School of Medicine


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  • Vincent Michael Alford

    Vincent Michael Alford

    Postdoctoral Research Fellow, Stem Cell Biology and Regenerative Medicine

    Current Research and Scholarly InterestsMy interest in science and research was fostered at a young age after losing a family member to colorectal cancer. At that young age, it was made apparent to me that cancer remains poorly understood which is reflected in the total lack of target-specific treatment regiments available to this patient population. This disparity in patient care is what inspired me to pursue a Ph.D in Molecular and Cellular Pharmacology at Stony Brook University (SBU). During my time at SBU, my dissertation research focused on the development of a standard approach for rational drug design against the functional activity of individual matrix metalloproteinases (MMPs). Results from this work led to the successful development of the first small molecule inhibitor specifically targeting the hemopexin domain of MMP-9. Additionally, I was also given the opportunity to assist in the development of a cell based High-Throughput Screen assay for the identification of small molecules with activity against cancer cell invasion.

    After obtaining my Ph.D, I pursued a postdoctoral scholar position at Stanford University within the Institute of Stem Cell Biology and Regenerative Medicine. Currently, my projects have slowly become broader and more focused around protein chemistry. More specifically, my research interest lies in identifying protein targets or cell populations responsible for chronic illnesses such as Triple Negative Breast Cancer and Alzheimer’s disease. After identifying the target, my passion lies in understanding the biological function of said target in various biological signaling cascades and cell niche population maintenance. Another area I specialize in is assigning function to the various domains of individual proteins and prioritizing drug development against the most promising targets. Upon identification of the target and validation of the domains responsible for protein activity- it becomes my mission to develop specific inhibitors against them. To this end, I use techniques such as protein mutagenesis, expression, and purification systems in addition to x-ray crystallography and chemical-protein structure activity relationships to understand, rationally design, and optimize these small molecule inhibitors for potential use in clinical trials.

  • Chiara Anselmi

    Chiara Anselmi

    Postdoctoral Research Fellow, Stem Cell Biology and Regenerative Medicine

    BioMy expertise is in the areas of regeneration, evolution, the nervous system and cell biology. I use a marine colonial tunicate, Botryllus schlosseri, characterized by having robust regenerative capabilities and an assayable and frequent (weekly) CNS (Central nervous system) tissue regeneration and loss throughout adult life. I believe that comparative studies on a simple chordate can help us elucidate the principal mechanisms that are the foundation of regeneration and aging.
    I hypothesize that age-associated changes in molecular regulators of neural stem cells contribute to decreased stem cell function (i.e., regenerative capacity) and assayable indicators (i.e., phenotypes) of aging in B. schlosseri. Moreover, these drivers of age-associated stem cell decline can be identified and, when manipulated, will prolong neural stem cell function and potentially delay the onset of phenotypes of central nervous system aging. I use a multidisciplinary methodology that integrates advanced single cell RNAseq, live imaging, and multi-parameter flow cytometric isolation of cellular populations, cell sorting, transplantation assays to elucidate the cellular and genetic changes associated with the weekly neuronal degeneration process in young and old colonies.

  • Jane Antony

    Jane Antony

    Postdoctoral Research Fellow, Stem Cell Biology and Regenerative Medicine

    Current Research and Scholarly InterestsAlthough varying degrees of progress has been made to treat the heterogenous subtypes of breast cancers, metastasis and recurrence remains a major cause of breast cancer-related deaths. My research focuses on drivers of tumor growth and testing new targets for these breast cancers to prevent metastasis and recurrence; specifically, profiling and validating genes enriched in the self-renewing tumorigenic compartment.

  • Joydeep Bhadury

    Joydeep Bhadury

    Postdoctoral Research Fellow, Stem Cell Biology and Regenerative Medicine

    Current Research and Scholarly InterestsMy long-term goal is to generate whole human organs in large research animals, which will be universally immune compatible and ready for human transplantation.

  • Sabra Djomehri

    Sabra Djomehri

    Postdoctoral Research Fellow, Stem Cell Biology and Regenerative Medicine

    Current Research and Scholarly InterestsMy passion is translating bioinformatics integrative workflows and engineering platforms from multi-omics data to better discovery of new therapies. Experienced in statistical analyses and mathematical modeling early in my career and currently working on single-cell sequencing analyses (scRNA-seq), genomics (WES), and epigenomics (targeted chromatin ligation), data integration methods, and algorithm development.