Bio


II am the creator and lead director of "Biodesign for Mobile Health"​ since 2012. This experiential, multidisciplinary, project-oriented course has been named by Stanford's Bioengineering "one of the flagship courses of our Department" and has trained over 200 students in a needs-driven process of mobile health technology innovation. The course is offered by the Stanford Byers Center for Biodesign, where I am working with the leadership group under the direct supervision of Paul Yock, MD, Founder and Director of Stanford Biodesign.

With Stanford Biodesign, I am co-leading Biodesign NEXT, an extension funding program designed to recognize the most promising projects by teams of students from select Biodesign courses through additional mentoring and funds to help advance the ideas towards improving health outcomes. I am also a member of Biodesign's Undergraduate Committee and a mentor to Biodesign Fellows and students from all corners of campus who share a passion for health technology innovation. I am motivated to help advance Stanford School of Medicine's work by faculty and students around Digital Health to foster quality research and facilitate the translation of research ideas into medical practice, industry-specific needs and meaningful health outcomes.

biodesign.stanford.edu/bdn/index.jsp

At Stanford, I also have the pleasure to advise on the board of SHIFT, a student initiative aiming to promote and cultivate health innovation on campus by creating a forum for developers, entrepreneurs, and pre-health students to collaborate. A motivated leadership team envisions the group as a platform that connects and empowers students with resources and opportunities to innovate in healthcare. SHIFT fulfills its mission through open roundtable discussions, the TreeHacks Health hackathon and a fellowship program that pairs students as health++ fellows with early-stage companies or faculty-sponsored projects.

shift.stanford.edu

When I am not at Stanford, you'll find me consulting, advising or otherwise engaging with and learning from the startup community of Silicon Valley. I am an equity partner at Data Collective VC, managing director and consultant at Medinnovo LLC, and advisory board member of privately-held companies.

martazanchi.com

Office Address:
Marta Gaia Zanchi
c/o Stanford Biodesign
318 Campus Drive, Room E100
Stanford, CA 93405-5428


"Tell me and I forget, teach me and I may remember, involve me and I learn."
— Benjamin Franklin

Academic Appointments


Administrative Appointments


  • Course lead director, Biodesign for Mobile Health, Stanford Byers Center for Biodesign (2012 - Present)
  • Faculty, Stanford Byers Center for Biodesign (2012 - Present)

Honors & Awards


  • Silicon Valley 40 Under 40, SVBJ (2016)
  • Silicon Valley Women of Influence Award, SVBJ (2016)
  • Medical Device Fellowship, Stanford Byers Center for Biodesign & Food and Drug Administration (Jointly) (2009)
  • Garnier Fellowship Award, Stanford Graduate Business School (2008)
  • Forbes Fellowship Award, Department of Electrical Engineering, Stanford University (2006)
  • Accenture Award, Politecnico Di Milano (2005)
  • Outstanding Graduates of the University Medal, Politecnico Di Milano (2006)

Boards, Advisory Committees, Professional Organizations


  • Member, Advisory Board, Privately Held Companies, Digital Health, Med Tech & Ed Tech (2014 - Present)
  • Member, Advisory Board, SHIFT Health + Tech @ Stanford, http://shift.stanford.edu (2014 - Present)

Professional Education


  • Doctor of Philosophy, Stanford University, Electrical Engineering (2010)

Patents


  • Marta G. Zanchi, Greig C. Scott. "United States Patent 8125270 Frequency offset Cartesian feedback system", The Board of Trustees of the Leland Stanford Junior University
  • Ramtin Agah, Kamran Najmabadi, Marta Gaia Zanchi. "United States Patent 20140276135 Devices, Methods and Kits for Delivery of Therapeutic Materials to a Pancreas", RenovoRX, Inc., Sep 18, 2014

2016-17 Courses


All Publications


  • Medical Device Innovators and the 510(k) Regulatory Pathway: Implications of a Survey-Based Assessment of Industry Experience-Part 2: Medical Device Ecosystem and Policy JOURNAL OF MEDICAL DEVICES-TRANSACTIONS OF THE ASME Pietzsch, J. B., Zanchi, M. G., Linehan, J. H. 2013; 7 (2)

    View details for DOI 10.1115/1.4023131

    View details for Web of Science ID 000326117600051

  • Medical Device Innovators and the 510(k) Regulatory Pathway: Implications of a Survey-Based Assessment of Industry Experience JOURNAL OF MEDICAL DEVICES-TRANSACTIONS OF THE ASME Pietzsch, J. B., Zanchi, M. G., Linehan, J. H. 2012; 6 (2)

