School of Medicine
Showing 201-300 of 775 Results
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Maurice L. Druzin
Professor of Obstetrics and Gynecology (Maternal Fetal Medicine) and, by courtesy, of Pediatrics
Current Research and Scholarly InterestsAntepartum and intrapartum fetal monitoring Prenatal diagnosis Medical complications of pregnancy, particularly: SLE, hypertension, diabetes, malignancy A.
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Dawn Duane
Clinical Professor, Neurology
Clinical Professor (By courtesy), PediatricsCurrent Research and Scholarly InterestsI am a general pediatric neurologist. My interest is in clinical diagnosis and treatment of common neurologic diseases in pediatric patients and teaching feature doctors, neurologists and pediatric neurologists about pediatric neurology.
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Anne Dubin
Endowed Professor of Pediatric Cardiology
Current Research and Scholarly InterestsArrhythmia management in pediatric heart failure, especially resynchronization therapy in congenital heart disease,Radio frequency catheter ablation of pediatric arrhythmias,
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Noelle Hanako Ebel
Clinical Associate Professor, Pediatrics - Gastroenterology
Current Research and Scholarly InterestsCurrent projects include:
-indications for combined heart-liver transplantation
-mitigating perioperative bleeding during cardiac surgery in children with Alagille syndrome
-congenital heart disease and liver transplantation
-subspecialty advocacy -
Elizabeth Egan
Assistant Professor of Pediatrics (Infectious Diseases) and of Microbiology and Immunology
Current Research and Scholarly InterestsMalaria is a parasitic disease transmitted by mosquitos that is a leading cause of childhood mortality globally. Public health efforts to control malaria have historically been hampered by the rapid development of drug resistance. The goal of our research is to understand the molecular determinants of critical host-pathogen interactions in malaria, with a focus on the erythrocyte host cell. Our long-term goal is to develop novel approaches to prevent or treat malaria and improve child health.
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Yasser El-Sayed, Professor
Charles B. and Ann L. Johnson Professor in the School of Medicine and Professor, by courtesy, of Pediatrics (Neonatology) and of Surgery
Current Research and Scholarly InterestsHigh Risk Obstetrics: preterm labor, preeclampsia, medical and surgical complications of pregnancy, prenatal diagnosis and therapy
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Gregory Enns
Professor of Pediatrics (Genetics)
Current Research and Scholarly Interestsmitochondrial genomics, lysosomal disorders, tandem-mass spectrometry newborn screening, and inborn errors of metabolism presentations and natural history
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Carlos O. Esquivel, M.D., Ph.D.,FACS
Arnold and Barbara Silverman Professor in Pediatric Transplantation and Professor of Surgery (Abdominal Transplantation) and of Pediatrics (Gastroenterology, Hepatology and Nutrition)
Current Research and Scholarly Interests1) Induction of immunotolerance
2) Rejection of liver and intestinal transplantation.
3) Clinical outcomes of children with unresectable liver tumors. -
Jeffrey A. Feinstein, MD, MPH
Dunlevie Family Professor of Pulmonary Vascular Disease and Professor, by courtesy, of Bioengineering
Current Research and Scholarly InterestsResearch interests include (1) computer simulation and modeling of cardiovascular physiology with specific attention paid to congenital heart disease and its treatment, (2) the evaluation and treatment of pulmonary hypertension/pulmonary vascular diseases, and (3) development and testing of medical devices/therapies for the treatment of congenital heart disease and pulmonary vascular diseases.
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Heidi M. Feldman
Ballinger-Swindells Endowed Professor of Developmental and Behavioral Pediatrics
Current Research and Scholarly InterestsMy current research program focuses on infants born preterm, before 32 weeks gestation from two language environments: English and Spanish. The study considers how neurobiological factors, specifically properties of the white matter circuits in the brain, interact with social, psychological, and economic factors to predict language processing efficiency at 18 months of age.
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Nielsen Fernandez-Becker
Clinical Associate Professor, Medicine - Gastroenterology & Hepatology
BioI am the director of the Celiac Disease Program at Stanford and I am highly experienced in diagnosis and management of celiac disease and gluten associated disorders.
