My research program lies at the intersection of education policy and early childhood development.
I research (1) family processes which impact young children’s learning and wellbeing (2) how to improve children’s learning and wellbeing when they are experiencing daily challenges at home such as family disability, family illness, or difficult relationships. My research informs the design of school- and government-based policies that support young children’s educational success.
Beginning in the Summer of 2021, I will be entering the academic job market for assistant professor positions at research universities. If you are interested in my work, please contact me at firstname.lastname@example.org!
Jelena Obradovic, Doctoral (Program)
The Physiologic and Emotional Effects of 360-Degree Video Simulation on Head-Mounted Display Versus In-Person Simulation: A Noninferiority, Randomized Controlled Trial.
Simulation in healthcare : journal of the Society for Simulation in Healthcare
INTRODUCTION: A key simulation component is its capability to elicit physiological changes, improving recall. The primary aim was to determine whether parasympathetic responses to head-mounted display simulations (HMDs) were noninferior to in-person simulations. The secondary aims explored sympathetic and affective responses and learning effectiveness.METHODS: The authors conducted a noninferiority trial. Hospital providers who did not use chronotropic medications, have motion sickness, or have seizures were included. The authors randomized participants to in-person or HMD simulation. Biometric sensors collected respiratory sinus arrhythmia and skin conductance levels to measure parasympathetic and sympathetic states at baseline, during, and after the simulation. Affect was measured using a schedule. The authors measured 3-month recall of learning points and used split-plot analysis of variance and Mann-Whitney U tests to analyze.RESULTS: One hundred fifteen participants qualified, and the authors analyzed 56 in each group. Both groups experienced a significant change in mean respiratory sinus arrhythmia from baseline to during and from during to afterward. The difference of change between the groups from baseline to during was 0.134 (95% confidence interval = 0.142 to 0.410, P = 0.339). The difference of change from during the simulation to after was -0.060 (95% confidence interval = -0.337 to 0.217, P = 0.670). Noninferiority was not established for either period. Sympathetic arousal did not occur in either group. Noninferiority was not established for the changes in affect that were demonstrated. The mean scores of teaching effectiveness and achievement scores were not different.CONCLUSIONS: Although a parasympathetic and affective response to the video simulation on an HMD did occur, it was not discernibly noninferior to in-person in this study.
View details for DOI 10.1097/SIH.0000000000000587
View details for PubMedID 34120135
Early and concurrent home stimulation: Unique and indirect links with fine motor skills among 4-year-old children in rural Pakistan.
2021; 57 (6): 888-899
Fine motor skills enable children to make precise and coordinated movements with their hands and support their ability to engage in everyday activities and learning experiences. In a longitudinal study of 1,058 4-year-old children in rural Pakistan (n = 488 girls), we examined how prior and concurrent levels of home stimulation relate to change in fine motor skills from ages 2 to 4 while controlling for family wealth, maternal education, number of siblings at birth, prior and concurrent measures of children's physical growth and food insecurity, and prior motor skills at age 2. Moreover, we tested whether the association between early home stimulation and subsequent fine motor skills was mediated by physical growth, food insecurity, motor skills at age 2, and concurrent home stimulation. Results revealed that home stimulation at 18 months was positively associated with change in fine motor skills from ages 2 to 4, over and above family socioeconomic resources. This association was mediated by physical growth, food insecurity and motor skills at age 2. In contrast to home stimulation at 18 months, home stimulation at age 4 was positively associated with concurrent motor skills at age 4 when controlling for all antecedent family factors, as well as prior and concurrent measures of physical growth and food insecurity, and prior motor skills at age 2. Findings suggest that the preschool period may be an important window of time when physically and cognitively stimulating experiences at home uniquely relate to variability in fine motor development. (PsycInfo Database Record (c) 2021 APA, all rights reserved).
View details for DOI 10.1037/dev0001185
View details for PubMedID 34424007
Family Assistance Spills Over Into Prosocial Behaviors Toward Friends and Positive Academic Behaviors.
Journal of research on adolescence : the official journal of the Society for Research on Adolescence
We investigate how daily family assistance predicts prosocial behaviors toward friends and positive academic behavior. Adolescents (N=375, 57% girls, Mage =14.57) completed diary checklists for 14days, reporting whether they provided instrumental assistance or emotional support to family and friends, and their positive academic behaviors (e.g., studied). When adolescents provided emotional support to family, they were more likely to provide instrumental support to friends the next day. When adolescents provided emotional support to family, they were more likely to also provide emotional support to friends the next day, and vice versa (a bidirectional association). When adolescents provided instrumental support to the family, they were more likely to have at least one positive academic experience the next day.
