School of Medicine
Showing 1-10 of 115 Results
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Ragini Adams
Clinical Assistant Professor, Pediatrics - Hematology & Oncology
Current Research and Scholarly InterestsCirculating tumor DNA (ctDNA) is DNA that is released by tumor cells into the blood of the host; it is a fraction of all the cell free DNA (cfDNA) that is present. Because ctDNA contains the mutations of the original tumor, it is detectable using next generation sequencing and is an accurate surrogate measure of tumor burden. Therefore, ctDNA is an emerging biomarker in Hodgkin Lymphoma (HL) that is specific, quantifiable, and can be measured by noninvasive means. Using ctDNA to explore the genetic landscape of pediatric HL and monitor the response of these patients to therapy has never been done before and is my current focus of study.
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Catherine Aftandilian
Clinical Associate Professor, Pediatrics - Hematology & Oncology
Current Research and Scholarly InterestsI am interested in the prevention and management of infectious complication in pediatric oncology patients. I am also interested in developing a protocol for the management of low risk patients with fever and neutropenia.
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Vali Barsan
Instructor, Pediatrics - Hematology & Oncology
Current Research and Scholarly InterestsAdoptive T cell immunotherapy entails engineering immune cells to recognize cancer-specific antigens and target them for destruction. Barriers to efficacy can arise from both tumor antigen related as well as T cell related features. I am interested developing noninvasive molecular tools that enable us to understanding these relationships to improve the clinical application and development of cellular immunotherapeutics.