My objective is to provide excellent and compassionate clinical care for my patients while seeking a better understanding of diseases I treat, particularly Celiac disease (CeD), eosinophilic esophagitis (EoE). My top priorities are patient care and translational research to make new discoveries and improve the care my patients. -
Michael Fischbach
Liu (Liao) Family Professor
Current Research and Scholarly InterestsThe microbiome carries out extraordinary feats of biology: it produces hundreds of molecules, many of which impact host physiology; modulates immune function potently and specifically; self-organizes biogeographically; and exhibits profound stability in the face of perturbations. Our lab studies the mechanisms of microbiome-host interactions. Our approach is based on two technologies we recently developed: a complex (119-member) defined gut community that serves as an analytically manageable but biologically relevant system for experimentation, and new genetic systems for common species from the microbiome. Using these systems, we investigate mechanisms at the community level and the strain level.
1) Community-level mechanisms. A typical gut microbiome consists of 200-250 bacterial species that span >6 orders of magnitude in relative abundance. As a system, these bacteria carry out extraordinary feats of metabolite consumption and production, elicit a variety of specific immune cell populations, self-organize geographically and metabolically, and exhibit profound resilience against a wide range of perturbations. Yet remarkably little is known about how the community functions as a system. We are exploring this by asking two broad questions: How do groups of organisms work together to influence immune function? What are the mechanisms that govern metabolism and ecology at the 100+ strain scale? Our goal is to learn rules that will enable us to design communities that solve specific therapeutic problems.
2) Strain-level mechanisms. Even though gut and skin colonists live in communities, individual strains can have an extraordinary impact on host biology. We focus on two broad (and partially overlapping) categories:
Immune modulation: Can we redirect colonist-specific T cells against an antigen of interest by expressing it on the surface of a bacterium? How do skin colonists induce high levels of Staphylococcus-specific antibodies in mice and humans?
Abundant microbiome-derived molecules: By constructing single-strain/single-gene knockouts in a complex defined community, we will ask: What are the effects of bacterially produced molecules on host metabolism and immunology? Can the molecular output of low-abundance organisms impact host physiology?
3) Cell and gene therapy. We have begun two new efforts in mammalian cell and gene therapies. First, we are developing methods that enable cell-type specific delivery of genome editing payloads in vivo. We are especially interested in delivery vehicles that are customizable and easy to manufacture. Second, we have begun a comprehensive genome mining effort with an emphasis on understudied or entirely novel enzyme systems with utility in mammalian genome editing. -
Paul Graham Fisher, MD
Beirne Family Professor of Pediatric Neuro-Oncology, Professor of Pediatrics and, by courtesy, of Neurosurgery and of Epidemiology and Population Health
Current Research and Scholarly InterestsClinical neuro-oncology: My research explores the epidemiology, natural history, and disease patterns of brain tumors and other cancers in childhood, as well as prospective clinical trials for treating these neoplasms. Research interests also include neurologic effects of cancer and its therapies.
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Barry Fleisher
Associate Professor of Pediatrics at the Lucile Salter Packard Children's Hospital, Emeritus
Current Research and Scholarly InterestsNeonatology, neurobehavioral development, outcomes in premature infants.
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Eric Foote
Clinical Assistant Professor, Pediatrics - Neonatal and Developmental Medicine
BioEric Foote is a pediatric hospitalist with experience conducting clinical and public health research around the world. His research focuses on identifying and intervening on health disparities in low income countries and in low resource settings. Currently, he is developing and evaluating a community health worker-led household phototherapy intervention to extend access to neonatal jaundice care for newborns in rural Bangladesh. He is also working to improve SARS-CoV-2 testing and genomic surveillance across California and worldwide.