View details for DOI 10.1111/jora.12629
View details for PubMedID 34041807
Neurophysiological Contributors to Advantageous Risk-Taking: An Experimental Psychopharmacological Investigation.
Social cognitive and affective neuroscience
The ability to learn from experience is critical for determining when to take risks and when to play it safe. However, we know little about how within-person state changes, such as an individual's degree of neurophysiological arousal, may impact the ability to learn which risks are most likely to fail vs. succeed. To test this, we used a randomized, double-blind, placebo-controlled design to pharmacologically manipulate neurophysiological arousal and assess its causal impact on risk-related learning and performance. Eighty-seven adults (45% female, Mage= 20.1 ± 1.46 years) took either propranolol (n= 42), a beta-adrenergic receptor blocker that attenuates sympathetic nervous system-related signaling, or a placebo (n= 45). Participants then completed the Balloon Emotional Learning Task, a risk-taking task wherein experiential learning is necessary for task success. We found that individuals on propranolol, relative to placebo, earned fewer points on the task, suggesting that they were less effective risk-takers. This effect was mediated by the fact that those on propranolol made less optimal decisions in the final phase of the task on trials with the greatest opportunity for advantageous risk-taking. These findings highlight how neurophysiological arousal supports risk-related learning and, in turn, more advantageous decision-making and optimal behavior under conditions of risk.
View details for DOI 10.1093/scan/nsab047
View details for PubMedID 33860790
Young Children's Prosocial Behavior Protects Against Academic Risk in Neighborhoods With Low Socioeconomic Status.
Children raised in neighborhoods with low socioeconomic status (SES) are at risk for low academic achievement. Identifying factors that help children from disadvantaged neighborhoods thrive is critical for reducing inequalities. We investigated whether children's prosocial behavior buffers concurrent and subsequent academic risk in disadvantaged neighborhoods in Bradford, UK. Diverse children (N=1,175) were followed until age seven, with measurements taken at four times. We used governmental indices of neighborhood-level SES, teacher observations of prosocial behaviors, and direct assessments of academic achievement. Neighborhood SES was positively associated with academic achievement among children with low levels of prosocial behavior, but not among children with high levels of prosocial behavior. Prosocial behavior may mitigate academic risk across early childhood.
View details for DOI 10.1111/cdev.13549
View details for PubMedID 33594683
Daily provision of instrumental and emotional support to friends is associated with diurnal cortisol during adolescence.
This study investigates how adolescents' daily prosocial behaviors to friends are related to diurnal cortisol using between- and within-subject analyses. Further, we examine whether role fulfillment (i.e., feeling like a good friend) moderates links between prosocial behaviors and cortisol. Ethnically diverse adolescents (N=370; ages 11-18) reported whether they provided instrumental and emotional support to friends for 5days, and provided four saliva samples/day for 4days. On the daily level, providing emotional support predicted lower cortisol awakening response the next day, and providing instrumental assistance to friends was associated with a flatter cortisol slope the same day (a cardiovascular risk factor). Adolescents also provided more emotional support on days they had lower CAR and steeper cortisol slopes. On the average level, providing more instrumental support was associated with steeper cortisol slopes among adolescents who felt high levels of role fulfillment, but not among adolescents who felt low levels of role fulfillment. Providing instrumental support may be physiologically taxing from day to day but, across the long term, linked to lower cardiovascular risk for adolescents who experience helping as highly fulfilling.
