School of Medicine


Showing 1-36 of 36 Results

  • Justin P. Annes M.D., Ph.D.

    Justin P. Annes M.D., Ph.D.

    Associate Professor of Medicine (Endocrinology)
    On Partial Leave from 05/01/2024 To 02/28/2025

    Current Research and Scholarly InterestsThe ANNES LABORATORY of Molecular Endocrinology: Leveraging Chemical Biology to Treat Endocrine Disorders

    DIABETES
    The prevalence of diabetes is increasing at a staggering rate. By the year 2050 an astounding 25% of Americans will be diabetic. The goal of my research is to uncover therapeutic strategies to stymie the ensuing diabetes epidemic. To achieve this goal we have developed a variety of innovate experimental approaches to uncover novel approaches to curing diabetes.

    (1) Beta-Cell Regeneration: Diabetes results from either an absolute or relative deficiency in insulin production. Our therapeutic strategy is to stimulate the regeneration of insulin-producing beta-cells to enhance an individual’s insulin secretion capacity. We have developed a unique high-throughput chemical screening platform which we use to identify small molecules that promote beta-cell growth. This work has led to the identification of key molecular pathways (therapeutic targets) and candidate drugs that promote the growth and regeneration of islet beta-cells. Our goal is to utilize these discoveries to treat and prevent diabetes.

    (2) The Metabolic Syndrome: A major cause of the diabetes epidemic is the rise in obesity which leads to a cluster of diabetes- and cardiovascular disease-related metabolic abnormalities that shorten life expectancy. These physiologic aberrations are collectively termed the Metabolic Syndrome (MS). My laboratory has developed an original in vivo screening platform t to identify novel hormones that influence the behaviors (excess caloric consumption, deficient exercise and disrupted sleep-wake cycles) and the metabolic abnormalities caused by obesity. We aim to manipulate these hormone levels to prevent the development and detrimental consequences of the MS.

    HEREDIATY PARAGAGLIOMA SYNDROME
    The Hereditary Paraganglioma Syndrome (hPGL) is a rare genetic cancer syndrome that is most commonly caused by a defect in mitochondrial metabolism. Our goal is to understand how altered cellular metabolism leads to the development of cancer. Although hPGL is uncommon, it serves as an excellent model for the abnormal metabolic behavior displayed by nearly all cancers. Our goal is to develop novel therapeutic strategies that target the abnormal behavior of cancer cells. In the laboratory we have developed hPGL mouse models and use high throughput chemical screening to identify the therapeutic susceptibilities that result from the abnormal metabolic behavior of cancer cells.

    As a physician scientist trained in clinical genetics I have developed expertise in hereditary endocrine disorders and devoted my efforts to treating families affected by the hPGL syndrome. By leveraging our laboratory expertise in the hPGL syndrome, our care for individuals who have inherited the hPGL syndrome is at the forefront of medicine. Our goal is to translate our laboratory discoveries to the treatment of affected families.

  • Danit Ariel

    Danit Ariel

    Clinical Associate Professor, Medicine - Endocrinology, Gerontology, & Metabolism

    BioDanit Ariel, MD MS, is board certified in Endocrinology. Dr. Ariel graduated from UC Davis School of Medicine. She then completed a residency in Internal Medicine at Stanford and a fellowship and post-doctorate in Endocrinology and Metabolism at Stanford before joining the faculty at Stanford.

    Dr. Ariel practices general endocrinology, with a special interest in menopause, LGBTQ+ health, transgender medicine, reproductive endocrinology and thyroid disorders amongst others.

    She believes in practicing compassionate care: in listening to her patients’ concerns, respecting their values, communicating well, and providing an evidence-based approach to help guide individualized treatment plans. She is deeply committed to utilizing her expertise in the field of endocrinology to optimize her patients’ health and well-being.

    Dr. Ariel is passionate about medical education and teaching, and serves on the teaching faculty in the Stanford University School of Medicine. She completed an honors certificate in medical education from Stanford. She is the Founding Director of the Student Guidance Program for medical students. Finally, within the division of Endocrinology, she is the Director of Faculty Wellness.