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James Ford
Professor of Medicine (Oncology) and of Genetics and, by courtesy, of Pediatrics
Current Research and Scholarly InterestsMammalian DNA repair and DNA damage inducible responses; p53 tumor suppressor gene; transcription in nucleotide excision repair and mutagenesis; genetic determinants of cancer cell sensitivity to DNAdamage; genetics of inherited cancer susceptibility syndromes and human GI malignancies; clinical cancer genetics of BRCA1 and BRCA2 breast cancer and mismatch repair deficient colon cancer.
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Uta Francke
Professor of Genetics and of Pediatrics, Emerita
Current Research and Scholarly InterestsFunctional consequences and pathogenetic mechanisms of mutations and microdeletions in human neurogenetic syndromes and mouse models. Integration of genomic information into medical care.
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Jennifer Frankovich
Clinical Professor, Pediatrics - Rheumatology
Current Research and Scholarly InterestsMy primary interest and role at Stanford is to evaluate and treat children with both systemic and organ specific autoimmune disease. In October of 2012, we started a multidisciplinary clinic dedicated to treating patients with PANS (Pediatric Acute-onset Neuropsychiatric Syndromes). I am currently the clinical and research director for the PANS program.
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Adam Frymoyer
Clinical Professor, Pediatrics - Neonatal and Developmental Medicine
Clinical Associate Professor, PediatricsCurrent Research and Scholarly InterestsMy research interests focus on understanding the clinical pharmacokinetics (PK) and pharmacodynamics (PD) of medicines used in complex pediatric populations. This includes identifying sources of variation in drug response through the application of population PK-PD modeling and simulation approaches. The goal is to ultimately apply this quantitative understanding to guide therapeutic decision-making in infants and children.
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Janene Fuerch
Clinical Associate Professor, Pediatrics - Neonatal and Developmental Medicine
BioJanene H. Fuerch, MD is a Clinical Associate Professor of Neonatology at Stanford University Medical Center, as well as an innovator, educator, researcher and physician entrepreneur. She has an undergraduate degree in Neuroscience from Brown University and a medical degree from the Jacobs School of Medicine at SUNY Buffalo. At Stanford University she completed a pediatrics residency, neonatal-perinatal medicine fellowship and the Byers Center for Biodesign Innovation Fellowship.
She is also Assistant Director of the Biodesign Innovation Fellowship Program at Stanford University, and Co-Director of Impact1 where she mentors and advises new entrepreneurs through all aspects of medical device development, from identifying clinical needs to commercialization. Her specific areas of investigational interest include the development and commercialization process of neonatal, pediatric and maternal health medical devices as well as the utilization of a simulated environment to develop and test medical devices. She is a national leader in neonatal resuscitation, ECMO, device development and has been an AHRQ and FDA funded investigator. But her work extends outside of the academic realm to industry having co-founded EMME (acquired by Simple Health 2022) an award-winning reproductive health company, medical director for Novonate (acquired by Laborie 2023) a neonatal umbilical catheter securement company and notable consultant for Vitara (EXTEND - artificial environment to decrease complications of prematurity), and Avanos™. Janene is passionate about improving the health of children and newborns through medical device innovation and research. -
Hayley Gans
Clinical Professor, Pediatrics - Infectious Diseases
Current Research and Scholarly InterestsThe focus of my laboratory is the immune response to viral vaccines evaluating the ontogeny of responses in infants and limitations in immunocompromised hosts. We have studied responses to an early two-dose measles immunization, one versus 2 doses of varicella immunization, and polio vaccine in preterm versus term infants. Other active areas of research include measles and varicella immunity in HIV infected individuals, and transplant recipients.
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Chris Garcia
Younger Family Professor and Professor of Structural Biology
Current Research and Scholarly InterestsStructural and functional studies of transmembrane receptor interactions with their ligands in systems relevant to human health and disease - primarily in immunity, infection, and neurobiology. We study these problems using protein engineering, structural, biochemical, and combinatorial biology approaches.