View details for DOI 10.1002/dev.22101
View details for PubMedID 33569768
- Genetics and Child Development: Recent Advances and Their Implications for Developmental Research CHILD DEVELOPMENT PERSPECTIVES 2021
- Advancing Measurement and Research on Youths' Prosocial Behavior in the Digital Age CHILD DEVELOPMENT PERSPECTIVES 2021
Beta-adrenergic blockade blunts inflammatory and antiviral/antibody gene expression responses to acute psychosocial stress.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology
Dysregulation of the immune system is one potential mechanism by which acute stress may contribute to downstream disease etiology and psychopathology. Here, we tested the role of β-adrenergic signaling as a mediator of acute stress-induced changes in immune cell gene expression. In a randomized, double-blind, and placebo-controlled trial, 90 healthy young adults (44% female) received a single 40 mg dose of the β-blocker propranolol (n = 43) or a placebo (n = 47) and then completed the Trier Social Stress Test (TSST). Pre- and post-stress blood samples were assayed for prespecified sets of pro-inflammatory and antiviral/antibody gene transcripts. Analyses revealed increased expression of both inflammatory and antiviral/antibody-related genes in response to the TSST, and these effects were blocked by pre-treatment with propranolol. Bioinformatics identified natural killer cells and dendritic cells as the primary cellular context for transcriptional upregulation, and monocytes as the primary cellular carrier of genes downregulated by the TSST. These effects were in part explained by acute changes in circulating cell types. Results suggest that acute psychosocial stress can induce an "acute defense" molecular phenotype via β-adrenergic signaling that involves mobilization of natural killer cells and dendritic cells at the expense of monocytes. This may represent an adaptive response to the risk of acute injury. These findings offer some of the first evidence in humans that β-blockade attenuates psychosocial stress-induced increases in inflammatory gene expression, offering new insights into the molecular and immunologic pathways by which stress may confer risks to health and well-being.
View details for DOI 10.1038/s41386-020-00897-0
View details for PubMedID 33452438
- Self-regulated behavior and parent-child co-regulation are associated with young children's physiological response to receiving critical adult feedback SOCIAL DEVELOPMENT 2020
Addressing educational inequalities and promoting learning through studies of stress physiology in elementary school students.
Development and psychopathology
2020; 32 (5): 1899–1913
To be ready to learn, children need to be focused, engaged, and able to bounce back from setbacks. However, many children come to school with heightened or diminished physiological arousal due to exposure to poverty-related risks. While stress physiology plays a role in explaining how adversity relates to processes that support students' cognitive development, there is a lack of studies of physiological stress response in educational settings. This review integrates relevant studies and offers future directions for research on the role of stress physiology in the school adaptation of elementary school students, focusing on these important questions: (a) What are the links between physiological stress response and learning-related skills and behaviors, and do they vary as a function of proximal and distal experiences outside of school? (b) How are school experiences associated with students' physiological stress response and related cognitive and behavioral adaptations? (c) How can we leverage measures of students' physiological stress response in evaluations of school-based interventions to better support the school success of every student? We hope to stimulate a new wave of research that will advance the science of developmental stress physiology, as well as improve the application of these findings in educational policy and practice.
View details for DOI 10.1017/S0954579420001443
View details for PubMedID 33427176
- Interactions between Polygenic Scores and Environments: Methodological and Conceptual Challenges SOCIOLOGICAL SCIENCE 2020; 7: 465–86
Daily Links Between Helping Behaviors and Emotional Well-Being During Late Adolescence.
Journal of research on adolescence : the official journal of the Society for Research on Adolescence
We investigated daily associations between helping behaviors and emotional well-being during late adolescence, examining whether these links depend on the recipient of help (i.e., friend vs. roommate), type of help (i.e., instrumental vs. emotional), and individual differences in the helper (i.e., gender and empathy). First-year college students (N=411, 63.5% women, Mage =18.62years) completed diary checklists for eight days, reporting whether they provided instrumental and emotional support to a friend or roommate, and positive and negative emotions. On days that adolescents provided instrumental assistance to friends they felt more positive affect, but men also felt more negative affect. Providing instrumental and emotional support to roommates and providing emotional support to friends did not predict daily emotions.
View details for DOI 10.1111/jora.12572
View details for PubMedID 32776635
The Earliest Origins of Genetic Nurture: The Prenatal Environment Mediates the Association Between Maternal Genetics and Child Development.
Observed genetic associations with educational attainment may be due to direct or indirect genetic influences. Recent work highlights genetic nurture, the potential effect of parents' genetics on their child's educational outcomes via rearing environments. To date, few mediating childhood environments have been tested. We used a large sample of genotyped mother-child dyads (N = 2,077) to investigate whether genetic nurture occurs via the prenatal environment. We found that mothers with more education-related genes are generally healthier and more financially stable during pregnancy. Further, measured prenatal conditions explain up to one third of the associations between maternal genetics and children's academic and developmental outcomes at the ages of 4 to 7 years. By providing the first evidence of prenatal genetic nurture and showing that genetic nurture is detectable in early childhood, this study broadens our understanding of how parental genetics may influence children and illustrates the challenges of within-person interpretation of existing genetic associations.
