School of Medicine
Showing 51-100 of 121 Results
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Prasanna Jagannathan
Associate Professor of Medicine (Infectious Diseases) and of Microbiology and Immunology
Current Research and Scholarly InterestsWe study innate immunity and immune regulation of Plasmodium Falciparum malaria in children and pregnant women. Our work focuses on understanding how malaria shapes the immune state in individuals following repeated exposure. We are also testing novel interventions to enhance protective immunity against malaria in children via large, randomized controlled trials. Our work in malaria has been based in Eastern Uganda, where malaria transmission is among the highest in the world.
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Samantha M Kerath
Director of Finance and Administration, Microbiology and Immunology
Current Role at StanfordDirector of Finance & Administration
Microbiology & Immunology and Baxter Lab -
Karla Kirkegaard
Violetta L. Horton Professor and Professor of Microbiology and Immunology
Current Research and Scholarly InterestsThe biochemistry of RNA-dependent RNA polymerase function, the cell biology of the membrane rearrangements induced by positive-strand RNA virus infection of human cells, and the genetics of RNA viruses, which, with their high error rates, live at the brink of error catastrophe, are investigated in the Kirkegaard laboratory.
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Holden Maecker
Professor (Research) of Microbiology and Immunology
On Partial Leave from 09/15/2024 To 08/31/2025Current Research and Scholarly InterestsI'm interested in immune monitoring of T cell responses to chronic pathogens and cancer, and the correlation of T cell response signatures with disease protection.
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David McIlwain
Casual - Non-Exempt, Microbiology and Immunology - Baxter Labs
BioDr. McIlwain studies host-response to infectious disease using high dimensional single-cell and spatial proteomics tools. He trained for his Ph.D. at the University of Toronto exploring mouse biology using reverse genetics with renowned immunologist Dr. Tak W. Mak. His doctoral work yielded insights into alternative mRNA splicing and an important discovery about iRhom2 as a new factor controlling the production of inflammatory mediator TNF. As a post-doctoral fellow, Dr. McIlwain investigated host response to viral infection in animal models at the University of Dusseldorf in Germany before moving to Stanford University where along with Dr. Garry Nolan, he leads a team executing research contracted by the FDA’s medical countermeasures initiative to study emerging pathogens. This work includes mass cytometry (CyTOF) and spatial proteomic (CODEX) single-cell analysis of human and animal model influenza, Ebola, zika, and SARS-CoVs infections.
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Edward Mocarski
Professor of Microbiology and Immunology, Emeritus
Current Research and Scholarly InterestsMy research interests focused on the biology and pathogenesis of cytomegalovirus (CMV), an opportunistic pathogen that causes significant disease worldwide, reporting discoveries in areas of CMV gene regulation, DNA replication and packaging, maturation, impact on the host cell, disease pathogenesis, latency and reactivation, host cell death signaling and chemokine system. In the last 20 years of my academic career, we studied viral cell death suppressors and discovered ZBP1-RIPK3 necroptosis.
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Denise M. Monack
Martha Meier Weiland Professor in the School of Medicine
Current Research and Scholarly InterestsThe primary focus of my research is to understand the genetic and molecular mechanisms of intracellular bacterial pathogenesis. We use several model systems to study complex host-pathogen interactions in the gut and in immune cells such as macrophages and dendritic cells. Ultimately we would like to understand how Salmonella persists within certain hosts for years in the face of a robust immune response.
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Elena Monti
Postdoctoral Scholar, Microbiology and Immunology
BioMy research during my PhD focused on the human neuromuscular system adaptations in response to overloading (training), unloading, aging and disease (specifically, cancer cachexia).
To date, during my postdoc, I am working on the effects of the enzyme 15-PGDH on the neuromuscular system health/connection in young and aged animals. -
Antonio J. Pagán
Assistant Professor of Microbiology and Immunology
Current Research and Scholarly InterestsThe Pagán lab is interested in the regulation of immunity and pathogenesis in tuberculosis (TB). TB is characterized by the formation of multicellular aggregates of immune cells called granulomas. We leverage the powerful genetics and imaging capabilities of genetically diverse fish models of TB, which capture key features of human TB granulomas, to address fundamental questions in mycobacterial pathogenesis and granuloma immunobiology.
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Peter Parham
Professor of Structural Biology and, by courtesy, of Microbiology and Immunology
Current Research and Scholarly InterestsThe Parham laboratory investigates the biology, genetics, and evolution of MHC class I molecules and NK cell receptors.