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Christopher Gardner
Rehnborg Farquhar Professor
Current Research and Scholarly InterestsThe role of nutrition in individual and societal health, with particular interests in: plant-based diets, differential response to low-carb vs. low-fat weight loss diets by insulin resistance status, chronic disease prevention, randomized controlled trials, human nutrition, community based studies, Community Based Participatory Research, sustainable food movement (animal rights and welfare, global warming, human labor practices), stealth health, nutrition policy, nutrition guidelines
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Brice Gaudilliere
Associate Professor of Anesthesiology, Perioperative and Pain Medicine (Adult-MSD) and, by courtesy, of Pediatrics (Neonatology)
Current Research and Scholarly InterestsThe advent of high dimensional flow cytometry has revolutionized our ability to study and visualize the human immune system. Our group combines high parameter mass cytometry (a.k.a Cytometry by Time of Flight Mass Spectrometry, CyTOF), with advanced bio-computational methods to study how the human immune system responds and adapts to acute physiological perturbations. The laboratory currently focuses on two clinical scenarios: surgical trauma and pregnancy.
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Charles Gawad
Associate Professor of Pediatrics (Hematology/Oncology)
BioOur lab works at the interface of biotechnology, computational biology, cellular biology, and clinical medicine to develop and apply new tools for characterizing genetic variation across single cells within a tissue with unparalleled sensitivity and accuracy. We are focused on applying these technologies to study cancer clonal evolution while patients are undergoing treatment with the aim of identifying cancer clonotypes that are associated with resistance to specific drugs so as to better understand and predict treatment response. We are also applying these methods to understand how more virulent pathogens emerge from a population of bacteria or viruses with an emphasis on developing a deeper understanding of how antibiotic resistance develops.
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Yael Gernez
Clinical Associate Professor, Pediatrics - Immunology and Allergy
BioMy clinic focuses on solving the molecular puzzles that underlie rare allergic and immunologic diseases to shed light on fundamental principles governing allergy, inflammation and immune system defects. My goal is to find better and safer therapies for my patients with rare diseases that include autoinflammation, autoimmunity and primary immune deficiency. It is important to highlight that every patient requires individualized therapeutic approaches based on their underlying genetic problem and the types and severity of their clinical manifestations. For some patients, a hematopoietic stem cell transplant (HSCT) is curative while for others, a targeted drug therapy, such as a biologic or small molecule agent, is most suitable. In some cases, a truly novel therapy may be required, .e.g., anti-sense oligonucleotide therapy to suppress aberrant gene splicing or adoptive cellular therapy. My passion is to provide the best personalized therapy for our patients with allergy and immunology diseases. This often requires performing very specialized functional assays and in some cases in enlisting laboratories with specific expertise or interest in particular genetic disorders.
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Bertil Glader
Stanford Medicine Professor of Pediatric Hematology/Oncology and Professor, by courtesy, of Pathology
Current Research and Scholarly InterestsHematology/Oncology, biology, and treatment of bone marrow failure disorders, hereditary coagulation disorders-clinical trials.
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Greg Glasscock
Clinical Associate Professor, Pediatrics - Neonatal and Developmental Medicine
Current Research and Scholarly InterestsNeonatal Endocrinology
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Anna L Gloyn
Professor of Pediatrics (Endocrinology) and of Genetics
Current Research and Scholarly InterestsAnna's current research projects are focused on the translation of genetic association signals for type 2 diabetes and glycaemic traits into cellular and molecular mechanisms for beta-cell dysfunction and diabetes. Her group uses a variety of complementary approaches, including human genetics, functional genomics, physiology and islet-biology to dissect out the molecular mechanisms driving disease pathogenesis.
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Neville H. Golden M.D.
Marron and Mary Elizabeth Kendrick Professor of Pediatrics, Emeritus
Current Research and Scholarly InterestsMy research has focused on the medical complications of adolescents with eating disorders. My specific area of study has been the etiology and implications of amenorrhea in adolescents with eating disorders, in particular the management of reduced bone mass and osteoporosis in anorexia nervosa.
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Natalia Gomez-Ospina
Assistant Professor of Pediatrics (Genetics) and of Pediatrics (Stem Cell Transplantation)
Current Research and Scholarly InterestsDr. Gomez-Ospina is a physician scientist and medical geneticist with a strong interest in the diagnosis and management of genetic diseases.