View details for DOI 10.1177/0956797620917209
View details for PubMedID 32484377
Biological sensitivity to context in Pakistani preschoolers: Hair cortisol and family wealth are interactively associated with girls' cognitive skills.
Many young children in low- and middle-income countries (LMICs) face heightened risk for experiencing environmental adversity, which is linked with poorer developmental outcomes. Children's stress physiology can shed light on why children are differentially susceptible to adversity. However, no known studies have examined whether links between adversity and children's development are moderated by children's stress physiology in LMICs. The present study revealed significant interactive effects of hair cortisol concentrations, an index of chronic physiological stress regulation, and family wealth on preschoolers' cognitive skills in rural Pakistan. In a sample of 535 4-year-old children (n=342 girls), we found significant associations between family wealth and direct assessments of verbal intelligence, pre-academic skills, and executive functions only in girls with lower hair cortisol concentrations. Specifically, girls with lower cortisol concentrations displayed greater cognitive skills if they came from relatively wealthier families, but lower cognitive skills if they came from very poor families. There were no significant associations among boys. Results provide evidence of biological sensitivity to context among young girls in a LMIC, perhaps reflecting, in part, sex differences in daily experiences of environmental adversity.
View details for DOI 10.1002/dev.21981
View details for PubMedID 32458442
- Role Fulfillment Mediates the Association Between Daily Family Assistance and Cortisol Awakening Response in Adolescents CHILD DEVELOPMENT 2020; 91 (3): 754–68
Family meals buffer the daily emotional risk associated with family conflict.
Family meals have been associated with positive adolescent outcomes in cross-sectional and longitudinal research. However, it is not known how adolescents experience family meals on a daily basis, and whether family meals buffer stresses associated with interpersonal conflicts on the daily level. To address this gap in the literature, adolescents (N = 396, 58% female, Mage = 14.57 years) completed diary checklists for up to 14 days, reporting their emotions, experiences of family and peer conflict, and whether they ate with their family that day. On days that adolescents shared a family meal, they felt greater happiness and role fulfillment, and less burnout and distress. Moreover, family conflict was associated with more negative emotionality only on days that adolescents did not also eat with the family. Findings suggest that family meals buffer daily risks associated with familial conflicts. Follow-up analyses suggest that these processes may be particularly important among older adolescents. (PsycInfo Database Record (c) 2020 APA, all rights reserved).
View details for DOI 10.1037/dev0001111
View details for PubMedID 32986450
PARENT-CHILD CO-REGULATION AND YOUNG CHILDREN'S PHYSIOLOGICAL RESPONSE TO EMOTIONAL CHALLENGE
WILEY. 2019: S15
View details for Web of Science ID 000494324000056
- A Unifying Approach for Investigating and Understanding Youth's Help and Care for the Family CHILD DEVELOPMENT PERSPECTIVES 2019
BETA-ADRENERGIC BLOCKADE BLUNTS INFLAMMATORY AND ANTIVIRAL/ANTIBODY GENE EXPRESSION RESPONSES TO ACUTE SOCIAL STRESS
LIPPINCOTT WILLIAMS & WILKINS. 2019: A162
View details for Web of Science ID 000467560700453
Role Fulfillment Mediates the Association Between Daily Family Assistance and Cortisol Awakening Response in Adolescents.
Family assistance (helping the family) is associated with both positive and negative psychological and biological outcomes during adolescence. However, the association between family assistance and the hypothalamic-pituitary-adrenal (HPA) axis remains unstudied. Thus, we assess how helping the family relates to adolescents' diurnal cortisol, an index of HPA activity, and psychological outcomes. Three hundred and seventy ethnically diverse adolescents (ages 11-18) reported daily helping behaviors and psychological experiences for 14days and provided four saliva samples per day for 4days. Multilevel modeling revealed that cortisol awakening response was lower the day after adolescents helped their families more. This association was explained, in part, by perceived role fulfillment (feeling like a good son, daughter, and sibling). Results highlight a possible psychological and biological benefit of assisting the family during adolescence.
View details for PubMedID 30629290