SLAC National Accelerator Laboratory
Showing 1-13 of 13 Results
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Darya Marchany-Rivera
Staff Engineer 2, Stanford Synchrotron Radiation Lightsource
Current Role at StanfordBeamline Scientist- SMB MC
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Derek Mendez
Staff Scientist - Biomedicine, Stanford Synchrotron Radiation Lightsource
Current Role at StanfordComputational staff scientist at the Stanford Synchrotron Radiation Lightsource (SSRL), in the Macromolecular Crystallography group (Structural and Molecular Biology division).
Main activities revolve around a 3 year BRaVE-funded project to build a new X-ray resource for the acceleration of medicines development (XMeD). Active in-silico areas of research are in the characterization of crystallization outcomes, virtual and experimental screening of ligands, in-silico methods for lead molecule optimization, and extremely sensitive absorption profile characterization using machine learning techniques. A major computational goal is to determine the most valuable tools (and develop new ones) for future XMeD users.
Beyond XMeD, we are focusing on using GPUs and machine learning models to accelerate processing and characterization of user diffraction data that is collected at SSRL beamlines 12-1, 12-2, 14-1, and 9-2. In addition, we are aiming to make available to users new methods that process X-ray diffraction data at the pixel-level in order to extract more information to better resolve structural changes in proteins arising from e.g., binding events and light/chemical driven dynamics.
We are also partnering with NERSC to build a framework for our beamline users to offload computationally intensive jobs to the Perlmutter GPU cluster. -
Patrick Gerald Mitchell
Cryo-EM Engineer, Stanford Synchrotron Radiation Lightsource
Current Role at StanfordDirector of Operations at the Stanford-SLAC CryoEM Center
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Samsuzzoha Mondal
Research Assoc - CryoEM/Bioimg, Stanford Synchrotron Radiation Lightsource
BioSamsuzzoha Modal is a Research Associate at SLAC National Accelerator Laboratory and a Ph.D. chemist specializing in advanced microscopy and biophysical chemistry. His research integrates protein engineering, structural biology, and quantitative imaging to understand how protein organization across length scales regulates biological activity, and to translate these mechanistic insights into therapeutic and diagnostic approaches.
Samsuzzoha earned his Ph.D. at the Tata Institute of Fundamental Research (Mumbai, India), where he developed chemical tools to image signaling phospholipid dynamics in live biological systems. He then completed postdoctoral training at the University of Pennsylvania (Philadelphia), building in vitro reconstitution models to study the molecular basis of membrane trafficking. Since 2023 at SLAC, he has been combining X‑ray crystallography, small‑angle X‑ray scattering, and advanced optical methods to uncover design principles for quantum biosensing tools and to support structure‑guided small‑molecule therapeutic development.
A committed educator and mentor, Samsuzzoha has taught bioanalytical chemistry and led diverse student teams, emphasizing inclusive, hands‑on training, reproducible data practices, and translational problem‑solving.
