How to Design Woke Stroke Tech: The STORIES Project
LIPPINCOTT WILLIAMS & WILKINS. 2020
View details for Web of Science ID 000590040201402
Deep brain optogenetics without intracranial surgery.
Achieving temporally precise, noninvasive control over specific neural cell types in the deep brain would advance the study of nervous system function. Here we use the potent channelrhodopsin ChRmine to achieve transcranial photoactivation of defined neural circuits, including midbrain and brainstem structures, at unprecedented depths of up to 7 mm with millisecond precision. Using systemic viral delivery of ChRmine, we demonstrate behavioral modulation without surgery, enabling implant-free deep brain optogenetics.
View details for DOI 10.1038/s41587-020-0679-9
View details for PubMedID 33020604