Dexterous robotic manipulation of alert adult Drosophila for high-content experimentation.
2015; 12 (7): 657-660
We present a robot that enables high-content studies of alert adult Drosophila by combining operations including gentle picking; translations and rotations; characterizations of fly phenotypes and behaviors; microdissection; or release. To illustrate, we assessed fly morphology, tracked odor-evoked locomotion, sorted flies by sex, and dissected the cuticle to image neural activity. The robot's tireless capacity for precise manipulations enables a scalable platform for screening flies' complex attributes and behavioral patterns.
View details for DOI 10.1038/nmeth.3410
View details for PubMedID 26005812
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