School of Medicine
Showing 101-150 of 890 Results
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James D. Brooks
Keith and Jan Hurlbut Professor
Current Research and Scholarly InterestsWe use genomic approaches to identify disease biomarkers. We are most interested in translating biomarkers into clinical practice in urological diseases with a particular focus in cancer.
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Jennifer L. Bruno
Instructor, Psychiatry and Behavioral Sciences - Interdisciplinary Brain Sciences
Current Research and Scholarly InterestsDr. Bruno is a translational researcher at the interface of developmental cognitive neuropsychology and neurobiology. An overarching goal of her work is to understand developmental windows of vulnerability—periods of risk for falling off the trajectory of typical brain development. Her research utilizes genetics, brain imaging, and deep behavioral phenotyping to bridge computational science with clinical knowledge, translating cutting-edge science to solve problems of great clinical need.
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Bruce Buckingham
Professor of Pediatrics (Endocrinology) at the Lucile Salter Packard Children's Hospital, Emeritus
Current Research and Scholarly InterestsMy major interest is in type 1 diabetes mellitus, continuous glucose sensor, and the development of an artificial pancreas. Other research interests include using continuous glucose monitoring and algorithms to control blood glucose levels in intensive care units.
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Marion S. Buckwalter, MD, PhD
Professor of Neurology (Adult Neurology) and of Neurosurgery
Current Research and Scholarly InterestsThe goal of the Buckwalter Lab is to improve how people recover after a stroke. We use basic and clinical research to understand the cells, proteins, and genes that lead to successful recovery of function, and also how complications develop that impact quality of life after stroke. Ongoing projects are focused on understanding how inflammatory responses are regulated after a stroke and how they affect short-term brain injury and long term outcomes like dementia and depression.
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Sujatha Buddhe
Clinical Associate Professor, Pediatrics - Cardiology
Clinical Associate Professor (By courtesy), Radiology - Pediatric RadiologyBioDr. Buddhe earned her medical degree from the Osmania Medical College, Hyderabad, India. She completed her pediatrics residency and chief residency at the Brookdale University Hospital and Medical Center, NY and pediatric cardiology fellowship at the Children's Hospital of Michigan. Her advanced fellowship training in pediatric cardiac non-invasive imaging was completed at the Columbia University College of Physicians and Surgeons, Morgan Stanley Children's Hospital in New York. She earned her Masters degree in Clinical research and statistical analysis at the University of Michigan, Ann Arbor. She worked at Seattle Children's Hospital, University of Washington for almost ten years where she served as the Director of Non-invasive Imaging research and the Co-Director of cardiac MRI program. Her research interests include echocardiography and Cardiac MRI.
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Alex Butwick
Professor of Anesthesiology, Perioperative and Pain Medicine (OB)
On Leave from 07/18/2023 To 07/01/2024Current Research and Scholarly InterestsI perform outcomes-based research in obstetrics investigating strategies to better prevent and treat patients with postpartum hemorrhage, a leading cause of maternal morbidity and mortality. I also have research interests in the use of point-of-care devices for investigating key changes in the maternal hematologic and hemostatic profiles that occur during the peripartum and postpartum periods.
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MyMy Buu
Clinical Associate Professor, Pediatrics - Pulmonary Medicine
Current Research and Scholarly InterestsHer scholarly work has been focused on pediatric health in vulnerable communities. Her current research is pulmonary outcomes of patients with neuromuscular disease. She is involved in clinical trials in patients with neuromuscular disease.
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Christina Buysse
Clinical Associate Professor, Pediatrics
Current Research and Scholarly InterestsTelemedicine to teach pediatrics residents Developmental Behavioral Pediatrics
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Erica P. Cahill MD
Clinical Associate Professor, Obstetrics & Gynecology
Current Research and Scholarly Interestsreproductive and sexual health care and education
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Weidong Cai
Clinical Associate Professor, Psychiatry and Behavioral Sciences
BioMy research focuses on brain mechanisms underlying cognitive deficits in two distinct populations: children with neurodevelopmental disorders, especially kids with ADHD, and elders with neurodegenerative diseases, such as Parkinson's disease. By integrating cognitive, neuroscience, and computational models with advanced functional neuroimaging techniques, my goal is to understand the neurocognitive factors that contribute to typical and atypical brain development and aging.