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Trung Hoang Minh Pham
Assistant Professor of Pediatrics (Infectious Diseases) and of Microbiology and Immunology
Current Research and Scholarly InterestsUncovering mechanisms of tissue immunity and immunophysiology during persistent infection
The immune system safeguards the health of complex organisms by rapidly eliminating invading pathogens, curbing infection-induced tissue disruptions, and maintaining tissue homeostasis. Many bacterial pathogens evade host antimicrobial mechanisms and persist in infected tissues at low levels for long periods of time even in the presence of innate and adaptive immune resistance. During persistent infection, the immune system simultaneously orchestrates antimicrobial responses to contain the pathogen, repairs damaged tissue, regulates nutrient resources, and maintains other tissue physiological functions to ensure host survival. Failure of any of these tasks leads to uncontrolled infection, devastating disease, and even death. The goals of our research are to understand:
1)What are the innate and adaptive immune cellular mechanisms that contain pathogens during persistent infection?
2)How are tissue physiological functions, such as tissue repair and nutrient regulation, maintained during persistent infection?
3)How do pathogens survive innate and adaptive antimicrobial mechanisms in infected tissues?
4)How does persistent infection impact host immunity to secondary infections of a similar or different pathogen?
Through investigating these fundamental questions, we may be able to decode the underlying cellular and molecular mechanisms that can be harnessed to eradicate infections, promote tissue resilience, and restore health after an infectious insult. We employ animal infection models and bring together immunology, tissue biology, microbiology, and genetics to uncover the mechanisms of tissue immunity and immunophysiology during persistent infection from the molecular to organismal level.
Current areas of research:
•Development, maintenance, and plasticity of macrophage functional diversity in infected tissue
•Tissue repair and nutrient regulation during persistent infection
•Cellular dynamics and bacterial persistence in lymphoid organs -
Charles G. Prober, MD
Professor of Pediatrics (Infectious Diseases) and, by courtesy, of Microbiology and Immunology
Current Research and Scholarly InterestsMy research interest is in the epidemiology, pathophysiology, prevention, and treatment of infections in children. Much of this research has focused on viral infections, especially those caused by herpes simplex virus (HSV). I have conducted a number of studies concerned with the epidemiology of HSV-2 infections in pregnant women, their partners, and neonates.
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David A. Relman
Thomas C. and Joan M. Merigan Professor and Professor of Microbiology and Immunology
Current Research and Scholarly InterestsMy investigative program focuses on human-microbe interactions and human microbial ecology, and primarily concerns the ecology of human indigenous microbial communities; a secondary interest concerns the classification of humans with systemic infectious diseases, based on features of genome-wide gene transcript abundance patterns and pther aspects of the host response.
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Peter Sarnow
Burt and Marion Avery Professor of Immunology
Current Research and Scholarly InterestsOur laboratory studies virus-host interactions with an emphasis microRNA-mediated gene regulation and on translational control. The mechanism by which a liver-specific microRNA regulates hepatitis C virus genome replication is under intense scrutiny. In addition, the mechanism of internal ribosome entry in certain cellular and viral mRNAs and its biological role in growth and development is being investigated.
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David Schneider
Professor of Microbiology and Immunology
Current Research and Scholarly InterestsWe study innate immunity and microbial pathogenesis. We have been studying models for a variety of bacterial infections including: Listeria, Mycobacteria, Salmonella and Streptococcus as well as some fungi, malaria and viruses. Our current focus is to determine how we recover from infections.
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Robert Siegel
Professor (Teaching) of Microbiology and Immunology
Current Research and Scholarly InterestsMy work is primarily involved in medical education and curricular development, especially in the areas of infectious disease, virology, HIV, and molecular biology. Projects included electronic applications to science education, three dimensional model building, service learning, and the development of undergraduate research projects.
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Justin L. Sonnenburg
Alex and Susie Algard Endowed Professor
Current Research and Scholarly InterestsThe goals of the Sonnenburg Lab research program are to (i) elucidate the basic mechanisms that underlie dynamics within the gut microbiota and (ii) devise and implement strategies to prevent and treat disease in humans via the gut microbiota. We investigate the principles that govern gut microbial community function and interaction with the host using a broad range of experimental approaches including studies of microbiomes in diverse human cohorts.