    Appointments with with Dr. Ariel are available in the Hoover Pavilion on 211 Quarry Road as part of the Stanford Health Care Endocrinology Clinic and the Stanford Health Care LGBTQ+ Health Program.

  • Marina Basina

    Marina Basina

    Clinical Professor, Medicine - Endocrinology, Gerontology, & Metabolism

    Current Research and Scholarly InterestsDiabetes type I and type II, insulin pump therapy, glucose sensor technology, insulin resistance, PCOS, thyroid disorders

  • Julia J. Chang, MD

    Julia J. Chang, MD

    Clinical Assistant Professor, Medicine - Endocrinology, Gerontology, & Metabolism
    Clinical Assistant Professor (By courtesy), Neurosurgery

    BioDr. Chang is a board-certified endocrinologist. She is a Clinical Assistant Professor in Stanford Medicine’s Division of Endocrinology and, by courtesy, the Department of Neurosurgery. She specializes in pituitary disorders, including prolactinomas, Cushing disease, acromegaly, non-functional pituitary masses and cysts, and hypopituitarism, as well as transgender health and gender-affirming hormone care.

    For each patient, she develops a comprehensive, compassionate care plan personalized to individual needs. Her goal is always the best possible health and quality of life for every patient in her care.

    Dr. Chang actively leads several pituitary and transgender care research, quality improvement, and education initiatives. She teaches Stanford trainees and serves as the associate program director for the Stanford Endocrinology Fellowship. She has published widely and presented her research at international conferences and is a member of the Endocrine Society, Pituitary Society, and the World Professional Association of Transgender Health. She is a native English speaker, and she also understands Korean.

    In-person and telehealth appointments with Dr. Chang are available at Stanford Endocrinology Clinic at Hoover Pavilion, Pituitary Center at Stanford Neurosciences Health Center, and the Stanford Brain Tumor Center at Stanford Cancer Center. She is also a part of the LGBTQ+ Health Program.

  • Julie Chen

    Julie Chen

    Clinical Associate Professor, Medicine - Endocrinology, Gerontology, & Metabolism

    BioJulie Chen, MD, is a board-certified endocrinologist and clinical assistant professor in the division of endocrinology at Stanford University. Dr. Chen diagnoses and treats a wide range of conditions with a focus on endocrine tumors that affect the thyroid, parathyroid, adrenal, and pituitary glands. She also works closely with cancer specialists to treat the endocrine side effects associated with immunotherapy. Dr. Chen recognizes that patients are more than their disease. She views her relationship with each patient as a partnership and develops a personalized care plan for each one. Dr. Chen is committed to helping patients achieve the best possible outcomes through comprehensive treatment.

    Dr. Chen is also passionate about medical education and mentoring. She currently serves as the Program Director for the Endocrinology Fellowship Program at Stanford University. She has given numerous lectures to medical students, residents, and fellows.

  • Katrin Chua

    Katrin Chua

    Professor of Medicine (Endocrinology, Gerontology and Metabolism)

    Current Research and Scholarly InterestsOur lab is interested in understanding molecular processes that underlie aging and age-associated pathologies in mammals. We focus on a family of genes, the SIRTs, which regulate stress resistance and lifespan in lower organisms such as yeast, worms, and flies. In mammals, we recently uncovered a number of ways in which SIRT factors may contribute to cellular and organismal aging by regulating resistance to various forms of stress. We have now begun to characterize the molecular mechanisms by which these SIRT factors function. In particular, we are interested in how SIRT factors regulate chromatin, the molecular structure in which the DNA of mammalian genomes is packaged, and how such functions may link genome maintenance to stress resistance and aging.

  • Lawrence Crapo

    Lawrence Crapo

    Professor of Medicine (Endocrinology, Gerontology and Metabolism) at the Santa Clara Valley Medical Center, Emeritus

    Current Research and Scholarly InterestsInvestigation of the epidemiology of diabetic ketoacidosis (DKA) at a public hospital. All cases of DKA at SCVMC occurring over the past 5 years have been identified. Of the 480 cases of DKA, about 1/3 are in Type II diabetics, and 2/3 in Type I diabetics. We are exploring the causes of DKA in the two groups.