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Alison Callahan
Instructor, Medicine - Biomedical Informatics Research
BioAlison Callahan is an Instructor in the Center for Biomedical Informatics and Clinical Data Scientist in the Stanford Health Care Data Science team led by Nigam Shah. Her current research uses informatics to expand and improve the data available about pregnancy and birth, and to develop and maintain and EHR-derived obstetric database. She is also the co-leader of the OHDSI Perinatal & Reproductive Health (PRHeG) working group. Her work in the SHC Data Science team focuses on developing and implementing methods to assess and identify high value applications of machine learning in healthcare settings.
Alison completed her PhD in the Department of Biology at Carleton University in Ottawa, Canada. Her doctoral research focused on developing HyQue, a framework for representing and evaluating scientific hypotheses, and applying this framework to discover genes related to aging. She was also a developer for Bio2RDF, an open-source project to build and provide the largest network of Linked Data for the life sciences. Her postdoctoral work at Stanford applied methodologies developed during her PhD to study spinal cord injury in model organisms and humans in a collaboration with scientists at the University of Miami. -
Michele Calos
Professor of Genetics, Emerita
Current Research and Scholarly InterestsMy lab is developing innovative gene and stem cell therapies for genetic diseases, with a focus on gene therapy and regenerative medicine.
We have created novel methods for inserting therapeutic genes into the chromosomes at specific places by using homologous recombination and recombinase enzymes.
We are working on 3 forms of muscular dystrophy.
We created induced pluripotent stem cells from patient fibroblasts, added therapeutic genes, differentiated, and engrafted the cells. -
David Camarillo
Associate Professor of Bioengineering and, by courtesy, of Neurosurgery and of Mechanical Engineering
BioDavid B. Camarillo is Associate Professor of Bioengineering, (by courtesy) Mechanical Engineering and Neurosurgery at Stanford University. Dr. Camarillo holds a B.S.E in Mechanical and Aerospace Engineering from Princeton University, a Ph.D. in Mechanical Engineering from Stanford University and completed postdoctoral fellowships in Biophysics at the UCSF and Biodesign Innovation at Stanford. Dr. Camarillo worked in the surgical robotics industry at Intuitive Surgical and Hansen Medical, before launching his laboratory at Stanford in 2012. His current research focuses on precision human measurement for multiple clinical and physiological areas including the brain, heart, lungs, and reproductive system. Dr. Camarillo has been awarded the Hellman Fellowship, the Office of Naval Research Young Investigator Program award, among other honors including multiple best paper awards in brain injury and robotic surgery. His research has been funded by the NIH, NSF, DoD, as well as corporations and private philanthropy. His lab’s research has been featured on NPR, the New York Times, The Washington Post, Science News, ESPN, and TED.com as well as other media outlets aimed at education of the public.
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Andres Cardenas
Assistant Professor of Epidemiology and Population Health and, by courtesy, of Pediatrics
BioI am an environmental epidemiologist and serve as an Assistant Professor in the Department of Epidemiology and Population Health at Stanford University. I joined the faculty at Stanford School of Medicine in 2022.
My research focuses on characterizing molecular and epigenetic biomarkers and the extent to which these alterations contribute to disease risk throughout the life course. My group utilizes computational approaches to investigate environmental chemical mixtures, biological aging markers and fetal epigenetic programming. We have several studies looking at chemical and non-chemical stressors in early-life and subsequent health including; neurodevelopment, obesity and immune function.
My research examines the intersection of chemical and social environments in shaping health and disease. -
Jan Carette
Professor of Microbiology and Immunology
Current Research and Scholarly InterestsOur research focuses on the identification of host genes that play critical roles in the pathogenesis of infectious agents including viruses. We use haploid genetic screens in human cells as an efficient approach to perform loss-of-function studies. Besides obtaining fundamental insights on how viruses hijack cellular processes and on host defense mechanisms, it may also facilitate the development of new therapeutic strategies.
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Jennifer Carlson
Clinical Professor, Pediatrics - Adolescent Medicine
BioJennifer Carlson, MD, is a Clinical Professor of Pediatrics in the division of Adolescent Medicine at Stanford. During her time at Stanford, she has served in a range of both clinical roles (providing care in the ambulatory, inpatient, and consultative services) and educational roles (serving as rotation director, pediatric resident coach, program director for Adolescent Medicine fellowship, member of the Fellows in Adolescent Medicine Learning Initiative (FAMLI)). She has led/collaborated on program initiatives with the goal of improving health access, particularly for the adolescent-aged population. These programs have included the Virtual PrEP clinic, inpatient Reproductive Consultation service, outpatient Joint Reproductive Health clinics, and Eating Disorders Telehealth program.
