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  • ULTRASOUND CHARACTERIZATION OF BONE DEMINERALIZATION USING A SUPPORT VECTOR MACHINE ULTRASOUND IN MEDICINE AND BIOLOGY Denis, M., Wan, L., Fatemi, M., Alizad, A. 2018; 44 (3): 714–25

    Abstract

    We propose an ultrasound-guided remote measurement technique, utilizing an acoustic radiation force beam as our excitation source and a receiving hydrophone, to assess non-invasively a bone's mechanical properties. Features, such as velocity, were extracted from the acoustic pressure received from the bone surface. The typical velocity of an intact bone (3540 m/s) was higher in comparison to that of a demineralized bone (2231 m/s). According to the receiver operating characteristic curve, the optimal velocity cutoff value of ≥3096 m/s yields 80% sensitivity and 82.61% specificity between intact and demineralized bone. Utilizing a support vector machine, the hours of bone demineralization were successfully classified with maximum accuracy >80% using 18% training data. The results indicate the potential application of our proposed technique and support vector machine for monitoring bone mechanical properties.

    View details for PubMedID 29284556

    View details for PubMedCentralID PMC5801199