School of Medicine
Showing 701-750 of 826 Results
Clinical Associate Professor, Pediatrics - Critical Care
Current Research and Scholarly InterestsMy research interests focus on using dissemination and implementation science tools to study and enhance care provided to patients in the pediatric ICU. I have a background in human factors research and in implementation science and am also interested in clinical effectiveness and outcomes in the PICU.
Instructor, Pediatrics - Pulmonary Medicine
BioDr. Steffes, a Wisconsin native, completed medical school and pediatric residency at the Medical College of Wisconsin. She then moved to the Bay Area and completed her clinical fellowship in pediatric pulmonary medicine at Stanford University in 2020. Additionally, Dr. Steffes received further post-doctoral training in the laboratories of Dr. Maya Kumar and Dr. David Cornfield, studying the cellular and molecular mechanism driving pulmonary vascular disease. In addition to her role as an Instructor in Pediatrics in the division of Pulmonary Medicine, Dr. Steffes is also completing an advanced clinical fellowship in Pulmonary Hypertension at Lucile Packard Children’s Hospital Stanford. Her clinical work consists of caring for patients with pediatric pulmonary and pulmonary vascular diseases such as pulmonary hypertension, bronchopulmonary dysplasia, interstitial lung disease, respiratory failure, chronic cough and asthma. Her research is focused on the vascular changes seen in pulmonary hypertension, more specifically understanding the cellular characteristics of occlusive neointimal lesions, the abnormal cells that block pulmonary blood flow in pulmonary hypertension. In her most recent work, Dr. Steffes identified a subset of healthy vascular smooth muscle cells that are the cell of origin for the pathologic neointimal cells and a specific signaling pathway, that when blocked, inhibits the formation of neointimal lesions.
Dr. Steffes is currently employing advanced single cell sequencing technologies to further understand neointimal cells with the ultimate goal identifying new therapies for pulmonary hypertension, a fatal disease with no known cure.
Lawrence Steinman, MD
George A. Zimmermann Professor and Professor of Pediatrics
Current Research and Scholarly InterestsOur laboratory is dedicated to understanding the pathogenesis of autoimmune diseases, particularly multiple sclerosis. We have developed several new therapies for autoimmunity, including some in Phase 2 clinical trials, as well as one approved drug, natalizumab. We have developed microarray technology for detecting autoantibodies to myelin proteins and lipids. We employ a diverse range of molecular and celluar approaches to trying to understand multiple sclerosis.
Professor of Genetics
Current Research and Scholarly InterestsWe apply diverse genomic approaches to understand how genetic variation affects health and disease by: 1) functional and mechanistic analyses of gene regulation, 2) studies of meiotic recombination and inheritance, 3) analyses of genetic and environmental interactions, and 4) characterization of diseases in human cells and model organisms. We integrate wet lab and computational genomic, transcriptomic, proteomic and metabolic approaches, and develop technologies to enable personalized medicine.
David A. Stevens
Professor of Medicine, Emeritus
Current Research and Scholarly InterestsImmunology and chemotherapy of human fungal diseases, particularly coccidioidomycosis (Valley Fever) in California and aspergillosis, and the parasitic disease, trypanosomiasis.
Professor of Pediatrics (Genetics)
Current Research and Scholarly InterestsMy research focuses on disorders of the RAS/MAPK pathway (eg. NF1, Noonan, CFC, and Costello syndrome). I am working on understanding the impact of RAS signaling on the musculoskeletal system. I use genomic approaches to identify somatic events and modifiers in the RASopathies. I am also involved in identifying outcome measures for use in clinical trials for the associated orthopedic manifestations. Other areas of research involve vascular anomalies, Prader-Willi syndrome, and hypophosphatasia.
David K. Stevenson, M.D.
Harold K. Faber Professor of Pediatrics, Senior Associate Dean, Maternal and Child Health and Professor, by courtesy, of Obstetrics and Gynecology
Current Research and Scholarly InterestsOur research is focused on the study of the ontogeny and control of heme catabolism and bilirubin production in the developing neonate. A better understanding of the role of increased bilirubin production in neonatal jaundice and the prevention of hemolytic jaundice has remained an overall objective of our program. We are also study the causes of preterm birth and ways to prevent it.