In addition to Adolescent Medicine, Dr. Carlson is board-certified in Clinical Informatics. She has served as the Medical Director of Patients Portals since 2016 and is a member of the Epic Adolescent Medicine Steering Board/BrainTrust. In her role as Clinical Informaticist, she has worked to expand and enhance information access for patients and families and published widely on novel approaches to portal development and management of confidentiality within the electronic health record (EHR). She has collaborated on the Epic White paper for managing confidentiality within the EHR and co-authored a multi-organization position statement on the topic.
Operationally, Dr. Carlson has held positions as physician-at-large for the LPCH Executive committee, Medical Director of the South Bay clinics, and member of the Operations Leadership Steering committee for the hospital.
Specific areas of interest and scholarship include:
1)Improving health equity and health access for the pediatric population- particularly for the adolescent and young adult age range- through novel program development (such as Virtual PrEP clinic).
2)Developing foundational and systemic approaches to managing health information within the EHR to allow for optimal health care for all patients. This includes ensuring that private and confidential information is protected within the electronic health record and non-private information is easily accessible to patients and families.
3)Improving systems for screening and management of psychosocial factors that affect the health of youth and families (ie, social determinants of health, universal depression screening, etc). -
Suzan L Carmichael, PhD, MS
Professor (Research) of Pediatrics (Neonatology), of Obstetrics & Gynecology (Maternal Fetal Medicine) and, by courtesy, of Epidemiology and Population Health
Current Research and Scholarly InterestsDr. Carmichael is a perinatal and nutritional epidemiologist and Professor of Pediatrics and Obstetrics and Gynecology at the Stanford University School of Medicine.
Her team is committed to finding ways to improve maternal and infant health outcomes and equity by leading research that identifies effective leverage points for change, from upstream 'macro' social and structural factors, to downstream clinical factors (eg, related to care and morbidities) through a collaborative research approach that integrates epidemiologic approaches with community engagement and systems thinking.
Exposure themes include social context, nutrition, care, environmental contaminants and genetics. Outcome themes include severe maternal morbidity, stillbirth, birth defects, and preterm delivery. She is particularly interested in understanding the intersectionality of these varied types of exposures and outcomes and how they interact to impact health and health disparities, for the mother-baby dyad.
Please see the team web-site for further information!
https://med.stanford.edu/carmichaellab.html -
Victor G. Carrión
John A. Turner Endowed Professor for Child and Adolescent Psychiatry
On Partial Leave from 03/01/2024 To 05/31/2024Current Research and Scholarly InterestsExamines the interplay between brain development and stress vulnerability via a multi-method approach that includes psychophysiology, neuroimaging, neuroendocrinology and phenomenology. Treatment development that focuses on individual and community-based interventions for stress related conditions in children and adolescents that experience traumatic stress.
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Thomas Caruso
Clinical Professor, Anesthesiology, Perioperative and Pain Medicine
Current Research and Scholarly InterestsMy research pursuits are focused on system based improvement projects. At Lucile Packard Children's Hospital Stanford, I use system based approaches to improve the quality of care patients receive in the perioperative area and in the ICUs, with a focus on safe transitions of care. Through the Department of Graduate Medical Education at Stanford School of Medicine, I advise residency and fellowship programs on evidence based methods to improve their programs, with a focus on mentorship.
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Brendan Carvalho
Professor of Anesthesiology, Perioperative and Pain Medicine (Adult MSD) and, by courtesy, of Obstetrics and Gynecology (Maternal Fetal Medicine)
Current Research and Scholarly InterestsMy main research interest is in clinical and translational research related to cesarean delivery and labor analgesia as well as maternal-fetal pharmacokinetics and pharmacodynamics drug modeling.
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Alma-Martina Cepika
Instructor, Pediatrics - Stem Cell Transplantation
BioDr. Cepika is an immunologist with an extensive background in translational research, autoimmunity, autoinflammation, and human systems immunology. Her goal is to understand the mechanisms governing immunological tolerance, and to leverage this knowledge to cure currently incurable diseases.
Dr. Cepika received her MD degree and a PhD in Immunology from the University of Zagreb School of Medicine in Croatia. There, she focused on the immunomonitoring of patients with lupus, identifying how circulating DNA levels changed with therapy. Subsequently, she joined the lab of Dr. Virginia Pascual at the Baylor Institute for Immunology Research in Dallas, Texas. Dr. Pascual had previously discovered that IL-1beta is a key pathogenic player in systemic juvenile idiopathic arthritis (sJIA), but the immune alterations contributing to IL-1beta-mediated inflammation remained unknown. To address this, Dr. Cepika developed a 3D in vitro stimulation assay to evaluate immune responses of blood leukocytes of pediatric sJIA patients. In combination with integrated bioinformatics analysis, this approach identified aberrant cellular responses, transcriptional pathways and genes that shed new light on immune dysregulation in sJIA. This assay (tollgene.org) can be further applied to dissect underlying immunopathogenic mechanisms in many human disorders.