1) Lysosomal storage diseases:
Her research program is on developing better therapies for a large class of neurodegenerative diseases in children known as lysosomal storage disorders. Her current focus is on developing genome editing of hematopoietic stem cells as a therapeutic approach for these diseases beginning with Mucopolysaccharidosis type 1 and Gaucher disease. She established a genetic approach where therapeutic proteins can be targeted to a single well-characterized place in the genome known as a safe harbor. This approach constitutes a flexible, “one size fits all” approach that is independent of specific genes and mutations. This strategy, in which the hematopoietic system is commandeered to express and deliver therapeutic proteins to the brain can potentially change the current approaches to treating childhood neurodegenerative diseases and pave the way for alternative therapies for adult neurodegenerative disorders such as Alzheimer’s and Parkinson’s disease
2) Point of care ammonia testing
She also works in collaboration with other researchers at Stanford to develop point-of-care testing for serum ammonia levels. Such device will greatly improve the quality of life of children and families with metabolic disorders with hyperammonemia.
3) Gene discovery
Dr Gomez-Ospina lead a multi-institutional collaboration resulting in the discovery of a novel genetic cause of neonatal and infantile cholestatic liver disease. She collaborated in the description of two novel neurologic syndromes caused by mutations in DYRK1 and CHD4.
For more information go to our website:
https://www.gomezospina.com/ -
William Rowland Goodyer, MD/PhD
Assistant Professor of Pediatrics (Cardiology)
BioDr. Goodyer is a physician scientist who specializes in Pediatric Cardiology and Electrophysiology. Will graduated from McGill University (Montreal, Canada) with a BSc in Biology prior to completing his graduate studies at Stanford University in the Medical Scientist Training Program (MSTP). He subsequently completed residency training in Pediatrics at Boston Children’s Hospital before returning to Stanford to complete a fellowship in Pediatric Cardiology and advanced fellowship in Pediatric Electrophysiology. He additionally performed a postdoctoral fellowship in the Sean Wu laboratory at the Stanford Cardiovascular Institute where he developed the first comprehensive single-cell gene atlas of the entire murine cardiac conduction system (CCS) as well as pioneered the generation of optical imaging agents for the real-time visualization of the CCS to help prevent accidental surgical damage during heart surgeries. Will's lab (www.goodyerlab.com) focuses on basic science advances aimed at the improved diagnosis and treatment of cardiac arrhythmias.
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Jeffrey Gould
Robert L. Hess Endowed Professor of Pediatrics
Current Research and Scholarly InterestsPopulation-based studies related to neonatal and perinatal diseases.
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Florette K. Gray Hazard
Professor - University Medical Line, Pathology
Current Research and Scholarly InterestsMy scholarly pursuits are primarily focused on the study of death and disease in the pediatric population. It is through this work that I am able to explore fundamental concepts of neoplasia, such as histogenesis and mutagenesis, while utilizing a variety of investigational techniques.
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Paul C. Grimm
Professor of Pediatrics (Nephrology)
Current Research and Scholarly InterestsComputerized image analysis of kidney and liver biopsies to quantitate and diagnose subtle changes in tissue structure.
Renal Inflammation
Renal Allograft Rejection
Renal Fibrosis in;
-Primary Kidney Disease
-Transplant Kidney Disease
Liver fibrosis
Steatohepatitis -
Monica Grover
Clinical Associate Professor, Pediatrics - Endocrinology and Diabetes
BioCLINICAL FOCUS:
- Pediatric Endocrinology
- Pediatric Diabetes
- Pediatric Bone Health -
Anna H Grummon
Assistant Professor of Pediatrics (General Pediatrics) and, by courtesy, of Health Policy
BioDr. Grummon is an Assistant Professor of Pediatrics and (by courtesy) Health Policy and the Director of the Stanford Food Policy Lab. Dr. Grummon is a behavioral scientist whose work seeks to identify and evaluate policies that encourage healthy eating and help children and their families live long, healthy lives. In her work, Dr. Grummon uses randomized trials, natural experiments, and simulation modeling to examine how food policies like warning labels, beverage taxes, and food assistance programs affect what we eat and how healthy we are. She also studies strategies for encouraging people to choose foods that are more environmentally sustainable. Dr. Grummon's program of research has been funded by the National Institutes of Health, the Robert Wood Johnson Foundation, the New York City Department of Health and Mental Hygiene, and others. Her work has been published in leading medical and public health journals including JAMA, New England Journal of Medicine, Science, and the American Journal of Public Health and received coverage in news outlets such as the Washington Post, NBC, NPR, and Forbes.