Assistant Professor of Radiology (Cancer Early Detection-Canary Center)
Current Research and Scholarly InterestsStoyanova lab develops new early cancer detection methods and therapeutic strategies for late stage cancers. The current research focus is on protein-based biomarkers for early cancer detection as well as development of new small molecule inhibitors and antibody-based therapies for prostate and other epithelial cancers. The ultimate goals of the laboratory are to improve the early diagnosis and prognosis of clinically significant cancers and guide the development of novel and effective therapeutic strategies for metastatic prostate and other epithelial cancers.
Aaron F. Straight
Professor of Biochemistry and, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly InterestsWe study the biology of chromosomes. Our research is focused on understanding how chromosomal domains are specialized for unique functions in chromosome segregation, cell division and cell differentiation. We are particularly interested in the genetic and epigenetic processes that govern vertebrate centromere function, in the organization of the genome in the eukaryotic nucleus and in the roles of RNAs in the regulation of chromosome structure.
Clinical Professor, Medicine - Gastroenterology & Hepatology
BioDr. Sarah Streett is a Clinical Professor of Medicine, the Director of Inflammatory Bowel Disease Education at Stanford, and she is passionate about taking care of people with IBD. She is a national expert in treating complex IBD and initiated a multi-disciplinary approach to care with colorectal surgery, pediatrics, and nutrition. In 2018 she received the Champion of Hope Award from the Crohn’s and Colitis Foundation and serves on their National Scientific Advisory Committee. Her interests focus on fertility and pregnancy in people with IBD, developing precision approaches to IBD therapy, and the role that the microbiome and diet play in its pathogenesis. She is a primary investigator of the Stanford IBD Registry and has research projects focused on optimizing clinical outcomes in IBD, the role of the microbiota and diet in IBD and pregnancy, and applying new technologies to individualizing therapy for IBD. She is also the primary investigator on multiple industry-sponsored IBD trials.
Teaching is a top priority for Dr. Streett who feels that mentoring fellows in the development of their careers is a privilege. She has held many national leadership roles in the American Gastroenterological Association, where she has been Chair of the Practice Management and Economics Committee, and currently serves on the Government Affairs Committee. She also an appointed member of the Gastrointestinal Drug Advisory Committee at the FDA. She has represented the interests of gastroenterologists and their patients on Capitol Hill numerous times. Dr. Streett believes strongly in a collaborative approach to give patients personalized care based on the latest therapies for the treatment of IBD and is committed to mentoring the next generation of experts in the field.
Associate Professor of Emergency Medicine
Current Research and Scholarly InterestsDr. Strehlow's research is focused on global health and global emergency care. Working with in-country partners, he aims to identify the epidemiology of emergencies in developing countries and leverage the growth of emergency care systems in innovative ways to improve the overall health of the population. Specific examples include improving patient flow between the community and different level facilities and using emergency call center infrastructure to combat gender based violence.
Clinical Professor, Pediatrics - Critical Care
Current Research and Scholarly InterestsMy clinical pharmacology research is focused on investigating the impact of dynamic organ function on drug disposition and designing dosing strategies based on mathematical models that account for these changes in order to optimize safe medication administration in critically ill children.
Research through the REVIVE Initiative for Resuscitation Excellence investigates the quality of resuscitation during cardiopulmonary arrest. Areas of focus include early identification during the no-flow state prior to CPR initiation and quality of CPR simulation education.
Leslee L.Subak, MD
Katharine Dexter McCormick and Stanley McCormick Memorial Professor and Professor, by courtesy, of Urology
Current Research and Scholarly InterestsMy research focuses on the association of weight and urinary incontinence (UI) in women and clinical trials to test strategies to improve outcomes in women’s genitourinary health. We have shown the independent association of weight and UI and the efficacy of weight loss to treat women with UI. I also conduct studies of epidemiology, economics and cost-effectiveness, and novel interventions for UI, sexual dysfunction, vaginal atrophy, pelvic organ prolapse and menopause symptoms.
Avram Goldstein Professor in the School of Medicine and Professor, by courtesy, of Neurology and of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsInformation transfer at synapses mediates information processing in brain, and is impaired in many brain diseases. Thomas Südhof is interested in how synapses are formed, how presynaptic terminals release neurotransmitters at synapses, and how synapses become dysfunctional in diseases such as autism or Alzheimer's disease. To address these questions, Südhof's laboratory employs approaches ranging from biophysical studies to the electrophysiological and behavioral analyses of mutant mice.
Associate Professor of Anesthesiology, Perioperative and Pain Medicine
BioDr. Pervez Sultan is an Associate Professor of Obstetric Anesthesiology, at Stanford University School of Medicine and also holds an Honorary Faculty position as Associate Professor at University College London. His research interests include defining, characterizing and measuring postpartum recovery.