Currently, Dr. Cepika is an Instructor in the Pediatric Division of Stem Cell Biology and Regenerative Medicine at Stanford University School of Medicine. There, she is working to uncover the underlying molecular mechanisms that govern the differentiation and function of antigen-inducible regulatory T cells called type 1 regulatory T (Tr1) cells, and use this knowledge to design Tr1 cell-based therapies to improve the outcomes of patients with cancer, autoimmunity, or receiving allogeneic cell or organ transplants. -
Lisa J. Chamberlain
Professor of Pediatrics (General Pediatrics) and, by courtesy, of Education
Current Research and Scholarly InterestsChild Health disparities - Projects focus on elucidating the non-clinical factors that impact access to appropriate care for children with chronic illness.
Health Policy - Projects explore the intersection of medicine as a profession and formation of child health policy. -
Charles Chan
Clinical Assistant Professor, Orthopaedic Surgery
Current Research and Scholarly InterestsDr. Chan's research interests include identifying risk factors for growth plate injuries during ACL reconstruction, developing new strategies to prevent pediatric sports injuries, and clinical outcomes of surgical reconstructions in the pediatric athlete.
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Anne Lynn S. Chang, MD
Professor of Dermatology
Current Research and Scholarly InterestsI have two main research interests:
1) to better understand and treat patients with aggressive basal and squamous cell carcinomas
2) to better understand the genetic and epigenetic mechanisms of healthy human skin aging and to translate these insights into better care of skin diseases enriched in older patients particularly skin cancer and rosacea -
Howard Y. Chang, MD, PhD
Virginia and D. K. Ludwig Professor of Cancer Research and Professor of Genetics
Current Research and Scholarly InterestsOur research is focused on how the activities of hundreds or even thousands of genes (gene parties) are coordinated to achieve biological meaning. We have pioneered methods to predict, dissect, and control large-scale gene regulatory programs; these methods have provided insights into human development, cancer, and aging.
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Stephanie D. Chao, MD FACS FAAP
Associate Professor of Surgery (Pediatric Surgery)
Current Research and Scholarly InterestsDr. Chao is passionate about disease prevention as she believes it is the ultimate way to impact the health of a population. Surgeons often see the devastating, end-results of the failure of prevention. With this perspective, Dr. Chao believes that it is crucial for surgeons to be active in prevention research. Dr. Chao currently serves as Trauma Medical Director of Lucile Packard Children’s Hospital and focuses much of her research on injury prevention.
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Danton Char
Associate Professor of Anesthesiology, Perioperative and Pain Medicine (Pediatric)
Current Research and Scholarly InterestsDr. Char's research is focused on identifying and addressing ethical concerns associated with the implementation of next generation technologies like whole genome sequencing and its attendant technologies like machine learning to bedside clinical care.
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Vivek Charu
Assistant Professor of Pathology and of Medicine (Quantitative Sciences)
BioI am a physician and a biostatistician. My clinical expertise is in the diagnosis of non-neoplastic kidney and liver disease (including transplantation). My research interests center on the design of observational studies and clinical trials, the analysis of observational data, and causal inference.
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Abanti Chaudhuri
Clinical Professor, Pediatrics - Nephrology
BioMedical Director of Pediatric Hypertension program
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Bertha Chen, MD
Professor of Obstetrics and Gynecology (Gynecology - Urogynecology) and, by courtesy, of Urology
Current Research and Scholarly InterestsDr. Chen’s research examines the molecular causes of urinary incontinence and pelvic floor dysfunction. Recognizing that urinary incontinence linked to demise of smooth muscle sphincter function, she is investigating the potential use of stem cell regeneration to restore muscle capacity.
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James K. Chen
Jauch Professor and Professor of Chemical and Systems Biology, of Developmental Biology and of Chemistry
Current Research and Scholarly InterestsOur laboratory combines chemistry and developmental biology to investigate the molecular events that regulate embryonic patterning, tissue regeneration, and tumorigenesis. We are currently using genetic and small-molecule approaches to study the molecular mechanisms of Hedgehog signaling, and we are developing chemical technologies to perturb and observe the genetic programs that underlie vertebrate development.