  • Dimpi Desai

    Dimpi Desai

    Clinical Assistant Professor, Medicine - Endocrinology, Gerontology, & Metabolism

    BioDr. Dimpi Desai, MD is a Clinical Assistant Professor at Stanford University. She did her residency in Internal Medicine from Jacobi Medical Center/Albert Einstein College of Medicine in New York and completed her fellowship in Endocrinology at the University of Pennsylvania.
    Her main clinical focus includes diabetes and obesity and preventing their long-term complications. She strongly believes in patient education and involving them in the medical decision-making process. In addition to being a clinician, she is committed to and involved in the medical education of trainees at all levels including medical students, residents and fellows. She is double board certified in internal medicine and endocrinology.

  • Kaniksha Desai

    Kaniksha Desai

    Clinical Associate Professor, Medicine - Endocrinology, Gerontology, & Metabolism

    BioDr. Kaniksha Desai is a board-certified endocrinologist and clinical associate professor at Stanford University. She completed her endocrinology fellowship at the Mayo Clinic, with an emphasis on the management of patients with thyroid cancer. Dr. Desai’s clinical practice focuses on the management of patients with thyroid nodules and thyroid cancer. She also maintains board certification in neck ultrasonography.

  • Chrysoula Dosiou

    Chrysoula Dosiou

    Clinical Professor, Medicine - Endocrinology, Gerontology, & Metabolism

    Current Research and Scholarly InterestsI am highly interested in the interactions between the endocrine and immune systems in women. Current clinical research interests lie in the field of autoimmune thyroid disease, especially thyroid autoimmunity in pregnancy.

  • David Feldman

    David Feldman

    Professor of Medicine (Endocrinology, Gerontology and Metabolism), Emeritus

    Current Research and Scholarly InterestsStudies of the role of the vitamin D receptor in the action of 1,25-dihydroxyvitamin D, the active vitamin D hormone. Current efforts are evaluating the vitamin D receptor in breast and prostate cancer, osteoporosis and rickets.

  • Neil Gesundheit

    Neil Gesundheit

    George DeForest Barnett Founders Professor of Medicine and Professor (Teaching) of Medicine (Endocrinology)

    Current Research and Scholarly InterestsOur medical education research group is developing and validating the best educational practices to train competent, compassionate, and ethical physicians and physician-scientists. We are studying the use of standardized patients and other modalities to improve clinical skill training and reasoning. We are interested in applying the rigor of clinical investigation to education research.

    My areas of clinical interest in endocrinology include disorders of the pituitary, thyroid, and gonad.

  • Andrew R. Hoffman

    Andrew R. Hoffman

    Professor of Medicine (Endocrinology), Emeritus

    Current Research and Scholarly InterestsMechanism of genomic imprinting of insulin like growth factor-2 and other genes.Long range chromatin interactions Role of histone modifications and DNA methylation in gene expression.

  • David Karpf

    David Karpf

    Adjunct Clinical Professor, Medicine - Endocrinology, Gerontology, & Metabolism

    BioMy specialty within Endocrinology is Metabolic Bone Disease, including both osteoporosis and hypoparathyroidism, as well as other conditions including hyper- and hyo-calcemia, hypercalciuria, Paget's Disease, Osteogenesis Imperfecta, hypophosphatasia, and other metabolic bone diseases, as well as diabetes and thyroid diseases.

  • Seung K. Kim  M.D., Ph.D.

    Seung K. Kim M.D., Ph.D.

    KM Mulberry Professor, Professor of Developmental Biology, of Medicine (Endocrinology) and, by courtesy, of Pediatrics (Endocrinology)

    Current Research and Scholarly InterestsWe study the development of pancreatic islet cells using molecular, embryologic and genetic methods in several model systems, including mice, pigs, human pancreas, embryonic stem cells, and Drosophila. Our work suggests that critical factors required for islet development are also needed to maintain essential functions of the mature islet. These approaches have informed efforts to generate replacement islets from renewable sources for diabetes.

  • Sun Kim, M.D. M.S.

    Sun Kim, M.D. M.S.