Pervez is an Arline and Pete Harman Endowed Faculty Scholar of the Stanford Maternal and Child Health Research Institute at Stanford University.
He is an elected member of the Association of University Anesthesiologists and currently serves on the Annual Meeting and Live Events and Curriculum Steering Committees of the Society for Obstetric Anesthesia and Perinatology in addition to the American Society of Anesthesiologists' Subcommittee for Obstetric Anesthesia and the International Anesthesia Research Society. He is a former recipient of the UK National Institute of Academic Anesthesia Research Award.
Researchgate profile: https://www.researchgate.net/profile/Pervez_Sultan2
Google Scholar profile: https://scholar.google.com/citations?user=Z2ftv_IAAAAJ&hl=en
Associate Professor of Linguistics
BioI am an Associate Professor in the Department of Linguistics at Stanford University. I conduct research examining the representations and mechanisms listeners use to understand spoken language, and how linguistic and social factors affect speech perception and word recognition. My current research centers around two main themes: (1) Investigating the effects social information cued by different voices have on memory, and the way social biases result in misremembering, and (2) Using foundational psycholinguistic methodologies to understand how speakers and speaker groups who are new to a community (e.g., the case of Syrian refugees in Germany) accommodate to cultural norms within their native languages.
Vivien Kon-Ea Sun
Clinical Assistant Professor, Pediatrics
BioVivien Sun is a pediatric hospitalist and Clinical Assistant Professor within Stanford’s Division of Pediatric Hospital Medicine. She practices at Stanford Healthcare-Valleycare and California Pacific Medical Center. Vivien’s interests include medical education, professional development, and caring for the underserved.
Vivien graduated from Harvard University with a BA in Chemistry with a language citation in Mandarin. She went on to receive an MPhil in Public Health from Cambridge University and an MD from the University of California, San Francisco. She completed her pediatrics residency at UCSF with the Pediatric Leadership for the Underserved (PLUS) program. Upon completion of residency, she served as Chief Resident of pediatrics at UCSF-Mission Bay.
Yang Sun, MD, PhD
Associate Professor of Ophthalmology
Current Research and Scholarly InterestsWe are interested in the role of inositol phosphatases in eye development and disease, using both animal models and human disease tissue. We are a translational laboratory seeking to understand the basic function of proteins as well as developing therapeutic strategies for clinical trials.
Professor of Urology, Emeritus
Current Research and Scholarly InterestsWe focus on understanding the molecular mechanism of transcription factors that govern the transformation of normal cells to a neoplastic state. We are especially interested in nuclear hormone action and its interactions with other signaling pathways in tumor development and progression.
Professor of Pediatrics at the Lucile Salter Packard Children's Hospital, Emeritus
Current Research and Scholarly InterestsMy primary interests are in the area of neonatal nutrition and developmental gastroenterology. The use of parenteral nutrition in very low birth weight infants, and the introduction of early enteral feeding to stimulate gastrointestinal maturation are my specific areas of investigative endeavors.
Katrin J Svensson
Assistant Professor of Pathology
Current Research and Scholarly InterestsMolecular metabolism
Cell biology and function
James H. Clark Professor in the School of Engineering and Professor of Chemical Engineering and of BioengineeringOn Leave from 10/01/2022 To 06/30/2023
Current Research and Scholarly InterestsProgram Overview
The world we enjoy, including the oxygen we breathe, has been beneficially created by biological systems. Consequently, we believe that innovative biotechnologies can also serve to help correct a natural world that non-natural technologies have pushed out of balance. We must work together to provide a sustainable world system capable of equitably improving the lives of over 10 billion people.
Toward that objective, our program focuses on human health as well as planet health. To address particularly difficult challenges, we seek to synergistically combine: 1) the design and evolution of complex protein-based nanoparticles and enzymatic systems with 2) innovative, uniquely capable cell-free production technologies.
To advance human health we focus on: a) achieving the 120 year-old dream of producing “magic bullets”; smart nanoparticles that deliver therapeutics or genetic therapies only to specific cells in our bodies; b) precisely designing and efficiently producing vaccines that mimic viruses to stimulate safe and protective immune responses; and c) providing a rapid point-of-care liquid biopsy that will count and harvest circulating tumor cells.
To address planet health we are pursuing biotechnologies to: a) inexpensively use atmospheric CO2 to produce commodity biochemicals as the basis for a new carbon negative chemical industry, and b) mitigate the intermittency challenges of photovoltaic and wind produced electricity by producing hydrogen either from biomass sugars or directly from sunlight.