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Jonathan H. Chen, MD, PhD
Assistant Professor of Medicine (Biomedical Informatics)
Current Research and Scholarly InterestsInformatics solutions ares the only credible approach to systematically address challenges of escalating complexity in healthcare. Tapping into real-world clinical data streams like electronic medical records will reveal the community's latent knowledge in a reproducible form. Delivering this back as clinical decision support will uniquely close the loop on a continuously learning health system.
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Lu Chen
Professor of Neurosurgery and of Psychiatry and Behavioral Sciences
On Leave from 11/01/2023 To 04/30/2024Current Research and Scholarly InterestsWhat distinguishes us humans from other animals is our ability to undergo complex behavior. The synapses are the structural connection between neurons that mediates the communication between neurons, which underlies our various cognitive function. My research program aims to understand the cellular and molecular mechanisms that underlie synapse function during behavior in the developing and mature brain, and how synapse function is altered during mental retardation.
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Sharon F. Chen
Clinical Professor, Pediatrics - Infectious Diseases
Current Research and Scholarly InterestsMy research interest is in viral infections affecting immunocompromised patients. As Co-director of the Pediatric Infectious Diseases Program for Immunocompromised Hosts, I develop and conduct clinical and translational studies to establish best practices for these patients.
My education scholarship interests are in refining active learning to improve student learning, to characterize adaptive expertise of physicians, and to create a tool that assesses "thinking": Stanford CASE -
Alan G. Cheng, MD
Edward C. and Amy H. Sewall Professor in the School of Medicine, Professor of Otolaryngology - Head & Neck Surgery (OHNS) and, by courtesy, of Pediatrics
Current Research and Scholarly InterestsActive Wnt signaling maintains somatic stem cells in many organ systems. Using Wnt target genes as markers, we have characterized distinct cell populations with stem cell behavior in the inner ear, an organ thought to be terminally differentiated. Ongoing work focuses on delineating the developing significance of these putative stem/progenitor cells and their behavior after damage.
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Albert Sean Chiou, MD, MBA
Clinical Associate Professor, Dermatology
Current Research and Scholarly InterestsI am a clinical researcher interested in evaluating promising new diagnostic paradigms and treatments for serious or poorly treated, chronic skin conditions. My research currently includes:
Therapeutics:
- Treatments for itch from epidermolysis bullosa
- Treatments for chronic wounds for patients with recessive dystrophic epidermolysis bullosa (In collaboration with Dr. Jean Tang and Dr. Peter Marinkovich)
- Treatments for atopic dermatitis, psoriasis, and other inflammatory skin conditions
Diagnostics:
- Artificial intelligence approaches for melanoma and skin cancer early detection
- Imaging mass spectrometry for skin cancer margin analysis and diagnosis
I collaborate with other faculty within the Stanford Skin Innovation and Interventional Research Group (SIIRG) to conduct investigator initiated and sponsored clinical trials seeking to improve care for important dermatologic diseases
Please learn more about our work at: https://siirg.stanford.edu/ -
Bill Chiu
Associate Professor of Surgery (Pediatric Surgery)
BioDr. Chiu obtained his B.S. degree in Biological Sciences and graduated with Honors from Stanford University. After graduating, he received his Medical Degree at Northwestern University Feinberg School of Medicine, where he remained for his internship and General Surgery residency training. Dr. Chiu completed his Pediatric Surgery training at The Children’s Hospital of Philadelphia. He is an Associate Professor at Stanford University School of Medicine where he has an active research program studying innovative approaches to treat patients with neuroblastoma.
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Valerie Chock
Professor of Pediatrics (Neonatology) and, by courtesy, of Obstetrics and Gynecology (Maternal Fetal Medicine)
Current Research and Scholarly InterestsNeurological monitoring in critically ill infants. Altered hemodynamics in neonates, especially in relation to prematurity, congenital heart disease, and central nervous system injury. Determination of the hemodynamic significance and effects of a patent ductus arteriosus in the preterm infant. Utilizing NIRS (near-infrared spectroscopy) and other technologies for improved monitoring in the NICU.