Dr. Grummon holds a PhD and MSPH in Health Behavior from the University of North Carolina Gillings School of Global Public Health and a BA with Honors in Human Biology from Stanford. She completed her postdoctoral training at Harvard. -
Christiane Haeffele
Clinical Associate Professor, Medicine - Cardiovascular Medicine
Clinical Assistant Professor, Pediatrics - CardiologyCurrent Research and Scholarly InterestsAdult Congenital Heart Disease
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Bereketeab Haileselassie
Assistant Professor of Pediatrics (Critical Care)
Current Research and Scholarly InterestsMy laboratory is focused on understanding the cellular mechanisms which mediate end-organ failure in pediatric sepsis. Our current work focuses on determining the role of altered mitochondrial dynamics in sepsis-induced multi-organ dysfunction syndrome (MODS). Specifically, we focus on understanding the mechanisms that mediate derangements in mitochondrial fission and autophagy in sepsis.
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Lou Halamek
Professor of Pediatrics (Neonatology) and, by courtesy, of Obstetrics and Gynecology
Current Research and Scholarly Interests1. development of hospital operations centers coupled with sophisticated simulation capabilities
2. re-creation of near misses and adverse events
3. optimizing human and system performance during resuscitation
4. optimizing pattern recognition and situational awareness at the bedside
5. evaluation and optimization of debriefing
6. patient simulator design -
Bonnie Halpern-Felsher
Marron and Mary Elizabeth Kendrick Professor of Pediatrics and Professor, by courtesy, of Epidemiology and Population Health and of Psychiatry and Behavioral Sciences
Current Research and Scholarly InterestsResearch focuses on developmental, cognitive and psychosocial factors involved in adolescents’ and young adults’ health-related decision-making, perceptions of risk and vulnerability, health communication and risk behavior. My research has focused on understanding and reducing health risk behaviors such as tobacco use, alcohol and marijuana use, risky driving, and risky sexual behavior.
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Lawrence D. Hammer
Professor of Pediatrics (General Pediatrics) at the Lucile Salter Packard Children's Hospital, Emeritus
Current Research and Scholarly InterestsDr Hammer has had a longstanding interest in factors influencing the development of childhood obesity. In particular, his studies have focused on early determinants of eating behavior, physical activity, and parenting behavior in relation to early feeding decisions and parental influences on diet and eating. With the current epidemic of child obesity and it's comorbidities, he is currently involved in the development of protocols for adolescent bariatric surgery.
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Maha Hanna
Clinical Assistant Professor, Pediatrics
Current Research and Scholarly InterestsA bad latch means maternal excruciating pain, ineffective milk transfer with subsequent weight loss, hypoglycemia, higher risk of hyperbilirubinemia and dehydration fever.All of the above led to early cessation of breastfeeding; 46% of mothers who initiate exclusive breastfeeding stop within the first 12 weeks because of difficult latch. I developed a latch tutorial focusing on step-by step-in striations for achieving an effective, non-painful latch.
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Geoffrey Hart-Cooper
Clinical Associate Professor, Pediatrics - General Pediatrics
Current Research and Scholarly InterestsDr. Hart-Cooper's research focuses on youth provider barriers and education surrounding pre-exposure prophylaxis for HIV (PrEP). He founded the Virtual PrEP Program for Adolescents and Young Adults at Stanford to improve access to PrEP care for youth within California. In his current role, he advises health departments and health systems in creating youth-focused telehealth tools to improve youth access to PrEP.