    Associate Professor of Medicine (Endocrinology)

    Current Research and Scholarly InterestsWe are interested in studying the pathophysiological processes that contribute to glucose intolerance and type 2 diabetes mellitus. My current research focuses on characterizing pancreatic beta-cell function in populations with significant insulin resistance and vulnerability to developing diabetes: individuals with schizophrenia, morbid obesity, and history of gestational diabetes.

  • Fredric Kraemer

    Fredric Kraemer

    Gerald M. Reaven, MD, Professor of Endocrinology, Emeritus

    Current Research and Scholarly InterestsOur research interests are in the general area of cellular lipid and lipoprotein metabolism. The work is aimed primarily at understanding the mechanisms regulating cholesterol and triglyceride accumulation in cells. We utilize a variety of techniques from cell biology, biochemistry, and molecular biology.

  • Rayhan A. Lal, MD

    Rayhan A. Lal, MD

    Assistant Professor of Medicine (Endocrinology) and of Pediatrics (Endocrinology)

    BioI grew up in the east bay area and have had type 1 diabetes for 30+ years. I studied electrical engineering and computer science at U.C. Berkeley (Go Bears!) with the hope of applying my knowledge to diabetes technology. The significance of clinical practice became clear to me after my siblings also developed diabetes. I am devoting my life to advancing the care of diabetes in people of all ages.

  • Jennifer Lee

    Jennifer Lee

    Professor of Medicine (Endocrinology) and, by courtesy, of Epidemiology and Population Health

    Current Research and Scholarly InterestsI am a healthcare lead and physician scientist for innovation, R&D, and advanced analytics, and oversee these aspects at VA Palo Alto/VHA, within Stanford-VA relationship. The VA has the US's largest health care system and longest running EHR. I prioritize enabling multiple partners (industry, government, academia, foundations), to innovate/R&D in the VA health care system. We prioritize mentoring students from various Schools to become future leaders in R&D, innovation, and healthcare.

  • Robert Marcus

    Robert Marcus

    Professor (Clinical) of Medicine (Endocrinology, Gerontology and Metabolism), Emeritus

    Current Research and Scholarly InterestsI have been retired since 2008 and no longer conduct research

  • Tracey McLaughlin

    Tracey McLaughlin

    Professor of Medicine (Endocrinology)

    Current Research and Scholarly InterestsDr. McLaughlin conducts clinical research related to obesity, insulin resistance, diabetes, and cardiovascular disease (CVD). Current studies include: 1) the impact of macronutrient composition on metabolism, DM2 and CVD; 2) comparison of different weight loss diets on metabolism and CVD risk reduction ; 3) role of adipocytes and adipose tissue immune cells in modulating insulin resistance; 4) use of continuous glucose monitoring and multi-omics to define metabolic phenotype and precision diets

  • Susan Meyhak Seav

    Susan Meyhak Seav

    Clinical Assistant Professor, Medicine - Endocrinology, Gerontology, & Metabolism
    Clinical Assistant Professor (By courtesy), Neurosurgery

    BioDr. Seav is a Clinical Assistant Professor in the Division of Endocrinology at Stanford and, by courtesy, the Department of Neurosurgery. She graduated from Harvard University with an honors degree in molecular and cellular biology before completing her medical education and residency at the University of California, San Diego. She then completed her endocrinology fellowship at Stanford University.

    She has a special interest in disorders that involve the pituitary and adrenal glands such as Cushing syndrome, acromegaly, hyperaldosteronism, and pheochromocytoma. Dr. Seav is determined to provide her patients with personalized, evidence-based medicine that will allow them to live their best lives. In addition to caring for patients, Dr. Seav is also passionate about medical education and devoted a chief medical residency year teaching medical students, interns, and residents.

    In-person and telehealth appointments with Dr. Seav are available at Stanford Endocrinology Clinic at Hoover Pavilion, Pituitary Center at Stanford Neurosciences Health Center, and the Stanford Brain Tumor Center at Stanford Cancer Center.

