My name is Karlyn (Karly) Edwards, and I am dual research and clinical T32 fellow working with Drs. Beth Darnall and Heather Poupore-King. In my research, I am interested in developing and studying brief digital interventions for chronic pain and opioid misuse/opioid use disorder. I am also interested in characterizing patient factors that facilitate treatment response to OUD medications (buprenorphine, methadone) and psychological interventions. Clinically, I have expertise in delivering acceptance-based interventions (mindfulness, ACT, self-compassion) for chronic pain.

I completed my B.A. in Psychology at the University of Puget Sound in Tacoma, WA in 2014. I then worked as a case manager at a local non-profit mental health agency serving low income communities, and later as a research assistant in Dr. Mark Jensen’s lab at the University of Washington. I completed my Ph.D. in Clinical Psychology at the University of New Mexico under the mentorship of Drs. Kevin Vowles and Katie Witkiewitz, and completed my clinical internship at the Seattle VA. During my PhD, my work focused on characterizing substance use among those with chronic pain, and testing acceptance-based interventions for chronic pain and opioid misuse.

Professional Education

  • Doctor of Philosophy, University of New Mexico (2021)
  • Master of Science, University of New Mexico (2018)
  • Bachelor of Arts, University of Puget Sound (2014)

Stanford Advisors

Research Interests

  • Psychology

Current Research and Scholarly Interests

Adapting and testing psychological interventions for chronic pain and opioid misuse, identifying patients factors related to psychological and medication treatment responsiveness, latent variable modeling, brief digital psychological interventions, Acceptance and Commitment Therapy, Mindfulness

Lab Affiliations

All Publications

  • Changes in Pain During Buprenorphine Maintenance Treatment Among Patients With Opioid Use Disorder and Chronic Pain JOURNAL OF CONSULTING AND CLINICAL PSYCHOLOGY Edwards, K. A., Vowles, K. E., McHugh, R., Venner, K. L., Witkiewitz, K. 2022


    Opioid use disorder (OUD) and chronic pain frequently co-occur. Little is known about changes in pain during buprenorphine/naloxone (BUP/NX) maintenance and whether outcomes vary by pain levels. The present study examined changes in pain intensity and pain interference over 12 weeks of BUP/NX maintenance among participants with OUD and chronic pain (N = 194). Differences in outcomes were assessed during BUP/NX maintenance (Week 12) and 2 months following a BUP/NX taper (Week 24).Data from Phase 2 of the Prescription Opioid Addiction Treatment Study (POATS) were used. Two latent transition models were conducted to characterize profiles and transitions between profiles of pain intensity or pain interference (estimated separately).Each model identified a high and low profile. In the pain interference model, the majority were classified in the low profile at baseline. In the pain intensity model, the majority were classified in the high profile at baseline. In both models, patients were more likely to remain in or transition to the low profiles by Week 12. Worse depression was associated with membership in the high pain interference profile at both timepoints. Women were more likely to be in the high pain intensity profile at baseline. Those in the high pain intensity and high pain interference profiles at Week 12 reported worse mental health quality of life (MH-QOL) at Week 12, as well as high pain intensity and high pain interference at Week 24.For a subgroup of patients, high pain intensity and high pain interference remains unchanged during BUP/NX maintenance treatment. (PsycInfo Database Record (c) 2022 APA, all rights reserved).

    View details for DOI 10.1037/ccp0000692

    View details for Web of Science ID 000740011100001

    View details for PubMedID 35007092