    View details for DOI 10.1115/1.4006781

    View details for Web of Science ID 000305270300015

  • Frequency-Offset Cartesian Feedback for MRI Power Amplifier Linearization IEEE TRANSACTIONS ON MEDICAL IMAGING Zanchi, M. G., Stang, P., Kerr, A., Pauly, J. M., Scott, G. C. 2011; 30 (2): 512-522

    Abstract

    High-quality magnetic resonance imaging (MRI) requires precise control of the transmit radio-frequency (RF) field. In parallel excitation applications such as transmit SENSE, high RF power linearity is essential to cancel aliased excitations. In widely-employed class AB power amplifiers, gain compression, cross-over distortion, memory effects, and thermal drift all distort the RF field modulation and can degrade image quality. Cartesian feedback (CF) linearization can mitigate these effects in MRI, if the quadrature mismatch and dc offset imperfections inherent in the architecture can be minimized. In this paper, we present a modified Cartesian feedback technique called "frequency-offset Cartesian feedback" (FOCF) that significantly reduces these problems. In the FOCF architecture, the feedback control is performed at a low intermediate frequency rather than dc, so that quadrature ghosts and dc errors are shifted outside the control bandwidth. FOCF linearization is demonstrated with a variety of typical MRI pulses. Simulation of the magnetization obtained with the Bloch equation demonstrates that high-fidelity RF reproduction can be obtained even with inexpensive class AB amplifiers. Finally, the enhanced RF fidelity of FOCF over CF is demonstrated with actual images obtained in a 1.5 T MRI system.

    View details for DOI 10.1109/TMI.2010.2087768

    View details for Web of Science ID 000286931000029

    View details for PubMedID 20959264

  • Frequency-Offset Cartesian Feedback Based on Polyphase Difference Amplifiers IEEE TRANSACTIONS ON MICROWAVE THEORY AND TECHNIQUES Zanchi, M. G., Pauly, J. M., Scott, G. C. 2010; 58 (5): 1297-1308

    Abstract

    A modified Cartesian feedback method called "frequency-offset Cartesian feedback" and based on polyphase difference amplifiers is described that significantly reduces the problems associated with quadrature errors and DC-offsets in classic Cartesian feedback power amplifier control systems.In this method, the reference input and feedback signals are down-converted and compared at a low intermediate frequency (IF) instead of at DC. The polyphase difference amplifiers create a complex control bandwidth centered at this low IF, which is typically offset from DC by 200-1500 kHz. Consequently, the loop gain peak does not overlap DC where voltage offsets, drift, and local oscillator leakage create errors. Moreover, quadrature mismatch errors are significantly attenuated in the control bandwidth. Since the polyphase amplifiers selectively amplify the complex signals characterized by a +90° phase relationship representing positive frequency signals, the control system operates somewhat like single sideband (SSB) modulation. However, the approach still allows the same modulation bandwidth control as classic Cartesian feedback.In this paper, the behavior of the polyphase difference amplifier is described through both the results of simulations, based on a theoretical analysis of their architecture, and experiments. We then describe our first printed circuit board prototype of a frequency-offset Cartesian feedback transmitter and its performance in open and closed loop configuration. This approach should be especially useful in magnetic resonance imaging transmit array systems.

    View details for DOI 10.1109/TMTT.2010.2045579

    View details for Web of Science ID 000277660200026

  • An Optically Coupled System for Quantitative Monitoring of MRI-Induced RF Currents Into Long Conductors IEEE TRANSACTIONS ON MEDICAL IMAGING Zanchi, M. G., Venook, R., Pauly, J. M., Scott, G. C. 2010; 29 (1): 169-178

    Abstract

    The currents induced in long conductors such as guidewires by the radio-frequency (RF) field in magnetic resonance imaging (MRI) are responsible for potentially dangerous heating of surrounding media, such as tissue. This paper presents an optically coupled system with the potential to quantitatively measure the RF currents induced on these conductors. The system uses a self shielded toroid transducer and active circuitry to modulate a high speed light-emitting-diode transmitter. Plastic fiber guides the light to a photodiode receiver and transimpedance amplifier. System validation included a series of experiments with bare wires that compared wire tip heating by fluoroptic thermometers with the RF current sensor response. Validations were performed on a custom whole body 64 MHz birdcage test platform and on a 1.5 T MRI scanner. With this system, a variety of phenomena were demonstrated including cable trap current attenuation, lossy dielectric Q-spoiling and even transverse electromagnetic wave node patterns. This system should find applications in studies of MRI RF safety for interventional devices such as pacemaker leads, and guidewires. In particular, variations of this device could potentially act as a realtime safety monitor during MRI guided interventions.

    View details for DOI 10.1109/TMI.2009.2031558

    View details for Web of Science ID 000273334400015

    View details for PubMedID 19758855