More than 25 years ago, Professor Swartz began his pioneering work to develop cell-free biotechnologies. The new ability to precisely focus biological systems toward efficiently addressing new, “non-natural” objectives has proven tremendously useful as we seek to address the crucial and very difficult challenges listed above. Another critical feature of the program is the courage (or naivete) to approach important objectives that require the development and integration of several necessary-but- not-sufficient technology advances.
Ali Bin Syed
Clinical Assistant Professor, Radiology - Pediatric Radiology
BioDr. Syed is a member of the divisions of Pediatric Radiology and Body MRI and serves as the Director of MRI for Stanford Medicine Children's Health. His clinical interests include MR imaging of pediatric and adult hepatobiliary disorders, inflammatory bowel disease, gynecologic pathology, and congenital heart disease. He is also an active researcher, collaborating with fellow engineers and scientists at Stanford to translate technical innovations in MRI into improved patient care. His recent work focuses on translation of machine learning techniques for rapid, robust MRI in children and adults.
Karl G. Sylvester
Professor of Surgery (Pediatric Surgery)On Partial Leave from 09/01/2022 To 02/28/2023
Current Research and Scholarly InterestsScholarly interests include investigation of molecular markers of human disease that provide diagnostic function, serve as targets for possible therapeutic manipulation, or provide insight into mechanisms of human disease. Specific diseases of interest include common conditions of pregnancy, gut microbial ecology and Necrotizing Enterocolitis (NEC).
Daniel Sze, MD, PhD
Professor of Radiology (Interventional Radiology)On Leave from 11/23/2022 To 12/22/2022
Current Research and Scholarly InterestsTransarterial administration of chemotherapeutics, radioactive microspheres, and biologics for the treatment of unresectable tumors; management of portal hypertension and complications of cirrhosis (TIPS); treatment of complications of organ transplantation; Venous and pulmonary arterial thrombolysis and reconstruction; Stent and Stent-graft treatment of peripheral vascular diseases, aneurysms, aortic dissections
Professor of Developmental Biology
Current Research and Scholarly InterestsWe use genetic and cellular approaches to investigate the molecular basis of glial development and myelination in the zebrafish.
Jean Y. Tang MD PhD
Professor of Dermatology
Current Research and Scholarly InterestsMy research focuses on 2 main areas:
1. Skin cancer:
- New therapeutics to treat and prevent non-melanoma skin cancer, especially by targeting the Hedgehog signaling pathway for BCC tumors
- Genomic analysis of drug-resistant cancers
- Identifying risk factors for skin cancer in the Women's Health Initiative
2. Epidermolysis Bullosa: gene therapy and protein therapy to replace defective/absent Collagen 7 in children and adults with Recessive Dystrophic EB
Professor of Neurosurgery
BioDr. Peter Tass investigates and develops neuromodulation techniques for understanding and treating neurologic conditions such as Parkinson’s disease, epilepsy, dysfunction following stroke and tinnitus. He creates invasive and non-invasive therapeutic procedures by means of comprehensive computational neuroscience studies and advanced data analysis techniques. The computational neuroscience studies guide experiments that use clinical electrophysiology measures, such as high density EEG recordings and MRI imaging, and various outcome measures. He has pioneered a neuromodulation approach based on thorough computational modelling that employs dynamic self-organization, plasticity and other neuromodulation principles to produce sustained effects after stimulation. To investigate stimulation effects and disease-related brain activity, he focuses on the development of stimulation methods that cause a sustained neural desynchronization by an unlearning of abnormal synaptic interactions. He also performs and contributes to pre-clinical and clinical research in related areas.
Joyce Teng, MD, PhD
Professor of Dermatology and, by courtesy, of Pediatrics
BioJoyce Teng, MD, PhD is a professor in dermatology at Stanford University. She is affiliated with multiple hospitals in the area, including Lucile Salter Packard Children's Hospital (LPCH) at Stanford and Stanford Hospital and Clinics (SHC). She received her medical degree from Vanderbilt University School of Medicine and has been in practice for more than 12 years. She is one of the 6 pediatric dermatologists practicing at LPCH and one of 72 at SHC who specialize in Dermatology. She sees patients with rare genetic disorders, birthmarks, vascular anomalies and a variety of inflammatory skin diseases. She is also an experienced pediatric dermatological surgeon. Her research interests are drug discovery and novel therapy for skin disorders.