  • Deborah Sellmeyer

    Deborah Sellmeyer

    Clinical Professor, Medicine - Endocrinology, Gerontology, & Metabolism

    BioDr. Sellmeyer is an internationally recognized expert in Metabolic Bone Disease. She is a renowned clinician who joined the Stanford faculty in 2018 as a Professor of Medicine. She has been recognized for her clinical excellence with induction into the Miller Coulson Academy of Clinical Excellence while she was at Johns Hopkins. In addition to her clinical expertise, Dr. Sellmeyer maintains a research program that centers on the effect of nutrition and environmental factors on skeletal metabolism which she has investigated through both smaller CRC-based trials and large multi-center trials. Studies she has conducted have investigated the role of dietary sodium chloride, source of dietary protein (animal, vegetable, dairy, soy), role of dietary potassium and alkaline potassium salts, targeted thoracic exercises on kyphosis, whether structured exercise can prevent bone loss in premenopausal women treated for breast cancer, and studies validating nutritional assessment questionnaires. Her expertise as a clinical researcher has enabled development of a multi-disciplinary translational research team including basic scientists in the orthopedic department, junior faculty members with K grant funding, and basic scientists in the endocrine division to develop translational projects studying the effects of osteoporosis medications on basic elements of skeletal biology utilizing bone biopsies from treated individuals as well as clinical trials of novel therapies for rare bone disorders. Dr. Sellmeyer also is a esteemed educator, having received multiple teaching awards.

  • Aimee D. Shu

    Aimee D. Shu

    Clinical Associate Professor, Medicine - Endocrinology, Gerontology, & Metabolism

    BioI am an endocrinologist with particular interests in reproductive and bone health.

    I enjoy treating patients with menstrual disorders, menopause, fractures, osteoporosis, parathyroid imbalance, and calcium imbalance.

    As a certified menopause practitioner (North American Menopause Society), I help women fine-tune their health at the mid-life transition. Some women transition through menopause with ease, while others experience challenging symptoms like hot flashes, slowed metabolism, and mood changes. This transition period provides a good opportunity to create a "game plan" for preserving future health. It also marks the beginning of natural bone loss, leaving one more susceptible to fragility fractures.

    I provide individualized treatment plans for bone health to men and women of all ages, including for those with specific challenges such as chronic steroid use. As a certified clinical densitometrist (International Society for Clinical Densitometry), I personally review all my patients' bone density scan images. Thus, please bring any non-Stanford bone density scan images to your appointment with me.

    Appointments with me are available on Stanford's main campus (300 Pastuer Drive) and at the Stanford Medicine Outpatient Center (450 Broadway, Redwood City).

  • Marilyn Tan

    Marilyn Tan

    Clinical Associate Professor, Medicine - Endocrinology, Gerontology, & Metabolism

    Current Research and Scholarly InterestsType 2 diabetes, obesity, insulin resistance

  • Molly Tanenbaum

    Molly Tanenbaum

    Clinical Assistant Professor, Medicine - Endocrinology, Gerontology, & Metabolism
    Clinical Assistant Professor (By courtesy), Pediatrics - Endocrinology and Diabetes

    BioDr. Tanenbaum is a clinical researcher committed to improving health and quality of life outcomes for people with diabetes. Dr. Tanenbaum’s research focuses on two main areas: 1) understanding and optimizing the role of technology (e.g. mobile technology/mHealth, diabetes devices, closed-loop systems), and the feedback technology provides, to improve diabetes management; and 2) understanding the emotional experience of living with diabetes. Her recent work has focused on developing a telehealth-based behavioral intervention for adults with type 1 diabetes to support adoption and sustained use of continuous glucose monitoring technology. She has expertise in using qualitative and mixed methods to take a human centered approach to understanding the context of living with and managing a chronic condition. Dr. Tanenbaum also has an interest in compassion-based approaches to addressing diabetes distress. As a licensed clinical psychologist, Dr. Tanenbaum provides consultation and behavioral medicine interventions with people living with diabetes.

  • Joy Wu

    Joy Wu

    Gerald M. Reaven, MD Professor of Endocrinology

    Current Research and Scholarly InterestsMy laboratory focuses on the pathways that regulate the differentiation of mesenchymal stem cells into the osteoblast and adipocyte lineages. We are also studying the role of osteoblasts in the hematopoietic and cancer niches in the bone marrow microenvironment.