School of Medicine
Showing 71-80 of 92 Results
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Derick Okwan
Assistant Professor of Pathology
Current Research and Scholarly InterestsBroadly, the Okwan lab’s primary interest is to understand how and why the immune system contributes to nearly all chronic diseases. The immune system of the modern human has evolved from a history of stress to the species: famines, continual bouts of lethal pandemics, as well as major climate/environmental and migratory changes that exposed the immune system to novel threats. At the forefront of these challenges are innate immune cells, particularly neutrophils, the most abundant leukocytes. For the first time in human history – at least in the western world- we live in an era of abundance. The Okwan lab is interested in understanding how this traumatic history creates a functional mismatch for the neutrophil, which we believe underpins their roles in chronic diseases of the modern era: cancer, cardiovascular disease, neurodegeneration, and autoimmune disorders. Rather than wholesale depletion of neutrophils and innate immune cells, we seek to identify novel approaches to leverage these cells to combat various diseases.
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Meeta Raman Patel
Adjunct Clinical Assistant Professor, Pediatrics - Gastroenterology
BioDr. Patel has been working with children with autism and other disabilities for over 20 years. She is a Board Certified Behavior Analyst. Dr. Patel received a BS degree from the University of California at Davis in 1996 in Psychology with an emphasis in Biology. She continued her graduate training in Psychology at the University of Nevada, Reno. Dr. Patel received her PhD in Psychology with an emphasis in Behavior Analysis.
She completed a post-doctoral fellowship at the Kennedy Krieger Institute and Johns Hopkins University School of Medicine in 2001. Dr. Patel joined the faculty at the Marcus and Kennedy Krieger Institutes in 2001 and Emory University School of Medicine in 2002. Dr. Patel was a case manager in the Pediatric Feeding Disorders and Early Intervention Programs at the Marcus and Kennedy Krieger Institutes from 2001-2003. In 2003, she started Clinic 4 Kidz, which is a home-based Interdisciplinary Pediatric Feeding Disorders Program. Currently, she serves as the Executive Director of Clinic 4 Kidz.
Her research and clinical interests focus on treating feeding problems in children who have underlying medical issues (e.g., prematurity, failure to thrive [FTT], tube dependence, gastroesophageal reflux [GER], food allergies, etc.). In addition, she has expertise in working with children with autism, more specifically treating food selectivity by type and/or texture.
She currently serves on the editorial board of Behavioral Development which is a journal of the American Psychological Association. She formerly served on the editorial boards for the Journal of Applied Behavior Analysis and Education and Treatment of Children. Dr. Patel also serves as a guest reviewer for several journals. She has published over 20 research studies in peer-reviewed journals and has authored two invited book chapters. Dr. Patel has also been invited to present at numerous conferences and at various hospitals all over the country. -
David A. Relman
Thomas C. and Joan M. Merigan Professor and Professor of Microbiology and Immunology
Current Research and Scholarly InterestsMy investigative program focuses on human-microbe interactions and human microbial ecology, and primarily concerns the ecology of human indigenous microbial communities; a secondary interest concerns the classification of humans with systemic infectious diseases, based on features of genome-wide gene transcript abundance patterns and pther aspects of the host response.
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Michael J Rosen, MD, MSCI
Stanford University Endowed Professor for Pediatric IBD and Celiac Disease
BioDr. Rosen is a pediatric gastroenterologist and physician scientist who has been devoted to advancing inflammatory bowel disease (IBD) research and care for 25 years. He is the inaugural Stanford University Endowed Professor for Pediatric IBD and Celiac Disease. He is also Director of the Stanford Medicine Children’s Health Center for IBD and Celiac Disease, which has achieved nationally leading clinical outcomes under his direction. Dr. Rosen’s research expertise crosses mucosal immunology and epithelial biology and clinical and translational investigation. His NIH-funded laboratory has demonstrated the protective role for type 2 cytokines in chronic intestinal inflammation and advanced intestinal organoids as a model to study IBD. His clinical research has demonstrated how proactive therapeutic drug monitoring can be incorporated into clinical practice to optimize ant-TNF therapy treatment response. Dr. Rosen led the multicenter ARCH Study, which demonstrated the importance of intensified anti-TNF drug dosing in pediatric acute severe ulcerative colitis. Presently, he is co-principal investigator for the Crohn's & Colitis Foundation’s Cohort for Pediatric Translational and Clinical Research in IBD (CAPTURE IBD) which will advance precision medicine for children with IBD.
After graduating from Duke University, Dr. Rosen attended Harvard Medical School, followed by pediatrics residency at Boston Children’s Hospital and Boston Medical Center. He pursued his pediatric gastroenterology fellowship at Vanderbilt University Medical Center, where he received a Master of Science in Clinical Investigation. He started his faculty career at Vanderbilt and then moved to Cincinnati Children’s Hospital and the University of Cincinnati College of Medicine. There he rose to Medical Director of the Schubert Martin IBD Center and Associate Director for Faculty Development in the Gastroenterology division before moving to Stanford in 2021. Dr. Rosen serves on the editorial board for Inflammatory Bowel Diseases and the National Scientific Advisory Committee for the Crohn’s & Colitis Foundation. Outside of work, Dr. Rosen enjoys spending time with his wife and two children at their activities, watching movies, downhill skiing, and getting outside. -
Nazish Sayed MD, PhD
Assistant Professor (Research) of Surgery (Vascular Surgery)
Current Research and Scholarly InterestsThe Sayed Laboratory is focused on the development of novel technologies that drive innovation in regenerative medicine, disease modeling, and drug testing in vascular biology. The lab conducts translational research in vascular biology and aims to understand the role of the vasculature in the development of cardiac diseases, including those due to inherited genetic variants or environmental insults such as type 2 diabetes or hypertension. The lab employs the human induced pluripotent stem cell (iPSC) technology to generate patient-specific vascular cells (endothelial and vascular smooth muscle cells) as an alternative to animal models providing a human tissue surrogate for research that is scalable and sustainable. By employing this unique platform, the lab also investigates the role of chemotherapeutic agents (anti-cancer drugs) on the vasculature. Dr. Sayed’s lab has also established an endothelial regeneration program, where they leverage the innate immune system to regenerate endothelial cells from human fibroblasts.
Work from the lab has led to seminal discoveries in the areas of 1) Nitric oxide (NO) biology, (2) vascular biology, (3) stem cell biology, (4) cardiovascular disease modeling (5) cardio-oncology.