Associate Professor of Radiology (Pediatric Radiology)
Current Research and Scholarly InterestsOver the past decade there has been tremendous advances in the field of Interventional Oncology with the clinical utilization of multiple new innovative locoregional therapies (i.e. chemoembolization, percutaneous ablation).
Looking forward, our ability to super-selectively deliver new therapies directly to target organs. These therapies include nanoparticles, stem cells and gene therapy and will open new pathways into the emerging field of Interventional Regenerative Medicine.
Assistant Professor of Neurosurgery
Current Research and Scholarly InterestsThe long-term goal of my research is the repair of damaged corticospinal circuitry. Therapeutic regeneration strategies will be informed by an understanding both of corticospinal motor neuron (CSMN) development and of events occurring in CSMN in the setting of spinal cord injury. MicroRNAs are small, non-coding RNAs that regulate the expression of “suites” of genes. The work in my lab seeks to identify microRNA controls over CSMN development and over the CSMN response to spinal cord injury.
Clinical Professor, Psychiatry and Behavioral Sciences - Child & Adolescent Psychiatry and Child Development
Current Research and Scholarly InterestsPediatric Acute-Onset Neuropsychiatric Disorder
Reena Thomas, MD PhD
Clinical Associate Professor, Neurology & Neurological Sciences
Clinical Associate Professor (By courtesy), Neurosurgery
Current Research and Scholarly Interests-Neuro Oncology Immunotherapy
Professor of Biomedical Data Science and of Statistics
Current Research and Scholarly InterestsMy research is in applied statistics and biostatistics. I specialize in computer-intensive methods for regression and classification, bootstrap, cross-validation and statistical inference, and signal and image analysis for medical diagnosis.
Professor of Pediatrics (Cardiology)
Current Research and Scholarly InterestsAssessment of vascular health in children by non-invasive modalities
Exercise interventions in children with congenital and acquired heart disease
Use of telehealth to deliver interventions to children with congenital and acquired heart disease
Quality Improvement in Pediatric Echocardiography
Echocardiography and outcomes in congenital heart disease
Professor of Genetics, of Biology and, by courtesy, of Chemistry
Current Research and Scholarly InterestsWe develop chemogenetic and optogenetic technologies for probing and manipulating protein networks, cellular RNA, and the function of mitochondria and the mammalian brain. Our technologies draw from enzyme engineering, directed evolution, chemical biology, organic synthesis, high-resolution microscopy, genetics, and computational analysis.
Dunlevie Family Professor
BioFlorencia Torche is a social scientist with expertise in social demography and social stratification. Professor Torche’s scholarship examines inequality dynamics including intergenerational mobility, disparities in educational attainment, family dynamics, and assortative mating, among others. Her research also examines the influence of early-life exposures –starting before birth– on iindividual wellbeing and inequality. She was elected to the National Academy of Sciences and the American Academy of Arts and Sciences in 2020, and to the Sociological Research Association in 2013.
Torche has led many large data collection projects, including the first national survey on social mobility in Chile and Mexico. She has served as deputy editor of the American Sociological Review (2020-2022 and 2015-2018), Consulting Editor of the American Journal of Sociology, and Editorial Board of the Journal of Health and Social Behavior, Social Forces, Sociology of Education, and Sociological Theory among others. She has served on the Board of Overseers of the General Social Survey.
Professor Torche holds a BA from the Catholic University of Chile and an MA and PhD in Sociology from Columbia University.
Professor of Medicine (Gastroenterology and Hepatology)
Current Research and Scholarly InterestsOur laboratory has been focusing on the mechanism of liver fibrosis and the role of hepatocyte cell death in fibrogenic injury. We have demonstrated the intricate link between hepatocyte apoptosis, generation of apoptotic bodies and their efferocytosis by stellate cells triggering fibrogenic activation. Key to this was the activation of the NADPH oxidase NOX2 and production of reactive oxidative species inducing stellate cell transdifferentiation and collagen I transcription. We have expanded our work focusing on the role of non-phagocytic NOX4 in dysregulating insulin responses and precipitating ER and mitochondrial stress signaling in non-alcoholic steatohepatitis. We are particularly interested in clinical conditions that are linked to accelerated fibrosis such as during aging and T2DM. Our other major focus is on alcoholic hepatitis, and defining novel therapeutic targets based on sterile inflammatory pathways. Our ultimate goal is translation and developing new treatment approaches that reverse fibrosis and improve patient outcomes.