School of Medicine
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Margaret T. Fuller
Reed-Hodgson Professor in Human Biology and Professor of Genetics and of Obstetrics/Gynecology (Reproductive and Stem Cell Biology)
Current Research and Scholarly InterestsRegulation of stem cell division and self-renewal Cell type specific transcription machinery and regulation of cell differentiation Developmental regulation of cell cycle progression during male meiosis Molecular dissection of the mechanism of cytokinesis.
Instructor, Psychiatry and Behavioral Sciences - Child and Adolescent Psychiatry
Current Research and Scholarly InterestsDr. Fung is a child & adolescent psychiatrist with specialized clinical training in autism spectrum disorder (ASD) and advanced research training in chemical engineering, neuropsychopharmacology, and neuroimaging. He has extensive work experience in pharmaceutical research and development, including the discovery and development of a GABA(A) receptor agonist for the treatment of insomnia and anxiety.
Dr. Fung serves as a co-investigator and co-protocol director of a current randomized controlled trial of pregnenolone in children and adolescents with ASD. Dr. Fung is interested in elucidating the mechanisms of action of pregnenolone and its related neurosteroids in the treatment of individuals with ASD.
In addition to pharmacologic treatment studies in ASD and other developmental disorders, he is also performing multimodal neuroimaging studies in these disorders. Dr. Fung employs state-of-the-art multimodal neuroimaging tools to study GABA neurophysiology in individuals with ASD, fragile X syndrome (FXS) and intellectual disability. He is the Principal Investigator of NIH-funded "GABAergic Neurophysiology in Autism Spectrum Disorder". He serves as a Co-investigator of "Cross-Species Multi-Modal Neuroimaging to Investigate GABA Physiology in Fragile X Syndrome".
His overarching goal is to dissect the neurobiology of ASD using a combination of bioanalytical, immunochemical, and multimodal imaging techniques to identify biomarkers based on specific molecular mechanisms that will inform targeted treatments for ASD.
Adjunct Professor, Institute for Immunity, Transplantation and Infection
BioDavid Furman obtained his Doctoral degree in immunology (summa cum laude) from the School of Medicine, University of Buenos Aires, Argentina, for his work on cancer immune-surveillance. During his Postdoc at the laboratory of Professor Mark M Davis, (Stanford) he conducted cutting-edge research in Data Science and Systems Immunology to answer scientific questions with strong potential for translational medicine, including the effect of aging, gender and common viral infections in immune system functioning. Dr. Furman’s work focuses in Data Science applied to inflammation and aging. Before joining as an Adjunct Investigator at the National Scientific and Research Council (CONICET), Buenos Aires, Argentina, Dr Furman was a Senior Scientist at the Institute for Immunity, Transplantation and Infection (ITI), Stanford, and his work involved the use of high-bandwidth/high-throughput technologies and Machine Learning tools to better define the human immune system. Since 2016, Dr David Furman holds an Adjunct Professor position at the same institute.