, the lab also investigates the role of chemotherapeutic agents (anti-cancer drugs) on the vasculature. Dr. Sayed’s lab has also established an endothelial regeneration program, where they leverage the innate immune system to regenerate endothelial cells from human fibroblasts.
Work from the lab has led to seminal discoveries in the areas of 1) Nitric oxide (NO) biology, (2) vascular biology, (3) stem cell biology, (4) cardiovascular disease modeling (5) cardio-oncology. -
Jordan R. Stern, MD
Clinical Associate Professor, Surgery - Vascular Surgery
BioDr. Stern is a board-certified, fellowship-trained specialist in vascular surgery in the Stanford Vascular and Endovascular Care program. He is a Clinical Associate Professor in the Department of Surgery at Stanford University School of Medicine.
Dr. Stern’s clinical and academic interests focus on the treatment of aortic disease. He is a leader in the development of novel treatment strategies for aortic pathology and specializes in minimally invasive, endovascular repair of complex aneurysms and aortic dissection.
For each patient, he develops a personalized treatment plan. The goal is the best possible vascular health and quality of life for every individual in his care.
Patients praise Dr. Stern’s knowledge and attention to detail. They also appreciate his kindness and compassion, his approachability, and the effort he makes to thoroughly answer all questions from patients and their families.
In addition to providing expert patient care, he is the principal investigator on several clinical trials. He is also involved in many additional research endeavors, examining contemporary practice patterns and outcomes from endovascular and open surgical procedures.
He has published the results of his research in numerous journal articles. They have appeared in the Journal of Vascular Surgery, Journal of the American College of Surgery, and many other peer-reviewed journals. The majority of his publications have focused on aortic disease.
He is an editorial board member of the journal Annals of Vascular Surgery and previously was an assistant editor of the Journal of Endovascular Therapy. He also has co-authored chapters in textbooks such as Novel and Evolving Aortic Endovascular Devices and the Atlas of Vascular and Endovascular Techniques.
Dr. Stern has presented his research discoveries to his peers at international, national, and regional meetings. He is a fellow of the Society for Vascular Surgery. He is a member of the Vascular and Endovascular Surgery Society (VESS), where he also serves as inaugural chair of the VESS Research Consortium as well as on the Program Committee. He is a fellow of the American College of Surgeons and a member of the Society for Clinical Vascular Surgery and Western Vascular Society.
