SLAC National Accelerator Laboratory
Showing 81-100 of 154 Results
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Derek Mendez
Staff Scientist, SLAC National Accelerator Laboratory
Current Role at StanfordComputational staff scientist at the Stanford Synchrotron Radiation Lightsource (SSRL), in the Macromolecular Crystallography group (Structural and Molecular Biology division).
Main activities revolve around a 3 year BRaVE-funded project to build a new X-ray resource for the acceleration of medicines development (XMeD). Active in-silico areas of research are in the characterization of crystallization outcomes, virtual and experimental screening of ligands, in-silico methods for lead molecule optimization, and extremely sensitive absorption profile characterization using machine learning techniques. A major computational goal is to determine the most valuable tools (and develop new ones) for future XMeD users.
Beyond XMeD, we are focusing on using GPUs and machine learning models to accelerate processing and characterization of user diffraction data that is collected at SSRL beamlines 12-1, 12-2, 14-1, and 9-2. In addition, we are aiming to make available to users new methods that process X-ray diffraction data at the pixel-level in order to extract more information to better resolve structural changes in proteins arising from e.g., binding events and light/chemical driven dynamics.
We are also partnering with NERSC to build a framework for our beamline users to offload computationally intensive jobs to the Perlmutter GPU cluster. -
Despina Milathianaki
Development Manager, SLAC National Accelerator Laboratory
BioDespina is the director of the Office of Technology Transfer and Strategic Partnerships, in the organization of the SLAC Deputy Director for Science and Technology. She and her team help accelerate the translation of cutting-edge research into transformative technologies and solutions through collaborations with industry, academia, and government partners. Before her current role, Despina served as senior director for Department of Energy partnerships in the quantum computing industry establishing important R&D efforts between the private sector and the national labs. Prior roles in the private sector included management consulting for Accenture UK and engineering for a Silicon valley startup. Despina first joined SLAC in 2010 as a staff scientist at the Linac Coherent Light Source investigating materials science at extreme conditions. She later transitioned to strategic planning where she served as the director of strategic planning and investment for SLAC. Despina holds a Bachelor's in Physics from Imperial College London and a Master’s in Electrical Engineering from the University of Michigan. She completed her PhD in High Energy Density Physics at the University of Texas at Austin, conducting research at Lawrence Livermore National Laboratory.