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Ricky Y. Choi, MD, MPH
Clinical Assistant Professor, Pediatrics - General Pediatrics
BioRicky Y. Choi, MD, MPH is Clinical Assistant Professor at the Stanford University School of Medicine in the Division of General Pediatrics where he attends on the newborn nursery service and in outpatient clinic. He also leads digital health initiatives for the Division. In the past he has served in a number of clinical leadership positions including as the Department Head of Pediatrics at Asian Health Services Community Health Center in Oakland, CA. He has held multiple national physician leadership roles for many years including the Board of Directors for the National Physicians Alliance and as the founding Chair of the Immigrant Child Health Group of the American Academy of Pediatrics. He is a past Fellow of the California HealthCare Foundation Health Care Leadership Program.
In addition to his clinical work, Dr. Choi serves as the Head of Digital Health at Samsung Electronics America where he leads virtual care, strategy and strategic partnerships. Initially based out of Samsung's headquarters in South Korea and now in the Bay Area, Dr. Choi's expertise is in delivering improved clinical and financial outcomes by using consumer technologies to drive health engagement. -
HyeRan Choo
Clinical Associate Professor, Surgery - Plastic & Reconstructive Surgery
BioDr. HyeRan Choo is a Clinical Associate Professor of Plastic and Reconstructive Surgery in the Department of Surgery at Stanford University School of Medicine. She is Director of Neonatal and Pediatric Craniofacial Airway Orthodontics and Dental Sleep Medicine at Lucile Packard Children’s Hospital Stanford. She also directs the Neonatal and Pediatric Craniofacial Airway Orthodontic Fellowship in the Department of Surgery / Division of Plastic and Reconstructive Surgery. She is a Faculty Fellow of the Stanford Byers Center for Biodesign.
After graduating from Seoul National University with a combined degree in Natural Sciences and Dental Surgery in 2002, Dr. Choo received her Dental Medicine degree from the University of Pennsylvania. She completed her orthodontic residency and Masters in Science degree program at the University of Alabama in Birmingham. Following her Craniofacial Fellowship at the Clinical Center of the National Institutes of Health (NIH) / National Institute of Dental and Craniofacial Research (NIDCR), Dr. Choo was recruited as a full-time faculty member at the University of Pennsylvania and The Children’s Hospital of Philadelphia. Dr. Choo joined the faculty of Stanford University School of Medicine in 2016. Dr. Choo is a board-certified craniofacial orthodontist by American Board of Orthodontics since 2008 and became a diplomate of the American Board of Dental Sleep Medicine in 2021.
Dr. Choo’s areas of expertise are non-surgical airway management and facial reconstruction for newborns with cleft and/or Robin Sequence in the Neonatal Intensive Care Unit. Her treatments utilize simple custom-fabricated orthodontic devices to establish a healthy environment to correct neonatal orofacial abnormalities with great respect for natural growth potential of each neonate. She also practices the full scope of pediatric obstructive sleep apnea management as well as orthodontics and dentofacial orthopedics for patients with cleft and craniofacial abnormalities in a multi-disciplinary clinical setting.
Dr. Choo’s treatment philosophy is based on a fundamental understanding of facial growth and oral functions (Biocreative Orthodontic Strategy). Her research focuses on translation of health innovation technology for the advancement of infant orthodontics. She also pioneers the development of skeletal anchorage-based orthodontic and orthopedic treatment strategies for pediatric sleep apnea patients. -
Danny Hung-Chieh Chou
Assistant Professor of Pediatrics (Endocrinology) and, by courtesy, of Chemical and Systems Biology
Current Research and Scholarly InterestsOur research program integrates concepts of chemical biology, protein engineering and structure biology to design new therapeutic leads and generate probes to study biological processes. A key focus of our lab is insulin, an essential hormone in our body to reduce blood glucose levels. We generate synthetic libraries of insulin analogs to select for chemical probes, and investigate natural insulin molecules (e.g. from the venom of fish-hunting cone snails!) to develop novel therapeutic candidates. We are especially interested in using chemical and enzymatic synthesis to create novel chemical entities with enhanced properties, and leverage the strong expertise of our collaborators to apply our skill sets in the fields of cancer biology, immunology and pain research. Our ultimate goal is to translate our discovery into therapeutic interventions in human diseases.
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Gilbert Chu
Professor of Medicine (Oncology) and of Biochemistry
Current Research and Scholarly InterestsAfter shuttering the wet lab, we have focused on: a point-of-care device to measure blood ammonia and prevent brain damage; a human protein complex that juxtaposes and joins DNA ends for repair and V(D)J recombination; and strategies for teaching students and for reducing selection bias in educational programs.
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Henry Chubb
Clinical Assistant Professor, Pediatrics - Cardiology
Current Research and Scholarly Interestshttps://www.researchgate.net/profile/Henry_Chubb
